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List of works by Holger Martin Koch

A critical evaluation of the creatinine correction approach: can it underestimate intakes of phthalates? A case study with di-2-ethylhexyl phthalate

scientific article published on 8 September 2010

A pilot study on the feasibility of European harmonized human biomonitoring: Strategies towards a common approach, challenges and opportunities.

scientific article

A population-based case-control study of urinary bisphenol A concentrations and risk of endometriosis.

scientific article

A simple pharmacokinetic model to characterize exposure of Americans to di-2-ethylhexyl phthalate

scientific article

A systematic approach for designing a HBM pilot study for Europe

scientific article published on 8 July 2013

Additional oxidized and alkyl chain breakdown metabolites of the plasticizer DINCH in urine after oral dosage to human volunteers.

scientific article

An eco-friendly sample preparation procedure based on air-assisted liquid-liquid microextraction for the rapid determination of phthalate metabolites in urine samples by liquid chromatography-tandem mass spectrometry

An estimation of the daily intake of di(2-ethylhexyl)phthalate (DEHP) and other phthalates in the general population

scientific article published in March 2003

Analysis of ethenoguanine adducts in human urine using high performance liquid chromatography-tandem mass spectrometry

scientific article published in August 2002

Analyzing terephthalate metabolites in human urine as biomarkers of exposure: Importance of selection of metabolites and deconjugation enzyme

scientific article published on 02 October 2018

Aniline Is Rapidly Converted Into Paracetamol Impairing Male Reproductive Development.

scientific article published on 10 August 2015

Assessing exposure to phthalates - the human biomonitoring approach.

scientific article published on January 2011

Assessing human exposure to organic pollutants in the indoor environment

scientific article published on 14 March 2018

Assessment of phthalates/phthalate alternatives in children's toys and childcare articles: Review of the report including conclusions and recommendation of the Chronic Hazard Advisory Panel of the Consumer Product Safety Commission.

scientific article published on 06 May 2015

Associations between urinary organophosphate pesticide metabolite levels and reproductive parameters in men from an infertility clinic.

scientific article published on 16 January 2015

BPA and risk assessment

scientific article published on 01 April 2020

Biological monitoring of the five major metabolites of di-(2-ethylhexyl)phthalate (DEHP) in human urine using column-switching liquid chromatography-tandem mass spectrometry

scientific article published in February 2005

Biomonitoring of N-ethyl-2-pyrrolidone in automobile varnishers.

scientific article published on 17 October 2014

Biomonitoring of exposure to N-methyl-2-pyrrolidone in workers of the automobile industry.

scientific article published on 20 January 2013

Bis-(2-propylheptyl)phthalate (DPHP) metabolites emerging in 24h urine samples from the German Environmental Specimen Bank (1999-2012).

scientific article

Bisphenol A in 24 h urine and plasma samples of the German Environmental Specimen Bank from 1995 to 2009: a retrospective exposure evaluation

scientific article

Case study: Possible differences in phthalates exposure among the Czech, Hungarian, and Slovak populations identified based on the DEMOCOPHES pilot study results

scientific article published on December 2014

Changes in urinary excretion of phthalates, phthalate substitutes, bisphenols and other polychlorinated and phenolic substances in young Danish men; 2009-2017

scientific article published on 25 October 2019

Comment on "Urinary Metabolites of Neonicotinoid Insecticides: Levels and Recommendations for Future Biomonitoring Studies in China": Quantification of 5-Hydroxyimidacloprid and Biomonitoring

scientific article published on 08 January 2021

Communication in a Human biomonitoring study: Focus group work, public engagement and lessons learnt in 17 European countries

scientific article published on 11 December 2014

Correction to: Metabolites of the alkyl pyrrolidone solvents NMP and NEP in 24-h urine samples of the German Environmental Specimen Bank from 1991 to 2014

scientific article published on 01 January 2020

DEHP deregulates adipokine levels and impairs fatty acid storage in human SGBS-adipocytes

scientific article published on 22 February 2018

DEHP metabolites in urine of children and DEHP in house dust

scientific article published in October 2004

Daily intake and hazard index of parabens based upon 24 h urine samples of the German Environmental Specimen Bank from 1995 to 2012.

