List of works by Alejandro Cabezas-Cruz

A Novel Combined Scientific and Artistic Approach for the Advanced Characterization of Interactomes: The Akirin/Subolesin Model

scientific article published on 08 February 2020

A comparison of the performance of regression models of Amblyomma americanum (L.) (Ixodidae) using life cycle or landscape data from administrative divisions.

scientific article

Anaplasma marginale major surface protein 1a: a marker of strain diversity with implications for control of bovine anaplasmosis

scientific article published on 14 March 2015

Anaplasma phagocytophilum Infection Subverts Carbohydrate Metabolic Pathways in the Tick Vector, Ixodes scapularis

scientific article published on 07 February 2017

Anaplasma phagocytophilum MSP4 and HSP70 Proteins Are Involved in Interactions with Host Cells during Pathogen Infection

scientific article

Anaplasma phagocytophilum Manipulates Host Cell Apoptosis by Different Mechanisms to Establish Infection.

scientific article published on 15 July 2016

Anaplasma phagocytophilum Uses Common Strategies for Infection of Ticks and Vertebrate Hosts

scientific article published on 21 December 2015

Anaplasma phagocytophilum increases the levels of histone modifying enzymes to inhibit cell apoptosis and facilitate pathogen infection in the tick vector Ixodes scapularis.

scientific article published on 28 March 2016

Anaplasma phagocytophilum modifies tick cell microRNA expression and upregulates isc-mir-79 to facilitate infection by targeting the Roundabout protein 2 pathway

scientific article published on 24 June 2019

Anti-Microbiota Vaccine Reduces Avian Malaria Infection Within Mosquito Vectors

scientific article published on 03 March 2022

Anti-Microbiota Vaccines Modulate the Tick Microbiome in a Taxon-Specific Manner

scientific article published on 12 July 2021

Anti-Tick Microbiota Vaccine Impacts Ixodes ricinus Performance during Feeding

scientific article published on 21 November 2020

Antibacterial and antifungal activity of defensins from the Australian paralysis tick, Ixodes holocyclus

scientific article published on 16 August 2019

Antiplasmodial Activity Is an Ancient and Conserved Feature of Tick Defensins.

scientific article published on 24 October 2016

Antiplasmodial activity of tick defensins in a mouse model of malaria

scientific article published on 15 March 2018

Are ticks venomous animals?

scientific article

Assessment of the Safety and Efficacy of an Oral Probiotic-Based Vaccine Against Aspergillus Infection in Captive-Bred Humboldt Penguins (<i>Spheniscus humboldti</i>)

scientific article published on 13 May 2022

Behind Taxonomic Variability: The Functional Redundancy in the Tick Microbiome

scientific article published on 20 November 2020

Bovine ticks harbour a diverse array of microorganisms in Pakistan

scientific article published on 03 January 2020

COVID-19 in the Developing World: Is the Immune Response to α-Gal an Overlooked Factor Mitigating the Severity of Infection?

scientific article published on 12 November 2020

Cancer research meets tick vectors for infectious diseases

scientific article published on October 2014

Characterization of two strains of Anaplasma marginale isolated from cattle in Rio de Janeiro, Brazil, after propagation in tick cell culture.

scientific article

Clinical gamasoidosis and antibody response in two patients infested with Ornithonyssus bursa (Acari: Gamasida: Macronyssidae)

scientific article published on 31 July 2019

Combination of RT-PCR and proteomics for the identification of Crimean-Congo hemorrhagic fever virus in ticks

scientific article published on 12 July 2017

Comparative Genomics of Field Isolates of Mycobacterium bovis and M. caprae Provides Evidence for Possible Correlates with Bacterial Viability and Virulence

scientific article published on 19 November 2015

Complete Genome Sequence of Ehrlichia mineirensis, a Novel Organism Closely Related to Ehrlichia canis with a New Host Association

scientific article

Complete Genome Sequence of an Strain Isolated from Cattle

scientific article published on 11 April 2019

Complete Genome Sequences of Field Isolates of Mycobacterium bovis and Mycobacterium caprae

scientific article published on 25 June 2015

Control of vector-borne infectious diseases by human immunity against α-Gal

scientific article published on 21 April 2016

Defensins from the tick Ixodes scapularis are effective against phytopathogenic fungi and the human bacterial pathogen Listeria grayi.

