Search filters

List of works by Kutty Selva Nandakumar

A Restricted Role for FcγR in the Regulation of Adaptive Immunity.

scientific article published on 9 March 2018

A Shared Epitope of Collagen Type XI and Type II Is Recognized by Pathogenic Antibodies in Mice and Humans with Arthritis.

scientific article

A dominant suppressive MHC class II haplotype interacting with autosomal genes controls autoantibody production and chronicity of arthritis

article

A genetic contamination in MHC-congenic mouse strains reveals a locus on chromosome 10 that determines autoimmunity and arthritis susceptibility

scientific article published on 01 April 2005

A recombinant vaccine effectively induces c5a-specific neutralizing antibodies and prevents arthritis

scientific article (publication date: 20 October 2010)

A single functional group substitution in c5a breaks B cell and T cell tolerance and protects against experimental arthritis

scientific article

Adjuvant properties of a biocompatible thermo-responsive polymer of N-isopropylacrylamide in autoimmunity and arthritis

scientific article

Affinity binding of cells to cryogel adsorbents with immobilized specific ligands: effect of ligand coupling and matrix architecture.

scientific article published in January 2005

Affinity purified anti-citrullinated protein/peptide antibodies target antigens expressed in the rheumatoid joint

scientific article published on 12 August 2014

An encephalomyelitis-specific locus on chromosome 16 in mouse controls disease development and expression of immune-regulatory genes

scientific article

An update on smart biocatalysts for industrial and biomedical applications

scientific article published in February 2018

Analysis of data from breast diseases treated with 5-alpha reductase inhibitors for benign prostatic hyperplasia

scientific article published on 18 April 2019

Animal Models of Rheumatoid Arthritis (I): Pristane-Induced Arthritis in the Rat.

scientific article

Antibodies to citrullinated proteins: molecular interactions and arthritogenicity

scientific article published on January 2010

Antibody-Mediated Arthritis and New Therapeutic Avenues

Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis

scientific article published on January 2006

Antigen-Specific Tolerization and Targeted Delivery as Therapeutic Strategies for Autoimmune Diseases

scientific article published on 24 March 2018

Antileukoproteinase: modulation of neutrophil function and therapeutic effects on anti-type II collagen antibody-induced arthritis

scientific article published in July 2004

Applications of Nanomaterials for Activation and Suppression of Immune Responses

Applications of Nanomaterials for Activation and Suppression of Immune Responses

Applications of polymeric adjuvants in studying autoimmune responses and vaccination against infectious diseases

scientific article published on February 2013

Arthritis induced with cartilage-specific antibodiesis IL-4-dependent

scientific article

Arthritogenic anti-type II collagen antibodies are pathogenic for cartilage-derived chondrocytes independent of inflammatory cells

scientific article published on 01 June 2005

Arthritogenic antibodies specific for a major type II collagen triple-helical epitope bind and destabilize cartilage independent of inflammation

scientific article published on January 2008

Asperosaponin VI protects against bone destructions in collagen induced arthritis by inhibiting osteoclastogenesis

scientific article published on 02 July 2019

Autoantibodies as Diagnostic Markers and Mediator of Joint Inflammation in Arthritis

scientific article published on 27 October 2019

Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism

scientific article published on 27 November 2015

Autophagy induced by STING, an unnoticed and primordial function of cGAS

scientific article published on 29 May 2019

B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production

scientific article

Backcross and partial advanced intercross analysis of nonobese diabetic gene-mediated effects on collagen-induced arthritis reveals an interactive effect by two major loci

article

Biomaterials for Induction and Treatment of Autoimmunity

Blocking of experimental arthritis by cleavage of IgG antibodies in vivo

scientific article published in October 2007

C4b-binding protein (C4BP) inhibits development of experimental arthritis in mice

scientific article published on 14 February 2008

C57BL/6 mice need MHC class II Aq to develop collagen-induced arthritis dependent on autoreactive T cells

scientific article published on 05 October 2012

Cartilage oligomeric matrix protein deficiency promotes early onset and the chronic development of collagen-induced arthritis

scientific article

Cartilage oligomeric matrix protein induction of chronic arthritis in mice

scientific article published in July 2008

Cartilage oligomeric matrix protein specific antibodies are pathogenic

scientific article published on 20 August 2012

Cartilage-binding antibodies induce pain through immune complex-mediated activation of neurons

scientific article published on 13 June 2019

Characterization of chemically defined poly-N-isopropylacrylamide based copolymeric adjuvants

scientific article published on 4 June 2013

Chemical changes demonstrated in cartilage by synchrotron infrared microspectroscopy in an antibody-induced murine model of rheumatoid arthritis

scientific article published on 01 June 2011

Chemical cross-linking abrogates adjuvant potential of natural polymers

scholarly article in RSC Advances, vol. 4 no. 27, 2014

Chronic active arthritis driven by macrophages without involvement of T cells

scientific article published on 7 March 2018

Chronic development of collagen-induced arthritis is associated with arthritogenic antibodies against specific epitopes on type II collagen

scientific article

Collagen Antibody-Induced Arthritis: A Disease-Relevant Model for Studies of Persistent Joint Pain

