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List of works by Marco Donia

"Immunotherapy of cancer: present status and future promise": Danish Cancer Society Symposium, Copenhagen, Denmark, 23rd-25th September 2013.

scientific article published on 24 July 2014

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

A phase 1/2 trial of an immune-modulatory vaccine against IDO/PD-L1 in combination with nivolumab in metastatic melanoma

scientific article published on 09 December 2021

Aberrant Expression of MHC Class II in Melanoma Attracts Inflammatory Tumor-Specific CD4 + T- Cells, Which Dampen CD8 + T-cell Antitumor Reactivity

scientific article (publication date: 16 July 2015)

Acquired Immune Resistance Follows Complete Tumor Regression without Loss of Target Antigens or IFNγ Signaling.

scientific article

Acquired resistance to cancer immunotherapy

scientific article published on 02 July 2018

Adoptive cell therapy with autologous tumor infiltrating lymphocytes and low-dose Interleukin-2 in metastatic melanoma patients

scientific article

Adoptive cell therapy with tumor infiltrating lymphocytes and intermediate dose IL-2 for metastatic melanoma

Adoptive cell therapy with tumor-infiltrating lymphocytes in patients with metastatic ovarian cancer: a pilot study

scientific article published on 26 September 2018

Adoptive cell therapy with tumor-infiltrating lymphocytes supported by checkpoint inhibition across multiple solid cancer types

scientific article published in October 2021

Advances in targeting signal transduction pathways

scientific article

Analysis of Vδ1 T cells in clinical grade melanoma-infiltrating lymphocytes

scientific article published on November 2012

Analysis of interleukin (IL)-1beta IL-1 receptor antagonist, soluble IL-1 receptor type II and IL-1 accessory protein in HCV-associated lymphoproliferative disorders.

scientific article

Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRs

scientific article

Author Correction: Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1

scientific article published on 02 March 2020

BRAF inhibition improves tumor recognition by the immune system: Potential implications for combinatorial therapies against melanoma involving adoptive T-cell transfer

scientific article published on December 2012

Biological insights into BRAF(V600) mutations in melanoma patient: Not mere therapeutic targets

scientific article published on 3 July 2013

Breast cancer: Molecular basis and therapeutic strategies (Review).

scientific article published on July 2008

Broadening the repertoire of melanoma-associated T-cell epitopes.

scientific article published on 18 February 2015

CCL22-specific T Cells: Modulating the immunosuppressive tumor microenvironment.

scientific article published on 30 September 2016

CTLA-4 blockade boosts the expansion of tumor-reactive CD8+ tumor-infiltrating lymphocytes in ovarian cancer

scientific article published on 03 March 2020

Cancer immunotherapy in patients with brain metastases.

scientific article published on 8 March 2018

Cancer immunotherapy in patients with preexisting autoimmune disorders

scientific article

Changes in the Tumor Immune Microenvironment during Disease Progression in Patients with Ovarian Cancer

scientific article published on 18 December 2020

Characterization and comparison of 'standard' and 'young' tumour-infiltrating lymphocytes for adoptive cell therapy at a Danish translational research institution.

scientific article published in February 2012

Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model

scientific article published on 27 September 2017

Coexisting Alterations of MHC Class I Antigen Presentation and IFNγ Signaling Mediate Acquired Resistance of Melanoma to Post–PD-1 Immunotherapy

scientific article published on 15 August 2022

Collagen density regulates the activity of tumor-infiltrating T cells

scientific article published on 12 March 2019

Comparative study of rapamycin and temsirolimus demonstrates superimposable anti-tumour potency on prostate cancer cells.

scientific article

Comparison of clinical grade type 1 polarized and standard matured dendritic cells for cancer immunotherapy

scientific article published on 29 November 2012

Correction: Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma

Correction: Tumour-reactive T cell subsets in the microenvironment of ovarian cancer

scientific article published on 01 April 2019

Cytotoxic and immune-sensitizing properties of nitric oxide-modified Saquinavir in iNOS-positive human melanoma cells.

scientific article

Data from Uncoupling CD4<sup>+</sup> TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma

scientific article published on 2 October 2023

Data from Uncoupling CD4<sup>+</sup> TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma

scientific article published on 12 May 2023

Development of anti-drug antibodies is associated with shortened survival in patients with metastatic melanoma treated with ipilimumab.

