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List of works by Yu Ru Kou

A minimum blood glucose value less than or equal to 120 mg/dL under glycemic control is associated with increased 14-day mortality in nondiabetic intensive care unit patients with sepsis and stress hyperglycemia

scientific article published on 9 April 2016

A simplified prevention bundle with dual hand hygiene audit reduces early-onset ventilator-associated pneumonia in cardiovascular surgery units: An interrupted time-series analysis.

scientific article published on 2 August 2017

AMP-activated protein kinase mediates erythropoietin-induced activation of endothelial nitric oxide synthase

scientific article published on 01 August 2012

Abdominal weight and inspiratory resistance: their immediate effects on inspiratory muscle functions during maximal voluntary breathing in chronic tetraplegic patients

scientific article published in July 1999

Acetylcholine and tachykinin receptor antagonists attenuate wood smoke-induced bronchoconstriction in guinea pigs

scientific article published on November 1998

Activation of P2X purinoceptors by ATP subsequent to an increase in reactive oxygen species causes enhanced laryngeal reflex reactivity in a rat model of extraoesophageal reflux

scientific article published on 02 November 2007

Activation of TRPV1 prevents OxLDL-induced lipid accumulation and TNF-α-induced inflammation in macrophages: role of liver X receptor α.

scientific article published on 26 June 2013

Activation of lung vagal sensory receptors by circulatory endotoxin in rats

scientific article

Activations of TRPA1 and P2X receptors are important in ROS-mediated stimulation of capsaicin-sensitive lung vagal afferents by cigarette smoke in rats

scientific article published on 18 February 2010

Acute effects of cigarette smoke on breathing in rats: vagal and nonvagal mechanisms

scientific article published on 01 March 1990

Acute kidney injury on ventilator initiation day independently predicts prolonged mechanical ventilation in intensive care unit patients.

scientific article published on 28 June 2011

Acute neurogenic airway plasma exudation and edema induced by inhaled wood smoke in guinea pigs: role of tachykinins and hydroxyl radical

scientific article published in April 2000

Additive effect of congenital heart disease and early developmental disorders on attention-deficit/hyperactivity disorder and autism spectrum disorder: a nationwide population-based longitudinal study

scientific article published on 17 April 2017

Afferent vagal pathways mediating respiratory reflexes evoked by ROS in the lungs of anesthetized rats

scientific article published on 10 January 2003

Airway hyperresponsiveness to bronchoconstrictor challenge after wood smoke exposure in guinea pigs

scientific article published in May 2001

Airway inflammation and hypersensitivity induced by chronic smoking.

scientific article

Airway irritation and cough evoked by inhaled cigarette smoke: role of neuronal nicotinic acetylcholine receptors

scientific article published on 18 October 2006

Alleviation of wood smoke-induced lung injury by tachykinin receptor antagonist and hydroxyl radical scavenger in guinea pigs

scientific article

An accurate prediction model to identify undiagnosed at-risk patients with COPD: a cross-sectional case-finding study

scientific article published on 28 May 2019

Analysis of carotid chemoreceptor responses to substance P analogue in anaesthetized cats

scientific article published on 01 March 1995

Annexin A1 mediates the anti-inflammatory effects during the granulocytic differentiation process in all-trans retinoic acid-treated acute promyelocytic leukemic cells.

scientific article

Anti-atherogenic effect of berberine on LXRalpha-ABCA1-dependent cholesterol efflux in macrophages.

scientific article

Anti-inflammatory and neuroprotective effects of triptolide on traumatic brain injury in rats

scientific article published on 17 February 2012

Apocynin attenuates ventilator-induced lung injury in an isolated and perfused rat lung model.

scientific article

Assessment of latent tuberculosis infection in psychiatric inpatients: A survey after tuberculosis outbreaks.

scientific article published on 19 November 2015

Assessment of myocardial injury in the emergency department independently predicts the short-term poor outcome in patients with severe carbon monoxide poisoning receiving mechanical ventilation and hyperbaric oxygen therapy

scientific article published on 22 April 2009

Atrial Fibrillation on Intensive Care Unit Admission Independently Increases the Risk of Weaning Failure in Nonheart Failure Mechanically Ventilated Patients in a Medical Intensive Care Unit: A Retrospective Case-Control Study

scientific article published on May 2016

Bilateral pudendal afferent stimulation improves bladder emptying in rats with urinary retention.