Collagen antibody-induced arthritis evokes persistent pain with spinal glial involvement and transient prostaglandin dependency

scientific article

Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells

scientific article

Collagen type II and a thermo-responsive polymer of N-isopropylacrylamide induce arthritis independent of Toll-like receptors: a strong influence by major histocompatibility complex class II and Ncf1 genes

scientific article

Comparative Analysis on Abnormal Methylome of Differentially Expressed Genes and Disease Pathways in the Immune Cells of RA and SLE

scientific article published on 17 May 2021

Complement activation by both classical and alternative pathways is critical for the effector phase of arthritis

scientific article published in April 2004

Correction: A Recombinant Vaccine Effectively Induces C5a-Specific Neutralizing Antibodies and Prevents Arthritis.

scientific article published on 22 January 2011

Crystal structure of an arthritogenic anticollagen immune complex

scientific article

Current Progress in the Development of Zika Virus Vaccines

scientific article published in 2021

Cystatin C influences the autoimmune but not inflammatory response to cartilage type II collagen leading to chronic arthritis development

scientific article published on 28 March 2011

Design and pharmaceutical applications of proteolysis-targeting chimeric molecules

scientific article published on 29 August 2020

Destructive effects of murine arthritogenic antibodies to type II collagen on cartilage explants in vitro

scientific article

Diagnosis of typhoid fever: detection of Salmonella typhi porins-specific antibodies by inhibition ELISA.

scientific article published on November 1993

Do “infectious” prey select for high levels of natural antibodies in tropical pythons?

Dominant suppression of inflammation by glycan-hydrolyzed IgG

scientific article published on 13 May 2013

Early expression of interleukin-12, p40 subunit and IFN-gamma inhibits regression of AK-5 tumor

scientific article published on 01 December 1997

Effects of oestradiol and raloxifene on the induction and effector phases of experimental postmenopausal arthritis and secondary osteoporosis

scientific article published on 19 April 2011

Efficient promotion of collagen antibody induced arthritis (CAIA) using four monoclonal antibodies specific for the major epitopes recognized in both collagen induced arthritis and rheumatoid arthritis

scientific article published in September 2005

Emerging and state of the art hemagglutinin-targeted influenza virus inhibitors

scientific article published on 17 December 2020

Endoglycosidase treatment abrogates IgG arthritogenicity: Importance of IgG glycosylation in arthritis

scientific article published on 01 October 2007

Enhancement of Antibody-Induced Arthritis via Toll-Like Receptor 2 Stimulation Is Regulated by Granulocyte Reactive Oxygen Species

scientific article published on 27 May 2012

Epitope-specific antibody response is controlled by immunoglobulin V H polymorphisms

scientific article

Epitope-specific recognition of type II collagen by rheumatoid arthritis antibodies is shared with recognition by antibodies that are arthritogenic in collagen-induced arthritis in the mouse

scientific article published on 01 September 2002

Ethanol prevents development of destructive arthritis

scientific article

Evaluation of the percentage of peripheral T cells with two different T cell receptor alpha-chains and of their potential role in autoimmunity

scientific article published in June 2001

GLP-1 Receptor Activation Abrogates β-Cell Dysfunction by PKA Cα-Mediated Degradation of Thioredoxin Interacting Protein

scientific article published on 25 October 2019

Genetic control of antibody production during collagen induced arthritis development in heterogeneous stock mice

scholarly article by Michael Förster et al published February 2012 in Annals of the Rheumatic Diseases

Genetic control of antibody production during collagen-induced arthritis development in heterogeneous stock mice

article

Genetic control of tolerance to type II collagen and development of arthritis in an autologous collagen-induced arthritis model

scientific article published in October 2003

Germinal Center B Cells Are Essential for Collagen-Induced Arthritis.