scientific article published in February 2018

Differential effects of corticosteroids and anti-TNF on tumor-specific immune responses - implications for the management of irAEs

scientific article published on 8 October 2018

Differential effects of corticosteroids and anti-TNF on tumor-specific immune responses: implications for the management of irAEs

scientific article published on 07 January 2019

Dissection of T-cell Antigen Specificity in Human Melanoma

scientific article published on 06 February 2012

Dominant roles of the Raf/MEK/ERK pathway in cell cycle progression, prevention of apoptosis and sensitivity to chemotherapeutic drugs

scientific article published on 15 April 2010

Effector CD4 and CD8 T cells and their role in the tumor microenvironment

scientific article published on 16 December 2012

Effects of Ipilimumab on expanded tumor infiltrating lymphocytes in patients with stage IV malignant melanoma

scientific article published on 7 November 2013

Efficacy of Intracolonic Administration of Low-Molecular-Weight Heparin CB-01-05, Compared to Other Low-Molecular-Weight Heparins and Unfractionated Heparin, in Experimentally Induced Colitis in Rat

Efficacy of intracolonic administration of low-molecular-weight heparin CB-01-05, compared to other low-molecular-weight heparins and unfractionated heparin, in experimentally induced colitis in rat.

scientific article published on 9 May 2008

Eleventh international conference on progress in vaccination against cancer (PIVAC-11), 10-13 October 2011, Copenhagen, Denmark

scientific article published on 5 February 2012

Empty peptide-receptive MHC class I molecules for efficient detection of antigen-specific T cells

scientific article published on 01 July 2019

Enhancing therapeutic efficacy by targeting non-oncogene addicted cells with combinations of signal transduction inhibitors and chemotherapy

scientific article published on 15 May 2010

Frequent adaptive immune responses against arginase-1.

scientific article published on 26 December 2017

Generation of autologous tumor-specific T cells for adoptive transfer based on vaccination, in vitro restimulation and CD3/CD28 dynabead-induced T cell expansion

scientific article published on 12 January 2012

Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1

scientific article published on 20 January 2020

HER2 CAR-T Cells Eradicate Uveal Melanoma and T-cell Therapy-Resistant Human Melanoma in IL2 Transgenic NOD/SCID IL2 Receptor Knockout Mice

scientific article published on 08 January 2019

HLA-Restricted CTL That Are Specific for the Immune Checkpoint Ligand PD-L1 Occur with High Frequency in Cancer Patients

scientific article published on 17 January 2013

Highly efficient PD-1-targeted CRISPR-Cas9 for tumor-infiltrating lymphocyte-based adoptive T cell therapy

scientific article published on 10 January 2022

In vitro and in vivo anticancer action of Saquinavir-NO, a novel nitric oxide-derivative of the protease inhibitor saquinavir, on hormone resistant prostate cancer cells.

scientific article published on February 2011

In vitro inhibition of enterobacteria-reactive CD4+CD25- T cells and suppression of immunoinflammatory colitis in mice by the novel immunomodulatory agent VGX-1027.

scientific article published on 17 February 2008

In vitro, ex vivo and in vivo immunopharmacological activities of the isoxazoline compound VGX-1027: Modulation of cytokine synthesis and prevention of both organ-specific and systemic autoimmune diseases in murine models

article

Induction of caspase-independent apoptotic-like cell death of mouse mammary tumor TA3Ha cells in vitro and reduction of their lethality in vivo by the novel chemotherapeutic agent GIT-27NO.

scientific article

Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma.

scientific article

Influence of mutagenic versus non-mutagenic pre-operative chemotherapy on the immune infiltration of residual breast cancer

scientific article published on 04 July 2019

Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes.

scientific article published on 29 August 2016

Long-Lasting Complete Responses in Patients with Metastatic Melanoma after Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes and an Attenuated IL2 Regimen.

