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List of works by Borna Relja

A nationwide fluidics biobank of polytraumatized patients: implemented by the Network "Trauma Research" (NTF) as an expansion to the TraumaRegister DGU® of the German Trauma Society (DGU)

scientific article published on 19 July 2019

A peptide inhibitor of C-jun N-terminal kinase modulates hepatic damage and the inflammatory response after hemorrhagic shock and resuscitation

scientific article published in August 2008

Activated thrombin-activatable fibrinolysis inhibitor (TAFIa) levels are decreased in patients with trauma-induced coagulopathy.

scientific article

Acute Alcohol Binge Deteriorates Metabolic and Respiratory Compensation Capability After Blunt Chest Trauma Followed by Hemorrhagic Shock-A New Research Model.

scientific article published on 17 July 2017

Acute alcohol intoxication reduces mortality, inflammatory responses and hepatic injury after haemorrhage and resuscitation in vivo.

scientific article

Acute ethanol administration results in a protective cytokine and neuroinflammatory profile in traumatic brain injury

scientific article

Acute ethanol gavage attenuates hemorrhage/resuscitation-induced hepatic oxidative stress in rats.

scientific article published on 5 April 2012

Adrenergic stimulation alters the expression of inflammasome components and interleukins in primary human monocytes

scientific article published on 10 November 2015

Alcohol Binge Reduces Systemic Leukocyte Activation and Pulmonary PMN Infiltration After Blunt Chest Trauma and Hemorrhagic Shock

scientific article published on 01 April 2019

Alcohol Intoxication Reduces Systemic Interleukin-6 Levels and Leukocyte Counts After Severe TBI Compared With Not Intoxicated TBI Patients

scientific article published on 28 March 2016

Alcohol‑induced attenuation of post‑traumatic inflammation is not necessarily liver‑protective following trauma/hemorrhage

scientific article published on 27 June 2019

Altered expression of beta1 integrins in renal carcinoma cell lines exposed to the differentiation inducer valproic acid.

scientific article published on August 2006

CXCR4 chemokine receptor engagement modifies integrin dependent adhesion of renal carcinoma cells

scientific article published on 10 July 2007

Cardiac Glucose and Fatty Acid Transport After Experimental Mono- and Polytrauma

scientific article published on 15 July 2019

Cell-based therapy by implanted human bone marrow-derived mononuclear cells improved bone healing of large bone defects in rats.

scientific article published on 13 April 2015

Characterization of blunt chest trauma in a long-term porcine model of severe multiple trauma.

scientific article published on 21 December 2016

Circulating Extracellular Vesicles and Their miR "Barcode" Differentiate Alcohol Drinkers With Liver Injury and Those Without Liver Injury in Severe Trauma Patients

scientific article published on 25 February 2019

Circulating leukotriene B4 identifies respiratory complications after trauma.

scientific article published on 7 March 2012

Club cell protein 16 in sera from trauma patients modulates neutrophil migration and functionality via CXCR1 and CXCR2

scientific article published on 30 October 2019

Comparative Analysis of the Regulatory T Cells Dynamics in Peripheral Blood in Human and Porcine Polytrauma.

scientific article published on 13 March 2018

Contributing factors in the development of acute lung injury in a murine double hit model

scientific article published on 01 April 2019

Correction: Renal cell carcinoma alters endothelial receptor expression responsible for leukocyte adhesion

scientific article published on January 2017

Cytokines in Inflammatory Disease

scientific article published on 28 November 2019

Damage-associated molecular patterns in trauma

scientific article published on 14 October 2019

Danger signals in trauma.

scientific article published on 4 May 2018

Decreased inflammatory responses of human lung epithelial cells after ethanol exposure are mimicked by ethyl pyruvate

scientific article published on 3 November 2014

Differential Relevance of NF-κB and JNK in the Pathophysiology of Hemorrhage/Resususcitation-Induced Liver Injury after Chronic Ethanol Feeding

scientific article

Differential effects of GdCl3- or MDP treatment on rat liver microcirculation and gene expression in the hepatic non-parenchymal cell fraction in LPS shock

scientific article

Early Local Inhibition of Club Cell Protein 16 Following Chest Trauma Reduces Late Sepsis-Induced Acute Lung Injury

scientific article published on 22 June 2019

Early decreased TLR2 expression on monocytes is associated with their reduced phagocytic activity and impaired maturation in a porcine polytrauma model

scientific article published on 10 November 2017

Effect of suppressor of cytokine signaling on hepcidin production in hepatitis C virus replicon cells.

