List of works - Nadine Van Roy

A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the human NBPF1 and ACCN1 genes

scientific article

A detailed inventory of DNA copy number alterations in four commonly used Hodgkin's lymphoma cell lines

scientific article (publication date: July 2007)

A multilocus technique for risk evaluation of patients with neuroblastoma

scientific article published on February 2011

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution

scientific article

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

scientific article

Anchoring linkage groups of the Rosa genetic map to physical chromosomes with tyramide-FISH and EST-SNP markers

scientific article

Application of laser capture microdissection in genetic analysis of neuroblastoma and neuroblastoma precursor cells

scientific article

ArrayCGH-based classification of neuroblastoma into genomic subgroups

scientific article published on December 2007

CLL cells respond to B-Cell receptor stimulation with a microRNA/mRNA signature associated with MYC activation and cell cycle progression

scientific article

Chromosome 3p microsatellite allelotyping in neuroblastoma: a report on the technical hurdles

scientific article

Combined karyotyping, CGH and M-FISH analysis allows detailed characterization of unidentified chromosomal rearrangements in Merkel cell carcinoma

scientific article

Demonstration of microchimerism in pregnant sows and effects of congenital PRRSV infection

scientific article

Detection of DNA copy number alterations in cancer by array comparative genomic hybridization

scientific article published on September 2007

EVI1 activation in blast crisis CML due to juxtaposition to the rare 17q22 partner region as part of a 4-way variant translocation t(9;22).

scientific article

EVI1 overexpression in t(3;17) positive myeloid malignancies results from juxtaposition of EVI1 to the MSI2 locus at 17q22.

scientific article

EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells

scientific article published on 14 May 2011

Epidermal growth factor receptor and K-RAS status in two cohorts of squamous cell carcinomas

scientific article

Focal DNA copy number changes in neuroblastoma target MYCN regulated genes

scientific journal article

Focus on 16p13.3 Locus in Colon Cancer

scientific article published on 29 July 2015

Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations

scientific article

Heterogeneous cytogenetic subgroups and outcomes in childhood acute megakaryoblastic leukemia: a retrospective international study

scientific article

High‐risk clonal evolution in chronic B‐lymphocytic leukemia: single‐center interphase fluorescence in situ hybridization study and review of the literature ⬇️

scientific article published on 07 May 2012

Identification of histone H3 clipping activity in human embryonic stem cells

scientific article

Identification of two critically deleted regions within chromosome segment 7q35-q36 in EVI1 deregulated myeloid leukemia cell lines

scientific article

In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis

scientific article published on 7 November 2014

Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type

scientific article

Loss-of-function mutations in LEMD3 result in osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis

scientific article

Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification

scientific article published on 18 August 2010

Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma

scientific article published on 6 December 2015

MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia

scientific article

Molecular basis and clinical significance of genetic aberrations in B-cell precursor acute lymphoblastic leukemia

scientific article published on 19 June 2015

Monosomy 22 and partial loss of INI1 expression in a biphasic synovial sarcoma with an Ewing sarcoma-like poorly differentiated component: Report of a case

scientific article published on 13 April 2016

Multiplex Amplicon Quantification (MAQ), a fast and efficient method for the simultaneous detection of copy number alterations in neuroblastoma

scientific article

N-cadherin in neuroblastoma disease: expression and clinical significance

scientific article

No evidence for involvement of SDHD in neuroblastoma pathogenesis

scientific article

Novel biological insights in T-cell acute lymphoblastic leukemia

scientific article published on 26 June 2015

PHF6 mutations in T-cell acute lymphoblastic leukemia

scientific article (publication date: 14 March 2010)

Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11

scientific article

Predicting outcomes for children with neuroblastoma using a multigene-expression signature: a retrospective SIOPEN/COG/GPOH study

scientific article

Refinement of 1p36 alterations not involving PRDM16 in myeloid and lymphoid malignancies

scientific article

Signaling of ERBB receptor tyrosine kinases promotes neuroblastoma growth in vitro and in vivo

scientific article

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

scientific article

The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia

scientific article

The epigenetic landscape of T-cell acute lymphoblastic leukemia

scientific article published on 28 April 2014

The von Hippel-Lindau tumor suppressor gene expression level has prognostic value in neuroblastoma

scientific article

Thermodynamic framework to assess low abundance DNA mutation detection by hybridization

scientific article

Treatment of human embryos with the TGFβ inhibitor SB431542 increases epiblast proliferation and permits successful human embryonic stem cell derivation

scientific article published on 19 November 2013

Unequivocal delineation of clinicogenetic subgroups and development of a new model for improved outcome prediction in neuroblastoma

scientific article

Unique long non-coding RNA expression signature in ETV6/RUNX1-driven B-cell precursor acute lymphoblastic leukemia

scientific article published on 16 September 2016

Upregulation of MAPK Negative Feedback Regulators and RET in Mutant ALK Neuroblastoma: Implications for Targeted Treatment

scientific article

miRNA expression profiling enables risk stratification in archived and fresh neuroblastoma tumor samples

scientific article

List of works by Nadine Van Roy

A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the human NBPF1 and ACCN1 genes

