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List of works by Juliette Legler

An Integrated Approach to Assess the Role of Chemical Exposure in Obesity ⬇️

scientific article published on June 1, 2013

An in vitro/in vivo screening assay as a sensitive tool to assess endocrine disruptive activity in surface water

scientific article published on 16 November 2006

An integrated assessment of estrogenic contamination and biological effects in the aquatic environment of The Netherlands

scientific article published in April 2005

Anthropogenic and naturally produced brominated substances in Baltic herring (Clupea harengus membras) from two sites in the Baltic Sea.

scientific article published on 21 November 2015

Are brominated flame retardants endocrine disruptors?

scientific article

BIOMONITORING OF ESTROGENIC EXPOSURE AND IDENTIFICATION OF RESPONSIBLE COMPOUNDS IN BREAM FROM DUTCH SURFACE WATERS

scientific article published on 01 May 2007

Biological Validation of a Sample Preparation Method for ER-CALUX Bioanalysis of Estrogenic Activity in Sediment Using Mixtures of Xeno-Estrogens

scientific article published on 01 April 2006

Biological measurement of estrogenic activity in urine and bile conjugates with the in vitro ER-CALUX reporter gene assay.

scientific article

Birth weight and prenatal exposure to polychlorinated biphenyls (PCBs) and dichlorodiphenyldichloroethylene (DDE): a meta-analysis within 12 European Birth Cohorts

scientific article published on 13 October 2011

Burden of disease and costs of exposure to endocrine disrupting chemicals in the European Union: an updated analysis

scientific article

Changes in Neurotransmitter Profiles during Early Zebrafish (Danio rerio) Development and after Pesticide Exposure

scientific article published on 11 February 2016

Chemical-activated luciferase gene expression (CALUX): a novel in vitro bioassay for Ah receptor active compounds in sediments and pore water

scientific article published on September 1996

Combined Transcriptomics Analysis for Classification of Adverse Effects As a Potential End Point in Effect Based Screening

scientific article published on 2 November 2015

Comparability of behavioural assays using zebrafish larvae to assess neurotoxicity.

scientific article

Comparison of in vivo and in vitro reporter gene assays for short-term screening of estrogenic activity

scientific article published in October 2002

Compound- and sex-specific effects on programming of energy and immune homeostasis in adult C57BL/6JxFVB mice after perinatal TCDD and PCB 153.

scientific article published on 25 September 2015

Comprehensive two-dimensional liquid chromatography coupled to high resolution time of flight mass spectrometry for chemical characterization of sewage treatment plant effluents

scientific article published on 31 December 2014

Detection of estrogenic activity in sediment-associated compounds using in vitro reporter gene assays.

scientific article

Detection of estrogenic potency in wastewater and surface water with three in vitro bioassays

scientific article published in January 2002

Detection of oestrogenic activity of steroids present during mammalian gestation using oestrogen receptor alpha- and oestrogen receptor beta-specific in vitro assays

scientific article published on September 2002

Development of a polydimethylsiloxane film-based passive dosing method in the in vitro DR-CALUX® assay

scientific article published on 10 February 2011

Development of a stably transfected estrogen receptor-mediated luciferase reporter gene assay in the human T47D breast cancer cell line

scientific article published on March 1999

Developmental toxicity and endocrine disrupting potency of 4-azapyrene, benzo[b]fluorene and retene in the zebrafish Danio rerio

scientific article published on 20 November 2011

Differential DNA methylation at conserved non-genic elements and evidence for transgenerational inheritance following developmental exposure to mono(2-ethylhexyl) phthalate and 5-azacytidine in zebrafish

scientific article

Disruption of oxidative phosphorylation (OXPHOS) by hydroxylated polybrominated diphenyl ethers (OH-PBDEs) present in the marine environment.

scientific article published on 25 November 2014

Dithiocarbamates are teratogenic to developing zebrafish through inhibition of lysyl oxidase activity

scientific article published on 4 January 2010

Dithiocarbamates induce craniofacial abnormalities and downregulate sox9a during zebrafish development

scientific article published on 7 June 2010

Dynamics of DNA hydroxymethylation in zebrafish.

scientific article published on 9 March 2015

Effect-directed analysis of municipal landfill soil reveals novel developmental toxicants in the zebrafish Danio rerio

scientific article published on 12 September 2011

Effects of endocrine disrupting chemicals on in vitro global DNA methylation and adipocyte differentiation ⬇️

scientific article published on April 18, 2013

Epigenetics: An emerging field in environmental toxicology ⬇️

scientific article published on April 1, 2010

Estimating burden and disease costs of exposure to endocrine-disrupting chemicals in the European union

scientific article

Estrogenic and dioxin-like compounds in sediment from Zierikzee harbour identified with CALUX assay-directed fractionation combined with one and two dimensional gas chromatography analyses

scientific article published on 12 July 2006

Estrogenic and esterase-inhibiting potency in rainwater in relation to pesticide concentrations, sampling season and location

scientific article

Estrogenic endpoints in fish early life-stage tests: luciferase and vitellogenin induction in estrogen-responsive transgenic zebrafish

scientific article published in January 2006

Expert opinion on toxicity profiling--report from a NORMAN expert group meeting

scientific article

First year growth in relation to prenatal exposure to endocrine disruptors - a Dutch prospective cohort study

scientific article

Formation of estrogenic metabolites of benzo[a]pyrene and chrysene by cytochrome P450 activity and their combined and supra-maximal estrogenic activity.