scientific article published on 23 February 2011

Effects of acute ethanol gavage on intestinal integrity after hemorrhage/resuscitation

scientific article published in April 2013

Effects of green tea catechins on the pro-inflammatory response after haemorrhage/resuscitation in rats

scientific article published on 4 February 2011

Effects of positive blood alcohol concentration on outcome and systemic interleukin-6 in major trauma patients.

scientific article published on 28 January 2016

Endogenous Uteroglobin as Intrinsic Anti-inflammatory Signal Modulates Monocyte and Macrophage Subsets Distribution Upon Sepsis Induced Lung Injury

scientific article published on 01 October 2019

Enhanced Susceptibility of ADAP-Deficient Mice to <i>Listeria monocytogenes</i> Infection Is Associated With an Altered Phagocyte Phenotype and Function

scientific article published on 30 September 2021

Enhanced pro-inflammatory response and higher mortality rates in geriatric trauma patients

scientific article published on 24 December 2019

Establishment and characterization of the Masquelet induced membrane technique in a rat femur critical-sized defect model

scientific article published on 8 November 2013

Ethanol Decreases Inflammatory Response in Human Lung Epithelial Cells by Inhibiting the Canonical NF-kB-Pathway

scientific article published on 24 August 2017

Ethanol, ethyl and sodium pyruvate decrease the inflammatory responses of human lung epithelial cells via Akt and NF-κB in vitro but have a low impact on hepatocellular cells

scientific article published on 11 December 2015

Ethyl pyruvate ameliorates hepatic injury following blunt chest trauma and hemorrhagic shock by reducing local inflammation, NF-kappaB activation and HMGB1 release.

scientific article published on 8 February 2018

Ethyl pyruvate reduces acute lung damage following trauma and hemorrhagic shock via inhibition of NF-κB and HMGB1.

scientific article published on 16 October 2017

Evidence for early presence of intestinal epithelial cell damage in multitrauma patients.

scientific article published on 13 March 2008

Hepatic Osteodystrophy-Molecular Mechanisms Proposed to Favor Its Development.

scientific article published on 24 May 2019

I-FABP and L-FABP are early markers for abdominal injury with limited prognostic value for secondary organ failures in the post-traumatic course

scientific article published on April 2015

I-FABP is a Novel Marker for the Detection of Intestinal Injury in Severely Injured Trauma Patients.

scientific article published on 18 July 2017

Impaired Surface Expression of HLA-DR, TLR2, TLR4, and TLR9 in Ex Vivo-In Vitro Stimulated Monocytes from Severely Injured Trauma Patients

scientific article

Influence of gender on systemic IL-6 levels, complication rates and outcome after major trauma

scientific article

Inhibition of c-Jun N-terminal kinase after hemorrhage but before resuscitation mitigates hepatic damage and inflammatory response in male rats

scientific article

Innate Immunity and Alcohol

scientific article published on 14 November 2019

Intestinal-FABP and liver-FABP: Novel markers for severe abdominal injury

scientific article published on 01 July 2010

Leukotriene B4 indicates lung injury and on-going inflammatory changes after severe trauma in a porcine long-term model

scientific article published on 22 September 2017

Long-Term Effects of Induced Hypothermia on Local and Systemic Inflammation - Results from a Porcine Long-Term Trauma Model

scientific article published on 4 May 2016

M1 But Not M0 Extracellular Vesicles Induce Polarization of RAW264.7 Macrophages Via the TLR4-NFκB Pathway In Vitro

scientific article published on 22 April 2020

Midkine Is Elevated After Multiple Trauma and Acts Directly on Human Cardiomyocytes by Altering Their Functionality and Metabolism

scientific article published on 21 August 2019

Modeling trauma in rats: similarities to humans and potential pitfalls to consider

scientific article published on 05 September 2019

Modulation of inflammation by alcohol exposure

scientific article published on 5 February 2014

Modulation of the CXC-chemokine expression profile on tumor cells by the immunosuppressive drug mycophenolate mofetil.

scientific article

Monotrauma is associated with enhanced remote inflammatory response and organ damage, while polytrauma intensifies both in porcine trauma model

scientific article published on 12 March 2019

Mycophenolate mofetil modulates adhesion receptors of the beta1 integrin family on tumor cells: impact on tumor recurrence and malignancy

scientific article

Myeloid knockout of HIF-1 α does not markedly affect hemorrhage/resuscitation-induced inflammation and hepatic injury.

