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List of works by Martin D Bootman

2-Aminoethoxydiphenyl borate (2-APB) antagonises inositol 1,4,5-trisphosphate-induced calcium release, inhibits calcium pumps and has a use-dependent and slowly reversible action on store-operated calcium entry channels

scientific article published in July 2003

2-aminoethoxydiphenyl borate (2-APB) is a reliable blocker of store-operated Ca2+ entry but an inconsistent inhibitor of InsP3-induced Ca2+ release.

scientific article

A comparison of fluorescent Ca2+ indicator properties and their use in measuring elementary and global Ca2+ signals

scientific article published on 01 October 2000

Activating calcium release through inositol 1,4,5-trisphosphate receptors without inositol 1,4,5-trisphosphate.

scientific article

Alzheimer's disease-associated peptide Aβ42 mobilizes ER Ca(2+) via InsP3R-dependent and -independent mechanisms.

scientific article

Atrial cardiomyocyte calcium signalling.

scientific article published on 03 February 2011

Atrial myocytes demonstrate the diversity of cardiac calcium signalling

scientific article

Basal ryanodine receptor activity suppresses autophagic flux

scientific article

Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate.

scientific article

Bcl-2 interaction with the inositol 1,4,5-trisphosphate receptor: Role in Ca2+ signaling and disease ⬇️

scientific article published on May 31, 2011

Bcl-2 suppresses Ca2+ release through inositol 1,4,5-trisphosphate receptors and inhibits Ca2+ uptake by mitochondria without affecting ER calcium store content

scientific article published on 14 April 2008

Ca2+ entry into PC12 cells initiated by ryanodine receptors or inositol 1,4,5-trisphosphate receptors

scientific article published on January 1998

Ca2+-sensitive fluorescent dyes and intracellular Ca2+ imaging

scientific article published on 01 February 2013

Calcium - a life and death signal

scientific article published in Nature

Calcium Signaling ⬇️

scientific article published on July 1, 2012

Calcium in the heart: when it's good, it's very very good, but when it's bad, it's horrid.

scientific article published on November 2007

Calcium influx: is Homer the missing link?

scientific article published on December 2003

Calcium phosphate crystals induce cell death in human vascular smooth muscle cells: a potential mechanism in atherosclerotic plaque destabilization

scientific article published on 31 July 2008

Calcium phosphate particles stimulate interleukin-1β release from human vascular smooth muscle cells: A role for spleen tyrosine kinase and exosome release.

scientific article published on 20 December 2017

Calcium signaling in cardiac myocytes.

scientific article

Calcium signalling.

scientific article

Calcium signalling: dynamics, homeostasis and remodelling

scientific article (publication date: July 2003)

Calcium signalling: more messengers, more channels, more complexity

scientific article published in August 2002

Calcium-induced calcium release

scientific article published on 01 May 2003

Calcium-modulating cyclophilin ligand desensitizes hormone-evoked calcium release.

scientific article

Cardiac pathology in neuronal ceroid lipofuscinoses (NCL): More than a mere co-morbidity

scientific article published on 19 December 2019

Cell signalling: IP3 receptors channel calcium into cell death.

scientific article

Characterization of elementary Ca2+ release signals in NGF-differentiated PC12 cells and hippocampal neurons

scientific article published in January 1999

Co-incident signalling between mu-opioid and M3 muscarinic receptors at the level of Ca2+ release from intracellular stores: lack of evidence for Ins(1,4,5)P3 receptor sensitization

scientific article published on November 2003

Comparison of the T-tubule system in adult rat ventricular and atrial myocytes, and its role in excitation–contraction coupling and inotropic stimulation

scientific article published on 27 January 2010

Constitutive IP signaling underlies the sensitivity of B-cell cancers to the Bcl-2/IP receptor disruptor BIRD-2

scientific article published on 13 June 2018

Contractile responses to endothelin-1 are regulated by PKC phosphorylation of cardiac myosin binding protein-C in rat ventricular myocytes.

scientific article

Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+.

scientific article published on March 1995

Converting fluorescence data into Ca2+ concentration.

