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List of works by Ricardo Pérez-Tomás

A microscopic study of the tracheal epithelium of Testudo graeca and Pseudemys scripta elegans.

scientific article

AT514, a cyclic depsipeptide from Serratia marcescens, induces apoptosis of B-chronic lymphocytic leukemia cells: interference with the Akt/NF-kappaB survival pathway.

scientific article published in April 2005

Activation of protein kinase C for protection of cells against apoptosis induced by the immunosuppressor prodigiosin

scientific article published in February 2002

Anion transporters and biological systems

scientific article published on 3 April 2013

Antiproliferative properties of iron supramolecular cylinders

Bcl-2 family proteins and cytoskeleton changes involved in DM-1 cytotoxic effect on melanoma cells

scientific article published on 23 January 2013

Cell cycle arrest and proapoptotic effects of the anticancer cyclodepsipeptide serratamolide (AT514) are independent of p53 status in breast cancer cells

scientific article published on 18 November 2005

Chloride, carboxylate and carbonate transport by ortho-phenylenediamine-based bisureas

article

Click-tambjamines as efficient and tunable bioactive anion transporters

scientific article published on 01 March 2020

DNA interaction and dual topoisomerase I and II inhibition properties of the anti-tumor drug prodigiosin

scientific article

Distribution of mucins in the mucosa of the digestive tract of reptiles: a histochemical study

scientific article published on 01 January 1989

EPIDERMAL GROWTH FACTOR RECEPTOR (EGF-R) LOCALIZATION IN THE APICAL MEMBRANE OF THE ENTEROCYTES OF RAT DUODENUM

scientific article published in July 1999

Editorial [Hot topic: Molecular Mechanisms of Cancer Cell Death (Executive Editor: Ricardo Perez-Tomas)]

scientific article published in January 2010

Effects of the proapoptotic drug prodigiosin on cell cycle-related proteins in Jurkat T cells

scientific article published in April 2003

Eye regeneration assay reveals an invariant functional left-right asymmetry in the early bilaterian, Dugesia japonica

scientific article published in May 2005

Facilitated Anion Transport Induces Hyperpolarization of the Cell Membrane That Triggers Differentiation and Cell Death in Cancer Stem Cells

scientific article published on 3 December 2015

Fluorescent transmembrane anion transporters: shedding light on anionophoric activity in cells

scientific article published on 26 April 2016

From Proteomic Analysis to Potential Therapeutic Targets: Functional Profile of Two Lung Cancer Cell Lines, A549 and SW900, Widely Studied in Pre-Clinical Research

scientific article

Full elucidation of the transmembrane anion transport mechanism of squaramides using in silico investigations

scientific article published on 01 August 2018

High cytotoxic sensitivity of the human small cell lung doxorubicin-resistant carcinoma (GLC4/ADR) cell line to prodigiosin through apoptosis activation

scientific article published in April 2005

Highly Cytotoxic Ruthenium(II)-Arene Complexes from Bulky 1-Pyrenylphosphane Ligands

scientific article published on 16 November 2018

Histochemical and ultrastructural study of the digestive tract of the tortoise Testudo graeca (Testudines)

scientific article published on 01 June 1990

Identification of dual mTORC1 and mTORC2 inhibitors in melanoma cells: prodigiosin vs. obatoclax.

scientific article

Immunochemical localization of transforming growth factor-alpha-related protein in the rat kidney

scientific article published on 01 January 1999

Immunoelectron microscopic localisation of transforming growth factor alpha in rat colon

scientific article published on August 1994

Immunohistochemical identification of TGF-β1 at the maxillaries in growing Sprague–Dawley rats and after muscle section

scientific article published in April 2008

Immunohistochemical localization of transforming growth factor-? and epidermal growth factor-receptor in the mesonephros and metanephros of the chicken

scientific article published in January 1993

Immunohistochemical localization of transforming growth factor-α in choroid plexus of the rat and chicken

scientific article published in December 1993

Immunolocalization of transforming growth factor-alpha and epidermal growth factor receptor in the rat gastroduodenal area

scientific article published on 01 July 1999

Indole-based perenosins as highly potent HCl transporters and potential anti-cancer agents

scientific article published on 24 August 2017

Inhibition of Human Enhancer of Zeste Homolog 2 with Tambjamine Analogs.

