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List of works by Simon P. Graham

A comparative study of the local cytokine response in the lungs of pigs experimentally infected with different PRRSV-1 strains: upregulation of IL-1α in highly pathogenic strain induced lesions

scientific article published on 12 February 2015

A novel strategy for the identification of antigens that are recognised by bovine MHC class I restricted cytotoxic T cells in a protozoan infection using reverse vaccinology

scientific article published on 9 February 2007

Analysis of the transcriptome of the protozoan Theileria parva using MPSS reveals that the majority of genes are transcriptionally active in the schizont stage

scientific article

Assessment of the enhancement of PLGA nanoparticle uptake by dendritic cells through the addition of natural receptor ligands and monoclonal antibody

scientific article published on 31 October 2015

Assessment of the phenotype and functionality of porcine CD8 T cell responses following vaccination with live attenuated classical swine fever virus (CSFV) and virulent CSFV challenge.

scientific article published on 21 August 2013

Bovine Herpesvirus-4-Vectored Delivery of Nipah Virus Glycoproteins Enhances T Cell Immunogenicity in Pigs

scientific article published on 02 March 2020

Bovine Pestivirus Heterogeneity and Its Potential Impact on Vaccination and Diagnosis

scientific article published on 06 October 2020

CD1- and CD1+ porcine blood dendritic cells are enriched for the orthologues of the two major mammalian conventional subsets

scientific article published on 20 January 2017

CD8 T-cell responses against the immunodominant Theileria parva peptide Tp249-59 are composed of two distinct populations specific for overlapping 11-mer and 10-mer epitopes.

scientific article published on 18 June 2016

CD8+ T-cell responses to Theileria parva are preferentially directed to a single dominant antigen: Implications for parasite strain-specific immunity

scientific article

Cellular and Humoral Immune Responses after Immunisation with Low Virulent African Swine Fever Virus in the Large White Inbred Babraham Line and Outbred Domestic Pigs

scientific article published on 08 July 2022

Challenge of pigs with classical swine fever viruses after C-strain vaccination reveals remarkably rapid protection and insights into early immunity

scientific article

Challenges in Veterinary Vaccine Development and Immunization

scientific article published on January 2016

Characterisation of experimental infections of domestic pigs with genotype 2.1 and 3.3 isolates of classical swine fever virus.

scientific article

Characterisation of vaccine-induced, broadly cross-reactive IFN-γ secreting T cell responses that correlate with rapid protection against classical swine fever virus

scientific article

Characterisation of virus-specific peripheral blood cell cytokine responses following vaccination or infection with classical swine fever viruses

scientific article published on 30 September 2009

Characterization of efferent lymph cells and their function following immunization of cattle with an allogenic Theileria annulata infected cell line.

scientific article published on May 2003

Characterization of the Myeloid Cell Populations' Resident in the Porcine Palatine Tonsil

Characterization of the fine specificity of bovine CD8 T-cell responses to defined antigens from the protozoan parasite Theileria parva

scientific article

Characterization of the interaction of African swine fever virus with monocytes and derived macrophage subsets

scientific article

Comparative analysis of cytokine transcript profiles within mediastinal lymph node compartments of pigs after infection with porcine reproductive and respiratory syndrome genotype 1 strains differing in pathogenicity

scientific article

Comparative analysis of immune responses following experimental infection of pigs with European porcine reproductive and respiratory syndrome virus strains of differing virulence

scientific article published on 19 September 2012

Comparative phenotypic and functional analyses of the effects of autologous plasma and recombinant human macrophage-colony stimulating factor (M-CSF) on porcine monocyte to macrophage differentiation

scientific article published on 14 April 2017

Comparison of Macrophage Responses to African Swine Fever Viruses Reveals that the NH/P68 Strain is Associated with Enhanced Sensitivity to Type I IFN and Cytokine Responses from Classically Activated Macrophages

scientific article published on 12 March 2020

Comparison of the Immunogenicities and Cross-Lineage Efficacies of Live Attenuated Peste des Petits Ruminants Virus Vaccines PPRV/Nigeria/75/1 and PPRV/Sungri/96

scientific article published on 27 November 2018

Cytokines and the protective host immune response to Chlamydia psittaci ⬇️

scientific article published on January 1, 1998

Design and evaluation of the immunogenicity and efficacy of a biomimetic particulate formulation of viral antigens

scientific article published on 23 October 2017

Differential lung NK cell responses in avian influenza virus infected chickens correlate with pathogenicity

scientific article published on January 2013

Distinct response kinetics of gamma interferon and interleukin-4 in bovine tuberculosis.

scientific article

Down-regulated lymphoproliferation coincides with parasite maturation and with the collapse of both gamma interferon and interleukin-4 responses in a bovine model of onchocerciasis

scientific article published on July 2001

Early responses of natural killer cells in pigs experimentally infected with 2009 pandemic H1N1 influenza A virus

scientific article

Enhanced infectivity of H5N1 highly pathogenic avian influenza (HPAI) virus in pig ex vivo respiratory tract organ cultures following adaptation by in vitro passage

scientific article published on 17 September 2013

Establishing Porcine Monocyte-Derived Macrophage and Dendritic Cell Systems for Studying the Interaction with PRRSV-1.

