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List of works by James P. McNamee

A 60 Hz magnetic field does not affect the incidence of squamous cell carcinomas in SENCAR mice

scientific article published in February 2003

Acellular comet assay: a tool for assessing variables influencing the alkaline comet assay

scientific article published on 11 March 2011

Analysis of chromosome damage for biodosimetry using imaging flow cytometry.

scientific article

Analysis of gene expression in mouse brain regions after exposure to 1.9 GHz radiofrequency fields.

scientific article published on 30 March 2016

Analysis of proto-oncogene and heat-shock protein gene expression in human derived cell-lines exposed in vitro to an intermittent 1.9 GHz pulse-modulated radiofrequency field

scientific article published on May 2006

Assessment of genetic damage in peripheral blood of human volunteers exposed (whole-body) to a 200 muT, 60 Hz magnetic field

scientific article published in February 2009

Biological effects of alpha particle radiation exposure on human monocytic cells

scientific article published on 06 December 2011

Chick embryo liver microsomal steroid hydroxylations: induction by dexamethasone, phenobarbital, and glutethimide and inactivation following the in ovo administration of porphyrinogenic compounds

scientific article published on 01 January 1996

Combi-targeting concept: an optimized single-molecule dual-targeting model for the treatment of chronic myelogenous leukemia

scientific article published in May 2008

Comet assay: rapid processing of multiple samples

scientific article

Comments on: "DNA strand breaks" by Diem et al. [Mutat. Res. 583 (2005) 178-183] and Ivancsits et al. [Mutat. Res. 583 (2005) 184-188].

scientific article

Cylindrical waveguide applicator for in vitro exposure of cell culture samples to 1.9-GHz radiofrequency fields

scientific article published on 01 December 2002

Cylindrical waveguide electromagnetic exposure system for biological studies with unrestrained mice at 1.9 GHz.

scientific article published on September 2012

Cytokinetics and mechanism of action of AKO4: a novel nitrogen mustard targeted to bcr-abl

scientific article

DNA damage and apoptosis in the immature mouse cerebellum after acute exposure to a 1 mT, 60 Hz magnetic field

scientific article published in January 2002

Differential rates of cytokine production and apoptosis in venipuncture and finger-stab derived blood cultures

scientific article published on 01 September 2001

Differential responses of EGFR-/AGT-expressing cells to the "combi-triazene" SMA41.

scientific article published on 22 November 2002

Dosimetry evaluation of a cylindrical waveguide chamber for unrestrained small rodents at 1.9 GHz

scientific article

Effect of pro-inflammatory cytokines on spontaneous apoptosis in leukocyte sub-sets within a whole blood culture

scientific article published on 01 July 2005

Effects of alpha particle radiation on gene expression in human pulmonary epithelial cells.

scientific article published on 17 May 2012

Engineering 3-alkyltriazenes to block bcr-abl kinase: a novel strategy for the therapy of advanced bcr-abl expressing leukemias

scientific article

Evaluating DNA damage in rodent brain after acute 60 Hz magnetic-field exposure

scientific article published in December 2005

Evidence for mechanism-based inactivation of rat and chick embryo hepatic cytochrome P4501A and P4503A by dihydropyridines, sydnones, and dihydroquinolines

scientific article published on 01 June 1994

Flow cytometric analysis of micronuclei in peripheral blood reticulocytes: I. Intra- and interlaboratory comparison with microscopic scoring

scientific article published on 03 August 2006

Flow cytometric analysis of micronuclei in peripheral blood reticulocytes: II. An efficient method of monitoring chromosomal damage in the rat.

scientific article published on 3 August 2006

Fractionated X-radiation treatment can elicit an inducible-like radioprotective response that is not dependent on the intrinsic cellular X-radiation resistance/sensitivity

scientific article published on October 2006

Gene expression analysis of a human lymphoblastoma cell line exposed in vitro to an intermittent 1.9 GHz pulse-modulated radiofrequency field.

