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List of works by Hye Seung Lee

A subset of diffuse-type gastric cancer is susceptible to mTOR inhibitors and checkpoint inhibitors

scientific article published on 12 March 2019

Aberrant methylation of the specific CpG island portion regulates cyclooxygenase-2 gene expression in human gastric carcinomas.

scientific article published on October 2003

Adiponectin receptor expression in gastric carcinoma: implications in tumor development and progression

scientific article published on 29 January 2013

Alteration of E-cadherin-mediated adhesion protein is common, but microsatellite instability is uncommon in young age gastric cancers

scientific article published on 01 February 2003

Alteration of O6-methylguanine-DNA methyltransferase in colorectal neoplasms in sporadic and familial adenomatous polyposis patients

scientific article

Analysis of 320 gastroenteropancreatic neuroendocrine tumors identifies TS expression as independent biomarker for survival

scientific article published on 6 January 2014

Annexin A10 expression correlates with serrated pathway features in colorectal carcinoma with microsatellite instability

scientific article published on 7 June 2014

Author Correction: Comparative analysis of HER2 copy number between plasma and tissue samples in gastric cancer using droplet digital PCR

scientific article published on 15 May 2020

BRAF, PIK3CA, and HER2 Oncogenic Alterations According to KRAS Mutation Status in Advanced Colorectal Cancers with Distant Metastasis

scientific article

Bilateral anterior uveitis as an unusual manifestation of Kikuchi-Fujimoto disease

scientific article

Caveolin 1 Expression Correlates with Poor Prognosis and Focal Adhesion Kinase Expression in Gastric Cancer ⬇️

scientific article published on October 3, 2012

Change in the Interstitial Cells of Cajal and nNOS Positive Neuronal Cells with Aging in the Stomach of F344 Rats

scientific article

Changes in aberrant DNA methylation after Helicobacter pylori eradication: a long-term follow-up study

scientific article published on 12 June 2013

Changes in the Clinical and Pathological Characteristics of Gastric Cancer during the Last 16 Years: A Study of a Single Institution in Korea

scientific article published in 2019

Characterisation of PD-L1-positive subsets of microsatellite-unstable colorectal cancers

scientific article published on 12 July 2016

Chemotherapy-associated hepatopathy in korean colorectal cancer liver metastasis patients: oxaliplatin-based chemotherapy and sinusoidal injury.

scientific article

Circulating Methylated Septin 9 Nucleic Acid in the Plasma of Patients with Gastrointestinal Cancer in the Stomach and Colon ⬇️

scientific article published on June 1, 2013

Clinical and prognostic value of MET gene copy number gain and chromosome 7 polysomy in primary colorectal cancer patients

scientific article

Clinical significance of protein expression of cyclooxygenase-2 and somatostatin receptors in gastroenteropancreatic neuroendocrine tumors

scientific article

Clinicopathologic and protein expression differences between cardia carcinoma and noncardia carcinoma of the stomach

scientific article

Clinicopathologic characteristics of Epstein-Barr virus-incorporated gastric cancers in Korea

scientific article published in January 2001

Clinicopathologic features of gastric cancer with synchronous and metachronous colorectal cancer in Korea: are microsatellite instability and p53 overexpression useful markers for predicting colorectal cancer in gastric cancer patients?

scientific article published on 7 October 2015

Clinicopathologic implication of meticulous pathologic examination of regional lymph nodes in gastric cancer patients

scientific article

Clinicopathologic implications of immune classification by PD-L1 expression and CD8-positive tumor-infiltrating lymphocytes in stage II and III gastric cancer patients

scientific article

Clinicopathologic significance of human leukocyte antigen class I expression in patients with stage II and III gastric cancer

scientific article published on 16 October 2019

Clinicopathologic, molecular, and prognostic implications of the loss of EPCAM expression in colorectal carcinoma.