scientific article published on 2 June 2016

Establishment of Systems to Enable Isolation of Porcine Monoclonal Antibodies Broadly Neutralizing the Porcine Reproductive and Respiratory Syndrome Virus

scientific article published on 27 March 2019

Establishment of a Bovine Viral Diarrhea Virus Type 2 Intranasal Challenge Model for Assessing Vaccine Efficacy

scientific article published on 27 February 2018

Establishment of a Pig Influenza Challenge Model for Evaluation of Monoclonal Antibody Delivery Platforms

scientific article published on 26 June 2020

Evaluation of Molecularly Imprinted Polymers as Synthetic Virus Neutralizing Antibody Mimics.

scientific article published on 24 May 2019

Evaluation of hydrophobic chitosan-based particulate formulations of porcine reproductive and respiratory syndrome virus vaccine candidate T cell antigens

scientific article published on 3 February 2017

Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19

scientific article published on 27 July 2020

Evaluation of the recognition of Theileria parva vaccine candidate antigens by cytotoxic T lymphocytes from Zebu cattle

scientific article

Extensive polymorphism and evidence of immune selection in a highly dominant antigen recognized by bovine CD8 T cells specific for Theileria annulata

scientific article

Fusion of a cell penetrating peptide from HIV-1 TAT to the Theileria parva antigen Tp2 enhances the stimulation of bovine CD8+ T cell responses

scientific article published on 26 February 2009

Head Start Immunity: Characterizing the Early Protection of C Strain Vaccine Against Subsequent Classical Swine Fever Virus Infection

scientific article published on 23 July 2019

Host-pathogen interactions during porcine reproductive and respiratory syndrome virus 1 infection of piglets

scientific article published on 02 January 2015

Immunostimulatory CpG oligodeoxynucleotides enhance the induction of bovine CD4+ cytotoxic T-lymphocyte responses against the polymorphic immunodominant molecule of the protozoan parasite Theileria parva

scientific article published on 21 November 2006

In a bovine model of onchocerciasis, protective immunity exists naturally, is absent in drug-cured hosts, and is induced by vaccination

scholarly article

Increased pathogenicity of European porcine reproductive and respiratory syndrome virus is associated with enhanced adaptive responses and viral clearance

scientific article published on 29 November 2012

Infection of monocytes with European porcine reproductive and respiratory syndrome virus (PRRSV-1) strain Lena is significantly enhanced by dexamethasone and IL-10.

scientific article published in March 2018

Interaction of porcine monocyte-derived dendritic cells with African swine fever viruses of diverse virulence.

scientific article

Is 'timing' important for cytokine polarization?

scientific article

Limited genetic and antigenic diversity within parasite isolates used in a live vaccine against Theileria parva.

scientific article

MHC Class I Bound to an Immunodominant Theileria parva Epitope Demonstrates Unconventional Presentation to T Cell Receptors

scientific article

Partial Activation of natural killer and γδ T cells by classical swine fever viruses is associated with type I interferon elicited from plasmacytoid dendritic cells.

scientific article published on 30 July 2014

Pathology and Virus Distribution in the Lung and Lymphoid Tissues of Pigs Experimentally Inoculated with Three Distinct Type 1 PRRS Virus Isolates of Varying Pathogenicity

scientific article published on 10 November 2014

Patterns of Onchocerca volvulus recombinant antigen recognition in a bovine model of onchocerciasis.

scientific article published on December 1999

Porcine Dendritic Cells and Viruses: An Update.

scientific article published on 16 May 2019

Porcine reproductive and respiratory syndrome type 1 viruses induce hypoplasia of erythroid cells and myeloid cell hyperplasia in the bone marrow of experimentally infected piglets independently of the viral load and virulence.

scientific article published on 20 January 2017

Proinflammatory cytokine expression by Theileria annulata infected cell lines correlates with the pathology they cause in vivo.

scientific article published on April 2001

Proteome-wide screening of the European porcine reproductive and respiratory syndrome virus reveals a broad range of T cell antigen reactivity

scientific article published on 17 May 2014

Proteome-wide screening reveals immunodominance in the CD8 T cell response against classical swine fever virus with antigen-specificity dependent on MHC class I haplotype expression

scientific article

Recent advances in veterinary applications of structural vaccinology

scientific article published on 15 March 2018

Recombinant ovine interferon gamma inhibits the multiplication of Chlamydia psittaci in ovine cells.

scientific article published on February 1995

The MHC homozygous inbred Babraham pig as a resource for veterinary and translational medicine

scientific article published on 23 April 2018

The Non-structural Protein 5 and Matrix Protein Are Antigenic Targets of T Cell Immunity to Genotype 1 Porcine Reproductive and Respiratory Syndrome Viruses

scientific article

The bovine CD1D gene has an unusual gene structure and is expressed but cannot present α-galactosylceramide with a C26 fatty acid

scientific article published on 11 September 2012

Theileria parva candidate vaccine antigens recognized by immune bovine cytotoxic T lymphocytes

scholarly article

Thymic depletion of lymphocytes is associated with the virulence of PRRSV-1 strains

scientific article published on 6 April 2016

Transient transfection of Theileria annulata

scientific article published on 01 April 2001

Treatment of cattle with DNA-encoded Flt3L and GM-CSF prior to immunization with Theileria parva candidate vaccine antigens induces CD4 and CD8 T cell IFN-γ responses but not CTL responses

scientific article published on 18 January 2011

Two Theileria parva CD8 T cell antigen genes are more variable in buffalo than cattle parasites, but differ in pattern of sequence diversity

scientific article

Vaccine Development for Nipah Virus Infection in Pigs

article

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