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List of works by Pascal Schneider

3-amino-1,2,4-triazole inhibits macrophage NO synthase

scientific article published on February 28, 1992

A common single nucleotide polymorphism impairs B-cell activating factor receptor's multimerization, contributing to common variable immunodeficiency.

scientific article published on 7 January 2014

A fluorescent peptide substrate for the surface metalloprotease of Leishmania.

scientific article published in March 1993

A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors.

scientific article

A mouse model of systemic lupus erythematosus responds better to soluble TACI than to soluble BAFFR, correlating with depletion of plasma cells

scientific article

A role for the src family kinase Fyn in NK cell activation and the formation of the repertoire of Ly49 receptors

scientific article published in March 2002

A secreted high-affinity inhibitor of human TNF from Tanapox virus

scholarly article

A soluble form of B cell maturation antigen, a receptor for the tumor necrosis factor family member APRIL, inhibits tumor cell growth

scientific article

APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth

scientific article

ATP release due to Thy-1–integrin binding induces P2X7-mediated calcium entry required for focal adhesion formation ⬇️

scientific article published on May 1, 2011

Aggregation of integrins and RhoA activation are required for Thy-1-induced morphological changes in astrocytes

scientific article published on 25 June 2004

Alveolar macrophages and lung dendritic cells sense RNA and drive mucosal IgA responses

scientific article

An anti-CD19 antibody coupled to a tetanus toxin peptide induces efficient Fas ligand (FasL)-mediated cytotoxicity of a transformed human B cell line by specific CD4+ T cells

scientific article published on November 1998

Analysis of the Neutral Glycan Fractions of Glycosyl-phosphatidylinositols by Thin-Layer Chromatography

article

Antibodies That Block or Activate Mouse B Cell Activating Factor of the Tumor Necrosis Factor (TNF) Family (BAFF), Respectively, Induce B Cell Depletion or B Cell Hyperplasia

scientific article published on 22 July 2016

Astrocyte-to-neuron communication through integrin-engaged Thy-1/CBP/Csk/Src complex triggers neurite retraction via the RhoA/ROCK pathway

scientific article published on 11 November 2016

Astrocytic αVβ3 integrin inhibits neurite outgrowth and promotes retraction of neuronal processes by clustering Thy-1

scientific article published in 2012

B cell activating factor is central to bleomycin- and IL-17-mediated experimental pulmonary fibrosis

scientific article published on 23 October 2014

BAFF AND APRIL: a tutorial on B cell survival

scientific article

BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population

scientific article published in July 2000

BAFF is a survival and maturation factor for mouse B cells

scientific article published on 01 July 2002

BAFF mediates survival of peripheral immature B lymphocytes

scientific article published on November 2000

BAFF production by antigen-presenting cells provides T cell co-stimulation.

scientific article published in March 2004

BAFF, APRIL and their receptors: structure, function and signaling

scientific article

BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth

scientific article

BAFF- and TACI-Dependent Processing of BAFFR by ADAM Proteases Regulates the Survival of B Cells

scientific article published in February 2017

BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF

scientific article (publication date: 14 September 2001)

Biosynthesis of the glycolipid anchor of lipophosphoglycan and the structurally related glycoinositolphospholipids from Leishmania major

scientific article published on May 1995

Buffy's, B cells, and membrane BAFF

scientific article published on 01 May 2010

C3-symmetric peptide scaffolds are functional mimetics of trimeric CD40L.

scientific article published on December 2005

Cell death-induced activation of epidermal growth factor receptor in keratinocytes: implications for restricting epidermal damage in dermatitis

scientific article published in July 2005

Characterisation of two soluble metalloexopeptidases in the protozoan parasite Leishmania major

scientific article published on 01 December 1993

Characterization and application of two RANK-specific antibodies with different biological activities

scientific article published on 7 January 2016

Characterization of Fas (Apo-1, CD95)-Fas ligand interaction

scientific article (publication date: 25 July 1997)