scientific article

Cooking with calcium: the recipes for composing global signals from elementary events.

scientific article

Creating a New Cancer Therapeutic Agent by Targeting the Interaction between Bcl-2 and IP3 Receptors

scientific article published on 03 September 2019

Defective chemoattractant-induced calcium signalling in S100A9 null neutrophils

scientific article published on 30 June 2006

Deleterious effects of calcium indicators within cells; an inconvenient truth

scientific article published on 15 April 2018

Elevated InsP3R expression underlies enhanced calcium fluxes and spontaneous extra-systolic calcium release events in hypertrophic cardiac myocytes.

scientific article published on 17 January 2010

Emerging roles of inositol 1,4,5-trisphosphate signaling in cardiac myocytes

scientific article published on 15 June 2008

Endothelin-1-stimulated InsP3-induced Ca2+ release is a nexus for hypertrophic signaling in cardiac myocytes.

scientific article

Examining Cardiomyocyte Dysfunction Using Acute Chemical Induction of an Ageing Phenotype

scientific article published on 27 December 2019

Exosomes bind to autotaxin and act as a physiological delivery mechanism to stimulate LPA receptor signalling in cells

scientific article published on 24 August 2016

Exposure to GSM RF fields does not affect calcium homeostasis in human endothelial cells, rat pheocromocytoma cells or rat hippocampal neurons

scientific article

Extracellular calcium concentration controls the frequency of intracellular calcium spiking independently of inositol 1,4,5-trisphosphate production in HeLa cells

scientific article published on February 1996

Fetuin-A and albumin alter cytotoxic effects of calcium phosphate nanoparticles on human vascular smooth muscle cells

scientific article

Fluorescence microscopy

scientific article published on 01 October 2014

Functional InsP3 receptors that may modulate excitation-contraction coupling in the heart

scientific article published on 01 July 2000

Fundamentals of Cellular Calcium Signaling: A Primer

scientific article published on 02 January 2020

Glucocorticoid-mediated inhibition of Lck modulates the pattern of T cell receptor-induced calcium signals by down-regulating inositol 1,4,5-trisphosphate receptors

scientific article published on 23 September 2009

Hormone-evoked elementary Ca2+ signals are not stereotypic, but reflect activation of different size channel clusters and variable recruitment of channels within a cluster

scientific article published in October 1998

Hormone-evoked subcellular Ca2+ signals in HeLa cells

scientific article published on August 1996

Inositol 1,4,5-trisphosphate supports the arrhythmogenic action of endothelin-1 on ventricular cardiac myocytes

scientific article published on 01 August 2006

Interaction between store-operated and arachidonate-activated calcium entry

scientific article published on 12 June 2006

Intra-axonal calcium changes after axotomy in wild-type and slow Wallerian degeneration axons

scientific article published on 7 September 2012

Intracellular calcium. Questions about quantal Ca2+ release

scientific article published on 01 February 1994

Loading fluorescent Ca2+ indicators into living cells

scientific article published in February 2013

Mechanisms underlying the neuronal calcium sensor-1-evoked enhancement of exocytosis in PC12 cells

scientific journal article

Melatonin triggers PKA activation in the rodent malaria parasite Plasmodium chabaudi

scientific article published on 22 October 2010

Methacholine and PDGF activate store-operated calcium entry in neuronal precursor cells via distinct calcium entry channels

scientific article

Mitochondria are morphologically and functionally heterogeneous within cells.

scientific article published on April 2002

Mitochondrial Ca(2+) uptake depends on the spatial and temporal profile of cytosolic Ca(2+) signals

scientific article

Molecular cloning and immunolocalization of a novel vertebrate trp homologue from Xenopus

scientific article published in June 1999

New Ca2+ indicator has freedom to express

scientific article published in May 2006

Non-immortalized human neural stem (NS) cells as a scalable platform for cellular assays

scientific article published on 14 July 2011

Normal Ca2+ signalling in glutathione-depleted and dithiothreitol-treated HeLa cells

scientific article published on 01 June 1993

Nuclear calcium signalling by individual cytoplasmic calcium puffs

scientific article published on December 1997

Oncogenic K-Ras suppresses IP₃-dependent Ca²⁺ release through remodelling of the isoform composition of IP₃Rs and ER luminal Ca²⁺ levels in colorectal cancer cell lines.

