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List of works by Carsten Watzl

2-D DIGE analyses of enriched secretory lysosomes reveal heterogeneous profiles of functionally relevant proteins in leukemic and activated human NK cells

scientific article published in July 2008

2B4 (CD244), NTB-A and CRACC (CS1) stimulate cytotoxicity but no proliferation in human NK cells

scientific article

2B4 engagement mediates rapid LFA-1 and actin-dependent NK cell adhesion to tumor cells as measured by single cell force spectroscopy.

scientific article published on 26 January 2011

A unique secreted adenovirus E3 protein binds to the leukocyte common antigen CD45 and modulates leukocyte functions.

scientific article

Activating NK cell receptor ligands are differentially expressed during progression to cervical cancer.

scientific article

Activating natural cytotoxicity receptors of natural killer cells in cancer and infection

scientific article published on 13 February 2013

Activation of natural killer cells by newcastle disease virus hemagglutinin-neuraminidase

scientific article

Activation of natural killer cells by rituximab in granulomatosis with polyangiitis

scientific article published on 11 December 2019

Active but not inactive granulomatosis with polyangiitis is associated with decreased and phenotypically and functionally altered CD56(dim) natural killer cells

scientific article published on 13 September 2016

Adaptive responses of innate lymphocytes

scientific article published on 01 May 2018

Altered expression of miR-181a and miR-146a does not change the expression of surface NCRs in human NK cells.

scientific article

Altered glycosylation of recombinant NKp30 hampers binding to heparan sulfate: a lesson for the use of recombinant immunoreceptors as an immunological tool

scientific article

Analysis of Natural Killer cell functions in patients with hereditary hemochromatosis

scientific article published on 25 March 2020

Attention to Emotional Information Is Associated With Cytokine Responses to Psychological Stress

article

Blockade of natural killer cell-mediated lysis by NCAM140 expressed on tumor cells

scientific article published on June 2007

CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells

scientific journal article

COVID-19 progression is potentially driven by T cell immunopathogenesis

scientific article published on 03 May 2020

COVID-19-Induced ARDS Is Associated with Decreased Frequency of Activated Memory/Effector T Cells Expressing CD11a+

scientific article published on 08 October 2020

Calibrating a Comprehensive Immune Age Metric to Analyze the Cross Sectional Age-Related Decline in Cardiorespiratory Fitness

scientific article published in 2022

Circulating growth/differentiation factor 15 is associated with human CD56bright natural killer cell dysfunction and nosocomial infection in severe systemic inflammation.

scientific article published on 13 April 2019

Co-Activation of Cultured Human Natural Killer Cells: Enhanced Function and Decreased Inhibition.

scientific article published on January 2016

Coated Latex Beads as Artificial Cells for Quantitative Investigations of Receptor/Ligand Interactions

scientific article published on 01 December 2020

Comparison of phenotype of gammadelta T cells generated using various cultivation methods.

scientific article

Comprehensive analysis of NK cell function in whole blood samples

article

Cutting edge: NTB-A activates NK cells via homophilic interaction

scientific article

Design, Synthesis, and Biological Evaluation of Small, High-Affinity Siglec-7 Ligands: Toward Novel Inhibitors of Cancer Immune Evasion.

scientific article published on 19 January 2017

Designed DNA Surfaces for in Vitro Modulation of Natural Killer Cells

scientific article

Differential Requirements for Src-Family Kinases in SYK or ZAP70-Mediated SLP-76 Phosphorylation in Lymphocytes

scientific article published on 7 July 2017

Enhanced activation of human NK cells by drug-exposed hepatocytes

scientific article published on 14 February 2020

Enhancement of anti-tumor activity in vitro and in vivo by CD150 and SAP

scientific article published on 10 August 2007

Enhancement of natural killer cell effector functions against selected lymphoma and leukemia cell lines by dasatinib

scientific article

Evaluation of Human Natural Killer Cell Activities in Whole Blood ⬇️

scientific article published on 01 November 2010

Executive control, ERP and pro-inflammatory activity in emotionally exhausted middle-aged employees. Comparison between subclinical burnout and mild to moderate depression.

