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List of works by Kevin M. Shakesheff

A Detailed Assessment of Varying Ejection Rate on Delivery Efficiency of Mesenchymal Stem Cells Using Narrow-Bore Needles.

scientific article published on 29 January 2016

A biomaterials approach to influence stem cell fate in injectable cell-based therapies

scientific article published on 21 February 2018

A comparison of polymer and polymer-hydroxyapatite composite tissue engineered scaffolds for use in bone regeneration. An in vitro and in vivo study

scientific article published on 5 September 2013

A comparison of the adhesion of mammalian cells and Staphylococcus epidermidis on fibronectin-modified polymer surfaces

scientific article published on August 2001

A mathematical model of liver cell aggregation in vitro.

scientific article published on 18 December 2008

A novel biotinylated degradable polymer for cell-interactive applications

scientific article

A novel technique for the production of electrospun scaffolds with tailored three-dimensional micro-patterns employing additive manufacturing.

scientific article published on 11 April 2014

A simple method for the simultaneous isolation of stellate cells and hepatocytes from rat liver tissue

scientific article published in June 2003

A thermoresponsive and magnetic colloid for 3D cell expansion and reconfiguration

scientific article published on 29 November 2014

A thermoreversible hydrogel as a biosynthetic bandage for corneal wound repair.

scientific article

Accelerated formation of multicellular 3-D structures by cell-to-cell cross-linking

scientific article published on August 2007

Accelerating protein release from microparticles for regenerative medicine applications

scientific article published on 21 February 2013

Adenoviral BMP-2 gene transfer in mesenchymal stem cells: in vitro and in vivo bone formation on biodegradable polymer scaffolds

scientific article published on March 2002

Adjuvant chemotherapy for brain tumors delivered via a novel intra-cavity moldable polymer matrix

scientific article (publication date: 2013)

Aggregation promotes cell viability, proliferation, and differentiation in an in vitro model of injection cell therapy.

scientific article published on 20 September 2011

Alpha-MSH inhibits inflammatory signalling in Schwann cells.

scientific article published in March 2004

An analysis of polymer type and chain length for use as a biological composite graft extender in impaction bone grafting: A mechanical and biocompatibility study

scientific article published on 15 June 2012

An automated fabrication strategy to create patterned tubular architectures at cell and tissue scales.

scientific article published on 14 April 2015

Analysis of sintered polymer scaffolds using concomitant synchrotron computed tomography and in situ mechanical testing

scientific article

Attachment of stem cells to scaffold particles for intra-cerebral transplantation

scientific article published on 17 September 2009

Biocompatibility and enhanced osteogenic differentiation of human mesenchymal stem cells in response to surface engineered poly(D,L-lactic-co-glycolic acid) microparticles

scientific article published on 20 December 2013

Biocompatibility and osteogenic potential of human fetal femur-derived cells on surface selective laser sintered scaffolds

scientific article

Biofilm eradication with biodegradable modified-release antibiotic pellets: a potential treatment for glue ear.

scientific article published in October 2012

Bioprinting Using Mechanically Robust Core-Shell Cell-Laden Hydrogel Strands.

scientific article published on 3 February 2017

Bone extracellular matrix hydrogel enhances osteogenic differentiation of C2C12 myoblasts and mouse primary calvarial cells

scientific article

Calcium-binding phospholipids as a coating material for implant osteointegration

scientific article published in April 2006

Cell adhesion and mechanical properties of a flexible scaffold for cardiac tissue engineering.

scientific article published on 26 February 2007

Cell and protein compatible 3D bioprinting of mechanically strong constructs for bone repair

scientific article

Cell-type-specific adhesion onto polymer surfaces from mixed cell populations.

scientific article

Characterisation of the surface structure of 3D printed scaffolds for cell infiltration and surgical suturing.

