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List of works by Douglas S Darling

3,5,3'-triiodothyronine (T3) receptor-auxiliary protein (TRAP) binds DNA and forms heterodimers with the T3 receptor

scientific article published on January 1991

3,5,3'-triiodothyronine receptor auxiliary protein (TRAP) enhances receptor binding by interactions within the thyroid hormone response element

scientific article published on January 1991

A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors.

scientific article

A nuclear factor that enhances binding of thyroid hormone receptors to thyroid hormone response elements.

scientific article published on February 1990

A systems biology approach identifies a regulatory network in parotid acinar cell terminal differentiation

scientific article published on 30 April 2015

A zinc finger homeodomain transcription factor binds specific thyroid hormone response elements

scientific article

An N-terminal hydrophobic peak is the sorting signal of regulated secretory proteins

scientific article published on 01 March 1995

Analysis of Zfhx1a mutant mice reveals palatal shelf contact-independent medial edge epithelial differentiation during palate fusion.

scientific article published on 10 May 2008

Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance.

scientific article published on 17 April 2017

Basal and thyroid hormone receptor auxiliary protein-enhanced binding of thyroid hormone receptor isoforms to native thyroid hormone response elements

scientific article published on December 1991

Beta 1,4 N-acetylgalactosaminyltransferase (GM2/GD2/GA2 synthase) forms homodimers in the endoplasmic reticulum: a strategy to test for dimerization of Golgi membrane proteins

scientific article published on 01 October 1997

Cell Type–Specific Transcriptome Analysis Reveals a Major Role for Zeb1 and miR-200b in Mouse Inner Ear Morphogenesis ⬇️

scientific article published on September 29, 2011

Characterization and tissue expression of multiple triiodothyronine receptor-auxiliary proteins and their relationship to the retinoid X-receptors

scientific article published on 01 September 1993

Cloned beta 1,4 N-acetylgalactosaminyltransferase synthesizes GA2 as well as gangliosides GM2 and GD2. GM3 synthesis has priority over GA2 synthesis for utilization of lactosylceramide substrate in vivo

scientific article published on 01 November 1994

Cloned beta 1,4N-acetylgalactosaminyltransferase: subcellular localization and formation of disulfide bonded species

scientific article published on 01 April 1996

Comparison of thyroid hormone binding to heptic nuclei of the rat and a teleost (Oncorhynchus kisutch).

scientific article

Control of myosin heavy chain expression in cardiac hypertrophy

scientific article published on 01 January 1987

Developmental and functional evidence of a role for Zfhep in neural cell development ⬇️

scientific article published on November 30, 2001

Different dimerization activities of alpha and beta thyroid hormone receptor isoforms

scientific article published on 01 May 1993

Different thresholds of ZEB1 are required for Ras-mediated tumour initiation and metastasis

scientific article published in December 2014

Disulfide bonds of GM2 synthase homodimers. Antiparallel orientation of the catalytic domains.

scientific article

EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness.

scientific article published on 04 September 2012

Effects of triiodothyronine and propylthiouracil on thyroid function and smoltification of coho salmon (Oncorhynchus kisutch)

scientific article published on 01 October 1987

Erratum: Different thresholds of ZEB1 are required for Ras-mediated tumour initiation and metastasis

scientific article published in Nature Communications

Estrogen enhances gonadotropin-releasing hormone-stimulated transcription of the luteinizing hormone subunit promoters via altered expression of stimulatory and suppressive transcription factors

scientific article

Expression of Zfhep/deltaEF1 protein in palate, neural progenitors, and differentiated neurons

scientific journal article

Expression of multiple thyroid hormone receptor mRNAs in human oocytes, cumulus cells, and granulosa cells

scientific article

Helicobacter pylori infection in people who are intellectually and developmentally disabled: a review

scientific article published on July 2007

Identification of a rat c-erbA alpha-related protein which binds deoxyribonucleic acid but does not bind thyroid hormone

scientific article published on October 1988

Identification of a thyroid hormone receptor that is pituitary-specific

scientific article published in April 1989

Isolation and Characterization of a cDNA Encoding a Chicken β Thyroid Hormone Receptor ⬇️

scientific article published on April 1, 1991

Isoproterenol increases sorting of parotid gland cargo proteins to the basolateral pathway. ⬇️

scientific article

MUC1 splice variants in human ocular surface tissues: possible differences between dry eye patients and normal controls

scientific article

Mesenchymal cell remodeling during mouse secondary palate reorientation

scientific article

Metastatic progression of prostate cancer and e-cadherin regulation by zeb1 and SRC family kinases.