scientific article published on 23 August 2011

Breathing pattern variability: a weaning predictor in postoperative patients recovering from systemic inflammatory response syndrome

scientific article published on 26 November 2003

Carotid body I1-imidazoline receptors: binding, visualization and modulatory function

scientific article published in June 1998

Cell cycle regulation by glucosamine in human pulmonary epithelial cells.

scientific article

Characterization of the transcriptional regulation of the regulator of G protein signaling 2 (RGS2) gene during 3T3-L1 preadipocyte differentiation.

scientific article published on October 2008

Cigarette smoke extract induces COX-2 expression via a PKCalpha/c-Src/EGFR, PDGFR/PI3K/Akt/NF-kappaB pathway and p300 in tracheal smooth muscle cells.

scientific article

Cigarette smoke extract induces HO-1 expression in mouse cerebral vascular endothelial cells: involvement of c-Src/NADPH oxidase/PDGFR/JAK2/STAT3 pathway

scientific article published on November 2010

Cigarette smoke extract induces cytosolic phospholipase A2 expression via NADPH oxidase, MAPKs, AP-1, and NF-kappaB in human tracheal smooth muscle cells

scientific article published in April 2009

Cigarette smoke extract regulates cytosolic phospholipase A2 expression via NADPH oxidase/MAPKs/AP‐1 and p300 in human tracheal smooth muscle cells ⬇️

scientific article published on February 1, 2011

Cigarette smoke extract upregulates heme oxygenase-1 via PKC/NADPH oxidase/ROS/PDGFR/PI3K/Akt pathway in mouse brain endothelial cells.

scientific article

Cigarette smoke particle-phase extract induces HO-1 expression in human tracheal smooth muscle cells: role of the c-Src/NADPH oxidase/MAPK/Nrf2 signaling pathway

scientific article published on 25 February 2010

Comparison of different dosing strategies of intratracheally instilled budesonide on meconium injured piglet lungs.

scientific article published in July 2017

Development of monocyte Toll-like receptor 2 and Toll-like receptor 4 in preterm newborns during the first few months of life

scientific article published on 15 February 2013

Different roles of two subgroups of lung vagal C-fiber afferents in the tachypneic response to pulmonary air embolism in dogs.

scientific article published in December 2000

Differential inducibility of rat pulmonary CYP1A1 by cigarette smoke and wood smoke

scientific article published on 5 May 2006

EGb761 ameliorates the formation of foam cells by regulating the expression of SR-A and ABCA1: role of haem oxygenase-1.

scientific article published on 8 July 2010

Effect of a single breath of cigarette smoke on slowly adapting receptors in canine lungs

scientific article published on 01 April 1992

Effect of arterial chemoreceptor stimulation: role of norepinephrine in hypoxic chemotransmission

scientific article published on 01 January 1993

Effects of Surfactant Lavage Combined With Intratracheal Budesonide Instillation on Meconium-Injured Piglet Lungs

scientific article

Effects of exogenous surfactant supplementation and partial liquid ventilation on acute lung injury induced by wood smoke inhalation in newborn piglets

scientific article published in April 2003

Effects of high thoracic epidural anaesthesia on the peripheral airway reactivity in dogs

scientific article published in January 1998

Effects of partial liquid ventilation with FC-77 on acute lung injury in newborn piglets

scientific article published on 01 January 2002

Eicosapentaenoic acid attenuates cigarette smoke-induced lung inflammation by inhibiting ROS-sensitive inflammatory signaling

scientific article

Enhancing endothelial progenitor cell therapy for critical limb ischemia by extracorporeal shock wave* ⬇️

scientific article published on 01 January 2012

Erythropoietin suppresses the formation of macrophage foam cells: role of liver X receptor alpha

scientific article published on 12 April 2010

Essential role of transient receptor potential vanilloid type 1 in evodiamine-mediated protection against atherosclerosis

scientific article published in October 2012

Evaluating physiological dynamics via synchrosqueezing: prediction of ventilator weaning.

