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List of works by Matthieu Desroses

Correction to Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors

scientific article

Corrigendum: MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

scientific article published in April 2017

Crystal structure of human MTH1 and the 8-oxo-dGMP product complex

scientific article

Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2

scientific journal article

DXR inhibition by potent mono- and disubstituted fosmidomycin analogues

scientific article

Derivatives of Iressa, a specific epidermal growth factor receptor inhibitor, are powerful apoptosis inducers in PC3 prostatic cancer cells

scientific article published on March 2007

Development of a chemical probe against NUDT15

scientific article published on 20 July 2020

Discovery of novel N-phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high-throughput screening and synthesis

scientific article

Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors

scientific article

Ethionamide boosters: synthesis, biological activity, and structure-activity relationships of a series of 1,2,4-oxadiazole EthR inhibitors

scientific article published on April 2011

Exploring drug target flexibility using in situ click chemistry: application to a mycobacterial transcriptional regulator

scientific article

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

scientific article

Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors

scientific article

Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420.

scientific article

STAT3 differential scanning fluorimetry and differential scanning light scattering assays: Addressing a missing link in the characterization of STAT3 inhibitor interactions

scientific article published on 17 July 2018

Structural analysis of the interaction between spiroisoxazoline SMARt-420 and the Mycobacterium tuberculosis repressor EthR2.

scientific article published on 14 April 2017

Structure-metabolism-relationships in the microsomal clearance of piperazin-1-ylpyridazines

scientific article published on 04 July 2017

Synthetic EthR inhibitors boost antituberculous activity of ethionamide

scientific article

The Next Step Forward in Ubiquitin-Specific Protease 7 Selective Inhibition

scientific article published in December 2017

Vinylic MIDA Boronates: New Building Blocks for the Synthesis of Aza-Heterocycles

scientific article published on 25 March 2015

dUTPase inhibition augments replication defects of 5-Fluorouracil.

scientific article published on April 2017

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