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List of works by Tim Karl

A behavioural comparison of acute and chronic Delta9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice

scientific article published on 29 September 2009

A follow-up study: acute behavioural effects of Delta(9)-THC in female heterozygous neuregulin 1 transmembrane domain mutant mice

scientific article published on 23 June 2010

A neuregulin 1 transmembrane domain mutation causes imbalanced glutamatergic and dopaminergic receptor expression in mice

scientific article published on 27 June 2013

A transgenic mouse model of spinocerebellar ataxia type 3 resembling late disease onset and gender-specific instability of CAG repeats

scientific article published on 20 August 2009

Abca7 deletion does not affect adult neurogenesis in the mouse

scientific article published on 20 January 2016

Acoustic startle response and sensorimotor gating in a genetic mouse model for the Y1 receptor

scientific article published on 25 January 2010

Altered motor activity, exploration and anxiety in heterozygous neuregulin 1 mutant mice: implications for understanding schizophrenia.

scientific article published on 13 February 2007

Apolipoprotein D modulates amyloid pathology in APP/PS1 Alzheimer's disease mice

scientific article published on 19 February 2015

Assessment of diets containing curcumin, epigallocatechin-3-gallate, docosahexaenoic acid and α-lipoic acid on amyloid load and inflammation in a male transgenic mouse model of Alzheimer's disease: Are combinations more effective?

scientific article published on 02 January 2019

Behavioral effects of neuropeptide Y in F344 rat substrains with a reduced dipeptidyl-peptidase IV activity

scientific article published in July 2003

Behavioral phenotyping of mice in pharmacological and toxicological research

scientific article

Behavioral profile of a heterozygous mutant mouse model for EGF-like domain neuregulin 1.

scientific article published on August 2008

Behavioral profiling of NPY in aggression and neuropsychiatric diseases

scientific article published on 28 December 2006

Behavioural characteristics of the Prader-Willi syndrome related biallelic Snord116 mouse model

scientific article

Behavioural consequences of IVC cages on male and female C57BL/6J mice

scientific article published on 14 February 2013

Behavioural effects of chronic haloperidol and risperidone treatment in rats

scientific article published on 11 May 2006

Behavioural effects of high fat diet exposure starting in late adolescence in neuregulin 1 transmembrane domain mutant mice

scientific article published on 05 July 2019

Behavioural effects of high fat diet in a mutant mouse model for the schizophrenia risk gene neuregulin 1.

scientific article published on 26 December 2015

Behavioural effects of high fat diet in adult Nrg1 type III transgenic mice

scientific article published on 06 September 2019

Behavioural profile of a new mouse model for NPY deficiency

scientific article published in July 2008

Cannabidiol (CBD) reduces anxiety-related behavior in mice via an FMRP-independent mechanism

scientific article published on 04 May 2019

Cannabidiol potentiates Δ⁹-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats.

scientific article

Cerebral Apolipoprotein-D Is Hypoglycosylated Compared to Peripheral Tissues and Is Variably Expressed in Mouse and Human Brain Regions

scientific article published in February 2016

Chronic Microglial Activation in the GFAP-IL6 Mouse Contributes to Age-Dependent Cerebellar Volume Loss and Impairment in Motor Function

scientific article published on 03 April 2019

Chronic cannabidiol treatment improves social and object recognition in double transgenic APPswe/PS1∆E9 mice

scientific article

Cognition in female transmembrane domain neuregulin 1 mutant mice

scientific article

Cognition in transmembrane domain neuregulin 1 mutant mice

scientific article

Cognitive phenotyping of amyloid precursor protein transgenic J20 mice

scientific article published on 19 December 2011

Contextual fear conditioning is enhanced in mice lacking functional sphingosine kinase 2.