scientific article

Model discrimination in dynamic molecular systems: application to parotid de-differentiation network.

scientific article published on July 2013

N- and C-terminal domains direct cell type-specific sorting of chromogranin A to secretory granules

scientific article published on 01 March 2000

Novel ZEB1 expression in bladder tumorigenesis ⬇️

scientific article published on August 24, 2010

Nuclear receptors for L-triiodothyronine in trout erythrocytes

scientific article published on 01 January 1987

Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor.

scientific article

Pancreastatin, a chromogranin A-derived peptide, inhibits transcription of the parathyroid hormone and chromogranin A genes and decreases the stability of the respective messenger ribonucleic acids in parathyroid cells in culture

scientific article published on 01 March 1994

Parotid secretory granules: crossroads of secretory pathways and protein storage.

scientific article

Parotid secretory protein binds phosphatidylinositol (3,4) bisphosphate

scientific article

Phosphorylation Regulates Functions of ZEB1 Transcription Factor

scientific article

Porphyromonas gingivalis initiates a mesenchymal-like transition through ZEB1 in gingival epithelial cells.

scientific article

Re: The genetics of male infertility

scientific article published on 01 August 1997

T3-activation of the rat growth hormone gene is inhibited by a zinc finger/homeodomain protein

scientific journal article

The DXD motif is required for GM2 synthase activity but is not critical for nucleotide binding

scientific article published in March 2001

The EMT transcription factor ZEB2 promotes proliferation of primary and metastatic melanoma while suppressing an invasive, mesenchymal-like phenotype

scientific article published on 05 June 2020

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

scientific article (publication date: December 2009)

The ZFHX1A gene is differentially autoregulated by its isoforms

scientific article

The transcription factor ZEB1 is aberrantly expressed in aggressive uterine cancers

scientific article

The zinc finger transcription factor ZFHX1A is linked to cell proliferation by Rb-E2F1.

scientific article

Thyroid hormone receptor mutations that interfere with transcriptional activation also interfere with receptor interaction with a nuclear protein

scientific article published on 01 January 1991

Thyroid hormone regulation of the rat glycoprotein hormone alpha-subunit gene promoter activity

scientific article published on 01 April 1989

Thyroid hormone regulation of thyrotropin gene expression.

scientific article

Triiodothyronine (T3) decreases binding to DNA by T3-receptor homodimers but not receptor-auxiliary protein heterodimers

scientific article published on February 1992

Two soluble glycosyltransferases glycosylate less efficiently in vivo than their membrane bound counterparts

scientific article published in August 1998

Use of multiple time points to model parotid differentiation

scientific article published on 20 May 2015

ZEB1 Promotes invasiveness of colorectal carcinoma cells through the opposing regulation of uPA and PAI-1.

scientific article published on 22 January 2013

ZEB1 Regulates Multiple Oncogenic Components Involved in Uveal Melanoma Progression.

scientific article

ZEB1 and TCF4 reciprocally modulate their transcriptional activities to regulate Wnt target gene expression

scientific article published on 21 September 2015

ZEB1 expression in type I vs type II endometrial cancers: a marker of aggressive disease.

scientific article

ZEB1 imposes a temporary stage-dependent inhibition of muscle gene expression and differentiation via CtBP-mediated transcriptional repression

scientific article published on 22 January 2013

ZEB1-induced tumourigenesis requires senescence inhibition via activation of DKK1/mutant p53/Mdm2/CtBP and repression of macroH2A1.

scientific article published on 13 December 2016

Zeb1 links epithelial-mesenchymal transition and cellular senescence

scientific journal article

Zeb1 mutant mice as a model of posterior corneal dystrophy

scientific journal article

Zeb1 represses Mitf and regulates pigment synthesis, cell proliferation, and epithelial morphology

scientific article published on 10 June 2009

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