List of works - Alexander Visekruna

A key role for NF-κB transcription factor c-Rel in T-lymphocyte-differentiation and effector functions

scientific article

Antigen receptor-mediated depletion of FOXP3 in induced regulatory T-lymphocytes via PTPN2 and FOXO1.

scientific article

Association between activation of atypical NF-kappaB1 p105 signaling pathway and nuclear beta-catenin accumulation in colorectal carcinoma

scientific article

Beyond epithelial to mesenchymal transition: a novel role for the transcription factor Snail in inflammation and wound healing

scientific article published on 24 October 2009

Comparative expression analysis and characterization of 20S proteasomes in human intestinal tissues: The proteasome pattern as diagnostic tool for IBD patients.

scientific article published in April 2009

Expression of catalytic proteasome subunits in the gut of patients with Crohn's disease

scientific article published on 10 March 2009

Functional heterogeneity of gut-resident regulatory T cells

scientific article published on 22 September 2017

Genetic and pharmacological targeting of TPL-2 kinase ameliorates experimental colitis: a potential target for the treatment of Crohn's disease?

scientific article published on 7 December 2011

Heterogeneity in the differentiation and function of CD8⁺ T cells

scientific article published on 31 May 2014

IKK-induced NF-κB1 p105 proteolysis is critical for B cell antibody responses to T cell-dependent antigen

scientific article

IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis

scientific article published on 10 December 2012

Immunoproteasomes are essential for clearance of Listeria monocytogenes in nonlymphoid tissues but not for induction of bacteria-specific CD8+ T cells

scientific article published on 01 November 2006

Lack of microbiota reduces innate responses and enhances adaptive immunity against Listeria monocytogenes infection

scientific article

Leprosy susceptibility-a matter of protein degradation? The role of proteasomes in infection and disease.

scientific article published in June 2005

NALP expression in Paneth cells provides a novel track in IBD signaling.

scientific article published on 24 March 2010

Prevention of colitis-associated cancer by selective targeting of immunoproteasome subunit LMP7.

scientific article published on 10 January 2017

Proteasome-mediated degradation of IkappaBalpha and processing of p105 in Crohn disease and ulcerative colitis

scientific article

Regulation of the effector function of CD8 T cells by gut microbiota-derived metabolite butyrate

scientific article published in Scientific Reports

Short-chain fatty acids: Bacterial messengers modulating the immunometabolism of T cells

scientific article published on 17 May 2019

Targeting the proteasome: partial inhibition of the proteasome by bortezomib or deletion of the immunosubunit LMP7 attenuates experimental colitis

scientific article published in July 2010

Tc9 cells, a new subset of CD8(+) T cells, support Th2-mediated airway inflammation

scientific article published on 31 January 2013

The NF-κB transcription factor c-Rel controls host defense against Citrobacter rodentium

scientific article published on 25 November 2019

The proteasome system in infection: impact of β5 and LMP7 on composition, maturation and quantity of active proteasome complexes

scientific article

The role of NF-κB activation during protection against Leishmania infection.

scientific article published on 14 August 2012

The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes

scientific article published in Nature Communications

Transcription factor c-Rel is indispensable for generation of thymic but not of peripheral Foxp3+ regulatory T cells

scientific article published on 13 April 2017

Transcription factor c-Rel plays a crucial role in driving anti-CD40-mediated innate colitis.

scientific article published on 6 August 2014

c-REL and IκBNS Govern Common and Independent Steps of Regulatory T Cell Development from Novel CD122-Expressing Pre-Precursors.

scientific article published on 26 June 2017

c-Rel is crucial for the induction of Foxp3(+) regulatory CD4(+) T cells but not T(H)17 cells.

scientific article published in March 2010

c-Rel promotes type 1 and type 17 immune responses during Leishmania major infection

scientific article published on 11 April 2011

rKLO8, a novel Leishmania donovani - derived recombinant immunodominant protein for sensitive detection of visceral leishmaniasis in Sudan

scientific article

List of works by Alexander Visekruna

A key role for NF-κB transcription factor c-Rel in T-lymphocyte-differentiation and effector functions

Antigen receptor-mediated depletion of FOXP3 in induced regulatory T-lymphocytes via PTPN2 and FOXO1.

Association between activation of atypical NF-kappaB1 p105 signaling pathway and nuclear beta-catenin accumulation in colorectal carcinoma

Beyond epithelial to mesenchymal transition: a novel role for the transcription factor Snail in inflammation and wound healing

Comparative expression analysis and characterization of 20S proteasomes in human intestinal tissues: The proteasome pattern as diagnostic tool for IBD patients.

Expression of catalytic proteasome subunits in the gut of patients with Crohn's disease

Functional heterogeneity of gut-resident regulatory T cells

Genetic and pharmacological targeting of TPL-2 kinase ameliorates experimental colitis: a potential target for the treatment of Crohn's disease?

Heterogeneity in the differentiation and function of CD8⁺ T cells

IKK-induced NF-κB1 p105 proteolysis is critical for B cell antibody responses to T cell-dependent antigen

IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis

Immunoproteasomes are essential for clearance of Listeria monocytogenes in nonlymphoid tissues but not for induction of bacteria-specific CD8+ T cells

Lack of microbiota reduces innate responses and enhances adaptive immunity against Listeria monocytogenes infection

Leprosy susceptibility-a matter of protein degradation? The role of proteasomes in infection and disease.

NALP expression in Paneth cells provides a novel track in IBD signaling.

Prevention of colitis-associated cancer by selective targeting of immunoproteasome subunit LMP7.

Proteasome-mediated degradation of IkappaBalpha and processing of p105 in Crohn disease and ulcerative colitis

Regulation of the effector function of CD8 T cells by gut microbiota-derived metabolite butyrate

Short-chain fatty acids: Bacterial messengers modulating the immunometabolism of T cells

Targeting the proteasome: partial inhibition of the proteasome by bortezomib or deletion of the immunosubunit LMP7 attenuates experimental colitis

Tc9 cells, a new subset of CD8(+) T cells, support Th2-mediated airway inflammation

The NF-κB transcription factor c-Rel controls host defense against Citrobacter rodentium

The proteasome system in infection: impact of β5 and LMP7 on composition, maturation and quantity of active proteasome complexes

The role of NF-κB activation during protection against Leishmania infection.

The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes

Transcription factor c-Rel is indispensable for generation of thymic but not of peripheral Foxp3+ regulatory T cells

Transcription factor c-Rel plays a crucial role in driving anti-CD40-mediated innate colitis.

c-REL and IκBNS Govern Common and Independent Steps of Regulatory T Cell Development from Novel CD122-Expressing Pre-Precursors.

c-Rel is crucial for the induction of Foxp3(+) regulatory CD4(+) T cells but not T(H)17 cells.

c-Rel promotes type 1 and type 17 immune responses during Leishmania major infection

rKLO8, a novel Leishmania donovani - derived recombinant immunodominant protein for sensitive detection of visceral leishmaniasis in Sudan