Characterization of GDP-alpha-D-arabinopyranose, the precursor of D-Arap in Leishmania major lipophosphoglycan

scientific article published in July 1994

Characterization of a surface metalloprotease from Herpetomonas samuelpessoai and comparison with Leishmania major promastigote surface protease

scientific article published in April 1993

Characterization of glycoinositol phospholipids in the amastigote stage of the protozoan parasite Leishmania major.

scientific article published on October 1993

Characterization of two receptors for TRAIL1 ⬇️

scientific article published on October 27, 1997

Combined loss of the BH3-only proteins Bim and Bmf restores B-cell development and function in TACI-Ig transgenic mice

scientific article

Conservation of surface molecules in the trypanosomatids

scientific article published on 01 September 1993

Conversion of Membrane-bound Fas(CD95) Ligand to Its Soluble Form Is Associated with Downregulation of Its Proapoptotic Activity and Loss of Liver Toxicity ⬇️

scientific article published on April 20, 1998

Cracking the BAFF code.

scientific article published on July 2009

Cutting edge: IL-1α is a crucial danger signal triggering acute myocardial inflammation during myocardial infarction

scientific article

Cutting edge: a novel viral TNF receptor superfamily member in virulent strains of human cytomegalovirus.

scientific article published on June 1999

Cysteine 230 is essential for the structure and activity of the cytotoxic ligand TRAIL

scientific article published on 01 July 2000

Cysteine-rich Domain 1 of CD40 Mediates Receptor Self-assembly ⬇️

scientific article published on March 5, 2013

Data for the crystal structure of APRIL-BAFF-BAFF heterotrimer.

scientific article

Dendritic Cells Cause Bone Lesions in a New Mouse Model of Histiocytosis

scientific article published on 6 August 2015

Detection of serum antibodies against Leishmania 94 kDa antigen in visceral and cutaneous leishmaniosis due to Leishmania infantum

scientific article published on 01 March 1995

Development of an Fn14 agonistic antibody as an anti-tumor agent ⬇️

scientific article published on July 1, 2011

Development of improved soluble inhibitors of FasL and CD40L based on oligomerized receptors

scientific article published on 01 April 2000

Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2.

scientific article

Differential insertion of GPI-anchored GFPs into lipid rafts of live cells.

scientific article published on 29 October 2004

Direct Thy-1/alphaVbeta3 integrin interaction mediates neuron to astrocyte communication

scientific journal article

Discordant increases in CD4+ T cells in human immunodeficiency virus-infected patients experiencing virologic treatment failure: role of changes in thymic output and T cell death

scientific article published on 8 March 2001

Distinct requirements for activation-induced cell surface expression of preformed Fas/CD95 ligand and cytolytic granule markers in T cells.

scientific article published on 12 September 2008

Ectodysplasin A (EDA) - EDA receptor signalling and its pharmacological modulation.

scientific article published on 23 January 2014

Ectodysplasin A Pathway Contributes to Human and Murine Skin Repair

scientific article published on 29 January 2016

Ectodysplasin A1 promotes placodal cell fate during early morphogenesis of ectodermal appendages

scientific article published on 15 September 2004

Ectodysplasin has a dual role in ectodermal organogenesis: inhibition of Bmp activity and induction of Shh expression

scientific article published in January 2007

Ectodysplasin regulates hormone-independent mammary ductal morphogenesis via NF-κB

scientific article published on 26 March 2012

Ectodysplasin/NF-κB Promotes Mammary Cell Fate via Wnt/β-catenin Pathway

scientific article published on 18 November 2015

Ectopic expression of the serine protease inhibitor PI9 modulates death receptor-mediated apoptosis

scientific article

Effects of fructose-containing caloric sweeteners on resting energy expenditure and energy efficiency: a review of human trials

scientific article published on 13 August 2013

Epithelial NAIPs protect against colonic tumorigenesis

scientific article

Equine herpesvirus-2 E10 gene product, but not its cellular homologue, activates NF-kappaB transcription factor and c-Jun N-terminal kinase

scientific journal article

FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activation

scientific article

FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation.