scientific article

Daily intake of di(2-ethylhexyl)phthalate (DEHP) by German children -- A comparison of two estimation models based on urinary DEHP metabolite levels

scientific article published on 20 December 2006

De-novo identification of specific exposure biomarkers of the alternative plasticizer di(2-ethylhexyl) terephthalate (DEHTP) after low oral dosage to male volunteers by HPLC-Q-Orbitrap-MS.

scientific article published on 28 November 2017

Dermal uptake of nicotine from air and clothing: Experimental verification

scientific article

Determinants of phthalate exposure and risk assessment in children from Poland

scientific article published on 16 April 2019

Determination of 2,3-dihydroxypropionamide, an oxidative metabolite of acrylamide, in human urine by gas chromatography coupled with mass spectrometry

scientific article published on 26 January 2012

Determination of Urinary Metabolites of the Emerging UV Filter Octocrylene by Online-SPE-LC-MS/MS.

scientific article published on 30 November 2017

Determination of bisphenol a in urine from mother-child pairs-results from the duisburg birth cohort study, Germany

scientific article published on 01 January 2012

Determination of di-n-butyl adipate (DnBA) metabolites as possible biomarkers of exposure in human urine by online-SPE-LC-MS/MS

scientific article published on 13 February 2020

Determination of human urinary metabolites of the plasticizer di(2-ethylhexyl) adipate (DEHA) by online-SPE-HPLC-MS/MS

scientific article published on 17 June 2019

Determination of metabolites of di(2-ethylhexyl) terephthalate (DEHTP) in human urine by HPLC-MS/MS with on-line clean-up

scientific article published on 24 December 2015

Determination of metabolites of the UV filter 2-ethylhexyl salicylate in human urine by online-SPE-LC-MS/MS

scientific article published on 14 February 2019

Determination of secondary, oxidised di-iso-nonylphthalate (DINP) metabolites in human urine representative for the exposure to commercial DINP plasticizers

scientific article published on 20 October 2006

Development and application of simple pharmacokinetic models to study human exposure to di-n-butyl phthalate (DnBP) and diisobutyl phthalate (DiBP)

scientific article published on 15 August 2013

Development of a multi-compartment pharmacokinetic model to characterize the exposure to Hexamoll® DINCH®.

scientific article published on 21 February 2015

Di(2-ethylhexyl)phthalate (DEHP) exposure of voluntary plasma and platelet donors.

scientific article

Di(2-ethylhexyl)phthalate (DEHP) metabolites in human urine and serum after a single oral dose of deuterium-labelled DEHP.

scientific article published on 24 October 2003

Di(2-ethylhexyl)phthalate exposure of apheresis donors is procedure-related

scientific article published in August 2006

Di-iso-nonylphthalate (DINP) metabolites in human urine after a single oral dose of deuterium-labelled DINP

scientific article published on 19 December 2006

Di-n-butyl phthalate (DnBP) and diisobutyl phthalate (DiBP) metabolism in a human volunteer after single oral doses

scientific article published on 22 July 2012

Di-n-butylphthalate and butylbenzylphthalate - urinary metabolite levels and estimated daily intakes: pilot study for the German Environmental Survey on children

scientific article published on 27 September 2006

Dietary and sociodemographic determinants of bisphenol A urine concentrations in pregnant women and children

scientific article published on 26 March 2013

Effects of the environmental contaminants DEHP and TCDD on estradiol synthesis and aryl hydrocarbon receptor and peroxisome proliferator-activated receptor signalling in the human granulosa cell line KGN.