scientific article

Exacerbation of wood smoke-induced acute lung injury by mechanical ventilation using moderately high tidal volume in mice

scientific article published on 22 September 2007

Expression of IL-1β, HMGB1, HO-1, and LDH in malignant and non-malignant pleural effusions

scientific article published on 19 October 2019

G proteins in carotid body chemoreception

scientific article published on 01 September 1995

Ginkgo biloba extract confers protection from cigarette smoke extract-induced apoptosis in human lung endothelial cells: Role of heme oxygenase-1.

scientific article published on 28 February 2009

Glucosamine inhibits IL-1beta-mediated IL-8 production in prostate cancer cells by MAPK attenuation.

scientific article

Glucosamine regulation of LPS-mediated inflammation in human bronchial epithelial cells

scientific article published on 20 March 2010

Glycopyrronium bromide inhibits lung inflammation and small airway remodeling induced by subchronic cigarette smoke exposure in mice.

scientific article published on 28 December 2017

Heart rate variability is associated with survival in patients with brain metastasis: a preliminary report

scientific article published on 12 September 2013

High expression of high-mobility group box 1 in the blood and lungs is associated with the development of chronic obstructive pulmonary disease in smokers.

scientific article published on 24 December 2013

How alcohol impairs the granulocyte expansion during septicemia

scientific article

Hyperlipidemia in COPD is associated with decreased incidence of pneumonia and mortality: a nationwide health insurance data-based retrospective cohort study

scientific article

Hyperthermia increases sensitivity of pulmonary C-fibre afferents in rats.

scientific article

Impact and predictors of prolonged chest tube duration in mechanically ventilated patients with acquired pneumothorax

scientific article published on 7 May 2013

Impaired Cd14 and Cd36 expression, bacterial clearance, and Toll-like receptor 4-Myd88 signaling in caveolin-1-deleted macrophages and mice.

scientific article published on January 2011

Implication of AMP-activated protein kinase in transient receptor potential vanilloid type 1-mediated activation of endothelial nitric oxide synthase

scientific article published on 01 January 2012

Inadequate mechanical ventilation as the first or the second hit in a two-hit model: is there any difference in the injurious impact?

scientific article published on 01 November 2007

Increased risk of preterm birth among women with mitral valve prolapse: a nationwide, population-based study

scientific article published on 23 March 2011

Increased seroprevalence of human herpesvirus 8 in patients with hematological disorders

scientific article published on 01 January 2005

Induction of COX-2/PGE(2)/IL-6 is crucial for cigarette smoke extract-induced airway inflammation: Role of TLR4-dependent NADPH oxidase activation

scientific article published on 3 November 2009

Inflammation and cardio-respiratory control. Foreword

scientific article published on 25 June 2011

Inflammatory Effects of Menthol vs. Non-menthol Cigarette Smoke Extract on Human Lung Epithelial Cells: A Double-Hit on TRPM8 by Reactive Oxygen Species and Menthol.

scientific article

Inflammatory Role of ROS-Sensitive AMP-Activated Protein Kinase in the Hypersensitivity of Lung Vagal C Fibers Induced by Intermittent Hypoxia in Rats

scientific article

Inflammatory role of AMP-activated protein kinase signaling in an experimental model of toxic smoke inhalation injury.

scientific article published in January 2013

Influence of serotonergic mechanisms on the urine flow rate in male rats

scientific article published on 10 September 2014

Inhibitory effect of inhaled wood smoke on the discharge of pulmonary stretch receptors in rats

scientific article published in April 1998

Inhibitory influence of lung vagal C-fiber afferents on the delayed ventilatory response to inhaled wood smoke in rats

scientific article published on 01 January 1996

Inhibitory sympathetic action on the carotid body responses to sustained hypoxia

scientific article published on 01 January 1994

Instability of spontaneous breathing patterns in patients with persistent vegetative state

scientific article

Intensive care unit-acquired bacteremia in mechanically ventilated patients: clinical features and outcomes

scientific article

Intratracheal siRNA for the in vivo silencing of caspase-3: a novel therapy for acute lung injury?