scientific article published in March 2016

Chemical and spatial analysis of protein loaded PLGA microspheres for drug delivery applications

article

Combination of Injectable Multiple Growth Factor–Releasing Scaffolds and Cell Therapy as an Advanced Modality to Enhance Tissue Neovascularization

scientific article published on 05 August 2010

Combined hydrogels that switch human pluripotent stem cells from self-renewal to differentiation

scientific article

Controlled embryoid body formation via surface modification and avidin-biotin cross-linking.

scientific article published on December 2009

Controlled release of BMP-2 from a sintered polymer scaffold enhances bone repair in a mouse calvarial defect model ⬇️

scientific article published on June 8, 2012

Controlling protein release from scaffolds using polymer blends and composites

scientific article published on 18 July 2007

Creating biomimetic micro-environments with synthetic polymer-peptide hybrid molecules.

scientific article published in January 1998

Decellularized bone extracellular matrix and human dental pulp stem cells as a construct for bone regeneration

scientific article

Delivery of definable number of drug or growth factor loaded poly(DL-lactic acid-co-glycolic acid) microparticles within human embryonic stem cell derived aggregates

scientific article published on 14 March 2013

Dental pulp stem cells: function, isolation and applications in regenerative medicine

scientific article published on 21 May 2014

Development of a bioluminescent ATP assay to quantify mammalian and bacterial cell number from a mixed population.

scientific article published on January 2003

Development of a porous poly(DL‐lactic acid‐co‐glycolic acid)‐based scaffold for mastoid air‐cell regeneration ⬇️

scientific article published on May 13, 2013

Development of a slow non-viral DNA release system from PDLLA scaffolds fabricated using a supercritical CO2 technique

scientific article published in October 2007

Direct fabrication as a patient-targeted therapeutic in a clinical environment.

scientific article published on January 2012

Direct three-dimensional printing of polymeric scaffolds with nanofibrous topography.

scientific article published on 13 December 2017

Directed Differentiation of Human Embryonic Stem Cells to Interrogate the Cardiac Gene Regulatory Network ⬇️

scientific article published on June 21, 2011

Drug delivery to the ear.

scientific article published in January 2013

Dynamics of anterior-posterior axis formation in the developing mouse embryo

scientific article

Early gene regulation of osteogenesis in embryonic stem cells.

scientific article

Efficient assessment of the utility of immortalized Fa2N-4 cells for cytochrome P450 (CYP) induction studies using multiplex quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) and substrate cassette methodologies.

scientific article

Encapsulation of RIN-m5F cells within Ba2+ cross-linked alginate beads affects proliferation and insulin secretion

scientific article published on September 2006

Engineering an in-vitro model of rodent cartilage.

scientific article published on 16 March 2012

Engineering embryonic stem-cell aggregation allows an enhanced osteogenic differentiation in vitro.

scientific article published on August 2010

Engineering tissue alternatives to animals: applying tissue engineering to basic research and safety testing.

scientific article published on July 2009

Evaluation of a thermoresponsive polycaprolactone scaffold for in vitro three-dimensional stem cell differentiation.

scientific article published on 11 November 2014

Evaluation of nanostructure and microstructure of bone regenerated by BMP-2-porous scaffolds.

scientific article published on 11 March 2015

Evaluation of skeletal tissue repair, part 1: assessment of novel growth-factor-releasing hydrogels in an ex vivo chick femur defect model

scientific article published on 14 June 2014

Evaluation of skeletal tissue repair, part 2: enhancement of skeletal tissue repair through dual-growth-factor-releasing hydrogels within an ex vivo chick femur defect model

scientific article published on 4 June 2014

Extracellular matrix-derived hydrogels for dental stem cell delivery

scientific article published on 16 September 2016

Formulations for delivery of therapeutic proteins.

scientific article published on 11 September 2008

Gelatin embedding for the preparation of thermoreversible or delicate scaffolds for histological analysis.

scientific article published on 4 June 2013

Gelation of microsphere dispersions using a thermally-responsive graft polymer.

