List of works - Margherita Sisto

A failure of TNFAIP3 negative regulation maintains sustained NF-κB activation in Sjögren’s syndrome

scientific article published on 21 May 2011

A potential role of the GRO-α/CXCR2 system in Sjögren's syndrome: regulatory effects of pro-inflammatory cytokines

scientific article

ADAM17 at the interface between inflammation and autoimmunity

scientific article

Advances in the understanding of the Fc gamma receptors-mediated autoantibodies uptake

scientific article published on 09 May 2010

Altered IkBα expression promotes NF-kB activation in monocytes from primary Sjögren’s syndrome patients

scientific article published on 01 October 2012

An analysis of the human and mouse CXCR5 gene introns

scientific article published on September 2010

An analysis of the human chemokine CXC receptor 4 gene

article

Anti-Ro/SSA autoantibody-mediated regulation of extracellular matrix fibulins in human epithelial cells of the salivary gland

scientific article published in May 2009

Autoantibodies from Sjögren's syndrome induce activation of both the intrinsic and extrinsic apoptotic pathways in human salivary gland cell line A-253.

scientific article published on 21 June 2006

Autoantibodies from Sjögren's syndrome trigger apoptosis in salivary gland cell line.

scientific article

Biological role of the N-formyl peptide receptors

scientific article (publication date: 2006)

Chemokine CXC receptor 4: an evolutionary approach.

scientific article published in January 2006

Chronic inflammation enhances NGF-β/TrkA system expression via EGFR/MEK/ERK pathway activation in Sjögren's syndrome.

scientific article published on 21 February 2014

Co-culture system of human salivary gland epithelial cells and immune cells from primary Sjögren's syndrome patients: an in vitro approach to study the effects of Rituximab on the activation of the Raf-1/ERK1/2 pathway.

scientific article published on 8 November 2014

Effects of biological drug adalimumab on tumour necrosis factor-α-converting enzyme activation

scientific article published on 01 December 2009

Emerging avenues linking inflammation, angiogenesis and Sjögren's syndrome

scientific article published on 20 January 2013

Evidence for endogenous retroviruses in human chemokine receptor gene introns: possible evolutionary inferences and biological roles

scientific article published on 22 July 2010

Evolution of a "conserved" amino acid sequence: a model study of an in silico investigation of the phylogenesis of some immune receptors.

scientific article published in January 2006

Expression of pro-inflammatory TACE-TNF-α-amphiregulin axis in Sjögren’s syndrome salivary glands

scientific article published on 02 September 2010

Fcgamma receptors mediate internalization of anti-Ro and anti-La autoantibodies from Sjögren's syndrome and apoptosis in human salivary gland cell line A-253.

scientific article published on October 2007

Fibulin-6 expression and anoikis in human salivary gland epithelial cells: implications in Sjogren's syndrome

scientific article

Formyl Peptide Receptors on Immune and Nonimmune Cells: Analysis of Sequence Conservation in FPR Genes

article

Formyl peptide receptor expression in birds

scientific article

GRO-α/CXCR2 System and ADAM17 Correlated Expression in Sjögren’s Syndrome

scientific article published on 01 June 2013

IL-6 Contributes to the TGF-β1-Mediated Epithelial to Mesenchymal Transition in Human Salivary Gland Epithelial Cells

scientific article published on 10 September 2020

Inducible nitric oxide synthase expression in Leishmania-infected dog macrophages

scientific article published on 01 October 2001

Induction of TNF-alpha-converting enzyme-ectodomain shedding by pathogenic autoantibodies

scientific article published on 23 October 2009

Infection with Leishmania infantum Inhibits actinomycin D-induced apoptosis of human monocytic cell line U-937.

scientific article

Interleukin-17 and -22 synergy linking inflammation and EMT-dependent fibrosis in Sjögren's syndrome

scientific article published on 05 June 2019

Modeling of granulocyte cytoskeletal responses following fMLP challenging.

scientific article

Modulation of the Fcgamma receptors induced by anti-Ro and anti-La autoantibodies: observations in salivary gland cells

scientific article published on 9 February 2008

Molecular identification of Mycobacterium avium subspecies paratuberculosis in an Italian patient with Hashimoto's thyroiditis and Melkersson-Rosenthal syndrome

scientific article published in January 2010

Mutation, selection and the amino acid hydropathic character: a study on receptor genes involved in immune and non-immune functions

scientific article published on March 2009

Neovascularization is prominent in the chronic inflammatory lesions of Sjögren's syndrome

Neuropilin-1 is upregulated in Sjögren’s syndrome and contributes to pathological neovascularization

scientific article published on 12 January 2012

New insights into ADAMs regulation of the GRO-α/CXCR2 system: focus on Sjögren's syndrome

scientific article

Nitric oxide production by macrophages of dogs vaccinated with killed Leishmania infantum promastigotes

scientific article published on 01 July 2001

Paget's disease of bone: new therapeutic strategies

scientific article

Polimorphonuclear cell-mediated oxidative stress: sink for reactive oxygen species and cell various type damage.

