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List of works by Amedeo De Nicolò

A LC-MS method to quantify tenofovir urinary concentrations in treated patients.

scientific article

A Possible Role of Therapeutic Drug Monitoring in Virological Breakthrough during Simeprevir and PEG-IFN Treatment in HCV-4.

scientific article published on 22 June 2017

A UHPLC-MS/MS method for the quantification of direct antiviral agents simeprevir, daclatasvir, ledipasvir, sofosbuvir/GS-331007, dasabuvir, ombitasvir and paritaprevir, together with ritonavir, in human plasma

scientific article published on 20 April 2016

A UPLC-MS/MS method for the simultaneous plasma quantification of all isomeric forms of the new anti-HCV protease inhibitors boceprevir and telaprevir

scientific article published on 27 February 2013

A simple UHPLC-PDA method with a fast dilute-and-shot sample preparation for the quantification of canrenone and its prodrug spironolactone in human urine samples

scientific article published on 28 August 2018

ABCB11 and ABCB1 gene polymorphisms impact on telaprevir pharmacokinetic at one month of therapy

scientific article published on 15 November 2014

An UPLC-MS/MS method coupled with automated on-line SPE for quantification of tacrolimus in peripheral blood mononuclear cells.

scientific article published on 7 February 2015

Antihypertensive Bridge Therapy by Continuous Drug Infusion With an Elastomeric Pump in Device-Resistant Hypertension.

scientific article

Association of ITPA polymorphisms rs6051702/rs1127354 instead of rs7270101/rs1127354 as predictor of ribavirin-associated anemia in chronic hepatitis C treated patients.

scientific article published on 8 August 2013

Association of vitamin D pathway SNPs and clinical response to interferon in a cohort of HBeAg-negative patients

scientific article published on 28 April 2017

Development and validation of a useful HPLC-UV method for quantification of total and phosphorylated-ribavirin in blood and erythrocytes of HCV+ patients

scientific article published on 28 March 2012

Development and validation of a useful UPLC-MS/MS method for quantification of total and phosphorylated-ribavirin in peripheral blood mononuclear cells of HCV+ patients.

scientific article published on December 2013

Different HBsAg decline after 3 years of therapy with entecavir in patients affected by chronic hepatitis B HBeAg-negative and genotype A, D and E.

scientific article published on 8 August 2014

Efficacy of sofosbuvir and ledipasvir in an HCV+ gastro-resected patient.

scientific article published on 4 May 2017

Entecavir plasma concentrations are inversely related to HBV-DNA decrease in a cohort of treatment-naïve patients with chronic hepatitis B.

scientific article published on 7 July 2016

First UHPLC-MS/MS method coupled with automated online SPE for quantification both of tacrolimus and everolimus in peripheral blood mononuclear cells and its application on samples from co-treated pediatric patients

scientific article published on 18 January 2017

Identification of naïve HVC-4 patients who may be treated with pegylated-interferon and ribavirin according to IL28B polymorphisms.

scientific article published on 12 April 2014

Intracellular accumulation of boceprevir according to plasma concentrations and pharmacogenetics.

scientific article published on 14 March 2015

Intracellular antiviral activity of low-dose ritonavir in boosted protease inhibitor regimens

scientific article

LC-MS application for therapeutic drug monitoring in alternative matrices

scientific article published on 29 December 2018

No pharmacokinetic interaction between raltegravir and amlodipine: importance for co-prescribing in ageing HIV-infected individuals

scientific article published on 01 August 2014

Pharmacogenetic analysis of hepatitis C virus related mixed cryoglobulinemia.

scientific article published on 28 April 2017

Pharmacogenetics of ribavirin-induced anemia in HCV patients

scientific article published on June 2016

Relationship between the early boceprevir-S isomer plasma concentrations and the onset of breakthrough during HCV genotype 1 triple therapy

scientific article published on 29 October 2014

Role of CYP27B1+2838 promoter polymorphism in the treatment of chronic hepatitis B HBeAg negative with PEG-interferon.

scientific article published on 24 July 2014

Role of pharmacogenetic in ribavirin outcome prediction and pharmacokinetics in an Italian cohort of HCV-1 and 4 patients

scientific article published on 6 November 2014

Role of simeprevir plasma concentrations in HCV treated patients with dermatological manifestations

scientific article published on 17 January 2017

SLC29A1 polymorphism and prediction of anaemia severity in patients with chronic hepatitis C receiving triple therapy with telaprevir

scientific article

Sequential therapy with entecavir and PEG-INF in patients affected by chronic hepatitis B and high levels of HBV-DNA with non-D genotypes

scientific article published on 18 February 2013

Significant early higher ribavirin plasma concentrations in patients receiving a triple therapy with pegylated interferon, ribavirin and telaprevir

scientific article published on 2 September 2013

Telaprevir-S isomer enhances ribavirin exposure and the ribavirin-related haemolytic anaemia in a concentration-dependent manner.

scientific article published on 20 June 2014

Treatment with PEG-IFN and ribavirin in patients with chronic hepatitis C, low grade of hepatic fibrosis, genotype 1 and 4 and favorable IFNL3 genotype: A pharmacogenetic prospective study

scientific article published on 15 March 2017

Treatment with daclatasvir and sofosbuvir for 24 weeks without ribavirin in cirrhotic patients who failed first-generation protease inhibitors.

scientific article

Treatment with direct-acting antiviral agents of hepatitis C virus infection in injecting drug users: A prospective study.

scientific article published on 26 March 2017

Triple or dual therapy for HCV-1 naive patients? Optimizing selection tools

scientific article published on 21 March 2014

UHPLC-MS/MS method with automated on-line solid phase extraction for the quantification of entecavir in peripheral blood mononuclear cells of HBV+ patients.

scientific article published on 22 October 2015

UHPLC-MS/MS method with protein precipitation extraction for the simultaneous quantification of ten antihypertensive drugs in human plasma from resistant hypertensive patients

scientific article published on August 2016

UHPLC-MS/MS method with sample dilution to test therapeutic adherence through quantification of ten antihypertensive drugs in urine samples

scientific article published on 13 May 2017

UPLC-MS/MS method for quantification of the azathioprine metabolites 6-mercaptoguanosine and 6-methylmercaptopurine riboside in peripheral blood mononuclear cells

scientific article published on 7 June 2014

UPLC-MS/MS method for the simultaneous quantification of anti-HBV nucleos(t)ides analogs: Entecavir, lamivudine, telbivudine and tenofovir in plasma of HBV infected patients

scientific article published on 22 May 2015

UPLC-MS/MS method for the simultaneous quantification of three new antiretroviral drugs, dolutegravir, elvitegravir and rilpivirine, and other thirteen antiretroviral agents plus cobicistat and ritonavir boosters in human plasma

scientific article published on 3 February 2017

UPLC-MS/MS method with automated on-line SPE for the isomer-specific quantification of the first-generation anti-HCV protease inhibitors in peripheral blood mononuclear cells.

scientific article

VDR gene polymorphisms impact on anemia at 2 weeks of anti-HCV therapy: a possible mechanism for early RBV-induced anemia.

scientific article published on April 2015

Validation of a UHPLC-MS/MS Method to Quantify Twelve Antiretroviral Drugs within Peripheral Blood Mononuclear Cells from People Living with HIV

scientific article published on 25 December 2020

Vitamin D pathway gene polymorphisms as predictors of hepatitis C virus-related mixed cryoglobulinemia

scientific article published on June 2016

Vitamin D pathway gene variants and HCV-2/3 therapy outcomes

scientific article published on 3 October 2014

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