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List of works by Dirk Schwarzer

A Multiplexed NMR-Reporter Approach to Measure Cellular Kinase and Phosphatase Activities in Real-Time.

scientific article published on 15 May 2015

A miniaturized readout strategy for endogenous histone deacetylase activity.

scientific article published on June 2015

Accessibility of different histone H3-binding domains of UHRF1 is allosterically regulated by phosphatidylinositol 5-phosphate

scientific article published on 8 May 2014

Analysis of phosphorylation-dependent protein-protein interactions of histone h3.

scientific article published on 5 November 2014

Asymmetric Disulfanylbenzamides as Irreversible and Selective Inhibitors of Staphylococcus aureus Sortase A

scientific article published on 02 March 2020

Cellular stability of serotonin N-acetyltransferase conferred by phosphonodifluoromethylene alanine (Pfa) substitution for Ser-205.

scientific article published on 4 January 2005

Chemical biology: Chromatin chemistry goes cellular

scientific article published on 01 May 2015

Chemical tools in chromatin research.

scientific article published on October 2010

Chemo-enzymatic three-fragment assembly of semisynthetic proteins

scientific article published on 09 January 2014

Chemoselective ligation and modification strategies for peptides and proteins.

scientific article published on January 2008

Chloroplast Acetyltransferase NSI Is Required for State Transitions in Arabidopsis thaliana

scientific article published on 02 July 2018

Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells

scientific article

DRP1 interacts directly with BAX to induce its activation and apoptosis

scientific article published on 13 January 2022

Decreasing the ring size of a cyclic nonribosomal peptide antibiotic by in-frame module deletion in the biosynthetic genes

scientific article published in September 2002

Differential contribution of the repeats to heparin binding of HBHA, a major adhesin of Mycobacterium tuberculosis

scientific article

Directed evolution of sortase A mutants with altered substrate selectivity profiles

scientific article

Dual lysine and N-terminal acetyltransferases reveal the complexity underpinning protein acetylation

scientific article published on 01 July 2020

Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin.

scientific article published on 19 April 2016

Ebony, a novel nonribosomal peptide synthetase for beta-alanine conjugation with biogenic amines in Drosophila

scientific article published on 4 August 2003

Exploring the impact of different thioesterase domains for the design of hybrid peptide synthetases

scientific article published on 01 October 2001

Facile synthesis of colorimetric histone deacetylase substrates

scientific article published on 01 October 2012

Generality of peptide cyclization catalyzed by isolated thioesterase domains of nonribosomal peptide synthetases.

scientific article published in June 2001

In-Cell NMR in Mammalian Cells: Part 1

scientific article published on 01 January 2012

Interaction studies and alanine scanning analysis of a semi-synthetic split intein reveal thiazoline ring formation from an intermediate of the protein splicing reaction

scientific article published on 14 July 2008

Interrogating Substrate Selectivity and Composition of Endogenous Histone Deacetylase Complexes with Chemical Probes.

scientific article published on 14 December 2015

Investigating Deformylase and Deacylase Activity of Mammalian and Bacterial Sirtuins

scientific article published on 05 February 2016

Lysine acetylome profiling uncovers novel histone deacetylase substrate proteins in Arabidopsis

scientific article published on 23 October 2017

Methylation of lysine 9 in histone H3 directs alternative modes of highly dynamic interaction of heterochromatin protein hHP1β with the nucleosome

scientific article published on 19 July 2012

Modulations of DNA Contacts by Linker Histones and Post-translational Modifications Determine the Mobility and Modifiability of Nucleosomal H3 Tails

scientific article published on 12 January 2016

Multimodular biocatalysts for natural product assembly

scientific article published in March 2001

Mutational analysis of a type II thioesterase associated with nonribosomal peptide synthesis

scientific article published in April 2004

NMR Profiling of Histone Deacetylase and Acetyl-transferase Activities in Real Time

scientific article published on 07 March 2011

Negative regulation of a protein tyrosine phosphatase by tyrosine phosphorylation

scientific article published on 01 April 2006

Peptide-Based 2-Aminophenylamide Probes for Targeting Endogenous Class I Histone Deacetylase Complexes

scientific article published on 26 September 2019

Phosphorylation of histone H3 Ser10 establishes a hierarchy for subsequent intramolecular modification events

scientific article

Probing Chromatin-modifying Enzymes with Chemical Tools.

scientific article published on 4 February 2016

Probing intein-catalyzed thioester formation by unnatural amino acid substitutions in the active site

scientific article published on 28 December 2011

Probing the acetylation code of histone H4.

scientific article

Probing the recognition of post-translational modifications by combining sortase-mediated ligation and phage-assisted selection.

scientific article

Probing the structure-activity relationship of endogenous histone deacetylase complexes with immobilized peptide-inhibitors

scientific article published on 12 April 2016

Protein kinase structure and function analysis with chemical tools.

scientific article

Protein semisynthesis and expressed protein ligation: chasing a protein's tail

scientific article

Quantitative assessment of protein interaction with methyl-lysine analogues by hybrid computational and experimental approaches

scientific article published on 18 October 2011

Regeneration of misprimed nonribosomal peptide synthetases by type II thioesterases.

scientific article

Semisynthesis and initial characterization of sortase A mutants containing selenocysteine and homocysteine

scientific article published on 30 March 2015

Semisynthesis and optimization of G protein-coupled receptor mimics

scientific article published on 4 August 2014

Semisynthesis of proteins using split inteins.

scientific article

Simultaneous detection of protein phosphorylation and acetylation by high-resolution NMR spectroscopy

scientific article published on October 2010

Site-specific mapping and time-resolved monitoring of lysine methylation by high-resolution NMR spectroscopy.

scientific article published on 27 April 2012

Sortase-mediated ligations for the site-specific modification of proteins

scientific article

Structural basis for the cyclization of the lipopeptide antibiotic surfactin by the thioesterase domain SrfTE

scientific article

Synthetic histone code.

scientific article published on 05 August 2015

TRIM24 links a non-canonical histone signature to breast cancer

scientific article

The Alzheimer's disease related tau protein as a new target for chemical protein engineering

scientific article published on 9 January 2012

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