scientific article published on 22 March 2016

Long-Term Vemurafenib Exposure Induced Alterations of Cell Phenotypes in Melanoma: Increased Cell Migration and Its Association with EGFR Expression

scientific article published on 11 September 2019

Loss of Ambra1 promotes melanoma growth and invasion

scientific article published on 05 May 2021

MERTK Acts as a Costimulatory Receptor on Human CD8+ T Cells

scientific article published on 02 July 2019

Methods to improve adoptive T-cell therapy for melanoma: IFN-γ enhances anticancer responses of cell products for infusion

scientific article

More tricks with tetramers: a practical guide to staining T cells with peptide-MHC multimers

scientific article

Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma

scientific article published on 23 November 2017

Natural CD4+ T-cell responses against indoleamine 2,3-dioxygenase

scientific article (publication date: 2012)

New developments in the management of advanced melanoma - role of pembrolizumab

scientific article

New perspectives in HCV therapy: entry inhibitors.

scientific article

Novel nitric oxide-donating compound (S,R)-3-phenyl-4,5-dihydro-5-isoxazole acetic acid-nitric oxide (GIT-27NO) induces p53 mediated apoptosis in human A375 melanoma cells.

scientific article

PD-1+ Polyfunctional T Cells Dominate the Periphery after Tumor-Infiltrating Lymphocyte Therapy for Cancer

scientific article published on 5 July 2017

PD-L1 peptide co-stimulation increases immunogenicity of a dendritic cell-based cancer vaccine.

scientific article published on July 2016

Peptide Super-Agonist Enhances T-Cell Responses to Melanoma

article

Peptide-MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations.

scientific article published on 26 February 2018

Personalized therapy with peptide-based neoantigen vaccine (EVX-01) including a novel adjuvant, CAF®09b, in patients with metastatic melanoma

scientific article published on 10 January 2022

Phase 2 study of ipilimumab, nivolumab, and tocilizumab combined with stereotactic body radiotherapy in patients with refractory pancreatic cancer (TRIPLE-R)

scientific article published in February 2023

Phase II study of the antiretroviral activity and safety of the glucocorticoid receptor antagonist mifepristone in HIV-1-infected patients

article

Polyfunctional incompletely differentiated CD8+ T cells accumulates after adoptive transfer of tumor-infiltrating lymphocytes and establish immunological memory in patients with metastatic melanoma.

scientific article published on 4 November 2015

Potential use of rapamycin in HIV infection

scientific article

Principles of adoptive T cell therapy in cancer

scientific article published on 05 September 2018

Qualitative Analysis of Tumor-Infiltrating Lymphocytes across Human Tumor Types Reveals a Higher Proportion of Bystander CD8+ T Cells in Non-Melanoma Cancers Compared to Melanoma

scientific article published on 12 November 2020

Rapid Identification of the Tumor-Specific Reactive TIL Repertoire Combined Detection of CD137, TNF, and IFNγ, Following Recognition of Autologous Tumor-Antigens

scientific article published in 2021

Rare cause of spontaneous haemothorax: mediastinal and distant lymph node metastases from uveal melanoma

scientific article published on 21 November 2019

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health

scientific article published on March 2011

Real-World Impact of Immune Checkpoint Inhibitors in Metastatic Uveal Melanoma

scientific article published on 03 October 2019

Real-world evidence to guide healthcare policies in oncology

scientific article published on 16 July 2019

Reorienting the immune system in the treatment of cancer by using anti-PD-1 and anti-PD-L1 antibodies.

scientific article published on 16 July 2015

Role of signal transduction and microRNAs on the immunogenicity of melanoma cells

scientific article

Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging

scientific article

Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy.

scientific article published on 15 April 2011

S76. Adoptive cell therapy of melanoma with autologous tumour infiltrating lymphocytes

Simplified protocol for clinical-grade tumor-infiltrating lymphocyte manufacturing with use of the Wave bioreactor

scientific article published on 13 May 2014

Specific and strain-independent effects of dexamethasone in the prevention and treatment of experimental autoimmune encephalomyelitis in rodents

scientific article

Supplementary Data 1 from Uncoupling CD4<sup>+</sup> TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma

Supplementary Data 1 from Uncoupling CD4<sup>+</sup> TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma

scientific article published on 2 October 2023

Supplementary Data 1 from Uncoupling CD4<sup>+</sup> TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma

Supplementary Data 1 from Uncoupling CD4<sup>+</sup> TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma

scientific article published on 12 May 2023

Supplementary Data 2 from Uncoupling CD4<sup>+</sup> TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma

Supplementary Data 2 from Uncoupling CD4<sup>+</sup> TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma

scientific article published on 2 October 2023

Supplementary Data 2 from Uncoupling CD4<sup>+</sup> TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma

Supplementary Data 2 from Uncoupling CD4<sup>+</sup> TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma

scientific article published on 12 May 2023

Supplementary Data 3 from Uncoupling CD4<sup>+</sup> TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma

Supplementary Data 3 from Uncoupling CD4<sup>+</sup> TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma

scientific article published on 2 October 2023

Supplementary Data 3 from Uncoupling CD4<sup>+</sup> TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma

scientific article published on 12 May 2023

Supplementary Data 3 from Uncoupling CD4<sup>+</sup> TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma

Supplementary Material 1 from Uncoupling CD4<sup>+</sup> TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma

scientific article published on 2 October 2023

Supplementary Material 1 from Uncoupling CD4<sup>+</sup> TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma

Supplementary Material 1 from Uncoupling CD4<sup>+</sup> TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma

scientific article published on 12 May 2023

Supplementary Material 1 from Uncoupling CD4<sup>+</sup> TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma

T cell therapy in combination with Vemurafenib in BRAF mutated metastatic melanoma patients.

scientific article published on 6 November 2014

T cells isolated from patients with checkpoint inhibitor resistant-melanoma are functional and can mediate tumor regression.

scientific article published on 24 April 2018

T-cell Responses in the Microenvironment of Primary Renal Cell Carcinoma-Implications for Adoptive Cell Therapy.

scientific article published on 4 January 2018

Targeting of cancer neoantigens with donor-derived T cell receptor repertoires

scientific article

Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway

scientific article

Tertiary lymphoid structures improve immunotherapy and survival in melanoma

scientific article published on 15 January 2020

The Raf/MEK/ERK pathway can govern drug resistance, apoptosis and sensitivity to targeted therapy

scientific article published on 10 May 2010

The controversial role of TNF in melanoma

scientific article

The effects of targeted immune-regulatory strategies on tumor-specific T-cell responses in vitro

scientific article published on 09 November 2020

The inhibitory checkpoint, PD-L2, is a target for effector T cells: Novel possibilities for immune therapy.

scientific article published in November 2017

The majority of patients with metastatic melanoma are not represented in pivotal phase III immunotherapy trials.

scientific article published on 12 February 2017

The novel NO-donating compound GIT-27NO inhibits in vivo growth of human prostate cancer cells and prevents murine immunoinflammatory hepatitis

scientific article

The real-world impact of modern treatments on the survival of patients with metastatic melanoma

scientific article published on 31 December 2018

The real-world outcome of metastatic melanoma: Unknown primary vs. known cutaneous

scientific article published on 03 September 2019

Therapeutic potential of nitric oxide-modified drugs in colon cancer cells

scientific article

Transcriptomic signatures of tumors undergoing T cell attack

scientific article published on 17 July 2021

Treatment with rapamycin ameliorates clinical and histological signs of protracted relapsing experimental allergic encephalomyelitis in Dark Agouti rats and induces expansion of peripheral CD4+CD25+Foxp3+ regulatory T cells.

scientific article published on 21 July 2009

Tumor infiltrating lymphocyte therapy for ovarian cancer and renal cell carcinoma.

scientific article published on 26 August 2015

Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma

scientific article published on 8 December 2022

Tumor-induced escape mechanisms and their association with resistance to checkpoint inhibitor therapy

scientific article published on 03 August 2019

Tumor-infiltrating lymphocytes for adoptive cell therapy: recent advances, challenges, and future directions

scientific article published in 2022

Tumor-infiltrating lymphocytes for the treatment of metastatic cancer.

scientific article published on 30 October 2015

Tumour-reactive T cell subsets in the microenvironment of ovarian cancer

scientific article published on 05 February 2019

Uncoupling CD4+ TIL-Mediated Tumor Killing from JAK-Signaling in Melanoma

scientific article published in May 2023

Unique antineoplastic profile of Saquinavir-NO, a novel NO-derivative of the protease inhibitor Saquinavir, on the in vitro and in vivo tumor formation of A375 human melanoma cells

scientific article

Variable effects of cyclophosphamide in rodent models of experimental allergic encephalomyelitis

scientific article published on 18 November 2009

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