List of works - Vincent Aucagne

A Helping Hand to Overcome Solubility Challenges in Chemical Protein Synthesis

scientific article published on 17 August 2016

A mechanically interlocked molecular system programmed for the delivery of an anticancer drug

scientific article published on 25 February 2015

A straightforward method for automated Fmoc-based synthesis of bio-inspired peptide crypto-thioesters.

scientific article

A synthetic kisspeptin analog that triggers ovulation and advances puberty

scientific article published on June 2016

A water soluble Cu(I)-NHC for CuAAC ligation of unprotected peptides under open air conditions

scientific article published on 16 March 2012

Activation of TRPV2 and BKCa channels by the LL-37 enantiomers stimulates calcium entry and migration of cancer cells

scientific article published on 16 March 2016

Acute and subacute effects of a synthetic kisspeptin analog, C6, on serum concentrations of luteinizing hormone, follicle stimulating hormone, and testosterone in prepubertal bull calves

scientific article published on 06 March 2019

Alkyne-Azide Click Chemistry Mediated Carbanucleosides Synthesis

article

An optimized protocol for the synthesis of N-2-hydroxybenzyl-cysteine peptide crypto-thioesters

scientific article published on 09 October 2020

Catalytic "active-metal" template synthesis of [2]rotaxanes, [3]rotaxanes, and molecular shuttles, and some observations on the mechanism of the cu(i)-catalyzed azide-alkyne 1,3-cycloaddition.

scientific article

Catalytic "click" rotaxanes: a substoichiometric metal-template pathway to mechanically interlocked architectures

scientific article published in February 2006

Chemoselective Formation of Successive Triazole Linkages in One Pot: “Click−Click” Chemistry

scientific article published on 01 September 2006

Combining triazole ligation and enzymatic glycosylation on solid phase simplifies the synthesis of very long glycoprotein analogues

scientific article published on 14 April 2015

Complete 1H, 15N and 13C assignment of trappin-2 and 1H assignment of its two domains, elafin and cementoin

scientific article

Efficient synthesis of cysteine-rich cyclic peptides through intramolecular native chemical ligation of N-Hnb-Cys peptide crypto-thioesters

scientific article published on 2 December 2016

Imaging of extracellular cathepsin S activity by a selective near infrared fluorescence substrate-based probe

scientific article published on 23 March 2019

In Silico Peptide Ligation: Iterative Residue Docking and Linking as a New Approach to Predict Protein-Peptide Interactions

scientific article published on 05 April 2019

Initial Insights into Structure-Activity Relationships of Avian Defensins

scientific article

Native Chemical Ligation Strategy to Overcome Side Reactions during Fmoc-Based Synthesis of C-Terminal Cysteine-Containing Peptides

scientific article published on 16 February 2016

Primary structure and antibacterial activity of chicken bone marrow-derived beta-defensins

scientific article published on 8 September 2009

Rational design of triazololipopeptides analogs of kisspeptin inducing a long-lasting increase of gonadotropins

scientific article

Rotaxane-Based Propeptides: Protection and Enzymatic Release of a Bioactive Pentapeptide

scientific article published on 01 January 2009

Rotaxanes of cyclic peptides

scientific article published in February 2006

Second generation specific-enzyme-activated rotaxane propeptides

scientific article

Solid phase oxime ligations for the iterative synthesis of polypeptide conjugates

scientific article published in August 2014

Spermaurin, an La1-like peptide from the venom of the scorpion Scorpio maurus palmatus, improves sperm motility and fertilization in different mammalian species.

scientific article

Structure, function, and evolution of Gga-AvBD11, the archetype of the structural avian-double-β-defensin family

scientific article published on 23 December 2019

Study of Different Copper (I) Catalysts for the “Click Chemistry” Approach to Carbanucleosides

scientific article published on 01 January 2007

Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S.

scientific article published on 7 December 2017

Sulfenic acids in the carbohydrate field. Synthesis of transient glycosulfenic acids and their addition to unsaturated acceptors

scientific article published in October 2002

Sulfur-containing amide-based [2]rotaxanes and molecular shuttles

Synthesis and antiviral activity of novel acyclic nucleosides in the 5-alkynyl- and 6-alkylfuro[2,3-d]pyrimidine series.

scientific article published on February 2005

Synthesis of 5-haloethynyl- and 5-(1,2-dihalo)vinyluracil nucleosides: antiviral activity and cellular toxicity.

scientific article published on November 2005

Synthesis of a biologically active triazole-containing analogue of cystatin A through successive peptidomimetic alkyne-azide ligations.

