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List of works by Friedemann Weber

A DNA-based vaccine protects against Crimean-Congo haemorrhagic fever virus disease in a Cynomolgus macaque model

scientific article published on 30 November 2020

A classical bipartite nuclear localization signal on Thogoto and influenza A virus nucleoproteins

scientific article published in October 1998

A comprehensive annotation and differential expression analysis of short and long non-coding RNAs in 16 bat genomes

scientific article published on 30 September 2019

A target on the move: innate and adaptive immune escape strategies of hepatitis C virus

scientific article

A virus-like particle system identifies the endonuclease domain of Crimean-Congo hemorrhagic fever virus

scientific article published on 25 March 2015

Activation of PKR by Bunyamwera virus is independent of the viral interferon antagonist NSs.

scientific article

Activation of innate defense against a paramyxovirus is mediated by RIG-I and TLR7 and TLR8 in a cell-type-specific manner

scientific article

Antigenic drift, antigenic shift and interferon antagonists: how bunyaviruses counteract the immune system

scientific article

Bunyamwera bunyavirus nonstructural protein NSs counteracts the induction of alpha/beta interferon.

scientific article

Bunyamwera virus nonstructural protein NSs counteracts interferon regulatory factor 3-mediated induction of early cell death

scientific article

Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral Cap-Dependent Transcription ⬇️

scientific article published on September 16, 2010

Bunyaviruses and the type I interferon system

scientific article

Comparison of Crimean-Congo Hemorrhagic Fever Virus and Aigai Virus in Life Cycle Modeling Systems Reveals a Difference in L Protein Activity

scientific article published on 13 June 2022

Completion of hepatitis C virus replication cycle in heterokaryons excludes dominant restrictions in human non-liver and mouse liver cell lines.

scientific article

Conserved RNA structures in the intergenic regions of ambisense viruses

scientific article published on 30 November 2017

Conserved vRNA end sequences of Thogoto-orthomyxovirus suggest a new panhandle structure

scientific article published on 01 January 1997

Control of coronavirus infection through plasmacytoid dendritic-cell-derived type I interferon

article by L. Cervantes-Barragan et al published 5 October 2006 in Blood

Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines

scientific article

Crimean-Congo hemorrhagic fever virus delays activation of the innate immune response

scientific article

Differential downregulation of ACE2 by the spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus NL63.

scientific article

Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses

scientific article published on May 2006

Efficient cDNA-based rescue of La Crosse bunyaviruses expressing or lacking the nonstructural protein NSs.

scientific article

Efficient production of Rift Valley fever virus-like particles: The antiviral protein MxA can inhibit primary transcription of bunyaviruses

scientific article

Electron cryo-microscopy and single-particle averaging of Rift Valley fever virus: evidence for GN-GC glycoprotein heterodimers

scientific article published on 4 February 2009

Elongin C Contributes to RNA Polymerase II Degradation by the Interferon Antagonist NSs of La Crosse Orthobunyavirus

scientific article published on 17 March 2020

Evolution and Antiviral Specificities of Interferon-Induced Mx Proteins of Bats against Ebola, Influenza, and Other RNA Viruses.

scientific article published on 10 May 2017

Extracellular 2'-5' oligoadenylate synthetase stimulates RNase L-independent antiviral activity: a novel mechanism of virus-induced innate immunity

scientific article published on 15 September 2010

Ferreting out viral pathogenesis

scientific article published on 01 March 2019

Functional L polymerase of La Crosse virus allows in vivo reconstitution of recombinant nucleocapsids

scientific article published on May 2003

Global suppression of the host antiviral response by Ebola- and Marburgviruses: increased antagonism of the type I interferon response is associated with enhanced virulence

scientific article

High-efficiency detection of severe acute respiratory syndrome virus genetic material

scientific article published on June 2004

Homage to Richard M. Elliott

scientific article published on 10 August 2016

Human Cell Tropism and Innate Immune System Interactions of Human Respiratory Coronavirus EMC Compared to Those of Severe Acute Respiratory Syndrome Coronavirus ⬇️

scientific article published on February 28, 2013

IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA

scientific article

IFIT2 Is an Effector Protein of Type I IFN-Mediated Amplification of Lipopolysaccharide (LPS)-Induced TNF- Secretion and LPS-Induced Endotoxin Shock

ISG15 overexpression compensates the defect of Crimean-Congo hemorrhagic fever virus polymerase bearing a protease-inactive ovarian tumor domain

scientific article published on 15 September 2020

Identification and characterization of short leader and trailer RNAs synthesized by the Ebola virus RNA polymerase

scientific article published in October 2021

Incoming RNA virus nucleocapsids containing a 5'-triphosphorylated genome activate RIG-I and antiviral signaling

scientific article

Induction of DNA damage signaling upon Rift Valley fever virus infection results in cell cycle arrest and increased viral replication

scientific article published on 5 January 2012

Induction of interferon synthesis by the PKR-inhibitory VA RNAs of adenoviruses

scientific article published on January 2006

Influenza virus adaptation PB2-627K modulates nucleocapsid inhibition by the pathogen sensor RIG-I.