scientific article

Delayed hypersensitivity reaction to mammalian galactose-α-1,3-galactose (α-Gal) after repeated tick bites in a patient from France

scientific article published on 02 June 2019

Detection and phylogenetic characterization of Theileria spp. and Anaplasma marginale in Rhipicephalus bursa in Portugal

scientific article

Detection of Rickettsia spp. in Rhipicephalus sanguineus (sensu lato) collected from free-roaming dogs in Coahuila state, northern Mexico

scientific article published on 26 March 2019

Development and application of a multiplex TaqMan® real-time qPCR assay for the simultaneous detection of Anaplasma marginale and Theileria annulata and molecular characterization of Anaplasma marginale from cattle in Western Cuba

scientific article published on 16 December 2019

Effect of blood type on anti-α-Gal immunity and the incidence of infectious diseases

scientific article published on 10 March 2017

Efficient Transovarial Transmission of Babesia Spp. in Rhipicephalus microplus Ticks Fed on Water Buffalo (Bubalus bubalis)

scientific article published on 11 April 2020

Ehrlichia minasensis sp. nov., a new species within the genus Ehrlichia isolated from the tick Rhipicephalus microplus

scientific article

Ehrlichia minasensis, an old demon with a new name

scientific article published on 27 March 2019

Environmental and Molecular Drivers of the α-Gal Syndrome

scientific article published on 31 May 2019

Epidemiology and evolution of the genetic variability of Anaplasma marginale in South Africa

scientific article published on 8 July 2014

Epidemiology and genetic diversity of Anaplasma marginale in Zamora-Chinchipe, Ecuador

scientific article published on 21 January 2020

Epidemiology and genetic diversity of Anaplasma ovis in goats in Corsica, France

article

Epigenetic control of gene function in schistosomes: a source of therapeutic targets?

scientific article

Evolutionary Insights into the Tick Hologenome

scientific article published on 19 July 2019

Fast evolutionary rates associated with functional loss in class I glucose transporters of Schistosoma mansoni

scientific article

Fatal cases of bovine anaplasmosis in a herd infected with different Anaplasma marginale genotypes in southern Spain

scientific article published in 2022

First molecular evidence of Babesia caballi and Theileria equi infections in horses in Cuba

scientific article published on 23 July 2018

First report of spotted fever group Rickettsia in Cuba.

scientific article published on 21 June 2016

Flying ticks: anciently evolved associations that constitute a risk of infectious disease spread

scientific article

Functional Evolution of Subolesin/Akirin

scientific article published on 13 November 2018

Functional Redundancy and Ecological Innovation Shape the Circulation of Tick-Transmitted Pathogens

scientific article

Functional and immunological relevance of Anaplasma marginale major surface protein 1a sequence and structural analysis

scientific article

Functional characterization of α-Gal producing lactic acid bacteria with potential probiotic properties

scientific article published on 06 May 2022

Gene expression changes in the salivary glands of Anopheles coluzzii elicited by Plasmodium berghei infection

scientific article

Gut Microbiota Abrogates Anti-α-Gal IgA Response in Lungs and Protects against Experimental Aspergillus Infection in Poultry

scientific article published on 07 June 2020

Hexapod Assassins’ Potion: Venom Composition and Bioactivity from the Eurasian Assassin Bug Rhynocoris iracundus

scientific article published in 2021

High Throughput Sequencing and Network Analysis Disentangle the Microbial Communities of Ticks and Hosts Within and Between Ecosystems

scholarly article by Agustín Estrada-Peña et al published 2018 in Frontiers in cellular and infection microbiology

High co-infection rates of Babesia bovis, Babesia bigemina, and Anaplasma marginale in water buffalo in Western Cuba

scientific article published on 28 January 2019

Histone Methyltransferase DOT1L is Involved in Larval Molting and Second Stage Nymphal Feeding in Ornithodoros Moubata

scientific article published on 01 April 2020

Identification and Characterization of Anaplasma phagocytophilum Proteins Involved in Infection of the Tick Vector, Ixodes scapularis

scientific article (publication date: 2015)