scientific article published on 30 October 2015

Clinicopathological characteristics, microsatellite instability, and expression of mucin core proteins and p53 in colorectal mucinous adenocarcinomas in relation to location

scientific article

Combination of epithelial-mesenchymal transition and cancer stem cell-like phenotypes has independent prognostic value in gastric cancer

scientific article published on 21 October 2011

Comparative analysis of DNA methylation between primary and metastatic gastric carcinoma

scientific article

Comparative analysis of HER2 copy number between plasma and tissue samples in gastric cancer using droplet digital PCR

scientific article published on 06 March 2020

Comparative analysis of protein expressions in primary and metastatic gastric carcinomas

scientific article published on 5 October 2008

Comparative validation of assessment criteria for Crohn-like lymphoid reaction in colorectal carcinoma

scientific article published on 16 October 2014

Comprehensive genetic features of gastric mixed adenoneuroendocrine carcinomas and pure neuroendocrine carcinomas

scientific article published on 28 September 2020

Conversion Surgery in Metastatic Gastric Cancer and Cancer Dormancy as a Prognostic Biomarker

scientific article published on 30 December 2019

Copy number aberrations of genes regulating normal thymus development in thymic epithelial tumors.

scientific article published on 26 February 2013

Correlation between microsatellite instability-high phenotype and occult lymph node metastasis in gastric carcinoma

scientific article published on 31 December 2014

Curative Resection for Metachronous Pulmonary Metastases from Colorectal Cancer: Analysis of Survival Rates and Prognostic Factors

scientific article published on 09 May 2016

Cytokeratin expression profile in gastric carcinomas

scientific article

Deregulation of the cell polarity protein Lethal giant larvae 2 (Lgl2) correlates with gastric cancer progression

scientific article published on 13 December 2013

Development and Validation of an Easy-to-Implement, Practical Algorithm for the Identification of Molecular Subtypes of Gastric Cancer: Prognostic and Therapeutic Implications

scientific article published on 01 August 2019

Differential Features of Microsatellite-Unstable Colorectal Carcinomas Depending on EPCAM Expression Status.

scientific article

Differential protein expression between esophageal squamous cell carcinoma and dysplasia, and prognostic significance of protein markers

scientific article published in January 2005

Differential protein immunoexpression profiles in appendiceal mucinous neoplasms: a special reference to classification and predictive factors

scientific article published on 15 May 2009

Digital polymerase chain reaction for detecting c-MYC copy number gain in tissue and cell-free plasma samples of colorectal cancer patients

scientific article published in Scientific Reports

Distinct clinical outcomes of two CIMP-positive colorectal cancer subtypes based on a revised CIMP classification system

scientific article

EGFR or HER2 inhibition modulates the tumor microenvironment by suppression of PD-L1 and cytokines release

scientific article published on 12 July 2017

Early colorectal epithelial neoplasm in Korea: a multicenter survey of pathologic diagnosis

scientific article published on 25 June 2013

Effects of fixation and storage of human tissue samples on nucleic Acid preservation

scientific article published on 25 February 2014

Endoscopic and histologic analysis of gastric mucosa-associated lymphoid tissue in children with Helicobacter pylori infection

scientific article published in September 2013

Epstein-barr virus-positive gastric carcinoma has a distinct protein expression profile in comparison with epstein-barr virus-negative carcinoma

scientific article published in March 2004

Evaluation of Fibroblast Growth Factor Receptor 2 Expression, Heterogeneity and Clinical Significance in Gastric Cancer

scientific article published on 31 October 2015

Evaluation of HER-2 gene status in gastric carcinoma using immunohistochemistry, fluorescence in situ hybridization, and real-time quantitative polymerase chain reaction

scientific article published on 6 June 2007

Expression and mutational status of c-kit in thymic epithelial tumors

scientific article published on September 2010

Expression of DNA Damage Response Markers in Early-Onset or Familial Gastric Cancers

scientific article published on 25 May 2019

Expression of Lewis antigens and their precursors in gastric mucosa: relationship with Helicobacter pylori infection and gastric carcinogenesis

scientific article published in May 2006

Expression of human leukocyte antigen class I and β2-microglobulin in colorectal cancer and its prognostic impact

scientific article published on 06 November 2020

Expression of the immune checkpoint receptors PD-1, LAG3, and TIM3 in the immune context of stage II and III gastric cancer by using single and chromogenic multiplex immunohistochemistry