scientific article published on 17 October 2017

Heterogeneous Stock Mice are Susceptible to Encephalomyelitis and Antibody-initiated Arthritis but not to Collagen- and G6PI-induced Arthritis

scientific article published on 01 January 2011

High-resolution mapping of a complex disease, a model for rheumatoid arthritis, using heterogeneous stock mice

article

IL-10-Deficient B10.Q Mice Develop More Severe Collagen-Induced Arthritis, but Are Protected from Arthritis Induced with Anti-Type II Collagen Antibodies

scientific article published on 01 September 2001

IL-4-deficient mice develop less acute but more chronic relapsing collagen-induced arthritis

scientific article published on 01 October 2002

Identification of arthritis promoting non-obese diabetic genes in theCia9locus using different genetic strategies

article

Identification of epistasis through a partial advanced intercross reveals three arthritis loci within the Cia5 QTL in mice.

scientific article

In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012.

scientific article

Incomplete B cell tolerance to cartilage oligomeric matrix protein in mice

scientific article published in September 2013

Increased salt exposure affects both lymphoid and myeloid effector functions, influencing innate-associated disease but not T-cell-associated autoimmunity

scientific article published on 07 March 2018

Induction of arthritis by single monoclonal IgG anti-collagen type II antibodies and enhancement of arthritis in mice lacking inhibitory FcgammaRIIB.

scientific article published in August 2003

Influence of immunopotentiators on the antiporin immunoglobulin G subclass: distribution and protective immunity against murine salmonellosis.

scientific article published in August 1999

Inhibiting the C5-C5a receptor axis

scientific article published on 06 May 2011

Inhibition of dengue viral infection by diasarone-I is associated with 2'O methyltransferase of NS5.

scientific article published on 12 December 2017

Integrated bioprocess for the production and isolation of urokinase from animal cell culture using supermacroporous cryogel matrices

scientific article published on March 2006

Keratinocyte growth factor (KGF) delays the onset of collagen-induced arthritis

scientific article published on 5 September 2012

Macrophage-derived reactive oxygen species protects against autoimmune priming with a defined polymeric adjuvant

scientific article published on 12 October 2015

Macrophages suppress T cell responses and arthritis development in mice by producing reactive oxygen species

scientific article published on October 2007

Mannan induces ROS-regulated, IL-17A-dependent psoriasis arthritis-like disease in mice

scientific article

Methotrexate ameliorates T cell dependent autoimmune arthritis and encephalomyelitis but not antibody induced or fibroblast induced arthritis.

scientific article published on 2 September 2004

Modulation of granulocyte-endothelium interactions by antileukoproteinase: inhibition of anti-type II collagen antibody-induced leukocyte attachment to the synovial endothelium

scientific article published on January 2006

Molecular and Cellular Pathways Contributing to Joint Damage in Rheumatoid Arthritis

scientific article published on 17 March 2020

Monoclonal antibodies against Salmonella porins: generation and characterization

scientific article published on July 1, 1992

Monoclonal antibody production using a new supermacroporous cryogel bioreactor

scientific article

Mouse models for rheumatoid arthritis

scholarly article by Anna-Karin B Lindqvist et al published June 2002 in Trends in Genetics

Nerve conduction velocity is regulated by the inositol polyphosphate-4-phosphatase II gene.

scientific article published on 13 August 2014

Pathogenic antibody recognition of cartilage

scientific article published on 09 June 2009

Pathogenic autoreactive B cells are not negatively selected toward matrix protein collagen II.

scientific article published on 21 September 2011

Phytoestrogens protect joints in collagen induced arthritis by increasing IgG glycosylation and reducing osteoclast activation

scientific article published on 12 March 2020

Polymeric cryogels are biocompatible, and their biodegradation is independent of oxidative radicals

scientific article published on 28 October 2013

Polymorphic estrogen receptor binding site causes Cd2-dependent sex bias in the susceptibility to autoimmune diseases

scientific article published on 22 September 2021

Protective effects of Wang-Bi tablet on bone destruction in collagen-induced arthritis by regulating osteoclast-osteoblast functions

scientific article published on 04 April 2019

Q63, a novel DENV2 RdRp non-nucleoside inhibitor, inhibited DENV2 replication and infection

scientific article published on 25 June 2018

Rabeximod reduces arthritis severity in mice by decreasing activation of inflammatory cells

scientific article

Reactive oxygen species in psoriasis and psoriasis arthritis: relevance to human disease

scientific article published on 20 March 2015

Recent Research on Flavonoids and their Biomedical applications

scientific article published on 13 July 2020

Recent advances in the development of vaccines for chronic inflammatory autoimmune diseases