scientific article published on 15 June 2017

Cross-Linking Cellular Prion Protein Induces Neuronal Type 2-Like Hypersensitivity

scientific article published on 30 July 2021

Deletion of Abca7 increases cerebral amyloid-β accumulation in the J20 mouse model of Alzheimer's disease

scientific journal article

Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling

scientific article published in Nature Communications

Disinhibition-like behavior in a P301S mutant tau transgenic mouse model of frontotemporal dementia

scientific article published on 10 August 2016

Distinct endocrine effects of chronic haloperidol or risperidone administration in male rats

Distinct neurobehavioural effects of cannabidiol in transmembrane domain neuregulin 1 mutant mice

scientific article

Do individually ventilated cage systems generate a problem for genetic mouse model research?

scientific article published on 23 July 2014

Do transmembrane domain neuregulin 1 mutant mice exhibit a reliable sensorimotor gating deficit?

scientific article published on 13 May 2011

Dynorphin knockout reduces fat mass and increases weight loss during fasting in mice

scientific article

Effect of Y1 receptor deficiency on motor activity, exploration, and anxiety

scientific article published on 3 October 2005

Effect of maternal immune activation on the kynurenine pathway in preadolescent rat offspring and on MK801-induced hyperlocomotion in adulthood: amelioration by COX-2 inhibition

scientific article published on 27 May 2014

Effects of chronic risperidone treatment on the striatal protein profiles in rats

scientific article published on 30 August 2006

Effects of handling on the behavioural phenotype of the neuregulin 1 type III transgenic mouse model for schizophrenia

scientific article published on 15 February 2021

Extreme reduction of dipeptidyl peptidase IV activity in F344 rat substrains is associated with various behavioral differences

scientific article published in October 2003

Female neuregulin 1 heterozygous mice require repeated exposure to Δ⁹-tetrahydrocannabinol to alter sensorimotor gating function

scientific article published on 8 October 2013

First Behavioural Characterisation of a Knockout Mouse Model for the Transforming Growth Factor (TGF)-β Superfamily Cytokine, MIC-1/GDF15

scientific article

First behavioural assessment of a novel Immp2l knockdown mouse model with relevance for Gilles de la Tourette syndrome and Autism spectrum disorder

scientific article published on 21 June 2019

Genetic Rat Models for Schizophrenia

Heterozygous neuregulin 1 mice are more sensitive to the behavioural effects of Delta9-tetrahydrocannabinol

scientific article published on 28 February 2007

Heterozygous neuregulin 1 mice display greater baseline and Delta(9)-tetrahydrocannabinol-induced c-Fos expression.

scientific article published on 28 August 2007

In vivo Evidence for Therapeutic Properties of Cannabidiol (CBD) for Alzheimer's Disease

scientific article published on 03 February 2017

Increased levels of serotonin 2A receptors and serotonin transporter in the CNS of neuregulin 1 hypomorphic/mutant mice

scientific article published on 28 November 2007

Localization, transmission, spontaneous mutations, and variation of function of the Dpp4 (Dipeptidyl-peptidase IV; CD26) gene in rats

scientific article published in September 2003

Long-term behavioural effects of maternal obesity in C57BL/6J mice

scientific article published on 08 November 2018

Long-term cannabidiol treatment prevents the development of social recognition memory deficits in Alzheimer's disease transgenic mice

scientific article published in January 2014

Mouse models of frontotemporal dementia: A comparison of phenotypes with clinical symptomatology

scientific article published on 11 January 2017

Neuregulin 1 Deficiency Modulates Adolescent Stress-Induced Dendritic Spine Loss in a Brain Region-Specific Manner and Increases Complement 4 Expression in the Hippocampus.

scientific article published on 16 March 2018

Neuregulin 1 Prevents Phencyclidine-Induced Behavioral Impairments and Disruptions to GABAergic Signaling in Mice

scientific article (publication date: 25 December 2014)

Neuregulin 1 expression and electrophysiological abnormalities in the Neuregulin 1 transmembrane domain heterozygous mutant mouse

scientific article published on 19 May 2015

Neuregulin 1 hypomorphic mutant mice: enhanced baseline locomotor activity but normal psychotropic drug-induced hyperlocomotion and prepulse inhibition regulation.