Identification and molecular characterization of spotted fever group rickettsiae in ticks collected from farm ruminants in Lebanon

scientific article published on 12 October 2017

Identification and partial characterisation of new members of the Ixodes ricinus defensin family

scientific article published on 4 March 2014

Identification of Plasmodium falciparum Translation Initiation eIF2β Subunit: Direct Interaction with Protein Phosphatase Type 1

scientific article (publication date: 2016)

Immunity to glycan α-Gal and possibilities for the control of COVID-19

scientific article published on 14 December 2020

Immunity to α-Gal: The Opportunity for Malaria and Tuberculosis Control.

scientific article published on 4 December 2017

Immunity to α-Gal: Toward a Single-Antigen Pan-Vaccine To Control Major Infectious Diseases.

scientific article published on 10 November 2017

In vitro culture and structural differences in the major immunoreactive protein gp36 of geographically distant Ehrlichia canis isolates.

scientific article published on 6 April 2014

In vitro culture of a novel genotype of Ehrlichia sp. from Brazil.

scientific article published on November 2013

Infection of Ixodes spp. tick cells with different Anaplasma phagocytophilum isolates induces the inhibition of apoptotic cell death.

scientific article published on 6 July 2015

Infection of water buffalo in Rio de Janeiro Brazil with Anaplasma marginale strains also reported in cattle.

scientific article published on 19 September 2014

Infection with Toxocara canis Inhibits the Production of IgE Antibodies to α-Gal in Humans: Towards a Conceptual Framework of the Hygiene Hypothesis?

scientific article published on 06 April 2020

Interactions between tick and transmitted pathogens evolved to minimise competition through nested and coherent networks

scientific article

Isolation and Characterization of a Novel Pathogenic Strain of Ehrlichia minasensis

scientific article published on 05 November 2019

Ixodes ricinus defensins attack distantly-related pathogens.

scientific article

Ixodes scapularis Tick Cells Control Anaplasma phagocytophilum Infection by Increasing the Synthesis of Phosphoenolpyruvate from Tyrosine.

scientific article published on 17 August 2017

Low genetic diversity associated with low prevalence of Anaplasma marginale in water buffaloes in Marajó Island, Brazil.

scientific article published on 22 July 2014

Low genetic diversity of Ehrlichia canis associated with high co-infection rates in Rhipicephalus sanguineus (s.l.)

scientific article published on 07 January 2019

Modeling Modulation of the Tick Regulome in Response to for the Identification of New Control Targets

scientific article published on 18 April 2019

Molecular evidence of the reservoir competence of water buffalo (Bubalus bubalis) for Anaplasma marginale in Cuba

scientific article published on 23 June 2018

Molecular identification and characterization of Anaplasma platys and Ehrlichia canis in dogs in Mexico.

scientific article

Molecular identification of spotted fever group Rickettsia in ticks collected from dogs and small ruminants in Greece

scientific article published on 07 June 2019

Molecular survey of Rickettsial organisms in ectoparasites from a dog shelter in Northern Mexico

scientific article published on 17 October 2017

Nested coevolutionary networks shape the ecological relationships of ticks, hosts, and the Lyme disease bacteria of the Borrelia burgdorferi (s.l.) complex

scientific article

Novel immunomodulators from hard ticks selectively reprogramme human dendritic cell responses.

scientific article

Nuclease Tudor-SN Is Involved in Tick dsRNA-Mediated RNA Interference and Feeding but Not in Defense against Flaviviral or Anaplasma phagocytophilum Rickettsial Infection

scientific article published on 17 July 2015

Phyloproteomic and functional analyses do not support a split in the genus Borrelia (phylum Spirochaetes)

scientific article published on 13 February 2019

Prevalence of type I sensitization to alpha-gal in forest service employees and hunters: Is the blood type an overlooked risk factor in epidemiological studies of the α-Gal syndrome?

scientific article published in December 2017

Regulation of the Immune Response to α-Gal and Vector-borne Diseases

scientific article published on October 2015

Remodeling of tick cytoskeleton in response to infection with Anaplasma phagocytophilum.

scientific article

Reservoir and vector evolutionary pressures shaped the adaptation of Borrelia.

