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List of works by Massimo Donadelli

A comparison study on RNase A oligomerization induced by cisplatin, carboplatin and oxaliplatin

scientific article published on 9 May 2017

ABCA1/ABCB1 Ratio Determines Chemo- and Immune-Sensitivity in Human Osteosarcoma

scientific article published on 06 March 2020

Activation of the Interleukin-6 promoter by a dominant negative mutant of c-Jun

scientific article published in May 2004

Antioxidant Mechanisms and ROS-Related MicroRNAs in Cancer Stem Cells

scientific article

Autocrine mechanisms of cancer chemoresistance.

scientific article

Autophagy induced by p53-reactivating molecules protects pancreatic cancer cells from apoptosis.

scientific article published on March 2013

Bone marrow stromal cells and the upregulation of interleukin-8 production in human T-cell acute lymphoblastic leukemia through the CXCL12/CXCR4 axis and the NF- B and JNK/AP-1 pathways

article

Bovine seminal ribonuclease triggers Beclin1-mediated autophagic cell death in pancreatic cancer cells.

scientific article published on 31 January 2014

Cannabinoids inhibit energetic metabolism and induce AMPK-dependent autophagy in pancreatic cancer cells.

scientific article published on 13 June 2013

Cytotoxicity of polyspermine-ribonuclease A and polyspermine-dimeric ribonuclease A.

scientific article

Double domain swapping in bovine seminal RNase: formation of distinct N- and C-swapped tetramers and multimers with increasing biological activities

scientific article

Expression of the antiapoptotic protein BAG3 is a feature of pancreatic adenocarcinoma and its overexpression is associated with poorer survival.

scientific article published on 31 August 2012

Extracellular Matrix Composition Modulates the Responsiveness of Differentiated and Stem Pancreatic Cancer Cells to Lipophilic Derivate of Gemcitabine

scientific article published on 22 December 2020

Gemcitabine response in pancreatic adenocarcinoma cells is synergistically enhanced by dithiocarbamate derivatives.

scientific article published on 12 January 2011

Gene expression profiling after treatment with the histone deacetylase inhibitor trichostatin A reveals altered expression of both pro- and anti-apoptotic genes in pancreatic adenocarcinoma cells.

scientific article published in September 2004

Growth delay of human pancreatic cancer cells by methylase inhibitor 5-aza-2'-deoxycytidine treatment is associated with activation of the interferon signalling pathway

scientific article published in January 2005

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Hyaluronic acid-coated liposomes for active targeting of gemcitabine.

scientific article published on 18 June 2013

Hypoxia Dictates Metabolic Rewiring of Tumors: Implications for Chemoresistance

scientific article published on 04 December 2020

Identification of a candidate alternative promoter region of the human Bcl2L11 (Bim) gene

scientific article

Increase of RNase AN-terminus Polarity orC-terminus Apolarity Changes the Two Domains' Propensity To Swap and Form the Two Dimeric Conformers of the Protein†

scientific article published on 01 September 2006

Interplay between ROS and Autophagy in Cancer and Aging: From Molecular Mechanisms to Novel Therapeutic Approaches

scientific article published on 04 August 2019

Low catalase expression confers redox hypersensitivity and identifies an indolent clinical behavior in CLL

scientific article published on 21 February 2018

Mitochondrial uncoupling protein 2 and pancreatic cancer: a new potential target therapy

scientific article

Molecular interplay between mutant p53 proteins and autophagy in cancer cells.

scientific article published on 18 November 2016

Mutant p53 and mTOR/PKM2 regulation in cancer cells.

scientific article published on 7 July 2016

Mutant p53 blocks SESN1/AMPK/PGC-1α/UCP2 axis increasing mitochondrial O· production in cancer cells

article

Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity

article

Mutant p53 proteins alter cancer cell secretome and tumour microenvironment: Involvement in cancer invasion and metastasis

scientific article published on April 2016

Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition.

scientific article published on 12 April 2016

Mutant p53 stimulates chemoresistance of pancreatic adenocarcinoma cells to gemcitabine

scientific article published on 13 October 2014

Mutant p53-Associated Molecular Mechanisms of ROS Regulation in Cancer Cells

scientific article published on 26 February 2020

Onconase dimerization through 3D domain swapping: structural investigations and increase in the apoptotic effect in cancer cells

scientific article published on 28 September 2017

Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner.

scientific article published on 20 December 2014

Proteomic analysis of pancreatic ductal carcinoma cells after combined treatment with gemcitabine and trichostatin A.

scientific article published in November 2005

Proteomic profiling of pancreatic ductal carcinoma cell lines treated with trichostatin-A.

scientific article published in June 2003

Regulation of miR-23b expression and its dual role on ROS production and tumour development.

scientific article published on 19 April 2014

Reprogramming Tumor-Immune Cell Interface in Solid and Hematological Malignancies to Enhance Response to Therapy.

scientific article published on 5 March 2018

Role of mitochondrial uncoupling protein 2 in cancer cell resistance to gemcitabine ⬇️

scientific article published on June 15, 2012

Roles for microRNA 23b in regulating autophagy and development of pancreatic adenocarcinoma

scientific article

Sestrins at the Interface of ROS Control and Autophagy Regulation in Health and Disease.

scientific article

Synergistic effect of trichostatin A and 5-aza-2'-deoxycytidine on growth inhibition of pancreatic endocrine tumour cell lines: a proteomic study.

scientific article published on April 2009

Synergistic inhibition of pancreatic adenocarcinoma cell growth by trichostatin A and gemcitabine.

scientific article published on 22 May 2007

Targeting gemcitabine containing liposomes to CD44 expressing pancreatic adenocarcinoma cells causes an increase in the antitumoral activity.

scientific article published on 4 February 2013

The Mutant p53-Driven Secretome Has Oncogenic Functions in Pancreatic Ductal Adenocarcinoma Cells

scientific article published on 09 June 2020

The antioxidant uncoupling protein 2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreas cancer cells to glycolysis inhibition

scientific article

The cancer secretome and secreted biomarkers.

scientific article published on 6 September 2017

The metabolic landscape of cancer stem cells

scientific article published on 04 September 2015

Trichostatin A alters cytoskeleton and energy metabolism of pancreatic adenocarcinoma cells: An in depth proteomic study.

scientific article published on 2 November 2017

Trichostatin A enhances the response of chemotherapeutic agents in inhibiting pancreatic cancer cell proliferation.

scientific article published on 28 March 2006

Trichostatin A, an inhibitor of histone deacetylases, strongly suppresses growth of pancreatic adenocarcinoma cells.

scientific article published in October 2003

UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism

scientific article

UCP2 inhibition triggers ROS-dependent nuclear translocation of GAPDH and autophagic cell death in pancreatic adenocarcinoma cells.

scientific article

UCP2, a mitochondrial protein regulated at multiple levels.

scientific article published on 27 June 2013

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