scientific article

Gene therapy used for tissue engineering applications.

scientific article published on March 2007

Growth factor release from tissue engineering scaffolds.

scientific article

Highly efficient delivery of functional cargoes by the synergistic effect of GAG binding motifs and cell-penetrating peptides.

scientific article

Highly efficient intracellular transduction in three-dimensional gradients for programming cell fate.

scientific article

Hollow colloidosomes prepared using accelerated solvent evaporation.

scientific article published on 28 October 2013

Human osteoprogenitor growth and differentiation on synthetic biodegradable structures after surface modification

scientific article published in December 2001

Hydrogels derived from demineralized and decellularized bone extracellular matrix.

scientific article published on 25 April 2013

Image-based characterization of foamed polymeric tissue scaffolds

scientific article published on 3 March 2008

Immunoselection and adenoviral genetic modulation of human osteoprogenitors: in vivo bone formation on PLA scaffold

scientific article published in November 2002

Improved delivery of PLGA microparticles and microparticle-cell scaffolds in clinical needle gauges using modified viscosity formulations

scientific article published on 16 May 2018

In Vivo Assessment of Bone Regeneration in Alginate/Bone ECM Hydrogels with Incorporated Skeletal Stem Cells and Single Growth Factors

scientific article published on 16 December 2015

In situ gelling hydrogels incorporating microparticles as drug delivery carriers for regenerative medicine

scientific article published in September 2008

In situ monitoring of 3D in vitro cell aggregation using an optical imaging system.

scientific article published on May 2008

In vitro assessment of cell penetration into porous hydroxyapatite scaffolds with a central aligned channel

scientific article published on November 2004

Incorporation of proteins within alginate fibre-based scaffolds using a post-fabrication entrapment method

scientific article published on July 2006

Induction of human osteoprogenitor chemotaxis, proliferation, differentiation, and bone formation by osteoblast stimulating factor-1/pleiotrophin: osteoconductive biomimetic scaffolds for tissue engineering

scientific article published on January 2003

Injectable and porous PLGA microspheres that form highly porous scaffolds at body temperature.

scientific article published on 23 August 2014

Interactions of 3T3 fibroblasts and endothelial cells with defined pore features

scientific article published on August 2002

Interconnectivity analysis of supercritical CO₂-foamed scaffolds

scientific article published on 15 September 2010

Laminin and fibronectin treatment leads to generation of dendritic cells with superior endocytic capacity

scientific article

Leukocyte-inspired biodegradable particles that selectively and avidly adhere to inflamed endothelium in vitro and in vivo.

scientific article

Liver tissue engineering: a role for co-culture systems in modifying hepatocyte function and viability

scientific article published on June 2001

Long-term culture of functional liver tissue: three-dimensional coculture of primary hepatocytes and stellate cells

scientific article published on 01 June 2003

Maggots and wound healing: an investigation of the effects of secretions from Lucilia sericata larvae upon interactions between human dermal fibroblasts and extracellular matrix components

scientific article published in May 2003

Mammalian cell survival and processing in supercritical CO(2)

scholarly article

Manipulation of live mouse embryonic stem cells using holographic optical tweezers

article by Jonathan Leach et al published 20 February 2009 in Journal of Modern Optics

Mannan binding lectin-associated serine protease 1 is induced by hepatitis C virus infection and activates human hepatic stellate cells.

scientific article published on November 2013

Mathematical modelling of engineered tissue growth using a multiphase porous flow mixture theory

scientific article published on 7 February 2006

Microparticles for Sustained Growth Factor Delivery in the Regeneration of Critically-Sized Segmental Tibial Bone Defects ⬇️

scientific article published on 31 March 2016

Microparticles for controlled growth differentiation factor 6 delivery to direct adipose stem cell-based nucleus pulposus regeneration

scientific article published on 19 June 2019

Neo-vascularization of the stroke cavity by implantation of human neural stem cells on VEGF-releasing PLGA microparticles.