scientific article published on January 2005

Functional environmental genomics of a municipal landfill soil.

scientific article published on 16 May 2012

Identification of estrogenic compounds in fish bile using bioassay-directed fractionation

scientific article published in December 2004

In Vitro Assay Shows That PCB Metabolites Completely Saturate Thyroid Hormone Transport Capacity in Blood of Wild Polar Bears (Ursus maritimus)

scientific article published on 01 April 2010

In vitro biomonitoring in polar extracts of solid phase matrices reveals the presence of unknown compounds with estrogenic activity

scientific article published in February 2003

In vitro profiling of the endocrine-disrupting potency of brominated flame retardants.

scientific article published on 6 April 2006

Intra- and interlaboratory calibration of the DR CALUX bioassay for the analysis of dioxins and dioxin-like chemicals in sediments.

scientific article

LInking EDCs in maternal Nutrition to Child health (LINC study) - protocol for prospective cohort to study early life exposure to environmental chemicals and child health

scientific article

Liver DNA methylation analysis in adult female C57BL/6JxFVB mice following perinatal exposure to bisphenol A.

scientific article published on 17 October 2014

Lysyl oxidase-like 3b is critical for cartilage maturation during zebrafish craniofacial development.

scientific article

Microarray analysis reveals a mechanism of phenolic polybrominated diphenylether toxicity in zebrafish.

scientific article published in March 2008

Multimode sensors as new tools for molecular recognition of testosterone, dihydrotestosterone and estradiol in children's saliva

scientific article published on 01 January 2015

Neurodevelopmental retardation, as assessed clinically and with magnetoencephalography and electroencephalography, associated with perinatal dioxin exposure

scientific article

OECD validation study to assess intra- and inter-laboratory reproducibility of the zebrafish embryo toxicity test for acute aquatic toxicity testing

scientific article published on 27 May 2014

Obesity, diabetes, and associated costs of exposure to endocrine-disrupting chemicals in the European Union

scientific article

Optimization and prevalidation of the in vitro ERalpha CALUX method to test estrogenic and antiestrogenic activity of compounds

scientific article

Parma consensus statement on metabolic disruptors

scientific article published on 20 June 2015

Pattern recognition of estradiol, testosterone and dihydrotestosterone in children's saliva samples using stochastic microsensors

scientific article

Prenatal and Postnatal Exposure to Persistent Organic Pollutants and Infant Growth: A Pooled Analysis of Seven European Birth Cohorts

scientific article published on 6 March 2015

Prenatal exposure to endocrine disrupting chemicals and birth weight-A prospective cohort study

scientific article published on 25 November 2015

Prenatal exposure to endocrine disrupting chemicals in relation to thyroid hormone levels in infants - a Dutch prospective cohort study

scientific article

Programming of metabolic effects in C57BL/6JxFVB mice by exposure to bisphenol A during gestation and lactation

scientific article published on 13 April 2014

Programming of metabolic effects in C57BL/6JxFVB mice by in utero and lactational exposure to perfluorooctanoic acid

scientific article published on April 2015

Recombinational micro-evolution of functionally different metallothionein promoter alleles from Orchesella cincta

scientific article

Sample preparation method for the ER-CALUX bioassay screening of (xeno-)estrogenic activity in sediment extracts

scientific article

The OBELIX project: early life exposure to endocrine disruptors and obesity

scientific article published on 4 May 2011

The Role of Epigenetics in the Latent Effects of Early Life Exposure to Obesogenic Endocrine Disrupting Chemicals

scientific article (publication date: October 2015)

The Virtual Human Platform for Safety Assessment (VHP4Safety) project: Next generation chemical safety assessment based on human data

scientific article published in January 2024

The zebrafish embryo model in toxicology and teratology, September 2–3, 2010, Karlsruhe, Germany

scientific article published in May 2011

Toxicity profiling: An integrated effect-based tool for site-specific sediment quality assessment

scientific article

Toxicological profiling of sediments using in vitro bioassays, with emphasis on endocrine disruption

scientific article published in January 2004

Transcriptional and epigenetic mechanisms underlying enhanced in vitro adipocyte differentiation by the brominated flame retardant BDE-47.

scientific article published on 11 March 2014

Zebrafish as a Model to Study the Role of Peroxisome Proliferating-Activated Receptors in Adipogenesis and Obesity

scientific article

Zebrafish as a model to study the role of DNA methylation in environmental toxicology.

scientific article

Zebrafish embryos as a screen for DNA methylation modifications after compound exposure.

scientific article published on 19 December 2015

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