scientific article

Endocrine disrupting chemicals affect the adipogenic differentiation of mesenchymal stem cells in distinct ontogenetic windows ⬇️

scientific article published on December 16, 2011

Entering markets and bodies: increasing levels of the novel plasticizer Hexamoll® DINCH® in 24 h urine samples from the German Environmental Specimen Bank

scientific article

Erfassung der Humanexposition mit organischen Verbindungen in Innenraumumgebungen

European interlaboratory comparison investigations (ICI) and external quality assurance schemes (EQUAS) for the analysis of bisphenol A, S and F in human urine: Results from the HBM4EU project

scientific article published on 17 February 2022

Evaluation of exposure to phthalate esters and DINCH in urine and nails from a Norwegian study population

scientific article

Excretion of 2,3-dihydroxy-propionamide (OH-PA), the hydrolysis product of glycidamide, in human urine after single oral dose of deuterium-labeled acrylamide

scientific article published on 15 October 2010

Exposure assessment to bisphenol A (BPA) in Portuguese children by human biomonitoring.

scientific article

Exposure determinants of cadmium in European mothers and their children

scientific article published on 20 November 2014

Exposure of Portuguese children to the novel non-phthalate plasticizer di-(iso-nonyl)-cyclohexane-1,2-dicarboxylate (DINCH).

scientific article published on 7 February 2017

Exposure of nursery school children and their parents and teachers to di-n-butylphthalate and butylbenzylphthalate

scientific article

Exposure to phthalates in 5-6 years old primary school starters in Germany--a human biomonitoring study and a cumulative risk assessment

scientific article published on 2 March 2011

Exposure to the plasticizer di(2-ethylhexyl) terephthalate (DEHTP) in Portuguese children - Urinary metabolite levels and estimated daily intakes.

scientific article published on 10 April 2017

Fetal growth and prenatal exposure to bisphenol A: the generation R study

scientific article

First steps toward harmonized human biomonitoring in Europe: demonstration project to perform human biomonitoring on a European scale

scientific article

Fish consumption patterns and hair mercury levels in children and their mothers in 17 EU countries.

scientific article published on 6 February 2015

Framework for the development and application of environmental biological monitoring guidance values

scientific article published on 7 June 2012

Gender differences in cadmium and cotinine levels in prepubertal children.

scientific article published on 18 December 2014

German Environmental Specimen Bank: 24-hour urine samples from 1999 to 2017 reveal rapid increase in exposure to the para-phthalate plasticizer di(2-ethylhexyl) terephthalate (DEHTP)

scientific article published on 03 September 2019

Hair mercury and urinary cadmium levels in Belgian children and their mothers within the framework of the COPHES/DEMOCOPHES projects

scientific article published on 10 December 2013

Hexamoll® DINCH and DPHP metabolites in urine of children and adolescents in Germany. Human biomonitoring results of the German Environmental Survey GerES V, 2014-2017

scientific article published on 01 October 2019

Human Biomonitoring of Glyphosate Exposures: State-of-the-Art and Future Research Challenges

scientific article published on 18 August 2020

Human Metabolism and Urinary Excretion Kinetics of Nonylphenol in Three Volunteers after a Single Oral Dose

scientific article published in 2021

Human biomonitoring of phthalate exposure in Austrian children and adults and cumulative risk assessment

scientific article published on 21 April 2015

Human metabolism and excretion kinetics of aniline after a single oral dose

scientific article published on 2 August 2015

Human metabolism and excretion kinetics of the fragrance lysmeral after a single oral dosage

scientific article

Human metabolism and urinary excretion kinetics of di-n-butyl adipate (DnBA) after oral and dermal administration in three volunteers

scientific article published in 2021

Human metabolism and urinary excretion of seven neonicotinoids and neonicotinoid-like compounds after controlled oral dosages

scientific article published in 2021

Identification of 2,5-dimethyl-4-hydroxy-3[2H]-furanone beta-D-glucuronide as the major metabolite of a strawberry flavour constituent in humans

scientific article published on 01 August 1997

Identifying sources of phthalate exposure with human biomonitoring: results of a 48h fasting study with urine collection and personal activity patterns

scientific article published on 18 January 2013

Impact of different welding techniques on biological effect markers in exhaled breath condensate of 58 mild steel welders.