scientific article

Inhibition of Beta interferon induction by severe acute respiratory syndrome coronavirus suggests a two-step model for activation of interferon regulatory factor 3.

scientific article

Inhibition of Dugbe nairovirus replication by human MxA protein

scientific article

Inhibition of RNA polymerase II phosphorylation by a viral interferon antagonist

scientific article published on 17 May 2004

Inhibition of SARS-CoV-2 by type I and type III interferons

scientific article published on 25 June 2020

Interaction of severe acute respiratory syndrome-associated coronavirus with dendritic cells

scientific article published in July 2006

Interferon and cytokine responses to Crimean Congo hemorrhagic fever virus; an emerging and neglected viral zonoosis

scientific article published on October 2008

Interferon and cytokine responses to SARS-coronavirus infection

scientific article published on 05 March 2008

Interferon antagonist NSs of La Crosse virus triggers a DNA damage response-like degradation of transcribing RNA polymerase II.

scientific article

Interferon priming enables cells to partially overturn the SARS coronavirus-induced block in innate immune activation

scientific article

Interferon, Mx, and viral countermeasures

scientific article

La Crosse Bunyavirus Nonstructural Protein NSs Serves To Suppress the Type I Interferon System of Mammalian Hosts

scientific article

La Crosse virus (LACV) Gc fusion peptide mutants have impaired growth and fusion phenotypes, but remain neurotoxic

scientific article published on 31 May 2010

Middle East respiratory syndrome coronavirus accessory protein 4a is a type I interferon antagonist

scientific article published on 11 September 2013

Molecular Biology of Rift Valley Fever Virus~!2009-11-04~!2009-11-25~!2010-04-22~!

scholarly article by Michele Bouloy published in May 2010

NSs Protein of Sandfly Fever Sicilian Phlebovirus Counteracts Interferon (IFN) Induction by Masking the DNA-Binding Domain of IFN Regulatory Factor 3

scholarly article by Jennifer Deborah Wuerth et al published 1 December 2018 in Journal of Virology

NSs Virulence Factor of Rift Valley Fever Virus Engages the F-Box Proteins FBXW11 and β-TRCP1 To Degrade the Antiviral Protein Kinase PKR

scientific article published on 27 April 2016

NSs protein of Rift Valley fever virus blocks interferon production by inhibiting host gene transcription

scientific article

NSs protein of rift valley fever virus induces the specific degradation of the double-stranded RNA-dependent protein kinase

scientific article published on 11 February 2009

Neurons produce type I interferon during viral encephalitis

scholarly article

Novel gene product of Thogoto virus segment 6 codes for an interferon antagonist

scientific article

Nuclear pore protein Nup98 is involved in replication of Rift Valley fever virus and nuclear import of virulence factor NSs

scientific article published on 31 October 2019

Omicron variant of SARS-CoV-2 exhibits an increased resilience to the antiviral type I interferon response

scholarly article

Phleboviruses and the Type I Interferon Response

scientific article

Processing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon Induction

scientific article

RIG-I-like receptors and negative-strand RNA viruses: RLRly bird catches some worms

scientific article published on 20 May 2014

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

scientific article (publication date: 10 November 2006)

Recombinant Rift Valley fever viruses encoding bluetongue virus (BTV) antigens: Immunity and efficacy studies upon a BTV-4 challenge

scientific article published on 04 December 2020

Regulatory, biosafety and safety challenges for novel cells as substrates for human vaccines

scientific article

Reverse genetics of SARS-related coronavirus using vaccinia virus-based recombination

scientific article

SUMO modification of TBK1 at the adaptor-binding C-terminal coiled-coil domain contributes to its antiviral activity

scientific article published on 14 October 2014

Second International Conference on Crimean-Congo Hemorrhagic Fever.