scientific article

Fas ligand elicits a caspase-independent proinflammatory response in human keratinocytes: implications for dermatitis

scientific article published on 20 July 2006

Fas ligand-induced proinflammatory transcriptional responses in reconstructed human epidermis. Recruitment of the epidermal growth factor receptor and activation of MAP kinases

scientific article published on 31 October 2007

Feather arrays are patterned by interacting signalling and cell density waves

article

Formation of virus-like clusters is an intrinsic property of the tumor necrosis factor family member BAFF (B cell activating factor).

scientific article published on February 2006

Glycoinositol-phospholipid profiles of four serotypically distinct Old World Leishmania strains

scientific article published on December 1994

Heparan sulfate proteoglycans, Fc receptors, and DC suppression

scientific article published on August 2008

Hetero-oligomerization between the TNF receptor superfamily members CD40, Fas and TRAILR2 modulate CD40 signalling

scientific article published on 09 February 2017

Human cytomegalovirus glycoprotein UL141 targets the TRAIL death receptors to thwart host innate antiviral defenses.

scientific article published on March 2013

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

scientific article

Identification of a new murine tumor necrosis factor receptor locus that contains two novel murine receptors for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)

scientific journal article

Identification of ectodysplasin target genes reveals the involvement of chemokines in hair development.

scientific article published on 26 January 2012

Identification of proteoglycans as the APRIL-specific binding partners.

scientific article

IgG subclass switch capacity is low in switched and in IgM-only, but high in IgD+IgM+, post-germinal center (CD27+) human B cells

scientific article published on 01 January 2001

Immunotherapeutic targeting of LIGHT/LTβR/HVEM pathway fully recapitulates the reduced cytotoxic phenotype of LIGHT-deficient T cells

scientific article published on 11 January 2016

Induction of the alternative NF-κB pathway by lymphotoxin αβ (LTαβ) relies on internalization of LTβ receptor

scientific article published on 6 September 2011

Inhibition of NK Reactivity Against Solid Tumors by Platelet-Derived RANKL

scientific article published on 26 February 2019

Inhibition of death receptor signals by cellular FLIP

scientific article

Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin.

scientific article

Integrin-mediated transactivation of P2X7R via hemichannel-dependent ATP release stimulates astrocyte migration.

scientific article published on 25 May 2016

Interaction of Fas(Apo‐1/CD95) with proteins implicated in the ubiquitination pathway ⬇️

scientific article (publication date: 21 July 1997)

Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human

scientific article

Intestinal bacteria condition dendritic cells to promote IgA production

scientific article

LIGHT/HVEM/LTβR Interaction as a Target for the Modulation of the Allogeneic Immune Response in Transplantation ⬇️

scientific article published on January 28, 2013

Leishmania major: differential regulation of the surface metalloprotease in amastigote and promastigote stages

scientific article published in September 1992

Leishmanolysin: surface metalloproteinase of Leishmania

scientific article published on 01 January 1995

MARCKS-related protein (MRP) is a substrate for the Leishmania major surface protease leishmanolysin (gp63).

scientific article

Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen.

scientific article

Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape

scientific article published on 01 November 1996

Membrane insertion and antibody recognition of a glycosylphosphatidylinositol-anchored protein: an optical study

scientific article published on 01 January 1993

Membrane proteins and enzymes of Leishmania

scientific article published on January 1, 1992

Modeling Edar expression reveals the hidden dynamics of tooth signaling center patterning

scientific article published on 07 February 2019

Molecular Diagnostics and In Utero Therapeutics for Orofacial Clefts

scientific article published on 01 July 2020

Molecular and Therapeutic Characterization of Anti-ectodysplasin A Receptor (EDAR) Agonist Monoclonal Antibodies ⬇️

scientific article published on July 5, 2011

Mutation of the BAFF furin cleavage site impairs B-cell homeostasis and antibody responses.

scientific article

Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans.