scientific article published on January 2006

Pro-inflammatory role of Anti-Ro/SSA autoantibodies through the activation of Furin–TACE–amphiregulin axis

scientific article published on 29 July 2010

Proposing a relationship between Mycobacterium avium subspecies paratuberculosis infection and Hashimoto's thyroiditis

scientific article published in October 2010

Reduced expression of the chemokine receptor CCR1 in human macrophages and U-937 cells in vitro infected with Leishmania infantum.

scientific article published on April 2004

Reduced myofilament component in primary Sjögren's syndrome salivary gland myoepithelial cells

scientific article published on 4 January 2018

Regulation of mRNA caspase-8 levels by anti-nuclear autoantibodies.

scientific article published on 24 December 2009

Rituximab-mediated Raf kinase inhibitor protein induction modulates NF-κB in Sjögren syndrome

scientific article published on 01 September 2014

Salivary gland expression level of IκBα regulatory protein in Sjögren's syndrome

scientific article

Saponins from Tribulus terrestris L. protect human keratinocytes from UVB-induced damage.

scientific article

Sjögren's syndrome autoantibodies provoke changes in gene expression profiles of inflammatory cytokines triggering a pathway involving TACE/NF-κB

article

Sjögren’s Syndrome-Related Organs Fibrosis: Hypotheses and Realities

scientific article published in 2022

Sjögren’s syndrome pathological neovascularization is regulated by VEGF-A-stimulated TACE-dependent crosstalk between VEGFR2 and NF-κB

article

Special Issue-"Diseases of the Salivary Glands"

scientific article published on 30 November 2020

Structural similarities between mRNA for the formyl peptide receptors and 18S rRNA.

scientific article published in January 2005

TGFβ1-Smad canonical and -Erk noncanonical pathways participate in interleukin-17-induced epithelial-mesenchymal transition in Sjögren's syndrome

scientific article published on 10 January 2020

TNF blocker drugs modulate human TNF-α-converting enzyme pro-domain shedding induced by autoantibodies

scientific article published on 29 December 2009

The 18S rRNA is basically composed of two tandem quasirepeats. Insights into the evolution of some innate immunity receptors.

scientific article published in January 2006

The TGF-1 Signaling Pathway as an Attractive Target in the Fibrosis Pathogenesis of Sjögren's Syndrome

scientific article published on 26 November 2018

The metalloproteinase ADAM17 and the epidermal growth factor receptor (EGFR) signaling drive the inflammatory epithelial response in Sjögren's syndrome.

scientific article

The role of the epithelial-to-mesenchymal transition (EMT) in diseases of the salivary glands

scientific article published on 23 May 2018

Tumor necrosis factor inhibitors block apoptosis of human epithelial cells of the salivary glands.

scientific article published in August 2009

Understanding the Complexity of Sjögren's Syndrome: Remarkable Progress in Elucidating NF-κB Mechanisms

scientific article published on 31 August 2020

List of works by Margherita Sisto

A failure of TNFAIP3 negative regulation maintains sustained NF-κB activation in Sjögren’s syndrome

A potential role of the GRO-α/CXCR2 system in Sjögren's syndrome: regulatory effects of pro-inflammatory cytokines

ADAM17 at the interface between inflammation and autoimmunity

Advances in the understanding of the Fc gamma receptors-mediated autoantibodies uptake

Altered IkBα expression promotes NF-kB activation in monocytes from primary Sjögren’s syndrome patients

An analysis of the human and mouse CXCR5 gene introns

An analysis of the human chemokine CXC receptor 4 gene

Anti-Ro/SSA autoantibody-mediated regulation of extracellular matrix fibulins in human epithelial cells of the salivary gland

Autoantibodies from Sjögren's syndrome induce activation of both the intrinsic and extrinsic apoptotic pathways in human salivary gland cell line A-253.

Autoantibodies from Sjögren's syndrome trigger apoptosis in salivary gland cell line.

Biological role of the N-formyl peptide receptors

Chemokine CXC receptor 4: an evolutionary approach.

Chronic inflammation enhances NGF-β/TrkA system expression via EGFR/MEK/ERK pathway activation in Sjögren's syndrome.

Co-culture system of human salivary gland epithelial cells and immune cells from primary Sjögren's syndrome patients: an in vitro approach to study the effects of Rituximab on the activation of the Raf-1/ERK1/2 pathway.