scientific article published on 18 July 2012

Neuralization of mouse embryonic stem cells in alginate hydrogels under retinoic acid and SAG treatment.

scientific article published on August 2015

Non-local models for the formation of hepatocyte-stellate cell aggregates

scientific article published on 13 August 2010

Novel surface entrapment process for the incorporation of bioactive molecules within preformed alginate fibers.

scientific article published on March 2005

Odontogenic Differentiation of Human Dental Pulp Stem Cells on Hydrogel Scaffolds Derived from Decellularized Bone Extracellular Matrix and Collagen Type I.

scientific article published on 16 February 2016

PLGA/PEG-hydrogel composite scaffolds with controllable mechanical properties

scientific article published on 29 January 2013

Photo-cross-linked hydrogels from thermoresponsive PEGMEMA-PPGMA-EGDMA copolymers containing multiple methacrylate groups: mechanical property, swelling, protein release, and cytotoxicity.

scientific article published in October 2009

Plasticization and spraying of poly (DL-lactic acid) using supercritical carbon dioxide: control of particle size

scientific article published in April 2004

Poly(D,L-lactide-co-glycolide) dispersions containing pluronics: from particle preparation to temperature-triggered aggregation.

scientific article published on 21 June 2008

Poly(L-lysine)-GRGDS as a biomimetic surface modifier for poly(lactic acid).

scientific article published in April 2001

Polymeric systems for controlled drug release

scientific article published on 01 November 1999

Post-Modified Polypeptides with UCST-Type Behavior for Control of Cell Attachment in Physiological Conditions

scientific article published on 9 January 2018

Precision assembly of complex cellular microenvironments using holographic optical tweezers

scientific article published on 26 February 2015

Printing patterns of biospecifically-adsorbed protein.

scientific article

Promotion of human dermal fibroblast migration, matrix remodelling and modification of fibroblast morphology within a novel 3D model by Lucilia sericata larval secretions

scientific article published in June 2006

Putting the fizz into chemistry: applications of supercritical carbon dioxide in tissue engineering, drug delivery and synthesis of novel block copolymers.

scientific article published on June 2007

Relating the phagocytosis of microparticles by alveolar macrophages to surface chemistry: the effect of 1,2-dipalmitoylphosphatidylcholine.

scientific article

Remotely Activated Mechanotransduction via Magnetic Nanoparticles Promotes Mineralization Synergistically With Bone Morphogenetic Protein 2: Applications for Injectable Cell Therapy.

scientific article published on 22 September 2014

Scaffold for tissue engineering fabricated by non-isothermal supercritical carbon dioxide foaming of a highly crystalline polyester.

scientific article published on 18 July 2009

Scaffolds containing growth factors and extracellular matrix induce hepatocyte proliferation and cell migration in normal and regenerating rat liver.

scientific article published on 15 September 2010

Scaffolds for liver tissue engineering.

scientific article

Serum protein layers on parylene-C and silicon oxide: effect on cell adhesion ⬇️

scientific article published on 16 December 2014

Spatial Confinement of Neurite Regrowth from Dorsal Root Ganglia within Nonporous Microconduits

scientific article published on 01 April 2003

Supercritical CO2 fluid-foaming of polymers to increase porosity: a method to improve the mechanical and biocompatibility characteristics for use as a potential alternative to allografts in impaction bone grafting?

scientific article published on 24 January 2012

Supercritical carbon dioxide generated vascular endothelial growth factor encapsulated poly(DL-lactic acid) scaffolds induce angiogenesis in vitro

scientific article published on 9 November 2006

Supercritical carbon dioxide: putting the fizz into biomaterials

scientific article

Surface engineering of living myoblasts via selective periodate oxidation.