scientific article

Segmented negative-strand RNA viruses and RIG-I: divide (your genome) and rule

scientific article

Severe acute respiratory syndrome coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activity

scientific article published on 24 December 2008

Severe fever with thrombocytopenia virus glycoproteins are targeted by neutralizing antibodies and can use DC-SIGN as a receptor for pH-dependent entry into human and animal cell lines

scientific article

Species-independent bioassay for sensitive quantification of antiviral type I interferons

scientific article

Standing on three legs: antiviral activities of RIG-I against influenza viruses

scientific article

Structural basis for encapsidation of genomic RNA by La Crosse Orthobunyavirus nucleoprotein ⬇️

scientific article published on April 15, 2013

Structural insights into RNA encapsidation and helical assembly of the Toscana virus nucleoprotein

scientific article

Structure and function of the Toscana virus cap-snatching endonuclease

scientific article published on 01 November 2019

Structure of Crimean-Congo Hemorrhagic Fever Virus Nucleoprotein: Superhelical Homo-Oligomers and the Role of Caspase-3 Cleavage

scientific article

T7 RNA polymerase-dependent and -independent systems for cDNA-based rescue of Rift Valley fever virus

scientific article

Targeted Mutations in the Fusion Peptide Region of La Crosse Virus Attenuate Neuroinvasion and Confer Protection against Encephalitis

scientific article published on 05 July 2022

The ADP-ribose-1''-monophosphatase domains of severe acute respiratory syndrome coronavirus and human coronavirus 229E mediate resistance to antiviral interferon responses

scientific article published on 27 April 2011

The Bunyamwera virus nonstructural protein NSs inhibits viral RNA synthesis in a minireplicon system

scientific article published on March 2001

The DEVD motif of Crimean-Congo hemorrhagic fever virus nucleoprotein is essential for viral replication in tick cells

scholarly article published by Cristiano Salata in 2018

The International Virus Bioinformatics Meeting 2022

publication published on 05 May 2022

The SARS-CoV-2 N protein is a good component in a vaccine

scientific article published on 13 July 2020

The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors

scientific article

The Short- and Long-Range RNA-RNA Interactome of SARS-CoV-2

scientific article published on 05 November 2020

The antiviral effect of interferon-beta against SARS-coronavirus is not mediated by MxA protein

scientific article published in July 2004

The fourth genus in the Orthomyxoviridae: sequence analyses of two Thogoto virus polymerase proteins and comparison with influenza viruses

scientific article published on August 1997

The interferon antagonist ML protein of thogoto virus targets general transcription factor IIB.

scientific article published on 3 September 2008

The interferon response circuit: induction and suppression by pathogenic viruses

scientific article

The interplays between Crimean-Congo hemorrhagic fever virus (CCHFV) M segment-encoded accessory proteins and structural proteins promote virus assembly and infectivity

scientific article published on 21 September 2020

The intracellular sites of early replication and budding of SARS-coronavirus

scholarly article by Silke Stertz published in May 2007

The secRNome of Listeria monocytogenes Harbors Small Noncoding RNAs That Are Potent Inducers of Beta Interferon

scientific article published on 08 October 2019

Thogoto virus ML protein is a potent inhibitor of the interferon regulatory factor-7 transcription factor

article by N. Buettner et al published 7 October 2009 in Journal of General Virology

Thogoto virus ML protein suppresses IRF3 function

scientific article published in January 2005

Tick-borne encephalitis virus delays interferon induction and hides its double-stranded RNA in intracellular membrane vesicles

scientific article

To Conquer the Host, Influenza Virus Is Packing It In: Interferon-Antagonistic Strategies beyond NS1.

scientific article

Toscana virus induces interferon although its NSs protein reveals antagonistic activity

scientific article published on 22 September 2010

Tula and Puumala hantavirus NSs ORFs are functional and the products inhibit activation of the interferon-beta promoter

scientific article published on October 2007

Vaccination with virus-like particles protects mice from lethal infection of Rift Valley Fever Virus

scientific article published on 20 January 2009

Viperin is an iron-sulfur protein that inhibits genome synthesis of tick-borne encephalitis virus via radical SAM domain activity

scientific journal article

Viral Evasion of the Interferon System: Old Viruses, New Tricks

scholarly article by Friedemann Weber published in April 2003

Viral anti-interferon strategies: mechanisms and clinical impact

Viral immune modulators perturb the human molecular network by common and unique strategies

scientific article

Viral suppression of the interferon system

scientific article published on 27 January 2007

Virulence factor NSs of rift valley fever virus recruits the F-box protein FBXO3 to degrade subunit p62 of general transcription factor TFIIH

scientific article

Virus- and Interferon Alpha-Induced Transcriptomes of Cells from the Microbat Myotis daubentonii

scientific article published on 10 August 2019

Virus-like particles expressing the nucleocapsid gene as an efficient vaccine against Rift Valley fever virus

scientific article published on October 2010

eIF2B as a Target for Viral Evasion of PKR-Mediated Translation Inhibition

scientific article published on 14 July 2020

eIF2B-capturing viral protein NSs suppresses the integrated stress response

scientific article published on 07 December 2021

pH Optimum of Hemagglutinin-Mediated Membrane Fusion Determines Sensitivity of Influenza A Viruses to the Interferon-Induced Antiviral State and IFITMs

scientific article

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