Effects of biological drug adalimumab on tumour necrosis factor-α-converting enzyme activation

Emerging avenues linking inflammation, angiogenesis and Sjögren's syndrome

Evidence for endogenous retroviruses in human chemokine receptor gene introns: possible evolutionary inferences and biological roles

Evolution of a "conserved" amino acid sequence: a model study of an in silico investigation of the phylogenesis of some immune receptors.

Expression of pro-inflammatory TACE-TNF-α-amphiregulin axis in Sjögren’s syndrome salivary glands

Fcgamma receptors mediate internalization of anti-Ro and anti-La autoantibodies from Sjögren's syndrome and apoptosis in human salivary gland cell line A-253.

Fibulin-6 expression and anoikis in human salivary gland epithelial cells: implications in Sjogren's syndrome

Formyl Peptide Receptors on Immune and Nonimmune Cells: Analysis of Sequence Conservation in FPR Genes

Formyl peptide receptor expression in birds

GRO-α/CXCR2 System and ADAM17 Correlated Expression in Sjögren’s Syndrome

IL-6 Contributes to the TGF-β1-Mediated Epithelial to Mesenchymal Transition in Human Salivary Gland Epithelial Cells

Inducible nitric oxide synthase expression in Leishmania-infected dog macrophages

Induction of TNF-alpha-converting enzyme-ectodomain shedding by pathogenic autoantibodies

Infection with Leishmania infantum Inhibits actinomycin D-induced apoptosis of human monocytic cell line U-937.

Interleukin-17 and -22 synergy linking inflammation and EMT-dependent fibrosis in Sjögren's syndrome

Modeling of granulocyte cytoskeletal responses following fMLP challenging.

Modulation of the Fcgamma receptors induced by anti-Ro and anti-La autoantibodies: observations in salivary gland cells

Molecular identification of Mycobacterium avium subspecies paratuberculosis in an Italian patient with Hashimoto's thyroiditis and Melkersson-Rosenthal syndrome

Mutation, selection and the amino acid hydropathic character: a study on receptor genes involved in immune and non-immune functions

Neovascularization is prominent in the chronic inflammatory lesions of Sjögren's syndrome

Neuropilin-1 is upregulated in Sjögren’s syndrome and contributes to pathological neovascularization

New insights into ADAMs regulation of the GRO-α/CXCR2 system: focus on Sjögren's syndrome

Nitric oxide production by macrophages of dogs vaccinated with killed Leishmania infantum promastigotes

Paget's disease of bone: new therapeutic strategies

Polimorphonuclear cell-mediated oxidative stress: sink for reactive oxygen species and cell various type damage.

Pro-inflammatory role of Anti-Ro/SSA autoantibodies through the activation of Furin–TACE–amphiregulin axis

Proposing a relationship between Mycobacterium avium subspecies paratuberculosis infection and Hashimoto's thyroiditis

Reduced expression of the chemokine receptor CCR1 in human macrophages and U-937 cells in vitro infected with Leishmania infantum.

Reduced myofilament component in primary Sjögren's syndrome salivary gland myoepithelial cells

Regulation of mRNA caspase-8 levels by anti-nuclear autoantibodies.

Rituximab-mediated Raf kinase inhibitor protein induction modulates NF-κB in Sjögren syndrome

Salivary gland expression level of IκBα regulatory protein in Sjögren's syndrome

Saponins from Tribulus terrestris L. protect human keratinocytes from UVB-induced damage.

Sjögren's syndrome autoantibodies provoke changes in gene expression profiles of inflammatory cytokines triggering a pathway involving TACE/NF-κB

Sjögren’s Syndrome-Related Organs Fibrosis: Hypotheses and Realities

Sjögren’s syndrome pathological neovascularization is regulated by VEGF-A-stimulated TACE-dependent crosstalk between VEGFR2 and NF-κB

Special Issue-"Diseases of the Salivary Glands"

Structural similarities between mRNA for the formyl peptide receptors and 18S rRNA.

TGFβ1-Smad canonical and -Erk noncanonical pathways participate in interleukin-17-induced epithelial-mesenchymal transition in Sjögren's syndrome

TNF blocker drugs modulate human TNF-α-converting enzyme pro-domain shedding induced by autoantibodies

The 18S rRNA is basically composed of two tandem quasirepeats. Insights into the evolution of some innate immunity receptors.

The TGF-1 Signaling Pathway as an Attractive Target in the Fibrosis Pathogenesis of Sjögren's Syndrome

The metalloproteinase ADAM17 and the epidermal growth factor receptor (EGFR) signaling drive the inflammatory epithelial response in Sjögren's syndrome.

The role of the epithelial-to-mesenchymal transition (EMT) in diseases of the salivary glands

Tumor necrosis factor inhibitors block apoptosis of human epithelial cells of the salivary glands.

Understanding the Complexity of Sjögren's Syndrome: Remarkable Progress in Elucidating NF-κB Mechanisms