scientific article

Inter- and intra-individual variation in urinary biomarker concentrations over a 6-day sampling period. Part 1: metals

scientific article published on 13 August 2014

Inter- and intra-individual variation in urinary biomarker concentrations over a 6-day sampling period. Part 2: personal care product ingredients

scientific article published on 20 June 2014

Interlaboratory comparison investigations (ICI) and external quality assurance schemes (EQUAS) for cadmium in urine and blood: Results from the HBM4EU project

scientific article published on 11 March 2021

Internal exposure of nursery-school children and their parents and teachers to di(2-ethylhexyl)phthalate (DEHP).

scientific article published in January 2004

Internal exposure of the general population to DEHP and other phthalates--determination of secondary and primary phthalate monoester metabolites in urine

scientific article (publication date: October 2003)

Internal phthalate exposure over the last two decades--a retrospective human biomonitoring study

scientific article published on 30 March 2007

Interpreting biomarker data from the COPHES/DEMOCOPHES twin projects: Using external exposure data to understand biomarker differences among countries

scientific article

Intrauterine Exposure to Paracetamol and Aniline Impairs Female Reproductive Development by Reducing Follicle Reserves and Fertility

scientific article published on 5 January 2016

Is bisphenol-A exposure during pregnancy associated with blood glucose levels or diagnosis of gestational diabetes? ⬇️

journal article published in 2013

Lessons learnt on recruitment and fieldwork from a pilot European human biomonitoring survey

scientific article published on 31 October 2014

Levels of phthalate metabolites in urine among mother-child-pairs - results from the Duisburg birth cohort study, Germany.

scientific article published on 7 October 2011

Linking a dermal permeation and an inhalation model to a simple pharmacokinetic model to study airborne exposure to di(n-butyl) phthalate.

scientific article

Measurements of dermal uptake of nicotine directly from air and clothing

scientific article

Mercury analysis in hair: Comparability and quality assessment within the transnational COPHES/DEMOCOPHES project

scientific article published on 4 December 2014

Mercury exposure in Ireland: results of the DEMOCOPHES human biomonitoring study

scientific article

Metabolism and elimination of N-ethyl-2-pyrrolidone (NEP) in human males after oral dosage.

scientific article published on 14 November 2013

Metabolism and elimination of methyl, iso- and n-butyl paraben in human urine after single oral dosage

scientific article published on 25 November 2015

Metabolism and urinary excretion kinetics of di(2-ethylhexyl) adipate (DEHA) in four human volunteers after a single oral dose

scientific article published on 06 December 2019

Metabolism and urinary excretion kinetics of di(2-ethylhexyl) terephthalate (DEHTP) in three male volunteers after oral dosage

scientific article published on 26 April 2016

Metabolism of the plasticizer and phthalate substitute diisononyl-cyclohexane-1,2-dicarboxylate (DINCH(®)) in humans after single oral doses

scientific article published on 01 December 2012

Metabolites of n-Butylparaben and iso-Butylparaben Exhibit Estrogenic Properties in MCF-7 and T47D Human Breast Cancer Cell Lines

scientific article published on 01 July 2018

Metabolites of the alkyl pyrrolidone solvents NMP and NEP in 24-h urine samples of the German Environmental Specimen Bank from 1991 to 2014

scientific article published on 22 August 2018

Misuse of blood serum to assess exposure to bisphenol A and phthalates.

scientific article published on January 2013

Mothers and children are related, even in exposure to chemicals present in common consumer products

scientific article published on 21 May 2019

N-Acetyl-4-aminophenol (paracetamol), N-acetyl-2-aminophenol and acetanilide in urine samples from the general population, individuals exposed to aniline and paracetamol users

scientific article published on 6 December 2013

N-acetyl-4-aminophenol (paracetamol) in urine samples of 6-11-year-old Danish school children and their mothers

scientific article published on 24 July 2014

NTP center for the evaluation of risks to human reproduction reports on phthalates: addressing the data gaps

scientific article published on 01 August 2004

New gas chromatographic-mass spectrometric method for the determination of urinary pyrethroid metabolites in environmental medicine

scientific article published in October 2002

New metabolites of di(2-ethylhexyl)phthalate (DEHP) in human urine and serum after single oral doses of deuterium-labelled DEHP.

