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List of works by Francesca Pentimalli

'Paternal' guidance

(Truly) on and off at the flick of a switch

44 A miRNA EXPRESSION PROFILING IDENTIFIES MIR-145 AS A KEY PLAYER IN HUMAN MALIGNANT PLEURAL MESOTHELIOMA

A 3.4-kbp transcript of ZNF331 is solely expressed in follicular thyroid adenomas.

scientific article

A blast of HOTAIR silences distant chromatin

A pathway to complexity

A pilot study on the impact of known drug-drug interactions in cancer patients

scientific article

A truncated HMGA1 gene induces proliferation of the 3T3-L1 pre-adipocytic cells: a model of human lipomas

scientific article published on 11 September 2003

A useful combination

ATP-noncompetitive CDK inhibitors for cancer therapy: an overview

scientific article

Abrogating G₂/M checkpoint through WEE1 inhibition in combination with chemotherapy as a promising therapeutic approach for mesothelioma

scientific article published on 14 January 2014

Alterations of the tumor suppressor gene Parkin in non-small cell lung cancer

scientific article published on April 2004

Alternative routes

Antineoplastic activity of povidone-iodine on different mesothelioma cell lines: results of in vitro study

scientific article

Antitumor activity of new pyrazolo[3,4-d]pyrimidine SRC kinase inhibitors in Burkitt lymphoma cell lines and its enhancement by WEE1 inhibition

scientific article

Antitumoral potential, antioxidant activity and carotenoid content of two Southern Italy tomato cultivars extracts: San Marzano and Corbarino

scientific article published on 10 May 2017

Autophagy in disease: hunger for translation

scientific article published on 17 February 2019

BCL2: a 30-year tale of life, death and much more to come

scientific article published on 10 November 2017

BMPs on the brain

Beneficial loss

Beneficial loss

Beyond the usual suspects

Beyond the usual suspects

Branching defects

Breaking and entering

CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancy

scientific article

Calretinin Immunoreactivity in the Human Testis Throughout Fetal Life.

scientific article published on 19 December 2016

Cancer, immunity and inflammation. Report from the CDD Cambridge Conferences 2018 and 2019

scientific article published on 22 October 2019

Cell death pathologies: targeting death pathways and the immune system for cancer therapy

scientific article published on 19 December 2018

Complete Darwin on the web

article by Francesca Pentimalli published December 2006 in Nature Reviews Genetics

Correction: P53-regulated miR-320a targets PDL1 and is downregulated in malignant mesothelioma

scientific article published on 16 October 2020

Depletion of the RNA binding protein HNRNPD impairs homologous recombination by inhibiting DNA-end resection and inducing R-loop accumulation

scientific article published on 01 May 2019

Detection of high mobility group I HMGI(Y) protein in the diagnosis of thyroid tumors: HMGI(Y) expression represents a potential diagnostic indicator of carcinoma ⬇️

scientific article published on September 15, 1998

Directed in vivo angiogenesis assay and the study of systemic neoangiogenesis in cancer

scientific article published on 06 January 2011

Downregulation and aberrant promoter methylation of p16INK4A: a possible novel heritable susceptibility marker to retinoblastoma

scientific article published in April 2010

Expanding the range

Fishing for clues

Going to any length

HLA-B*44 and C*01 Prevalence Correlates with Covid19 Spreading across Italy

scientific article published on 23 July 2020

HMGA1 protein expression sensitizes cells to cisplatin-induced cell death

scientific article published on October 2005

HMGA1 protein is a novel target of the ATM kinase

scientific article published on 8 September 2008

HMGA1 protein over-expression is a frequent feature of epithelial ovarian carcinomas

scientific article published on 9 May 2003

HMGA1 protein overexpression in human breast carcinomas: correlation with ErbB2 expression

scientific article

HUR protects NONO from degradation by mir320, which is induced by p53 upon UV irradiation

scientific article published on November 2016

Haploinsufficiency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice

scientific article published in March 2006

Helping homologues to find their partners

High mobility group HMGI(Y) protein expression in human colorectal hyperplastic and neoplastic diseases

scientific article published in January 2001

High prevalence of RET/PTC rearrangements in Ukrainian and Belarussian post-Chernobyl thyroid papillary carcinomas: a strong correlation between RET/PTC3 and the solid-follicular variant

scientific article published on 01 November 1999

High-mobility-group A1 (HMGA1) proteins down-regulate the expression of the recombination activating gene 2 (RAG2).

scientific article published on July 2005

Homeobox genes: eyeing the clock

article

Homeostasis model assessment to detect insulin resistance and identify patients at high risk of breast cancer development: National Cancer Institute of Naples experience

scientific article published on 14 March 2013

Identification of the genes up- and down-regulated by the high mobility group A1 (HMGA1) proteins: tissue specificity of the HMGA1-dependent gene regulation

scientific article published on August 2004

Inducing the uptake of the deadly executioner in cancer cells.

scientific article

Insertional mutagenesis and development of malignancies induced by integrating gene delivery systems: implications for the design of safer gene-based interventions in patients

scientific article published on May 2009

Involvement of H4(D10S170) protein in ATM-dependent response to DNA damage.