A detailed inventory of DNA copy number alterations in four commonly used Hodgkin's lymphoma cell lines

A multilocus technique for risk evaluation of patients with neuroblastoma

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Anchoring linkage groups of the Rosa genetic map to physical chromosomes with tyramide-FISH and EST-SNP markers

Application of laser capture microdissection in genetic analysis of neuroblastoma and neuroblastoma precursor cells

ArrayCGH-based classification of neuroblastoma into genomic subgroups

CLL cells respond to B-Cell receptor stimulation with a microRNA/mRNA signature associated with MYC activation and cell cycle progression

Chromosome 3p microsatellite allelotyping in neuroblastoma: a report on the technical hurdles

Combined karyotyping, CGH and M-FISH analysis allows detailed characterization of unidentified chromosomal rearrangements in Merkel cell carcinoma

Demonstration of microchimerism in pregnant sows and effects of congenital PRRSV infection

Detection of DNA copy number alterations in cancer by array comparative genomic hybridization

EVI1 activation in blast crisis CML due to juxtaposition to the rare 17q22 partner region as part of a 4-way variant translocation t(9;22).

EVI1 overexpression in t(3;17) positive myeloid malignancies results from juxtaposition of EVI1 to the MSI2 locus at 17q22.

EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells

Epidermal growth factor receptor and K-RAS status in two cohorts of squamous cell carcinomas

Focal DNA copy number changes in neuroblastoma target MYCN regulated genes

Focus on 16p13.3 Locus in Colon Cancer

Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations

Heterogeneous cytogenetic subgroups and outcomes in childhood acute megakaryoblastic leukemia: a retrospective international study

High‐risk clonal evolution in chronic B‐lymphocytic leukemia: single‐center interphase fluorescence in situ hybridization study and review of the literature ⬇️

Identification of histone H3 clipping activity in human embryonic stem cells

Identification of two critically deleted regions within chromosome segment 7q35-q36 in EVI1 deregulated myeloid leukemia cell lines

In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis

Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type

Loss-of-function mutations in LEMD3 result in osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis

Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification

Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma

MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia

Molecular basis and clinical significance of genetic aberrations in B-cell precursor acute lymphoblastic leukemia

Monosomy 22 and partial loss of INI1 expression in a biphasic synovial sarcoma with an Ewing sarcoma-like poorly differentiated component: Report of a case

Multiplex Amplicon Quantification (MAQ), a fast and efficient method for the simultaneous detection of copy number alterations in neuroblastoma

N-cadherin in neuroblastoma disease: expression and clinical significance

No evidence for involvement of SDHD in neuroblastoma pathogenesis

Novel biological insights in T-cell acute lymphoblastic leukemia

PHF6 mutations in T-cell acute lymphoblastic leukemia

Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11

Predicting outcomes for children with neuroblastoma using a multigene-expression signature: a retrospective SIOPEN/COG/GPOH study

Refinement of 1p36 alterations not involving PRDM16 in myeloid and lymphoid malignancies

Signaling of ERBB receptor tyrosine kinases promotes neuroblastoma growth in vitro and in vivo

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia

The epigenetic landscape of T-cell acute lymphoblastic leukemia

The von Hippel-Lindau tumor suppressor gene expression level has prognostic value in neuroblastoma

Thermodynamic framework to assess low abundance DNA mutation detection by hybridization

Treatment of human embryos with the TGFβ inhibitor SB431542 increases epiblast proliferation and permits successful human embryonic stem cell derivation

Unequivocal delineation of clinicogenetic subgroups and development of a new model for improved outcome prediction in neuroblastoma

Unique long non-coding RNA expression signature in ETV6/RUNX1-driven B-cell precursor acute lymphoblastic leukemia

Upregulation of MAPK Negative Feedback Regulators and RET in Mutant ALK Neuroblastoma: Implications for Targeted Treatment

miRNA expression profiling enables risk stratification in archived and fresh neuroblastoma tumor samples