scientific article published on 01 April 2010

Involvement of hydroxyl radical in the immediate ventilatory responses to inhaled wood smoke in rats

scientific article published on 01 January 1997

Involvement of substance P in neutral endopeptidase modulation of carotid body sensory responses to hypoxia

scientific article published on 01 January 2000

Involvement of tachykinin NK(1) and NK(2) receptors in changes in lung mechanics and airway microvascular leakage during the early phase of endotoxemia in Guinea pigs

scientific article published in September 2002

Labour increases the surface expression of two Toll-like receptors in the cord blood monocytes of healthy term newborns

scientific article published on 14 April 2009

Laryngeal C-fiber afferents are not involved in the apneic response to laryngeal wood smoke in anesthetized rats

scientific article published on 01 March 2000

Lung Epithelial TRPA1 Transduces the Extracellular ROS into Transcriptional Regulation of Lung Inflammation Induced by Cigarette Smoke: The Role of Influxed Ca²⁺.

scientific article

Measuring (1,3)-β-D-glucan in tracheal aspirate, bronchoalveolar lavage fluid, and serum for detection of suspected Candida pneumonia in immunocompromised and critically ill patients: a prospective observational study.

scientific article

Mechanisms of cigarette smoke-induced stimulation of rapidly adapting receptors in canine lungs

scientific article published on 01 January 1991

Mechanisms of stimulation of vagal pulmonary C fibers by pulmonary air embolism in dogs

scientific article

Mechanisms of wood smoke-induced increases in nasal airway resistance and reactivity in rats

scientific article published in February 2002

Mechanisms underlying stimulation of rapidly adapting receptors during pulmonary air embolism in dogs

scientific article

Mediator mechanisms involved in TRPV1 and P2X receptor-mediated, ROS-evoked bradypneic reflex in anesthetized rats

scientific article published on 20 April 2006

Mediator mechanisms involved in TRPV1, TRPA1 and P2X receptor-mediated sensory transduction of pulmonary ROS by vagal lung C-fibers in rats.

scientific article published on 5 July 2013

Menthol Cigarette Smoke Induces More Severe Lung Inflammation Than Non-menthol Cigarette Smoke Does in Mice With Subchronic Exposure - Role of TRPM8

scientific article published on 18 December 2018

Menthol suppresses laryngeal C-fiber hypersensitivity to cigarette smoke in a rat model of gastroesophageal reflux disease: the role of TRPM8.

scientific article

Molecular mechanism of curcumin on the suppression of cholesterol accumulation in macrophage foam cells and atherosclerosis

scientific article published on 01 May 2012

Molecular mechanisms of activation of endothelial nitric oxide synthase mediated by transient receptor potential vanilloid type 1.

scientific article

N-arachidonyl dopamine sensitizes rat capsaicin-sensitive lung vagal afferents via activation of TRPV1 receptors.

scientific article

N-terminal domain of soluble epoxide hydrolase negatively regulates the VEGF-mediated activation of endothelial nitric oxide synthase.

scientific article published on 8 November 2011

NADPH Oxidase-Derived ROS Induced by Chronic Intermittent Hypoxia Mediates Hypersensitivity of Lung Vagal C Fibers in Rats

scientific article (publication date: 2016)

Neonatal capsaicin treatment alters immediate ventilatory responses to inhaled wood smoke in rats

scientific article published on 01 August 1999

Neural and hydroxyl radical mechanisms underlying laryngeal airway hyperreactivity induced by laryngeal acid-pepsin insult in anesthetized rats

scientific article published on 01 July 2006

Novel role of AMP-activated protein kinase signaling in cigarette smoke induction of IL-8 in human lung epithelial cells and lung inflammation in mice ⬇️

scientific article published on March 2, 2011

Ozone-induced nasal hyperresponsiveness to tachykinins in guinea pigs

scientific article

Paeonol attenuates cigarette smoke-induced lung inflammation by inhibiting ROS-sensitive inflammatory signaling.

