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List of works by Alex Thompson

A New Transgenic Mouse Model for the Study of Cell Cycle Control in Megakaryocytes

article

AINT/ERIC/TACC: an expanding family of proteins with C-terminal coiled coil domains.

scientific article

Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells

scientific article published on 8 December 2005

Characterization and localization of expression of an erythropoietin-induced gene, ERIC-1/TACC3, identified in erythroid precursor cells

scientific article

Complete array of HOX gene expression by RQ-PCR.

scientific article published in January 2009

Continuous MLL-ENL expression is necessary to establish a "Hox Code" and maintain immortalization of hematopoietic progenitor cells

scientific article published on October 2005

Correlation of TACC3, FGFR3, MMSET and p21 expression with the t(4;14)(p16.3;q32) in multiple myeloma

scientific article published in July 2004

Decitabine-Vorinostat combination treatment in acute myeloid leukemia activates pathways with potential for novel triple therapy

scientific article published on 19 May 2017

Deregulated expression of c-myc in megakaryocytes of transgenic mice increases megakaryopoiesis and decreases polyploidization

scientific article published in September 1996

Differential Hox expression in murine embryonic stem cell models of normal and malignant hematopoiesis.

scientific article published on 5 January 2011

Effects of nitric oxide inhibition on systemic and renal hemodynamics in the hemorrhaged rat

scientific article published on 01 January 1996

Endothelin receptor A blockade alters hemodynamic response to nitric oxide inhibition in rats

scientific article published on 01 August 1995

Entinostat prevents leukemia maintenance in a collaborating oncogene-dependent model of cytogenetically normal acute myeloid leukemia

scientific article published in July 2013

Global down-regulation of HOX gene expression in PML-RARalpha + acute promyelocytic leukemia identified by small-array real-time PCR.

scientific article published on February 2003

Grappling with the HOX network in hematopoiesis and leukemia.

scientific article published on May 2008

HOX genes in normal, engineered and malignant hematopoiesis

scientific article published on 01 January 2018

HOXA/PBX3 knockdown impairs growth and sensitizes cytogenetically normal acute myeloid leukemia cells to chemotherapy

scientific article published on 28 March 2013

High incidence of proviral integrations in the Hoxa locus in a new model of E2a-PBX1-induced B-cell leukemia.

scientific article

HoxA cluster is haploinsufficient for activity of hematopoietic stem and progenitor cells

scientific article published on 23 July 2010

Hoxa cluster genes determine the proliferative activity of adult mouse hematopoietic stem and progenitor cells.

scientific article

Hoxa6 potentiates short-term hemopoietic cell proliferation and extended self-renewal.

scientific article

Hoxa9 collaborates with E2A-PBX1 in mouse B cell leukemia in association with Flt3 activation and decrease of B cell gene expression

scientific article

Inhibition of HOX/PBX dimer formation leads to necroptosis in acute myeloid leukemia cells

scientific article published on 7 August 2017

Integrated analysis of the molecular action of Vorinostat identifies epi-sensitised targets for combination therapy.

scientific article published on July 2017

Low-dose salinomycin induces anti-leukemic responses in AML and MLL.

scientific article published on 06 September 2016

Molecular dissection of Meis1 reveals 2 domains required for leukemia induction and a key role for Hoxa gene activation

scientific article published on 09 February 2006

Overexpression of cyclin D1 moderately increases ploidy in megakaryocytes

scientific article published on 01 January 2001

POU2F1 activity regulates HOXD10 and HOXD11 promoting a proliferative and invasive phenotype in head and neck cancer

scientific article

Prolonged molecular remission in PML-RARalpha-positive acute promyelocytic leukemia treated with minimal chemotherapy followed by maintenance including the histone deacetylase inhibitor sodium valproate

scientific article published in September 2005

Protein arginine-methyltransferase-dependent oncogenesis

scientific article

Quantification of Hox and surfactant protein-B transcription during murine lung development

scientific article published on 10 February 2009

Rational drug repurposing using sscMap analysis in a HOX-TALE model of leukemia.

scientific article published on January 2014

Repression of A TAF(II)32 isoform as part of a program of genes regulated during mpl ligand-induced megakaryocyte differentiation

scientific article published in August 1999

Signaling by the Mpl receptor involves IKK and NF-kappaB.

scientific article

Stroma-free hemoglobin increases blood pressure and GFR in the hypotensive rat: role of nitric oxide

scientific article published on 01 November 1994

Targeted deletion of the Hoxa cluster affects B lymphopoiesis through depletion of early lymphoid progenitors.

scientific article published on 5 April 2017

The histone deacetylase inhibitor Romidepsin induces as a cascade of differential gene expression and altered histone H3K9 marks in myeloid leukaemia cells

scientific article published on 28 May 2019

The pathophysiology of HOX genes and their role in cancer.

scientific article

Three-dimensional ex vivo co-culture models of the leukaemic bone marrow niche for functional drug testing

scientific article published on 26 April 2016

Thrombopoietin, flt3-ligand and c-kit-ligand modulate HOX gene expression in expanding cord blood CD133 cells

scientific article published in August 2004

Variable expression and silencing of CRISPR-Cas9 targeted transgenes identifies the AAVS1 locus as not an entirely safe harbour

scientific article published on 12 November 2019

c-Met inhibition in a HOXA9/Meis1 model of CN-AML.

scientific article published on 4 December 2013

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