scientific article published on 25 July 2021

Expression status of wild-type HSP110 correlates with HSP110 T17 deletion size and patient prognosis in microsatellite-unstable colorectal cancer

scientific article published on 13 September 2013

Favorable prognosis in colorectal cancer patients with co-expression of c-MYC and ß-catenin

scientific article

Fibroblast Growth Factor Receptor 1 (FGFR1) Amplification Detected by Droplet Digital Polymerase Chain Reaction (ddPCR) Is a Prognostic Factor in Colorectal Cancers

scientific article published on 08 May 2019

Fibroblast Growth Factor Receptor 1 Gene Copy Number and mRNA Expression in Primary Colorectal Cancer and Its Clinicopathologic Correlation

scientific article

Gastric-type expression signature in serrated pathway–associated colorectal tumors

scientific article published in May 2015

HER2 status in colorectal cancer: its clinical significance and the relationship between HER2 gene amplification and expression

scientific article

HER3 protein expression in relation to HER2 positivity in patients with primary colorectal cancer: clinical relevance and prognostic value

scientific article

Helicobacter pylori-infection-associated CpG island hypermethylation in the stomach and its possible association with polycomb repressive marks

scientific article published in May 2008

Immunohistochemical analysis of cell cycle-related molecules in gastric carcinoma: prognostic significance, correlation with clinicopathological parameters, proliferation and apoptosis

scientific article published on 15 December 2008

Immunoscore encompassing CD3+ and CD8+ T cell densities in distant metastasis is a robust prognostic marker for advanced colorectal cancer.

scientific article

Immunoscore is a strong predictor of survival in the prognosis of stage II/III gastric cancer patients following 5-FU-based adjuvant chemotherapy

scientific article published on 12 August 2020

Impact of intratumoral expression levels of fluoropyrimidine-metabolizing enzymes on treatment outcomes of adjuvant S-1 therapy in gastric cancer

scientific article

Influence of IL1B polymorphism on CpG island hypermethylation in Helicobacter pylori-infected gastric cancer

scientific article published on 20 April 2010

Insulin-like growth factor-1 receptor and phosphorylated AKT-serine 473 expression in 132 resected thymomas and thymic carcinomas

scientific article

Intestinal adenocarcinoma arising in a mature cystic teratoma of the ovary: a case report

scientific article published on 19 May 2006

Intratumoral Fusobacterium nucleatum abundance correlates with macrophage infiltration and CDKN2A methylation in microsatellite-unstable colorectal carcinoma

scientific article published on 8 June 2017

Leptin, MUC2 and mTOR in Appendiceal Mucinous Neoplasms

scientific article published in 2012

Ligand-Independent Epidermal Growth Factor Receptor Overexpression Correlates with Poor Prognosis in Colorectal Cancer

scientific article published on 17 January 2018

Liquid-based cytology of villoglandular adenocarcinoma of the cervix: a report of 3 cases.

scientific article

Loss of ARID1A Expression is Related to Gastric Cancer Progression, Epstein-Barr Virus Infection, and Mismatch Repair Deficiency

scientific article

Molecular Testing for Gastrointestinal Cancer.

scientific article published on 19 February 2017

Nuclear factor-kappaB activation correlates with better prognosis and Akt activation in human gastric cancer

scientific article

Oligonol inhibits dextran sulfate sodium-induced colitis and colonic adenoma formation in mice

scientific article published on 15 May 2013

Open versus laparoscopic surgery for mid-rectal or low-rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): survival outcomes of an open-label, non-inferiority, randomised controlled trial

scientific article published on 15 May 2014

PIK3CA mutations are associated with increased tumor aggressiveness and Akt activation in gastric cancer

scientific article published on 28 June 2017

Pathologic Factors Associated with Prognosis after Adjuvant Chemotherapy in Stage II/III Microsatellite-Unstable Colorectal Cancers

scientific article

Performance characteristics of nested polymerase chain reaction vs real-time polymerase chain reaction methods for detecting Mycobacterium tuberculosis complex in paraffin-embedded human tissues