scientific article published on March 2003

Surface modification of PdlLGA microspheres with gelatine methacrylate: Evaluation of adsorption, entrapment, and oxygen plasma treatment approaches

scientific article

Surgical delivery of drug releasing poly(lactic-co-glycolic acid)/poly(ethylene glycol) paste with in vivo effects against glioblastoma

scientific article published on October 2014

Synthesis and characterisation of a degradable poly(lactic acid)-poly(ethylene glycol) copolymer with biotinylated end groups.

scientific article published in January 2001

Synthesis and characterization of novel poly[(organo)phosphazenes] with cell-adhesive side groups

scientific article published on 29 March 2007

The application of human bone marrow stromal cells and poly(dl-lactic acid) as a biological bone graft extender in impaction bone grafting.

scientific article published on 5 May 2008

The biology of equine mesenchymal stem cells: phenotypic characterization, cell surface markers and multilineage differentiation

scientific article published on January 2012

The effect of anisotropic architecture on cell and tissue infiltration into tissue engineering scaffolds.

scientific article published in September 2006

The effect of delivery via narrow-bore needles on mesenchymal cells.

scientific article published in January 2009

The effect of injection using narrow-bore needles on mammalian cells: administration and formulation considerations for cell therapies

scientific article published on 26 January 2015

The effect of mesenchymal populations and vascular endothelial growth factor delivered from biodegradable polymer scaffolds on bone formation.

scientific article

The effect of processing variables on morphological and mechanical properties of supercritical CO2 foamed scaffolds for tissue engineering

scientific article published on 02 August 2011

The effect of the delivery of vascular endothelial growth factor and bone morphogenic protein-2 to osteoprogenitor cell populations on bone formation

scientific article published on 18 November 2009

The effect of three-dimensional co-culture of hepatocytes and hepatic stellate cells on key hepatocyte functions in vitro

scientific article published in January 2005

The effects of 1α, 25-dihydroxyvitamin D3 and transforming growth factor-β3 on bone development in an ex vivo organotypic culture system of embryonic chick femora

scientific article published on 2 April 2015

The influence of dispersant concentration on the pore morphology of hydroxyapatite ceramics for bone tissue engineering

scientific article published in March 2005

The osteogenic response of mesenchymal stem cells to an injectable PLGA bone regeneration system

scientific article

The production of protein-loaded microparticles by supercritical fluid enhanced mixing and spraying

scientific article published on 01 January 2005

The scale-up of a tissue engineered porous hydroxyapatite polymer composite scaffold for use in bone repair: An ovine femoral condyle defect study

scientific article published on 23 July 2014

The use of SIMS, XPS and in situ AFM to probe the acid catalysed hydrolysis of poly(orthoesters) ⬇️

scientific article published on August 1, 1998

Thermally triggered assembly of cationic graft copolymers containing 2-(2-methoxyethoxy)ethyl methacrylate side chains.

scientific article

Thermally-triggered gelation of PLGA dispersions: towards an injectable colloidal cell delivery system

scientific article published on 22 December 2009

Thermoresponsive and photocrosslinkable PEGMEMA-PPGMA-EGDMA copolymers from a one-step ATRP synthesis

scientific article

Three-Dimensional Bioactive and Biodegradable Scaffolds Fabricated by Surface-Selective Laser Sintering

scientific article

Time-lapsed imaging for in-process evaluation of supercritical fluid processing of tissue engineering scaffolds

scientific article published in July 2009

Tissue engineering in the development of replacement technologies.

scientific article published on January 2012

Tissue engineering: strategies, stem cells and scaffolds

scientific article

Tissue growth in a rotating bioreactor. Part I: mechanical stability

scientific article

Ultrasonic monitoring of foamed polymeric tissue scaffold fabrication

scientific article published on 5 April 2008

Uniform cell colonization of porous 3-D scaffolds achieved using radial control of surface chemistry

scientific article

Zonal release of proteins within tissue engineering scaffolds.

scientific article published on 22 November 2006

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