scientific article published on April 2006

Inactivation of chick embryo hepatic cytochrome P450 1A, 2H and 3A following in ovo administration of 3,5-diethoxycarbonyl-1,4-dihydro-2,6-dimethyl-4-ethylpyridine and 3-[2-(2,4,6-trimethylphenyl)thioethyl]-4-methylsydnone

scientific article published on 01 May 1995

Increased FITC fluorescence on LPS stimulated neutrophils cultured in whole blood

scientific article published on 28 February 2006

Inhibition of cell signaling by the combi-nitrosourea FD137 in the androgen independent DU145 prostate cancer cell line

scientific article published on April 2004

Inhibition of epidermal growth factor receptor-mediated signaling by "Combi-triazene" BJ2000, a new probe for Combi-Targeting postulates

scientific article

Interlaboratory validation of a CD71-based flow cytometric method (Microflow) for the scoring of micronucleated reticulocytes in mouse peripheral blood

scientific article published in January 2005

JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results

scientific article published on 29 April 2015

Mechanism of action of a novel "combi-triazene" engineered to possess a polar functional group on the alkylating moiety: evidence for enhancement of potency

scientific article published on August 2005

Microarray gene expression profiling of a human glioblastoma cell line exposed in vitro to a 1.9 GHz pulse-modulated radiofrequency field

scientific article published on June 2006

Mobile phones, mobile phone base stations and cancer: a review.

scientific article

Multiple mechanisms of action of ZR2002 in human breast cancer cells: a novel combi-molecule designed to block signaling mediated by the ERB family of oncogenes and to damage genomic DNA.

scientific article published in November 2004

No evidence for genotoxic effects from 24 h exposure of human leukocytes to 1.9 GHz radiofrequency fields

scientific article published on 01 May 2003

Quickscan dicentric chromosome analysis for radiation biodosimetry.

scientific article

Relative biological effectiveness of 280 keV neutrons for apoptosis in human lymphocytes

scientific article published on 01 July 2006

Response to pulsed dose rate and low dose rate irradiation with and without mild hyperthermia using human breast carcinoma cell lines

scientific article published on February 2006

Sustained antiproliferative mechanisms by RB24, a targeted precursor of multiple inhibitors of epidermal growth factor receptor and a DNA alkylating agent in the A431 epidermal carcinoma of the vulva cell line.

scientific article published on September 2004

Synthesis of a prodrug designed to release multiple inhibitors of the epidermal growth factor receptor tyrosine kinase and an alkylating agent: a novel tumor targeting concept

scientific article published on December 2003

Thalidomide alters c-MYB and PIM-1 signaling in K-562 cells

scientific article published on 08 March 2006

The apoprotein of cytochrome P450 3A2 does not selectively direct alkylation to one of four pyrrole rings of N-vinylprotoporphyrin IX

scientific article published on 01 August 1996

The combi-targeting concept: Mechanism of action of the pleiotropic combi-molecule RB24 and discovery of a novel cell signaling-based combination principle ⬇️

scientific article published on December 5, 2010

The combi-targeting concept: a novel 3,3-disubstituted nitrosourea with EGFR tyrosine kinase inhibitory properties

scientific article published on November 2002

The combi-targeting concept: dissection of the binary mechanism of action of the combi-triazene SMA41 in vitro and antitumor activity in vivo

scientific article published on 9 September 2004

The combi-targeting concept: in vitro and in vivo fragmentation of a stable combi-nitrosourea engineered to interact with the epidermal growth factor receptor while remaining DNA reactive

scientific article published on January 2007

The combi-targeting concept: selective targeting of the epidermal growth factor receptor- and Her2-expressing cancer cells by the complex combi-molecule RB24.

scientific article published on 26 March 2010

The genotoxicity of mainstream and sidestream marijuana and tobacco smoke condensates

scientific article published in August 2009

Type II combi-molecules: design and binary targeting properties of the novel triazolinium-containing molecules JDD36 and JDE05.

scientific article published on February 2007

Use of a standardized JaCVAM in vivo rat comet assay protocol to assess the genotoxicity of three coded test compounds; ampicillin trihydrate, 1,2-dimethylhydrazine dihydrochloride, and N-nitrosodimethylamine

scientific article published on 26 February 2015

Use of comet and micronucleus assays to measure genotoxicity in meadow voles (Microtus pennsylvanicus) living in golf course ecosystems exposed to pesticides

scientific article published in April 2005

Validation of the cytokinesis-block micronucleus (CBMN) assay for use as a triage biological dosimetry tool.

scientific article

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