scientific article published in June 2014

Nlrp1 inflammasome is downregulated in trauma patients.

scientific article published on 2 August 2015

Phagocytizing activity of PMN from severe trauma patients in different post-traumatic phases during the 10-days post-injury course.

scientific article published on 29 September 2016

Plant polyphenols attenuate hepatic injury after hemorrhage/resuscitation by inhibition of apoptosis, oxidative stress, and inflammation via NF-kappaB in rats

scientific article published on 23 June 2011

Pre- or post-treatment with ethanol and ethyl pyruvate results in distinct anti-inflammatory responses of human lung epithelial cells triggered by interleukin-6.

scientific article published on 8 May 2015

Prostate tumor CXC-chemokine profile correlates with cell adhesion to endothelium and extracellular matrix

scientific article published on 02 November 2005

Rapid development of intestinal cell damage following severe trauma: a prospective observational cohort study.

scientific article published on 08 June 2009

Reduced NLRP3 Gene Expression Limits the IL-1β Cleavage via Inflammasome in Monocytes from Severely Injured Trauma Patients.

scientific article published on 9 May 2018

Renal cell carcinoma alters endothelial receptor expression responsible for leukocyte adhesion.

scientific article published on March 2016

Role of biomarkers in acute traumatic lung injury

scientific article published on 24 August 2017

STAT6 mediates the effect of ethanol on neuroinflammatory response in TBI

scientific article published on 15 June 2019

Sera from severe trauma patients with pneumonia and without infectious complications have differential effects on neutrophil biology

scientific article

Serum α-1 Antitrypsin (AAT) antagonizes intrinsic apoptosis induction in neutrophils from patients with systemic inflammatory response syndrome

scientific article

Severe Hemorrhagic Shock Leads to a Delayed Fracture Healing and Decreased Bone Callus Strength in a Mouse Model

scientific article published on 9 August 2017

Significant decline of peripheral myeloid dendritic cells following multiple trauma

scientific article

Simvastatin Reduces Cancerogenic Potential of Renal Cancer Cells via Geranylgeranyl Pyrophosphate and Mevalonate Pathway

scientific article published on 4 April 2016

Simvastatin exerts anticancer effects in osteosarcoma cell lines via geranylgeranylation and c-Jun activation.

scientific article published on 28 February 2018

Simvastatin inhibits cell growth and induces apoptosis and G0/G1 cell cycle arrest in hepatic cancer cells

scientific article published on November 2010

Simvastatin modulates the adhesion and growth of hepatocellular carcinoma cells via decrease of integrin expression and ROCK

scientific article published on 28 December 2010

Simvastatin reduces mortality and hepatic injury after hemorrhage/resuscitation in rats

scientific article published in July 2010

Smoking Dependent Alterations in Bone Formation and Inflammation Represent Major Risk Factors for Complications Following Total Joint Arthroplasty

scientific article published on 24 March 2019

Suppression of the interleukin-1ß-induced inflammatory response of human Chang liver cells by acute and subacute exposure to alcohol: an in vitro study.

scientific article published in April 2018

The effect of brain injury on the inflammatory response following severe trauma

scientific article published on 27 November 2015

The influence of alcohol on the outcome of trauma patients: a matched-pair analysis of the TraumaRegister DGU®

scientific article published on 25 September 2019

The posttraumatic activation of CD4+ T regulatory cells is modulated by TNFR2- and TLR4-dependent pathways, but not by IL-10

scientific article published on 22 June 2018

Thrombin-activatable fibrinolysis inhibitor (TAFI) is enhanced in major trauma patients without infectious complications

scientific article published on 09 June 2012

Transient down-regulation of beta1 integrin subtypes on kidney carcinoma cells is induced by mechanical contact with endothelial cell membranes

scientific article published on July 2007

Traumatic Injury

scientific article published on 01 January 2018

Traumatic injury pattern is of equal relevance as injury severity for experimental (poly)trauma modeling

scientific article published on 05 April 2019

Treatment of endothelial cell with flavonoids modulates transendothelial leukocyte migration.

scientific article published on 2 May 2014

Valproic acid inhibits adhesion of vincristine- and cisplatin-resistant neuroblastoma tumour cells to endothelium

scientific article published on 15 May 2007

Valproic acid modulates NCAM polysialylation and polysialyltransferase mRNA expression in human tumor cells.

scientific article

[Pathophysiology of multiple trauma : intensive care medicine and timing of treatment]

scientific article published on 01 September 2013

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