article

Regulation of autoantibody activity by the IL-23-TH17 axis determines the onset of autoimmune disease

scientific article

Regulatory role of Golgi brefeldin A resistance factor-1 in amyloid precursor protein trafficking, cleavage and Aβ formation

scientific article published on 20 May 2019

Relapsing polychondritis, induced in mice with matrilin 1, is an antibody- and complement-dependent disease

scientific journal article

Role of anti-hinge antibodies in therapeutic cleavage of IgG: response to Drs. Lutz and Fumia

scholarly article by Kutty Selva Nandakumar & Rikard Holmdahl published August 2008 in Trends in Immunology

Role of cytokines in the maintenance of the memory immune response induced by a rat histiocytoma in syngeneic hosts.

scientific article published in September 1998

SNX10 (sorting nexin 10) inhibits colorectal cancer initiation and progression by controlling autophagic degradation of SRC

scientific article published on 04 July 2019

Secretory lysosome targeting and induced secretion of human soluble TNF-alpha receptor in murine hematopoietic cells in vivo as a principle for immunoregulation in inflammation and malignancy.

scientific article

Specific antibody protection of the extracellular cartilage matrix against collagen antibody-induced damage

scientific article published on 01 November 2010

Stimuli-Responsive Polymers as Adjuvants and Carriers for Antigen Delivery

Streptococcal Endo-β--Acetylglucosaminidase Suppresses Antibody-Mediated Inflammation

scientific article published on 16 July 2018

Stromal cells and osteoclasts are responsible for exacerbated collagen-induced arthritis in interferon-β-deficient mice

scientific article published on 01 December 2005

Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis

scientific article

Synthetic polymer as an adjuvant in collagen-induced arthritis

scientific article published on 21 March 2014

System A amino acid transporters regulate glutamine uptake and attenuate antibody-mediated arthritis

scientific article published on 8 September 2015

TLR1/2 Specific Small‐Molecule Agonist Suppresses Leukemia Cancer Cell Growth by Stimulating Cytotoxic T Lymphocytes

scientific article published on 27 March 2019

Targeting IgG in Arthritis: Disease Pathways and Therapeutic Avenues

scientific article published on 28 February 2018

Targeting pattern-recognition receptors to discover new small molecule immune modulators

scientific article published on 8 December 2017

Tatanan A from the Acorus calamus L. root inhibited dengue virus proliferation and infections

scientific article published on 15 March 2018

The autoantibody response to cyclic citrullinated collagen type II peptides in rheumatoid arthritis

scientific article published on 01 September 2019

The crystal structure of the pathogenic collagen type II-specific mouse monoclonal antibody CIIC1 Fab: structure to function analysis

scientific article

The novel small molecule drug Rabeximod is effective in reducing disease severity of mouse models of autoimmune disorders.

scientific article

The plasminogen activator/plasmin system is essential for development of the joint inflammatory phase of collagen type II-induced arthritis

scientific article

The role of collagen antibodies in mediating arthritis

scientific article published on 03 June 2008

The role of collagen antibodies in mediating arthritis

Therapeutic cleavage of IgG: new avenues for treating inflammation

scientific article

Therapeutic effects of artesunate on lupus-prone MRL/lpr mice are dependent on T follicular helper cell differentiation and activation of JAK2-STAT3 signaling pathway

scientific article published on 19 May 2019

Therapeutic vaccination of active arthritis with a glycosylated collagen type II peptide in complex with MHC class II molecules

scientific article published in February 2006

Three-dimensional culture for monoclonal antibody production by hybridoma cells immobilized in macroporous gel particles

scientific article

Two monoclonal antibodies to precisely the same epitope of type II collagen select non-crossreactive phage clones by phage display: implications for autoimmunity and molecular mimicry

scientific article

Type II collagen antibody response is enriched in the synovial fluid of rheumatoid joints and directed to the same major epitopes as in collagen induced arthritis in primates and mice

scientific article

Type II collagen-specific antibodies induce cartilage damage in mice independent of inflammation

scientific article

Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity

scientific article published in January 2006

Vitamin D3 receptor polymorphisms regulate T cells and T cell-dependent inflammatory diseases

scientific article published on 21 September 2020

[1,2,4]Triazolo[1,5-a]pyrimidine derivative (Mol-5) is a new NS5-RdRp inhibitor of DENV2 proliferation and DENV2-induced inflammation

scientific article published on 15 November 2019

Paulina is supported by:

About Paulina

Help