scientific article

Peripheral neural modulation of endotoxin-induced hyperventilation

scientific article published in September 1998

Perivagal antagonist treatment in rats selectively blocks the reflex and afferent responses of vagal lung C fibers to intravenous agonists

scientific article

Possible effect of pneumoperitoneum on the spreading of colon cancer tumor cells

scientific article published on July 1997

Post-intensive care unit respiratory failure in older patients liberated from intensive care unit and ventilator: The predictive value of the National Early Warning Score on intensive care unit discharge

scientific article published on 20 February 2019

Prevention of Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice by Paeonol

scientific article published on 31 March 2017

Prior exercise training alleviates the lung inflammation induced by subsequent exposure to environmental cigarette smoke

scientific article published on 26 March 2012

Prognostic value of plateau pressure below 30 cm H2O in septic subjects with acute respiratory failure

scientific article published on 23 September 2014

Prolonged use of noninvasive positive pressure ventilation after extubation among patients in the intensive care unit following cardiac surgery: The predictors and its impact on patient outcome

scientific article published on 02 July 2019

Protective and defensive airway reflexes evoked by nasal exposure to wood smoke in anesthetized rats

scientific article published on 01 March 2000

Reflex apneic response evoked by laryngeal exposure to wood smoke in rats: neural and chemical mechanisms

scientific article published in September 1997

Reflex changes in breathing pattern evoked by inhalation of wood smoke in rats

scientific article published on 01 June 1994

Regulation of Cigarette Smoke Induction of IL-8 in Macrophages by AMP-activated Protein Kinase Signaling

scientific article published on August 2015

Regulation of LH receptor and PGF2alpha receptor signaling by the regulator of G protein signaling 2 (RGS2) in human and mouse granulosa cells.

scientific article

Resistin increases lipid accumulation by affecting class A scavenger receptor, CD36 and ATP-binding cassette transporter-A1 in macrophages

scientific article published on 14 November 2008

Risk of adverse perinatal outcomes with antithyroid treatment during pregnancy: a nationwide population-based study

scientific article

Role of ATP in the ROS-mediated laryngeal airway hyperreactivity induced by laryngeal acid-pepsin insult in anesthetized rats

scientific article published on 26 February 2009

Role of TRPA1 and TRPV1 in the ROS-dependent sensory irritation of superior laryngeal capsaicin-sensitive afferents by cigarette smoke in anesthetized rats

scientific article

Role of alpha 2-adrenergic receptors in the carotid body response to isocapnic hypoxia

scientific article published on 01 March 1991

Role of bronchopulmonary C-fiber afferents in the apneic response to cigarette smoke

scientific article published on 01 October 1987

Role of interleukin-8 and growth-regulated oncogene-alpha in the chemotactic migration of all-trans retinoic acid-treated promyelocytic leukemic cells toward alveolar epithelial cells

scientific article published on March 2007

Role of lipoxin A4 in the cell-to-cell interaction between all-trans retinoic acid-treated acute promyelocytic leukemic cells and alveolar macrophages.

scientific article published on March 2012

Role of substance P in rat carotid body responses to hypoxia and capsaicin

scientific article published on 01 January 1993

Role of transient receptor potential vanilloid 1 in regulating erythropoietin-induced activation of endothelial nitric oxide synthase

scientific article published on 27 May 2016

Role of vagal afferents in the acute ventilatory responses to inhaled wood smoke in rats

scientific article published on 01 June 1995

Seasonal variation in the incidence of spontaneous pneumothorax and its association with climate: a nationwide population-based study

scientific article

Sensitization by pulmonary reactive oxygen species of rat vagal lung C-fibers: the roles of the TRPV1, TRPA1, and P2X receptors

scientific article

Sensitization of capsaicin-sensitive lung vagal afferents by anandamide in rats: role of transient receptor potential vanilloid 1 receptors

scientific article published on 8 January 2009

Sensory transduction of pulmonary reactive oxygen species by capsaicin-sensitive vagal lung afferent fibres in rats

scientific article published on 31 March 2005

Sexually dimorphic urethral activity in response to pharmacological activation of 5-HT1A receptors in the rat.

