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List of works by Raymond P. Donnelly

A Mutation in the SH2 domain of STAT2 prolongs tyrosine phosphorylation of STAT1 and promotes type I IFN-induced apoptosis

scientific article published on 18 April 2007

A comparison of interferon gene expression induced by influenza A virus infection of human airway epithelial cells from two different donors

scientific article published on 16 February 2019

A novel role for IL-22R1 as a driver of inflammation

scientific article

A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus

scientific article

Alpha and lambda interferon together mediate suppression of CD4 T cells induced by respiratory syncytial virus

scientific article

Amino Acids in Hemagglutinin Antigenic Site B Determine Antigenic and Receptor Binding Differences between A(H3N2)v and Ancestral Seasonal H3N2 Influenza Viruses

scientific article published on 2 November 2016

An Overview of Cytokines and Cytokine Antagonists as Therapeutic Agents

scientific article published on 01 December 2009

An essential role for IFN-β in the induction of IFN-stimulated gene expression by LPS in macrophages

scientific article

Characterization of the mouse IFN-lambda ligand-receptor system: IFN-lambdas exhibit antitumor activity against B16 melanoma

scientific article (publication date: 15 April 2006)

Conformational changes mediate interleukin-10 receptor 2 (IL-10R2) binding to IL-10 and assembly of the signaling complex

scientific article published on 18 September 2006

Differential responses by human respiratory epithelial cell lines to respiratory syncytial virus reflect distinct patterns of infection control

scientific article

Distinct and overlapping genomic profiles and antiviral effects of Interferon-λ and -α on HCV-infected and noninfected hepatoma cells.

scientific article

Effect of influenza H1N1 neuraminidase V116A and I117V mutations on NA activity and sensitivity to NA inhibitors

scientific article published on 19 June 2019

Effect of isoprinosine on sialylation of interleukin-2

scientific article published on 01 April 1986

Generation and characterization of interferon-lambda 1-resistant H1N1 influenza A viruses.

scientific article

Human interleukin-19 and its receptor: a potential role in the induction of Th2 responses

scientific article published on May 2004

Hurdles and leaps for protein therapeutics

scientific article

IFN-gamma down-regulates Secretoglobin 3A1 gene expression

scientific article published on 09 January 2009

IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex

scientific article

IFN-γ priming of monocytes enhances LPS-induced TNF production by augmenting both transcription and mRNA stability

article

IFN-λ4 Attenuates Antiviral Responses by Enhancing Negative Regulation of IFN Signaling.

scientific article

IFN-λ4: the paradoxical new member of the interferon lambda family

scientific article

IL-4 engagement of the type I IL-4 receptor complex enhances mouse eosinophil migration to eotaxin-1 in vitro

scientific article

Identification and quantification of defective virus genomes in high throughput sequencing data using DVG-profiler, a novel post-sequence alignment processing algorithm.

scientific article

Immunosuppression induced by staphylococcal enterotoxin B

scientific article published on 01 September 1982

Impact of Influenza A Virus Infection on the Proteomes of Human Bronchoepithelial Cells from Different Donors

scientific article published on 26 July 2017

In vitro anti-influenza A activity of interferon (IFN)-λ1 combined with IFN-β or oseltamivir carboxylate.

scientific article

Influenza A virus hemagglutinin mutations associated with use of neuraminidase inhibitors correlate with decreased inhibition by anti-influenza antibodies

scientific article published on 29 November 2019

Influenza virus NS1 protein mutations at position 171 impact innate interferon responses by respiratory epithelial cells

scientific article

Inhibition of interleukin-2-induced T-cell proliferation by sera from patients with the acquired immune deficiency syndrome.

scientific article published in January 1986

Inhibitors of prostaglandin synthesis block the induction of staphylococcal enterotoxin B-activated T-suppressor cells

scientific article published on 01 October 1983

Interferon-lambda (IFN-λ) induces signal transduction and gene expression in human hepatocytes, but not in lymphocytes or monocytes

scientific article published on 20 December 2012

Interferon-lambda and therapy for chronic hepatitis C virus infection

scientific article

Interferon-lambda: a new addition to an old family

scientific article

Interferons inhibit activation of STAT6 by interleukin 4 in human monocytes by inducing SOCS-1 gene expression

scientific article published on September 1999

Interleukin-10 induces uteroglobin-related protein (UGRP) 1 gene expression in lung epithelial cells through homeodomain transcription factor T/EBP/NKX2.1

scientific article

Interleukin-12 Differentially Regulates Expression of IFN-γ and Interleukin-2 in Human T Lymphoblasts

scientific article published on 01 October 2000

Interleukin-26: an IL-10-related cytokine produced by Th17 cells

scientific article

Isoprinosine effects on interleukin-1 production in acquired immune deficiency syndrome (AIDS)

scientific article published on 01 January 1986

Kinetic analysis of the immunopotentiating effect of the hypoxanthine analogue, NPT-15392, on the interleukin-2 production potential of human lymphocytes

scientific article published on 01 January 1986

Laninamivir-Interferon-λ1 Combination Treatment Promotes Resistance by Influenza A Virus More Rapidly Than Laninamivir Alone

scientific article published on 11 May 2020

Leishmania donovani-induced expression of suppressor of cytokine signaling 3 in human macrophages: a novel mechanism for intracellular parasite suppression of activation

scientific article

Meeting Overview: Interferon Lambda-Disease Impact and Therapeutic Potential

scientific article published on 17 April 2019

Oncostatin M regulates secretoglobin 3A1 and 3A2 expression in a bidirectional manner

scientific article published on 31 October 2008

Regulation of the dephosphorylation of Stat6. Participation of Tyr-713 in the interleukin-4 receptor alpha, the tyrosine phosphatase SHP-1, and the proteasome

scientific article published on 28 November 2002

Resistance to IFN-alpha-induced apoptosis is linked to a loss of STAT2

scientific article

Suppression of B-cell and T-cell responses by the prostaglandin-induced T-cell-derived suppressor (PITS)

article

Suppression of B-cell and T-cell responses by the prostaglandin-induced T-cell-derived suppressors (PITS) — III. Production of PITSβ factors from T-cell hybridomas

article

Suppressor of cytokine signaling-1 is an IL-4-inducible gene in macrophages and feedback inhibits IL-4 signaling

scientific article published on 9 November 2006

The IFN-λ Family (IL-28/29)

The Interleukin-13 Receptor-α1 Chain Is Essential for Induction of the Alternative Macrophage Activation Pathway by IL-13 but Not IL-4.

scientific article

The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain

scientific article

The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes.

scientific article

The use of plant lectins to regulate H1N1 influenza A virus receptor binding activity.

scientific article published on 9 April 2018

Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity

scientific article published on 13 October 2008

Type III IFNs are produced by and stimulate human plasmacytoid dendritic cells

scientific article published on 13 August 2012

Unique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor alpha1 chain

scientific article published on 09 December 2007

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