List of works by Elisa Giannoni

22 : 6n-3 DHA inhibits differentiation of prostate fibroblasts into myofibroblasts and tumorigenesis

scientific article

5-fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like traits

scientific article published on 21 October 2015

A novel redox-based switch: LMW-PTP oxidation enhances Grb2 binding and leads to ERK activation

scientific article published on 28 July 2006

A nucleophilic catalysis step is involved in the hydrolysis of aryl phosphate monoesters by human CT acylphosphatase

scientific article (publication date: 3 January 2003)

Acylphosphatase is a strong apoptosis inducer in HeLa cell line

scientific article published on May 2000

Acylphosphatase possesses nucleoside triphosphatase and nucleoside diphosphatase activities

scientific article published on July 2000

Anchorage-dependent cell growth: tyrosine kinases and phosphatases meet redox regulation

scientific article

Anoikis molecular pathways and its role in cancer progression

scientific article

Anoikis: a necessary death program for anchorage-dependent cells

scientific article published on 25 July 2008

Anoikis: an emerging hallmark in health and diseases

scientific article

Beta-catenin interacts with low-molecular-weight protein tyrosine phosphatase leading to cadherin-mediated cell-cell adhesion increase.

scientific article published on November 2002

Cancer associated fibroblasts exploit reactive oxygen species through a proinflammatory signature leading to epithelial mesenchymal transition and stemness

scientific article published on 28 March 2011

Cancer-associated fibroblasts and M2-polarized macrophages synergize during prostate carcinoma progression

scientific article published on 3 June 2013

Cancer-associated fibroblasts promote prostate cancer malignancy via metabolic rewiring and mitochondrial transfer

scientific article published on 01 April 2019

Carbonic anhydrase IX from cancer-associated fibroblasts drives epithelial-mesenchymal transition in prostate carcinoma cells

scientific article published on 08 May 2013

Chronic resveratrol treatment ameliorates cell adhesion and mitigates the inflammatory phenotype in senescent human fibroblasts

scientific article

Cloning of murine low molecular weight phosphotyrosine protein phosphatase cDNA: identification of a new isoform

scientific journal article

Development of Enzymatic Activity during Protein Folding

scientific article published in Journal of Biological Chemistry

Down-regulation of platelet-derived growth factor receptor signaling during myogenesis.

scientific article published in December 2003

EMT and oxidative stress: a bidirectional interplay affecting tumor malignancy

scientific article

EphA2 induces metastatic growth regulating amoeboid motility and clonogenic potential in prostate carcinoma cells

scientific article published on 4 January 2011

EphA2-mediated mesenchymal-amoeboid transition induced by endothelial progenitor cells enhances metastatic spread due to cancer-associated fibroblasts

scientific article published on 19 August 2012

EphrinA1 activates a Src/focal adhesion kinase-mediated motility response leading to rho-dependent actino/myosin contractility

scientific article published on 22 April 2007

EphrinA1 repulsive response is regulated by an EphA2 tyrosine phosphatase

scientific article

Etoposide-Bevacizumab a new strategy against human melanoma cells expressing stem-like traits

scientific article published on 09 June 2016

Globular adiponectin activates motility and regenerative traits of muscle satellite cells

scientific article (publication date: 2012)

Globular adiponectin as a complete mesoangioblast regulator: role in proliferation, survival, motility, and skeletal muscle differentiation.

scientific article published on 20 January 2010

HIF-1α stabilization by mitochondrial ROS promotes Met-dependent invasive growth and vasculogenic mimicry in melanoma cells

scientific article

Hydrogen peroxide triggers the formation of a disulfide dimer of muscle acylphosphatase and modifies some functional properties of the enzyme

scientific article

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

scientific article (publication date: 4 April 2002)

Insight into the role of low molecular weight phosphotyrosine phosphatase (LMW-PTP) on platelet-derived growth factor receptor (PDGF-r) signaling. LMW-PTP controls PDGF-r kinase activity through TYR-857 dephosphorylation

scientific article published on 30 July 2002

Insulin inhibits platelet-derived growth factor-induced cell proliferation.

scientific article published on 3 November 2004

Integrated gene and miRNA expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation

scientific article published on 8 September 2015

Intracellular reactive oxygen species activate Src tyrosine kinase during cell adhesion and anchorage-dependent cell growth

scientific article

Involvement of the tyrosine phosphorylation on GSH transport in NIH3T3 fibroblasts

scientific article published on March 2003

Kinase-dependent and -independent roles of EphA2 in the regulation of prostate cancer invasion and metastasis

scientific article

LMW-PTP is a positive regulator of tumor onset and growth

scientific article published on May 2004

Lactate Rewires Lipid Metabolism and Sustains a Metabolic-Epigenetic Axis in Prostate Cancer

scientific article published on 01 April 2022

Low molecular weight protein-tyrosine phosphatase is involved in growth inhibition during cell differentiation

scientific article

Lymphocyte function-associated antigen-1-mediated T cell adhesion is impaired by low molecular weight phosphotyrosine phosphatase-dependent inhibition of FAK activity

scientific article

Mesenchymal to amoeboid transition is associated with stem-like features of melanoma cells

scientific article

Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells

scientific article published on 16 August 2016

Metformin is also effective on lactic acidosis-exposed melanoma cells switched to oxidative phosphorylation

scientific article published on 6 June 2016

Microenvironment and tumor cell plasticity: an easy way out.