scientific article published on 8 February 2005

Non-phthalate plasticizers in German daycare centers and human biomonitoring of DINCH metabolites in children attending the centers (LUPE 3).

scientific article

Obesity or diet? Levels and determinants of phthalate body burden - A case study on Portuguese children.

scientific article published on 6 February 2018

Occurrence and daily variation of phthalate metabolites in the urine of an adult population

scientific article published on 19 December 2006

On-line clean-up by multidimensional liquid chromatography-electrospray ionization tandem mass spectrometry for high throughput quantification of primary and secondary phthalate metabolites in human urine

scientific article

Optimal Exposure Biomarkers for Nonpersistent Chemicals in Environmental Epidemiology

scientific article

Oxidatively damaged guanosine in white blood cells and in urine of welders: associations with exposure to welding fumes and body iron stores

scientific article

Parabens in 24 h urine samples of the German Environmental Specimen Bank from 1995 to 2012.

scientific article

Penetration of beta-naphthylamine and o-toluidine through human skin in vitro

scientific article published on 5 April 2006

Phthalate exposure and neurodevelopmental outcomes in early school age children from Poland

scientific article published on 18 October 2019

Phthalate exposure during cold plastisol application--a human biomonitoring study.

scientific article published on 16 June 2011

Phthalate exposure in pregnant women and newborns - the urinary metabolite excretion pattern differs distinctly

scientific article published on 7 March 2013

Phthalate metabolites and bisphenol A in urines from German school-aged children: results of the Duisburg birth cohort and Bochum cohort studies.

scientific article published on 12 June 2014

Phthalate metabolites in urine of children and adolescents in Germany. Human biomonitoring results of the German Environmental Survey GerES V, 2014-2017

scientific article published on 12 February 2020

Pilot study on the naphthalene exposure of German adults and children by means of urinary 1- and 2-naphthol levels

scientific article published in October 2004

Pilot study testing a European human biomonitoring framework for biomarkers of chemical exposure in children and their mothers: experiences in the UK.

scientific article published on 4 June 2015

Policy recommendations and cost implications for a more sustainable framework for European human biomonitoring surveys

scientific article published on 16 December 2014

Population variability of phthalate metabolites and bisphenol A concentrations in spot urine samples versus 24- or 48-h collections

scientific article published on 6 June 2012

Pre-pubertal exposure with phthalates and bisphenol A and pubertal development

scientific article published on 20 November 2017

Prenatal exposure to acetaminophen and children's language development at 30 months

scientific article published on 10 November 2017

Quantification of biomarkers of environmental exposure to di(isononyl)cyclohexane-1,2-dicarboxylate (DINCH) in urine via HPLC-MS/MS

scientific article published on 28 March 2012

Quantification of four major metabolites of embryotoxic N-methyl- and N-ethyl-2-pyrrolidone in human urine by cooled-injection gas chromatography and isotope dilution mass spectrometry

scientific article published on 29 March 2012

Rapid determination of N-acetyl-4-aminophenol (paracetamol) in urine by tandem mass spectrometry coupled with on-line clean-up by two dimensional turbulent flow/reversed phase liquid chromatography

scientific article published on 27 February 2013

Rapid determination of nine parabens and seven other environmental phenols in urine samples of German children and adults

scientific article published on 20 June 2014

Rapid quantification of seven major neonicotinoids and neonicotinoid-like compounds and their key metabolites in human urine

scientific article published in 2023

Refined reference doses and new procedures for phthalate mixture risk assessment focused on male developmental toxicity

scientific article published on 23 December 2019

Reliability of concentrations of organophosphate pesticide metabolites in serial urine specimens from pregnancy in the Generation R Study

scientific article

Reply to: Shukla et al., Commentary on: Prenatal exposure to acetaminophen and children's language development at 30 months

scientific article published on 03 May 2018

Reproducibility of urinary bisphenol A concentrations measured during pregnancy in the Generation R Study

scientific article

Response to "Comment on 'Optimal Exposure Biomarkers for Nonpersistent Chemicals in Environmental Epidemiology'".