scientific article published in August 2017

Lactate in the Tumor Microenvironment: An Essential Molecule in Cancer Progression and Treatment

scientific article published on 03 November 2020

Mechanisms of prodigiosin cytotoxicity in human neuroblastoma cell lines

scientific article published on 4 July 2007

Mitochondria-mediated apoptosis operating irrespective of multidrug resistance in breast cancer cells by the anticancer agent prodigiosin

scientific article published in October 2004

Molecular interactions of prodiginines with the BH3 domain of anti-apoptotic Bcl-2 family members

scientific article

Multidrug resistance protein 1 localization in lipid raft domains and prostasomes in prostate cancer cell lines

scientific article published on 5 December 2014

Multidrug resistance: retrospect and prospects in anti-cancer drug treatment.

scientific article published on January 2006

N-Triethylene glycol (N-TEG) as a surrogate for the N-methyl group: application to Sansalvamide A peptide analogs

scientific article published on July 2013

New insights on the antitumoral properties of prodiginines.

scientific article

Non-Switching 1,2-Dithienylethene-based Diplatinum(II) Complex Showing High Cytotoxicity

scientific article

Non-apoptotic concentrations of prodigiosin (H+/Cl- symporter) inhibit the acidification of lysosomes and induce cell cycle blockage in colon cancer cells

scientific article published on 29 August 2005

Nonprotonophoric Electrogenic Cl − Transport Mediated by Valinomycin-like Carriers

scientific article published in July 2016

Novel Indole-based Tambjamine-Analogues Induce Apoptotic Lung Cancer Cell Death through p38 Mitogen-Activated Protein Kinase Activation

scientific article published on 10 April 2017

Overcoming drug resistance by enhancing apoptosis of tumor cells.

scientific article published on May 2009

Peptide dendrimers based on polyproline helices

scientific article

Photoactivation of the Cytotoxic Properties of Platinum(II) Complexes through Ligand Photoswitching

scientific article published on 15 March 2018

Photoswitching the cytotoxic properties of platinum(II) compounds

scientific article

Prodigiosin from the supernatant of Serratia marcescens induces apoptosis in haematopoietic cancer cell lines

scientific article published in October 2000

Prodigiosin induces apoptosis by acting on mitochondria in human lung cancer cells

scientific article published in December 2003

Prodigiosin induces apoptosis of B and T cells from B-cell chronic lymphocytic leukemia.

scientific article published in April 2003

Prodigiosin induces the proapoptotic gene NAG-1 via glycogen synthase kinase-3beta activity in human breast cancer cells

scientific article published on January 2007

Prodigiosin-induced apoptosis in human colon cancer cells

scientific article published in March 2001

Proteomic analysis of prodigiosin-induced apoptosis in a breast cancer mitoxantrone-resistant (MCF-7 MR) cell line

scientific article published in February 2007

Small molecule anionophores promote transmembrane anion permeation matching CFTR activity

scientific article published on 8 February 2018

Structure-activity relationships in tripodal transmembrane anion transporters: the effect of fluorination

scientific article

Synthesis and biological evaluation of a post-synthetically modified Trp-based diketopiperazine

Synthesis and g-quadruplex-binding properties of defined acridine oligomers.

scientific article published on 13 June 2010

Synthetic tambjamine analogues induce mitochondrial swelling and lysosomal dysfunction leading to autophagy blockade and necrotic cell death in lung cancer

scientific article published on 24 November 2016

Tambjamine alkaloids and related synthetic analogs: efficient transmembrane anion transporters.

scientific article

Targeting Autophagy for Cancer Treatment and Tumor Chemosensitization

scientific article published on 19 October 2019

The anticancer agent prodigiosin induces p21WAF1/CIP1 expression via transforming growth factor-beta receptor pathway

scientific article published on 18 July 2007

The curcumin analog DM-1 induces apoptotic cell death in melanoma

scientific article

The cytotoxic prodigiosin induces phosphorylation of p38-MAPK but not of SAPK/JNK.

scientific article published in March 2002

The effect of potential supramolecular-bond promoters on the DNA-interacting abilities of copper-terpyridine compounds

scientific article published on 19 August 2015

The prodigiosins, proapoptotic drugs with anticancer properties

scientific article published on October 2003

The prodigiosins: a new family of anticancer drugs

scientific article

Towards “drug-like” indole-based transmembrane anion transporters

article published in 2012

Transforming growth factor-alpha precursors in human colon carcinoma cells

scientific article published in 2001

Transmembrane anion transport and cytotoxicity of synthetic tambjamine analogs

scientific article published on March 2014

Understanding autophagy in cell death control.

scientific article published on January 2010

pH-Driven preparation of two related platinum(ii) complexes exhibiting distinct cytotoxic properties

scientific article