scientific article published on 10 July 2005

Mutations leading to X-linked hypohidrotic ectodermal dysplasia affect three major functional domains in the tumor necrosis factor family member ectodysplasin-A.

scientific article published on 14 March 2001

MyD88, an Adapter Protein Involved in Interleukin-1 Signaling ⬇️

scientific article published on May 15, 1998

N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death

scientific article published on 10 February 2017

Neonatal treatment with recombinant ectodysplasin prevents respiratory disease in dogs with X-linked ectodermal dysplasia

scientific article published in September 2009

Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with alphavbeta3 integrin that activates PKCalpha and RhoA

scientific journal article

Neutralization of (NK-cell-derived) B-cell activating factor by Belimumab restores sensitivity of chronic lymphoid leukemia cells to direct and Rituximab-induced NK lysis.

scientific article published on 24 February 2015

Neutrophil-derived APRIL concentrated in tumor lesions by proteoglycans correlates with human B-cell lymphoma aggressiveness

scientific article published on 01 January 2007

No Evidence That Soluble TACI Induces Signalling via Membrane-Expressed BAFF and APRIL in Myeloid Cells ⬇️

scientific article published on April 19, 2013

No interactions between heparin and atacicept, an antagonist of B cell survival cytokines

scientific article published on 15 October 2019

Novel strategies for expansion of tooth epithelial stem cells and ameloblast generation

scientific article published on 18 March 2020

Permanent correction of an inherited ectodermal dysplasia with recombinant EDA.

scientific article published on 7 April 2003

Pharmacological stimulation of Edar signaling in the adult enhances sebaceous gland size and function

scientific article

Primary structure of CD52.

scientific article published on March 1995

Production of recombinant TRAIL and TRAIL receptor: Fc chimeric proteins

scientific article published on 01 January 2000

Productive HIV-1 infection of primary CD4+ T cells induces mitochondrial membrane permeabilization leading to a caspase-independent cell death.

scientific article published on 31 October 2001

Progesterone/RANKL is a major regulatory axis in the human breast

scientific article published in April 2013

Programming of marginal zone B-cell fate by basic Kruppel-like factor (BKLF/KLF3)

Rationally-designed multivalent architectures for mimicking homotrimers of CD40L, a member of the TNF superfamily

scientific article published in January 2009

Receptor Activator for NF-κB Ligand in Acute Myeloid Leukemia: Expression, Function, and Modulation of NK Cell Immunosurveillance ⬇️

scientific article published on December 14, 2012

Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease-causing from risk-increasing TNFRSF13B variants in antibody deficiency syndromes

scientific article

Rescue of the mature B cell compartment in BAFF-deficient mice by treatment with recombinant Fc-BAFF.

scientific article published on 27 March 2010

Role of Glutathione in Macrophage Activation: Effect of Cellular Glutathione Depletion on Nitrite Production and Leishmanicidal Activity

article

Role of ectodysplasin signalling in middle ear and nasal pathology in rat and mouse models of hypohidrotic ectodermal dysplasia

scientific article published on 25 April 2019

Selection of peptides and synthesis of pentameric peptabody molecules reacting specifically with ErbB-2 receptor.

scientific article

Significant correction of disease after postnatal administration of recombinant ectodysplasin A in canine X-linked ectodermal dysplasia.

scientific article

Stage-specific binding of Leishmania donovani to the sand fly vector midgut is regulated by conformational changes in the abundant surface lipophosphoglycan.

scientific article

Stoichiometry of Heteromeric BAFF and APRIL Cytokines Dictates Their Receptor Binding and Signaling Properties

scientific article published on 7 May 2015

Structural studies on a lipoarabinogalactan of Crithidia fasciculata.

scientific article published on February 1996

Structure of Leishmania lipophosphoglycan: inter- and intra-specific polymorphism in Old World species

scientific article published on September 1995

Structure of the extracellular domains of human and Xenopus Fn14: implications in the evolution of TWEAK and Fn14 interactions

scientific article

Structure of the glycosyl-phosphatidylinositol membrane anchor of the Leishmania major promastigote surface protease

scientific article published in October 1990

Structure-function analysis of Eiger, the Drosophila TNF homolog.