scientific article published on 18 September 2013

Smoke-induced airway hyperresponsiveness to inhaled wood smoke in guinea pigs: tachykininergic and cholinergic mechanisms.

scientific article published in January 1998

Stimulation of pulmonary rapidly adapting receptors by inhaled wood smoke in rats

scientific article published in April 1998

Stimulation of rapidly adapting receptors in canine lungs by a single breath of cigarette smoke

scientific article published on March 1990

Stimulation of vagal pulmonary C fibers by inhaled wood smoke in rats

scientific article published in January 1998

Stimulation of vagal pulmonary C-fibers by a single breath of cigarette smoke in dogs

scientific article published on May 1989

Stimulatory effect of circulated nicotine on rapidly adapting receptors in canine lungs

scientific article

Synergistic impact of acute kidney injury and high level of cervical spinal cord injury on the weaning outcome of patients with acute traumatic cervical spinal cord injury

scientific article published on 10 March 2015

Synergistic impact of low serum albumin on intensive care unit admission and high blood urea nitrogen during intensive care unit stay on post-intensive care unit mortality in critically ill elderly patients requiring mechanical ventilation.

scientific article published on 4 June 2012

Tachykinin antagonists in carotid body responses to hypoxia and substance P in the rat.

scientific article published on March 1994

The Risk of Depressive Disorder Among Contacts of Tuberculosis Patients in a TB-endemic Area: A Population-based Cohort Study

scientific article published on October 2015

The Risk of TB in Patients With Type 2 Diabetes Initiating Metformin vs Sulfonylurea Treatment

scientific article

The impact of cancer development on the risk of mycobacterial diseases among rheumatoid arthritis patients

scientific article

The involvement of hydroxyl radical and cyclooxygenase metabolites in the activation of lung vagal sensory receptors by circulatory endotoxin in rats

scientific article published in October 2004

The stimulatory effect of nicotine on vagal pulmonary C-fibers in dogs

scientific article published on 01 June 1989

Transient Receptor Potential Ankyrin 1 Channel Involved in Atherosclerosis and Macrophage-Foam Cell Formation

scientific article published on 25 May 2016

Two subgroups of lung vagal C-fibers with different vulnerabilities to blockades by perivagal capsaicin and vagal cooling in dogs

scientific article published on 01 December 1999

Vagal and mediator mechanisms underlying the tachypnea caused by pulmonary air embolism in dogs

scientific article published on 01 April 2000

Valsartan regulates the interaction of angiotensin II type 1 receptor and endothelial nitric oxide synthase via Src/PI3K/Akt signalling

scientific article published on 23 March 2009

Ventilatory management of acute lung injury by neurally adjusted ventilatory assist and positive end-expiratory pressure

scientific article published on 01 December 2006

Wasabi Compound 6-(Methylsulfinyl) Hexyl Isothiocyanate Induces Cell Death with Coexisting Mitotic Arrest and Autophagy in Human Chronic Myelogenous Leukemia K562 Cells

scientific article published on 23 November 2019

Whole-body moderate hypothermia confers protection from wood smoke-induced acute lung injury in rats: the therapeutic window

scientific article published on 01 April 2006

Wogonin promotes cholesterol efflux by increasing protein phosphatase 2B-dependent dephosphorylation at ATP-binding cassette transporter-A1 in macrophages

scientific article published on 28 December 2010

Wood smoke extract induces oxidative stress-mediated caspase-independent apoptosis in human lung endothelial cells: role of AIF and EndoG.

scientific article published on 17 June 2005

Wood smoke extract promotes both apoptosis and proliferation in rat alveolar epithelial type II cells: the role of oxidative stress and heme oxygenase-1.

scientific article

Wood smoke-induced airway hyperreactivity in guinea pigs: time course, and role of leukotrienes and hydroxyl radical

scientific article published on 01 January 2000

α-Lipoic acid ameliorates foam cell formation via liver X receptor α-dependent upregulation of ATP-binding cassette transporters A1 and G1

scientific article published on 27 October 2010

β Common receptor integrates the erythropoietin signaling in activation of endothelial nitric oxide synthase

scientific article published on 01 December 2011

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