scientific article

Exposing tumor cells to killer cell attack

scientific article published on 01 August 2000

Exposure of NK cells to intravenous immunoglobulin induces IFNγ release and degranulation but inhibits their cytotoxic activity

scientific article published on 13 October 2009

Expression analysis of the ligands for the Natural Killer cell receptors NKp30 and NKp44.

scientific article

F.28. NK Cell Modulation Induced by Intravenous Immunoglobulins

Fine-tuning of immune responses by SLAM-related receptors

scientific article

Glycerol-3-phosphate Acyltransferase 1 Promotes Tumor Cell Migration and Poor Survival in Ovarian Carcinoma.

scientific article published on 26 June 2017

Glycosylation affects ligand binding and function of the activating natural killer cell receptor 2B4 (CD244) protein

scientific article published on 23 May 2011

Guidelines for the use of flow cytometry and cell sorting in immunological studies

scientific article published on October 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

scientific article published on 01 October 2019

Homogenous expression of killer cell immunoglobulin-like receptors (KIR) on polyclonal natural killer cells detected by a monoclonal antibody to KIR2D.

scientific article

How to trigger a killer: modulation of natural killer cell reactivity on many levels

scientific article published on January 2014

Identification of CLEC12B, an inhibitory receptor on myeloid cells.

scientific article

Impact of Biological and Lifestyle Factors on Cognitive Aging and Work Ability in the Dortmund Vital Study: Protocol of an Interdisciplinary, Cross-sectional, and Longitudinal Study

scientific article published on 14 March 2022

Impact of chronic and acute academic stress on lymphocyte subsets and monocyte function.

scientific article published on 16 November 2017

Impedance-based analysis of Natural Killer cell stimulation.

scientific article published on 21 March 2018

Inhibition of NKp30- and 2B4-mediated NK cell activation by evolutionary different human and bovine CEACAM1 receptors.

scientific article

Inhibitory Receptor Signals Suppress Ligation-Induced Recruitment of NKG2D to GM1-Rich Membrane Domains at the Human NK Cell Immune Synapse

scientific article published on 01 May 2007

Integration of activating and inhibitory receptor signaling by regulated phosphorylation of Vav1 in immune cells

scientific article published on 31 May 2011

KIR downregulation by IL-12/15/18 unleashes human NK cells from KIR/HLA-I inhibition and enhances killing of tumor cells

scientific article published on 6 November 2017

LFA-1 Activation in NK Cells and Their Subsets: Influence of Receptors, Maturation, and Cytokine Stimulation.

scientific article published on 18 January 2017

LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer

scientific article published on 07 February 2019

Measuring the immune system: a comprehensive approach for the analysis of immune functions in humans

scientific article published on 13 August 2016

Mechanisms of natural killer cell-mediated cellular cytotoxicity

scientific article published on 20 May 2019

Modulation of 2B4 (CD244) activity and regulated SAP expression in human NK cells

scientific article published on January 2007

Modulation of NKp30- and NKp46-mediated natural killer cell responses by poxviral hemagglutinin

scientific article

Modulation of natural killer cell functions by interactions between 2B4 and CD48 in cis and in trans

scientific article published on 25 May 2016

Molecular analysis of NTB-A signaling: a role for EAT-2 in NTB-A-mediated activation of human NK cells

scientific article

Molecular basis for positive and negative signaling by the natural killer cell receptor 2B4 (CD244).

scientific article published on 15 February 2005

Molecular mechanisms of natural killer cell regulation.

scientific article published on January 2012

Multiple receptors trigger human NK cell-mediated cytotoxicity against porcine chondrocytes.

scientific article published on 27 January 2012

NAB2 and EGR-1 exert opposite roles in regulating TRAIL expression in human Natural Killer cells.

scientific article published on 14 February 2013

NK Cell Activation

NK cell cytotoxicity mediated by 2B4 and NTB-A is dependent on SAP acting downstream of receptor phosphorylation

scientific article

NK cell detachment from target cells is regulated by successful cytotoxicity and influences cytokine production

scientific article published on 30 August 2019

NK cells switch from granzyme B to death receptor-mediated cytotoxicity during serial killing

scientific article published on 03 July 2019

NK cells--from basic research to cancer therapy

scientific article published on 01 May 2007

NK cells--versatile tools for viral defense and cancer treatment

scientific article published in April 2013

Natural Killer Cells and Liver Fibrosis

scientific article

Natural killer cell inhibitory receptors block actin cytoskeleton-dependent recruitment of 2B4 (CD244) to lipid rafts

scientific article

Natural killer cell regulation - beyond the receptors

scientific article

Natural killer cells: fighting viruses and much more ⬇️

scientific article published on February 1, 2011

Peripheral blood natural killer cell percentages in granulomatosis with polyangiitis correlate with disease inactivity and stage.