scientific article published on April 2016

Role of clothing in both accelerating and impeding dermal absorption of airborne SVOCs.

scientific article published on 10 June 2015

Sensitive and selective quantification of glyphosate and aminomethylphosphonic acid (AMPA) in urine of the general population by gas chromatography-tandem mass spectrometry

scientific article published on 26 August 2020

Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium

scientific article published on 10 July 2019

Smoking and urinary cotinine by socioeconomic status in the Heinz Nixdorf Recall Study

scientific article published on 25 February 2019

Sources of variability in biomarker concentrations

scientific article published on January 2014

The Danish contribution to the European DEMOCOPHES project: A description of cadmium, cotinine and mercury levels in Danish mother-child pairs and the perspectives of supplementary sampling and measurements.

scientific article published on 14 October 2014

The European COPHES/DEMOCOPHES project: towards transnational comparability and reliability of human biomonitoring results

scientific article

The concentration of bisphenol A in urine is affected by specimen collection, a preservative, and handling

scientific article published on 27 July 2013

The contribution of diet to total bisphenol A body burden in humans: results of a 48 hour fasting study

scientific article published on 29 September 2012

The promise of exposure science

scientific article published on 12 January 2011

Time course of phthalate cumulative risks to male developmental health over a 27-year period: Biomonitoring samples of the German Environmental Specimen Bank

scientific article published on 06 February 2020

Time trend of exposure to the phthalate plasticizer substitute DINCH in Germany from 1999 to 2017: Biomonitoring data on young adults from the Environmental Specimen Bank (ESB)

scientific article published on 01 August 2019

Toxicokinetics of N-ethyl-2-pyrrolidone and its metabolites in blood, urine and amniotic fluid of rats after oral administration

scientific article published on 07 February 2019

Transdermal Uptake of Diethyl Phthalate and Di(n-butyl) Phthalate Directly from Air: Experimental Verification

scientific article

Ubiquitous presence of paracetamol in human urine: sources and implications.

scientific article published on 04 March 2014

Unexpected, ubiquitous exposure of pregnant Brazilian women to diisopentyl phthalate, one of the most potent antiandrogenic phthalates

scientific article published on 20 July 2018

Urinary BPA measurements in children and mothers from six European member states: Overall results and determinants of exposure.

scientific article published on 13 October 2014

Urinary Phthalate Concentrations in Mothers and Their Children in Ireland: Results of the DEMOCOPHES Human Biomonitoring Study

scientific article

Urinary di(2-ethylhexyl)phthalate (DEHP)--metabolites and male human markers of reproductive function

scientific article published on 3 September 2009

Urinary levels of eight phthalate metabolites and bisphenol A in mother-child pairs from two Spanish locations

scientific article published on August 2014

Urinary metabolite excretion after oral dosage of bis(2-propylheptyl) phthalate (DPHP) to five male volunteers--characterization of suitable biomarkers for human biomonitoring

scientific article published on 25 June 2014

Urinary metabolites of the UV filter 2-Ethylhexyl salicylate as biomarkers of exposure in humans

scientific article published on 03 April 2019

Urinary metabolites of the UV filter octocrylene in humans as biomarkers of exposure

scientific article published on 09 February 2019

Urinary parabens and triclosan concentrations and associated exposure characteristics in a Korean population-A comparison between night-time and first-morning urine

scientific article published on 19 March 2018

Visible and subclinical skin changes in male and female dispatch department workers of newspaper printing plants

scientific article

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