scientific article published in September 2014

Precise pathologic examination decreases the false-negative rate of sentinel lymph node biopsy in gastric cancer

scientific article published on 7 October 2011

Predictive factors for improvement of atrophic gastritis and intestinal metaplasia after Helicobacter pylori eradication: a three-year follow-up study in Korea

scientific article

Predictive power of serum pepsinogen tests for the development of gastric cancer in comparison to the histologic risk index

scientific article published on 20 March 2010

Preoperative staging of gastric cancer by endoscopic ultrasonography and multidetector-row computed tomography

scientific article published in March 2010

Prevalence and risk factors of atrophic gastritis and intestinal metaplasia in a Korean population without significant gastroduodenal disease

scientific article published in August 2008

Prognostic relevance of programmed cell death ligand 1 expression in glioblastoma

scientific article published on 16 November 2017

Prognostic significance of natural killer cell-associated markers in gastric cancer: quantitative analysis using multiplex immunohistochemistry

scientific article published on 24 December 2021

Promoter methylation and silencing of PTEN in gastric carcinoma

scientific article published in March 2002

Rapid, sensitive, and specific detection of Mycobacterium tuberculosis complex by real-time PCR on paraffin-embedded human tissues

scientific article

Repeated Water Avoidance Stress Alters Mucosal Mast Cell Counts, Interleukin-1β Levels with Sex Differences in the Distal Colon of Wistar Rats

scientific article published on 28 July 2016

Reproducibility of the WHO classification of thymomas: practical implications

scientific article published on 29 December 2012

Risk Factors for Metachronous Gastric Neoplasms in Patients Who Underwent Endoscopic Resection of a Gastric Neoplasm

scientific article published on 19 June 2015

Role of Serum Pepsinogen II and Helicobacter pylori Status in the Detection of Diffuse-Type Early Gastric Cancer in Young Individuals in South Korea

scientific article published on 20 September 2019

Role of intestinal metaplasia subtyping in the risk of gastric cancer in Korea

scientific article published on 17 August 2008

Serum VEGF-A and Tumor Vessel VEGFR-2 Levels Predict Survival in Caucasian but Not Asian Patients Undergoing Resection for Gastric Adenocarcinoma

scientific article published on 11 August 2015

Small heterodimer partner (SHP) deficiency protects myocardia from lipid accumulation in high fat diet-fed mice

scientific article published on 10 October 2017

Somatic mutational profiles of stage II and III gastric cancer according to tumor microenvironment immune type

scientific article published on 16 October 2018

Strong cytoplasmic expression of COX2 at the invasive fronts of gallbladder cancer is associated with a poor prognosis.

scientific article published on 5 October 2010

Telomere length, TERT and shelterin complex proteins in hepatocellular carcinomas expressing “stemness”-related markers ⬇️

scientific article published on May 14, 2013

The clinical meaning of the "indefinite for atrophy" lesions within gastric mucosa biopsy specimens in a region with a high prevalence of gastric cancer

scientific article published on 14 July 2019

The discrepancy between genetic polymorphism of p53 codon 72 and the expression of p53 protein in Helicobacter pylori-associated gastric cancer in Korea

scientific article published on 29 January 2009

The prognostic implications of primary tumor location on recurrence in early-stage colorectal cancer with no associated risk factors

scientific article published on 28 March 2018

Thymidylate synthase accelerates Men1-mediated pancreatic tumor progression and reduces survival

scientific article published in 2022

Trastuzumab Specific Epitope Evaluation as a Predictive and Prognostic Biomarker in Gastric Cancer Patients

scientific article published on 26 November 2019

Tumor budding as an indicator of isolated tumor cells in lymph nodes from patients with node-negative colorectal cancer

scientific article

Tumor-Associated Protein Profiles in Kaposi Sarcoma and Mimicking Vascular Tumors, and Their Pathological Implications

scientific article published on 27 June 2019

Whole-Slide Image Analysis Reveals Quantitative Landscape of Tumor-Immune Microenvironment in Colorectal Cancers

scientific article published on 22 November 2019

p27 Loss Is Associated with Poor Prognosis in Gastroenteropancreatic Neuroendocrine Tumors

scientific article

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