scientific article

Production and use of trimeric isoleucine zipper fusion proteins to study surface receptor ligand interactions

scientific article

Protocadherin FAT1 binds Ena/VASP proteins and is necessary for actin dynamics and cell polarization.

scientific article

Protocol for the Optimune trial: a randomized controlled trial evaluating a novel Internet intervention for breast cancer survivors

scientific article published on 29 January 2020

Quantitative analysis of human NK cell reactivity using latex beads coated with defined amounts of antibodies

scientific article published on 06 February 2020

Recruitment of activating NK-cell receptors 2B4 and NKG2D to membrane microdomains in mammalian cells is dependent on their transmembrane regions

scientific article

Regulation of 2B4 (CD244)-mediated NK cell activation by ligand-induced receptor modulation

scientific article published on December 2006

Regulation of NK cell activity by 2B4, NTB-A and CRACC.

scientific article

Regulation of NK cell function by human granulocyte arginase

scientific article published in May 2009

Regulation of natural killer cell activity by glucocorticoids, serotonin, dopamine, and epinephrine

scientific article published on 05 June 2020

Rituximab and Fcγ Receptors in Granulomatosis With Polyangiitis (Wegener's): Comment on the Article by Cartin-Ceba et al

scientific article published on 31 May 2017

Rituximab induces phenotypical and functional changes of NK cells in a non-malignant experimental setting.

scientific article

Robust T cell response towards spike, membrane, and nucleocapsid SARS-CoV-2 proteins is not associated with recovery in critical COVID-19 patients

scientific article published on 29 August 2020

SLAM family receptors in natural killer cells - Mediators of adhesion, activation and inhibition via cis and trans interactions

scientific article published on 22 October 2018

Serial killing of tumor cells by human natural killer cells--enhancement by therapeutic antibodies

scientific article published on 28 March 2007

Signal transduction during activation and inhibition of natural killer cells.

scientific article published on August 2010

Single-Fluorescent Protein Reporters Allow Parallel Quantification of Natural Killer Cell-Mediated Granzyme and Caspase Activities in Single Target Cells

article by Clarissa Liesche et al published 2018 in Frontiers in Immunology

Statins inhibit NK-cell cytotoxicity by interfering with LFA-1-mediated conjugate formation.

scientific article

Surface CD107a/LAMP-1 protects natural killer cells from degranulation-associated damage

scientific article published on 11 July 2013

Synthesis and biological evaluation of 9-N-oxamyl sialosides as Siglec-7 ligands

scientific article published on 07 July 2015

Termination of the Activating NK Cell Immunological Synapse Is an Active and Regulated Process.

scientific article

The NKG2D receptor and its ligands-recognition beyond the "missing self"?

scientific article

The SARS-CoV-2 T-cell immunity is directed against the spike, membrane, and nucleocapsid protein and associated with COVID 19 severity

scientific article published on 17 May 2020

The role of CAP3 in CD95 signaling: new insights into the mechanism of procaspase-8 activation

scientific article published on March 2006

The use of trimeric isoleucine-zipper fusion proteins to study surface-receptor-ligand interactions in natural killer cells

scientific article

Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses

scientific article published on 08 May 2020

Understanding natural killer cell regulation by mathematical approaches

scientific article published on 12 December 2012

Vav1 dephosphorylation by the tyrosine phosphatase SHP-1 as a mechanism for inhibition of cellular cytotoxicity

scientific article published on September 2003

WF10 stimulates NK cell cytotoxicity by increasing LFA-1-mediated adhesion to tumor cells

scientific article published on 3 May 2011

WhatSAP - 2B4 sends mixed messages in the absence of SAP

scientific article published on 14 April 2014

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