scientific article

Let's suppress tumours

Let-7d miRNA Shows Both Antioncogenic and Oncogenic Functions in Osteosarcoma-Derived 3AB-OS Cancer Stem Cells

scientific article published on 17 December 2015

Loss of Hmga1 gene function affects embryonic stem cell lympho-hematopoietic differentiation

scientific article published on 17 June 2003

Mass spectrometry-based proteomics: the road to lung cancer biomarker discovery

scientific article

Metabolic syndrome affects breast cancer risk in postmenopausal women: National Cancer Institute of Naples experience

scientific article published on 15 December 2010

MicroRNA-29b-1 impairs in vitro cell proliferation, self‑renewal and chemoresistance of human osteosarcoma 3AB-OS cancer stem cells

scientific article published on 22 August 2014

MicroRNAs: unicellular organisms also have their share

Modeling human osteosarcoma in mice through 3AB-OS cancer stem cell xenografts

scientific article published in November 2012

More frequent and more mature

article

NONO regulates the intra-S-phase checkpoint in response to UV radiation.

scientific article

NONO ubiquitination is mediated by FBW7 and GSK3 β via a degron lost upon chromosomal rearrangement in cancer

scientific article published on 18 November 2017

Negative Regulation of BRCA1 Gene Expression by HMGA1 Proteins Accounts for the Reduced BRCA1 Protein Levels in Sporadic Breast Carcinoma

scientific article

New pyrazolo-[3,4-d]-pyrimidine derivative Src kinase inhibitors lead to cell cycle arrest and tumor growth reduction of human medulloblastoma cells

scientific article

New pyrazolo[3,4-d]pyrimidine SRC inhibitors induce apoptosis in mesothelioma cell lines through p27 nuclear stabilization

scientific article

On the trail of transcription factors

Overexpressed cyclin D3 contributes to retaining the growth inhibitor p27 in the cytoplasm of thyroid tumor cells

scientific article

P53-regulated miR-320a targets PDL1 and is downregulated in malignant mesothelioma

scientific article published on 14 September 2020

Paclitaxel-releasing mesenchymal stromal cells inhibit in vitro proliferation of human mesothelioma cells

scientific article published on 30 January 2017

Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27

scientific article

Peptides or small molecules? Different approaches to develop more effective CDK inhibitors.

scientific article

Pharmacological Inhibition of WEE1 Potentiates the Antitumoral Effect of the dl922-947 Oncolytic Virus in Malignant Mesothelioma Cell Lines

scientific article published on 04 October 2020

Pharmacological targeting of p53 through RITA is an effective antitumoral strategy for malignant pleural mesothelioma

scientific article published on 17 December 2013

Predicting breast cancer outcome: Traditional prognosticators still on center stage

scientific article published on 11 January 2010

RBL2/p130 is a direct AKT target and is required to induce apoptosis upon AKT inhibition in lung cancer and mesothelioma cell lines

scientific article published on 2 April 2018

RET activation and clinicopathologic features in poorly differentiated thyroid tumors

scientific article published in January 2002

RET expression in papillary thyroid cancer from patients irradiated in childhood for benign conditions.

scientific article published in August 2002

Retraction: FRA-1 Expression in Hyperplastic and Neoplastic Thyroid Diseases

scientific article published on 01 April 2019

Retraction: Haploinsufficiency of the Hmga1 Gene Causes Cardiac Hypertrophy and Myelo-Lymphoproliferative Disorders in Mice

scientific article published on 01 December 2018

SRC Family Kinase Inhibition in Ewing Sarcoma Cells Induces p38 MAP Kinase-Mediated Cytotoxicity and Reduces Cell Migration.

scientific article published on 02 April 2016

SRC family kinase (SFK) inhibition reduces rhabdomyosarcoma cell growth in vitro and in vivo and triggers p38 MAP kinase-mediated differentiation

scientific article published in May 2015

SRC family kinase inhibition through a new pyrazolo[3,4-d]pyrimidine derivative as a feasible approach for glioblastoma treatment

scientific article published on May 2015

Setting the pace: three's company

Shifting the balance

Shifting the balance

Suppression of HMGA2 protein synthesis could be a tool for the therapy of well differentiated liposarcomas overexpressing HMGA2 ⬇️

scientific article published on November 1, 2003

Suppressive role exerted by microRNA-29b-1-5p in triple negative breast cancer through SPIN1 regulation

scientific article

Targeted therapy based on p53 reactivation reduces both glioblastoma cell growth and resistance to temozolomide

scientific article published on 16 April 2019

The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene

scientific article

The Oncolytic Virus dl922-947 Triggers Immunogenic Cell Death in Mesothelioma and Reduces Xenograft Growth

scientific article published on 12 July 2019

The RET/PTC oncogene is frequently activated in oncocytic thyroid tumors (Hurthle cell adenomas and carcinomas), but not in oncocytic hyperplastic lesions

scientific article published on 01 January 2002

The antiretroviral nucleoside analogue Abacavir reduces cell growth and promotes differentiation of human medulloblastoma cells

scientific article published on July 2009

The burden of breast cancer in Italy: mastectomies and quadrantectomies performed between 2001 and 2008 based on nationwide hospital discharge records

scientific article published on 20 November 2012

The dark side of p27

The homeodomain-interacting protein kinase 2 gene is expressed late in embryogenesis and preferentially in retina, muscle, and neural tissues

scientific article

Therapy of human pancreatic carcinoma based on suppression of HMGA1 protein synthesis in preclinical models

scientific article published in September 2004

Tracking the 2009 H1N1 influenza virus in the Italian region Campania

scientific article published on July 2012

Transcription and translation get together

Transcriptional profile of Ki-Ras-induced transformation of thyroid cells

scientific article

Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas.

scientific article published in May 2005

Translating RB1 predictive value in clinical cancer therapy: Are we there yet?

scientific article published on 07 June 2019

Unleashing regenerative potential

Updates from the TP53 universe

scientific article

Variation patterns

Viral hijacking

scientific article published in 2006

pRb2/p130 localizes to the cytoplasm in diffuse gastric cancer

scientific article published in April 2015

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