scientific article published on 12 February 2014

Oncogenic KRAS suppresses store-operated Ca 2+ entry and I CRAC through ERK pathway-dependent remodelling of STIM expression in colorectal cancer cell lines

scientific article published on 14 March 2018

Pacemaking, arrhythmias, inotropy and hypertrophy: the many possible facets of IP3 signalling in cardiac myocytes

scientific article published on 19 April 2007

Persistence of pro-arrhythmic spatio-temporal calcium patterns in atrial myocytes: a computational study of ping waves

scientific article published on 20 July 2012

Prognostic relevance of a T-type calcium channels gene signature in solid tumours: A correlation ready for clinical validation

scientific article published on 28 August 2017

Pulmonary vein sleeve cell excitation-contraction-coupling becomes dysynchronized by spontaneous calcium transients.

scientific article published on June 2015

Quantal Ca2+ release from InsP3-sensitive intracellular Ca2+ stores

scientific article

Redoxing calcium from the ER.

scientific article

Regulation of InsP3 receptor activity by neuronal Ca2+-binding proteins

scientific article

Regulation of ryanodine receptor opening by lumenal Ca(2+) underlies quantal Ca(2+) release in PC12 cells.

scientific article

Ringing changes to the 'bell-shaped curve'

scientific article published on 01 December 1999

Second Messengers

scientific article published in August 2016

Signal transduction. The calcium entry pas de deux

scientific article

Spontaneous, pro-arrhythmic calcium signals disrupt electrical pacing in mouse pulmonary vein sleeve cells

scientific article

Subcellular Ca2+ signals underlying waves and graded responses in HeLa cells

scientific article published in July 1996

Subcellular calcium dynamics in a whole-cell model of an atrial myocyte

scientific article

Synthesis and biological action of novel 4-position-modified derivatives of D-myo-inositol 1,4,5-trisphosphate.

scientific article

T-type calcium channels drive the proliferation of androgen-receptor negative prostate cancer cells

scientific article published on 23 July 2019

Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals

scientific article

Temporal changes in atrial EC-coupling during prolonged stimulation with endothelin-1

scientific article published on 14 June 2007

The JAK3 inhibitor WHI-P154 prevents PDGF-evoked process outgrowth in human neural precursor cells

scientific article

The cellular concentration of Bcl-2 determines its pro- or anti-apoptotic effect

scientific article published on 22 January 2008

The effect of heparin on the inositol 1,4,5-trisphosphate receptor in rat liver microsomes. Dependence on sulphate content and chain length

scientific article published on 01 July 1989

The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis

scientific article published on 09 August 2007

The regulation of autophagy by calcium signals: Do we have a consensus?

scientific article published on 19 August 2017

The role of inositol 1,4,5-trisphosphate receptors in Ca(2+) signalling and the generation of arrhythmias in rat atrial myocytes

scientific article published in June 2002

The spatial pattern of atrial cardiomyocyte calcium signalling modulates contraction

scientific article published on 23 November 2004

The versatility and universality of calcium signalling

scientific article (publication date: October 2000)

Tissue Specificity: Store-Operated Ca2+ Entry in Cardiac Myocytes.

scientific article published in January 2017

To quark or to spark, that is the question ⬇️

scientific article published on July 1, 1997

Two sulphonated dye compounds which compete for inositol 1,4, 5-trisphosphate binding to rat liver microsomes: effects on 5'-phosphatase activity

scientific article published in February 1990

Unifying principles of calcium wave propagation - Insights from a three-dimensional model for atrial myocytes

scientific article published on 4 March 2015

Using Calcium Imaging as a Readout of GPCR Activation

scientific article published on 01 January 2011

Which Ca2+ channels control cardiac E-C coupling?

scientific article published in April 1998

XTRPC1-dependent chemotropic guidance of neuronal growth cones

scientific article published on 08 May 2005

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