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List of works by Resat Cinar

Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

scientific article

Alcohol Binge-Induced Cardiovascular Dysfunction Involves Endocannabinoid-CB1-R Signaling

scientific article published on 23 September 2019

Bleomycin Induces Drug Efflux in Lungs. A Pitfall for Pharmacological Studies of Pulmonary Fibrosis

scientific article published on 01 February 2020

CB1 receptor-independent actions of SR141716 on G-protein signaling: coapplication with the mu-opioid agonist Tyr-D-Ala-Gly-(NMe)Phe-Gly-ol unmasks novel, pertussis toxin-insensitive opioid signaling in mu-opioid receptor-Chinese hamster ovary cells

scientific article published on 15 May 2009

Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy

scientific article published on 7 February 2012

Cannabinoid CB1 receptor overactivity contributes to the pathogenesis of idiopathic pulmonary fibrosis

scientific article

Cannabinoid receptor 1 promotes hepatocellular carcinoma initiation and progression through multiple mechanisms

scientific article published on 17 February 2015

Cannabinoid receptor signaling regulates liver development and metabolism

scientific article published on February 2016

Cannabinoid-1 Receptor Antagonism Improves Glycemic Control and Increases Energy Expenditure via Sirt1/mTORC2 and AMPK Signaling

scientific article published on 06 March 2019

Cannabinoid-1 receptor deletion in podocytes mitigates both glomerular and tubular dysfunction in a mouse model of diabetic nephropathy

scientific article published on 6 November 2017

Characterization of heterogeneous redox responses in hepatocellular carcinoma patients using network analysis.

scientific article published on 31 December 2018

Chronic alcohol produces neuroadaptations to prime dorsal striatal learning

scientific article published on 19 August 2013

Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity

scientific article published on 12 June 2012

Crystal Structure of the Human Cannabinoid Receptor CB2

scientific article published on 10 January 2019

Decreasing CB1 receptor signaling in Kupffer cells improves insulin sensitivity in obese mice

scientific article published in September 2017

Design, Synthesis, and Biological Evaluation of Novel, Non-Brain-Penetrant, Hybrid Cannabinoid CB1R Inverse Agonist/Inducible Nitric Oxide Synthase (iNOS) Inhibitors for the Treatment of Liver Fibrosis.

scientific article published on 13 January 2017

Developmental Role of Macrophage Cannabinoid-1 Receptor Signaling in Type 2 Diabetes

scientific article published on 12 January 2017

Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice

scientific article published on 11 May 2020

Disruption of renal arginine metabolism promotes kidney injury in hepatorenal syndrome

scientific article published on 6 April 2018

Dual inhibition of cannabinoid CB1 receptor and inducible NOS attenuates obesity-induced chronic kidney disease

scientific article published on 27 December 2019

Endocannabinoids in liver disease

scientific article

Feasibility Evaluation of Myocardial Cannabinoid Type 1 Receptor Imaging in Obesity: A Translational Approach.

scientific article published in February 2018

Fluoxetine Facilitates Fear Extinction Through Amygdala Endocannabinoids

scientific article

Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasing de novo synthesis of long-chain ceramides

scientific article

Hybrid inhibitor of peripheral cannabinoid-1 receptors and inducible nitric oxide synthase mitigates liver fibrosis

scientific article published on July 2016

Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver

scientific article

Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects

scientific article

Interplay of Liver-Heart Inflammatory Axis and Cannabinoid 2 Receptor Signaling in an Experimental Model of Hepatic Cardiomyopathy

scientific article published on 24 January 2020

Lack of regulatory changes of µ-opioid receptors by 14-methoxymetopon treatment in rat brain. Further evidence for functional selectivity

scientific article published on January 2013

Ligand-specific regulation of the endogenous mu-opioid receptor by chronic treatment with mu-opioid peptide agonists

scientific article published on 24 November 2013

Mice lacking GPR3 receptors display late-onset obese phenotype due to impaired thermogenic function in brown adipose tissue

scientific article

Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase

scientific article

Network analyses identify liver-specific targets for treating liver diseases

scientific article published on 21 August 2017

Overactive cannabinoid 1 receptor in podocytes drives type 2 diabetic nephropathy

scientific article

Peripheral cannabinoid-1 receptor blockade restores hypothalamic leptin signaling

scientific article published on 24 June 2017

Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistance

scientific article

Proximal Tubular Cannabinoid-1 Receptor Regulates Obesity-Induced CKD.

scientific article published on 31 August 2017

Reciprocal inhibition of G-protein signaling is induced by CB(1) cannabinoid and GABA(B) receptor interactions in rat hippocampal membranes

scientific article

Role of adiponectin in the metabolic effects of cannabinoid type 1 receptor blockade in mice with diet-induced obesity

scientific article published on 31 December 2013

Stratification of Hepatocellular Carcinoma Patients Based on Acetate Utilization

scientific article published on 19 November 2015

Structural Basis of Species-Dependent Differential Affinity of 6-Alkoxy-5-Aryl-3-Pyridinecarboxamide Cannabinoid-1 Receptor Antagonists

scientific article published on 26 May 2015

Synthesis of 13 C6 -labeled, dual-target inhibitor of cannabinoid-1 receptor (CB1 R) and inducible nitric oxide synthase (iNOS)

scientific article published on 23 May 2018

Synthesis of S-2-((S)-3-(4-chlorophenyl)-N'-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamido)-3-(methyl-d3 )butanamide-d5 , octadeuterated JD5037.

scientific article published on 25 May 2017

Synthetic cannabinoids induce acute lung inflammation via cannabinoid receptor 1 activation

scientific article published on 01 July 2020

Targeting the endocannabinoid/CB1 receptor system for treating obesity in Prader-Willi syndrome

scientific article published on 22 October 2016

The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity

scientific article published on 23 September 2015

β-Caryophyllene protects against alcoholic steatohepatitis by attenuating inflammation and metabolic dysregulation in mice

scientific article published on 20 January 2017

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