scientific article published on 31 January 2013

Mitochondrial Oxidative Stress due to Complex I Dysfunction Promotes Fibroblast Activation and Melanoma Cell Invasiveness.

scientific article published on 4 January 2012

New perspectives in PDGF receptor downregulation: the main role of phosphotyrosine phosphatases.

scientific article published on May 2002

Norepinephrine promotes tumor microenvironment reactivity through β3-adrenoreceptors during melanoma progression

scientific article published on March 2015

Nutrient Exploitation within the Tumor-Stroma Metabolic Crosstalk

scientific article published on 6 December 2016

Reactive Oxygen Species in Stem Cells

scientific article published on 29 July 2015

Reactive oxygen species as essential mediators of cell adhesion: the oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion.

scientific article

Reciprocal activation of prostate cancer cells and cancer-associated fibroblasts stimulates epithelial-mesenchymal transition and cancer stemness

scientific article published on 10 August 2010

Reciprocal metabolic reprogramming through lactate shuttle coordinately influences tumor-stroma interplay

scientific article

Redox circuitries driving Src regulation

scientific article published on 20 September 2013

Redox regulation of anoikis resistance of metastatic prostate cancer cells: key role for Src and EGFR-mediated pro-survival signals

scientific article published on 20 April 2009

Redox regulation of anoikis: reactive oxygen species as essential mediators of cell survival.

scientific article published on 8 February 2008

Redox regulation of ephrin/integrin cross-talk.

scientific article published on 29 January 2007

Redox regulation of platelet-derived-growth-factor-receptor: role of NADPH-oxidase and c-Src tyrosine kinase

scientific article

Redox-based escape mechanism from death: the cancer lesson.

scientific article

Role of microenvironment on neuroblastoma SK-N-AS SDHB-silenced cell metabolism and function

scientific article published on 25 March 2015

Senescent stroma promotes prostate cancer progression: the role of miR-210.

scientific article

Short amino acid stretches can mediate amyloid formation in globular proteins: the Src homology 3 (SH3) case

scientific article

Sphingosine 1-phosphate stimulation of NADPH oxidase activity: relationship with platelet-derived growth factor receptor and c-Src kinase

scientific article published on February 2007

Src redox regulation: again in the front line

scientific article published on 29 April 2010

Stromal fibroblasts synergize with hypoxic oxidative stress to enhance melanoma aggressiveness

scientific article

Stromal-induced downregulation of miR-1247 promotes prostate cancer malignancy

Succinate dehydrogenase subunit B mutations modify human neuroblastoma cell metabolism and proliferation

scientific article published on 5 March 2014

Systemic sclerosis endothelial cells recruit and activate dermal fibroblasts by induction of a connective tissue growth factor (CCN2)/transforming growth factor β-dependent mesenchymal-to-mesenchymal transition

scientific article

Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs oxphos and prostate cancer metastatic spread.

scientific article published on 27 June 2015

Targeting the Metabolic Reprogramming That Controls Epithelial-to-Mesenchymal Transition in Aggressive Tumors

scientific article published on 14 March 2017

The low M(r) protein-tyrosine phosphatase is involved in Rho-mediated cytoskeleton rearrangement after integrin and platelet-derived growth factor stimulation.

scientific article published on February 2000

The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style

scientific article published on March 2014

The role of M1 and M2 macrophages in prostate cancer in relation to extracapsular tumor extension and biochemical recurrence after radical prostatectomy

scientific article published on 11 March 2014

The “click-on-tube” approach for the production of efficient drug carriers based on oxidized multi-walled carbon nanotubes

scientific article published on 09 May 2016

Time-dependent stabilization of hypoxia inducible factor-1α by different intracellular sources of reactive oxygen species

scientific article

Two vicinal cysteines confer a peculiar redox regulation to low molecular weight protein tyrosine phosphatase in response to platelet-derived growth factor receptor stimulation

scientific article

Zoledronic Acid Inhibits the RhoA-mediated Amoeboid Motility of Prostate Cancer Cells

scientific article published on 01 January 2019

Zoledronic acid impairs stromal reactivity by inhibiting M2-macrophages polarization and prostate cancer-associated fibroblasts

scientific article published on 20 May 2016

miR-155 Drives Metabolic Reprogramming of ER+ Breast Cancer Cells Following Long-Term Estrogen Deprivation and Predicts Clinical Response to Aromatase Inhibitors

scientific article published on 21 January 2016

miR-205 hinders the malignant interplay between prostate cancer cells and associated fibroblasts

scientific article published on 17 September 2013