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List of works by Gerben Bouma

A partial down-regulation of WASP is sufficient to inhibit podosome formation in dendritic cells

scientific article published on 15 December 2005

An increased MRP8/14 expression and adhesion, but a decreased migration towards proinflammatory chemokines of type 1 diabetes monocytes

scientific article published on 01 September 2005

B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice.

scientific article published in February 2012

Brain-derived human immunodeficiency virus-1 Tat exerts differential effects on LTR transactivation and neuroimmune activation

scientific article published on April 2007

CCL20 neutralization by a monoclonal antibody in healthy subjects selectively inhibits recruitment of CCR6+ cells in an experimental suction blister.

scientific article published on 11 March 2017

Cells with dendritic cell morphology and immunophenotype, binuclear morphology, and immunosuppressive function in dendritic cell cultures

scientific article published on 08 October 2011

Cytoskeletal remodeling mediated by WASp in dendritic cells is necessary for normal immune synapse formation and T-cell priming

scientific article published on 20 June 2011

Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells

scientific article published on 18 July 2016

Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse

scholarly article by Chiara Beilin et al published 17 October 2018 in Wellcome Open Research

Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse

article published in 2018

Diabetes-prone NOD mice show an expanded subpopulation of mature circulating monocytes, which preferentially develop into macrophage-like cells in vitro.

scientific article

Disease-associated missense mutations in the EVH1 domain disrupt intrinsic WASp function causing dysregulated actin dynamics and impaired dendritic cell migration

scientific article

Evidence for an enhanced adhesion of DC to fibronectin and a role of CCL19 and CCL21 in the accumulation of DC around the pre-diabetic islets in NOD mice

scientific article published on 01 August 2005

Exacerbated experimental arthritis in Wiskott-Aldrich syndrome protein deficiency: modulatory role of regulatory B cells

scientific article

Functional gap junctions accumulate at the immunological synapse and contribute to T cell activation

scientific article

Genetic variants associated with neutrophil function in aggressive periodontitis and healthy controls

scientific article published in April 2010

Immune complex disease in a chronic monkey study with a humanised, therapeutic antibody against CCL20 is associated with complement-containing drug aggregates

scientific article published on 23 April 2020

Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1.

scientific article

Impaired T-cell priming in vivo resulting from dysfunction of WASp-deficient dendritic cells

scientific article published on 02 August 2007

Impaired neutrophil migration and phagocytosis in IRAK-4 deficiency

scientific article

Improvement of migratory defects in a murine model of Wiskott-Aldrich syndrome gene therapy

scientific article

Increased serum levels of MRP-8/14 in type 1 diabetes induce an increased expression of CD11b and an enhanced adhesion of circulating monocytes to fibronectin.

scientific article

Migratory and antigen presentation functions of IFN-producing killer dendritic cells.

scientific article published on 4 August 2009

NOD mice have a severely impaired ability to recruit leukocytes into sites of inflammation

scientific article published in January 2005

Nonintegrating lentivector vaccines stimulate prolonged T-cell and antibody responses and are effective in tumor therapy

scientific article published on 28 January 2009

Phosphorylation of WASp is a key regulator of activity and stability in vivo

scientific article published on September 2009

Recent advances in the understanding of genetic defects of neutrophil number and function

scientific article published on 31 August 2010

Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiency

scientific article

Stable gene transfer to muscle using non-integrating lentiviral vectors

scientific article published on 14 August 2007

The Wiskott-Aldrich syndrome: The actin cytoskeleton and immune cell function

scientific article

WASp-dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts.

scientific article

Wiskott-Aldrich Syndrome: Immunodeficiency resulting from defective cell migration and impaired immunostimulatory activation

scientific article published on 22 July 2009

Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis

scientific article published on 07 August 2008