scientific article published in March 2009

T cell costimulation by the TNF ligand BAFF.

scientific article published in December 2001

T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes

scientific article

TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts

scientific article

TNF Deficiency Fails to Protect BAFF Transgenic Mice against Autoimmunity and Reveals a Predisposition to B Cell Lymphoma

scientific article published on 01 January 2004

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

scientific article (publication date: April 2000)

TRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality.

scientific article

TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB

scientific article published in December 1997

TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95)

scientific article

TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration

scientific article

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha.

scientific article published on 7 July 2008

Targeting of Fn14 Prevents Cancer-Induced Cachexia and Prolongs Survival.

scientific article published on September 2015

The BAFF/APRIL system in SLE pathogenesis.

scientific article published on 11 March 2014

The C76R transmembrane activator and calcium modulator cyclophilin ligand interactor mutation disrupts antibody production and B-cell homeostasis in heterozygous and homozygous mice

scientific article published on 31 March 2011

The EDA-deficient mouse has Zymbal's gland hypoplasia and acute otitis externa

scientific article published in 2022

The Role of TNFR2 and DR3 in the In Vivo Expansion of Tregs in T Cell Depleting Transplantation Regimens

scientific article published on 09 May 2020

The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF

scientific article published on 01 February 2004

The biosynthesis of GDP-D-arabinopyranose in Crithidia fasciculata: characterization of a D-arabino-1-kinase activity and its use in the synthesis of GDP-[5-3H]D-arabinopyranose.

scientific article published on October 1995

The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade

scientific article

The developmental regulation and biosynthesis of GPI-related structures in Leishmania parasites.

scientific article published in February 1994

The glycoinositol-phospholipids of Phytomonas

scientific article published on October 1995

The human cytomegalovirus-encoded chemokine receptor US28 induces caspase-dependent apoptosis.

scientific article published on August 2005

The molecular architecture of the TNF superfamily

scientific article

The oncogene metadherin modulates the apoptotic pathway based on the tumor necrosis factor superfamily member TRAIL (Tumor Necrosis Factor-related Apoptosis-inducing Ligand) in breast cancer

scientific article published on 13 February 2013

The tumor necrosis factor-related apoptosis-inducing ligand receptors TRAIL-R1 and TRAIL-R2 have distinct cross-linking requirements for initiation of apoptosis and are non-redundant in JNK activation

scientific article published on 01 October 2000

Therapeutic blockade of LIGHT interaction with herpesvirus entry mediator and lymphotoxin β receptor attenuates in vivo cytotoxic allogeneic responses

scientific article published on December 2014

Therapeutic implications of NK cell regulation of allogeneic CD8 T cell-mediated immune responses stimulated through the direct pathway of antigen presentation in transplantation

article

Thy-1 binds to integrin beta(3) on astrocytes and triggers formation of focal contact sites

scientific article

Thy-1-mediated cell-cell contact induces astrocyte migration through the engagement of αVβ3 integrin and syndecan-4

scientific article

Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis ⬇️

scientific article published on October 22, 2012

Toll-like receptor agonists synergize with CD40L to induce either proliferation or plasma cell differentiation of mouse B cells

scientific article

Tools and techniques to study ligand-receptor interactions and receptor activation by TNF superfamily members

scientific article

Transduction of CpG DNA-stimulated primary human B cells with bicistronic lentivectors.

scientific article published on 11 July 2005

Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex

scientific article

Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland.

scientific article

Two mechanisms of caspase 9 processing in double-stranded RNA- and virus-triggered apoptosis.

scientific article published on January 2005

Type I interferon drives dendritic cell apoptosis via multiple BH3-only proteins following activation by PolyIC in vivo

scientific article

[44] Microscale analysis of glycosylphosphatidylinositol structures

article

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