scientific article

Synthesis of aryl-thioglycopeptides through chemoselective Pd-mediated conjugation

scientific article published on 20 September 2018

The Ancestral N-Terminal Domain of Big Defensins Drives Bacterially Triggered Assembly into Antimicrobial Nanonets

scientific article published on 22 October 2019

The kisspeptin analog C6 is a possible alternative to PMSG (pregnant mare serum gonadotropin) for triggering synchronized and fertile ovulations in the Alpine goat

scientific article published on 28 March 2019

The nuclear magnetic resonance solution structure of the synthetic AhPDF1.1b plant defensin evidences the structural feature within the γ-motif

scientific article

Towards the simplification of protein synthesis: iterative solid-supported ligations with concomitant purifications

scientific article published on 10 October 2012

List of works by Vincent Aucagne

A Helping Hand to Overcome Solubility Challenges in Chemical Protein Synthesis

A mechanically interlocked molecular system programmed for the delivery of an anticancer drug

A straightforward method for automated Fmoc-based synthesis of bio-inspired peptide crypto-thioesters.

A synthetic kisspeptin analog that triggers ovulation and advances puberty

A water soluble Cu(I)-NHC for CuAAC ligation of unprotected peptides under open air conditions

Activation of TRPV2 and BKCa channels by the LL-37 enantiomers stimulates calcium entry and migration of cancer cells

Acute and subacute effects of a synthetic kisspeptin analog, C6, on serum concentrations of luteinizing hormone, follicle stimulating hormone, and testosterone in prepubertal bull calves

Alkyne-Azide Click Chemistry Mediated Carbanucleosides Synthesis

An optimized protocol for the synthesis of N-2-hydroxybenzyl-cysteine peptide crypto-thioesters

Catalytic "active-metal" template synthesis of [2]rotaxanes, [3]rotaxanes, and molecular shuttles, and some observations on the mechanism of the cu(i)-catalyzed azide-alkyne 1,3-cycloaddition.

Catalytic "click" rotaxanes: a substoichiometric metal-template pathway to mechanically interlocked architectures

Chemoselective Formation of Successive Triazole Linkages in One Pot: “Click−Click” Chemistry

Combining triazole ligation and enzymatic glycosylation on solid phase simplifies the synthesis of very long glycoprotein analogues

Complete 1H, 15N and 13C assignment of trappin-2 and 1H assignment of its two domains, elafin and cementoin

Efficient synthesis of cysteine-rich cyclic peptides through intramolecular native chemical ligation of N-Hnb-Cys peptide crypto-thioesters

Imaging of extracellular cathepsin S activity by a selective near infrared fluorescence substrate-based probe

In Silico Peptide Ligation: Iterative Residue Docking and Linking as a New Approach to Predict Protein-Peptide Interactions

Initial Insights into Structure-Activity Relationships of Avian Defensins

Native Chemical Ligation Strategy to Overcome Side Reactions during Fmoc-Based Synthesis of C-Terminal Cysteine-Containing Peptides

Primary structure and antibacterial activity of chicken bone marrow-derived beta-defensins

Rational design of triazololipopeptides analogs of kisspeptin inducing a long-lasting increase of gonadotropins

Rotaxane-Based Propeptides: Protection and Enzymatic Release of a Bioactive Pentapeptide

Rotaxanes of cyclic peptides

Second generation specific-enzyme-activated rotaxane propeptides

Solid phase oxime ligations for the iterative synthesis of polypeptide conjugates

Spermaurin, an La1-like peptide from the venom of the scorpion Scorpio maurus palmatus, improves sperm motility and fertilization in different mammalian species.

Structure, function, and evolution of Gga-AvBD11, the archetype of the structural avian-double-β-defensin family

Study of Different Copper (I) Catalysts for the “Click Chemistry” Approach to Carbanucleosides

Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S.

Sulfenic acids in the carbohydrate field. Synthesis of transient glycosulfenic acids and their addition to unsaturated acceptors

Sulfur-containing amide-based [2]rotaxanes and molecular shuttles

Synthesis and antiviral activity of novel acyclic nucleosides in the 5-alkynyl- and 6-alkylfuro[2,3-d]pyrimidine series.

Synthesis of 5-haloethynyl- and 5-(1,2-dihalo)vinyluracil nucleosides: antiviral activity and cellular toxicity.

Synthesis of a biologically active triazole-containing analogue of cystatin A through successive peptidomimetic alkyne-azide ligations.

Synthesis of aryl-thioglycopeptides through chemoselective Pd-mediated conjugation

The Ancestral N-Terminal Domain of Big Defensins Drives Bacterially Triggered Assembly into Antimicrobial Nanonets

The kisspeptin analog C6 is a possible alternative to PMSG (pregnant mare serum gonadotropin) for triggering synchronized and fertile ovulations in the Alpine goat

The nuclear magnetic resonance solution structure of the synthetic AhPDF1.1b plant defensin evidences the structural feature within the γ-motif

Towards the simplification of protein synthesis: iterative solid-supported ligations with concomitant purifications