scientific article published on 11 April 2018

Resistance of Tick Gut Microbiome to Anti-Tick Vaccines, Pathogen Infection and Antimicrobial Peptides

scientific article published on 22 April 2020

Salivary Prostaglandin E2: Role in Tick-Induced Allergy to Red Meat

scientific article published on 29 March 2017

Schistosome sirtuins as drug targets

scientific article published on January 2015

Sex-Specific Linkages Between Taxonomic and Functional Profiles of Tick Gut Microbiomes

scientific article published on 14 August 2019

Substrate prediction of Ixodes ricinus salivary lipocalins differentially expressed during Borrelia afzelii infection

scientific article

Systems biology of tissue-specific response to Anaplasma phagocytophilum reveals differentiated apoptosis in the tick vector Ixodes scapularis.

scientific article

Targeting a global health problem: Vaccine design and challenges for the control of tick-borne diseases

scientific article

The Drosophila melanogaster antimicrobial peptides Mtk-1 and Mtk-2 are active against the malarial parasite Plasmodium falciparum

scientific article published on 18 April 2019

The alpha-Gal syndrome: new insights into the tick-host conflict and cooperation

scientific article published on 03 April 2019

The genus Anaplasma: new challenges after reclassification.

scientific article

The glycoprotein TRP36 of Ehrlichia sp. UFMG-EV and related cattle pathogen Ehrlichia sp. UFMT-BV evolved from a highly variable clade of E. canis under adaptive diversifying selection

scientific article

The intracellular bacterium Anaplasma phagocytophilum selectively manipulates the levels of vertebrate host proteins in the tick vector Ixodes scapularis

scientific article published on 25 August 2016

The redox metabolic pathways function to limit Anaplasma phagocytophilum infection and multiplication while preserving fitness in tick vector cells

scientific article published on 13 September 2019

Thermostable Keystone Bacteria Maintain the Functional Diversity of the Ixodes scapularis Microbiome Under Heat Stress

scientific article published in 2021

Tick Infestation in Migratory Birds of the Vistula River Valley, Poland

scientific article published in 2022

Tick and Host Derived Compounds Detected in the Cement Complex Substance

scientific article published on 05 April 2020

Tick defensin γ-core reduces Fusarium graminearum growth and abrogates mycotoxins production with high efficiency

scientific article published on 12 April 2021

Tick galactosyltransferases are involved in α-Gal synthesis and play a role during Anaplasma phagocytophilum infection and Ixodes scapularis tick vector development

scientific article published in Scientific Reports

Tick-Host-Pathogen Interactions: Conflict and Cooperation

scientific article

Tick-Pathogen Ensembles: Do Molecular Interactions Lead Ecological Innovation?

scientific article published on 13 March 2017

Tick-Pathogen Interactions and Vector Competence: Identification of Molecular Drivers for Tick-Borne Diseases

scientific article published on 07 April 2017

Tick-Pathogen Interactions: The Metabolic Perspective

scientific article published on 30 January 2019

Tick-borne pathogen detection: what's new?

scientific article published on 9 January 2018

Tick-host conflict: immunoglobulin E antibodies to tick proteins in patients with anaphylaxis to tick bite

scientific article

Ticks and Tick-Borne Diseases in Central America and the Caribbean: A One Health Perspective

scientific article published on 09 October 2021

Ticks and Tick-Borne Diseases in Cuba, Half a Century of Scientific Research

scientific article published on 28 July 2020

Ticks and Tick-Borne Pathogens of the Caribbean: Current Understanding and Future Directions for More Comprehensive Surveillance

scientific article published on 29 November 2017

Towards the integrative analysis of tick microbiome

scientific article published on 01 September 2018

Tribolium castaneum defensins are primarily active against Gram-positive bacteria

scientific article published on 29 October 2015

Ultrastructure of Ehrlichia mineirensis, a new member of the Ehrlichia genus.

scientific article

Understanding the evolutionary structural variability and target specificity of tick salivary Kunitz peptides using next generation transcriptome data.

scientific article

Use of Graph Theory to Characterize Human and Arthropod Vector Cell Protein Response to Infection With

scientific article published on 03 August 2018

Vaccination with Alpha-Gal Protects Against Mycobacterial Infection in the Zebrafish Model of Tuberculosis

scientific article published on 24 April 2020

Vector microbiota manipulation by host antibodies: the forgotten strategy to develop transmission-blocking vaccines

scientific article published in 2022

mRNA export in the apicomplexan parasite Toxoplasma gondii: emerging divergent components of a crucial pathway

scientific article

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