scientific article published on 29 April 2009

Neuregulin 1: a prime candidate for research into gene-environment interactions in schizophrenia? Insights from genetic rodent models ⬇️

scientific article published on August 15, 2013

Neuregulin-1 and schizophrenia in the genome-wide association study era.

scientific article published on 6 June 2016

Neuropeptide Y (NPY) cleaving enzymes: structural and functional homologues of dipeptidyl peptidase 4.

scientific article

Neuropeptide y attenuates stress-induced bone loss through suppression of noradrenaline circuits

scientific article published in October 2014

Novel behavioural characteristics of female APPSwe/PS1ΔE9 double transgenic mice

scientific article

Novel behavioural characteristics of the APP(Swe)/PS1ΔE9 transgenic mouse model of Alzheimer's disease

scientific article

Novel behavioural characteristics of the superoxide dismutase 1 G93A (SOD1G93A ) mouse model of amyotrophic lateral sclerosis include sex-dependent phenotypes

scientific article published on 10 September 2019

Novel molecular changes induced by Nrg1 hypomorphism and Nrg1-cannabinoid interaction in adolescence: a hippocampal proteomic study in mice

scientific article published on 26 February 2013

Obesity and the associated mediators leptin, estrogen and IGF-I enhance the cell proliferation and early tumorigenesis of breast cancer cells

scientific article published on January 2009

Parent-of-origin effects on schizophrenia-relevant behaviours of type III neuregulin 1 mutant mice

scientific article published on 31 May 2017

Partial genetic deletion of neuregulin 1 modulates the effects of stress on sensorimotor gating, dendritic morphology, and HPA axis activity in adolescent mice

scientific article

Peptide YY ablation in mice leads to the development of hyperinsulinaemia and obesity

scientific article

Reduced type III neuregulin 1 expression does not modulate the behavioural sensitivity of mice to acute Δ9-tetrahydrocannabinol (D9-THC)

scientific article published on 08 May 2018

Role of Abca7 in mouse behaviours relevant to neurodegenerative diseases

scientific article

Schizophrenia-relevant behaviours in a genetic mouse model for Y2 deficiency

scientific article published on 30 October 2009

Schizophrenia-relevant behaviours of female mice overexpressing neuregulin 1 type III.

scientific article published on 17 March 2018

Schizophrenia: a consequence of gene-environment interactions?

scientific article published on 23 December 2014

Septal Glucagon-Like Peptide 1 Receptor Expression Determines Suppression of Cocaine-Induced Behavior

scientific article published on 11 February 2015

Sphingosine Kinase 2 Potentiates Amyloid Deposition but Protects against Hippocampal Volume Loss and Demyelination in a Mouse Model of Alzheimer's Disease

scientific article published on 22 October 2019

Stress-induced hyperthermia in the rat: comparison of classical and novel recording methods

scientific article published on 01 April 2006

Targeting Inflammatory Pathways in Alzheimer's Disease: A Focus on Natural Products and Phytomedicines

scientific article published on 01 May 2019

Testosterone attenuates and the selective estrogen receptor modulator, raloxifene, potentiates amphetamine-induced locomotion in male rats

scientific article

The Endocannabinoid System across Postnatal Development in Transmembrane Domain Neuregulin 1 Mutant Mice

scientific article published on 7 February 2018

The Interactive Nature of Cannabis and Schizophrenia Risk Genes

article

The response of neuregulin 1 mutant mice to acute restraint stress

article

The schizophrenia susceptibility gene neuregulin 1 modulates tolerance to the effects of cannabinoids

scientific article published on 12 August 2010

The therapeutic potential of the endocannabinoid system for Alzheimer's disease

scientific article published on 27 March 2012

The therapeutic potential of the phytocannabinoid cannabidiol for Alzheimer's disease

scientific article published on 28 July 2016

Transmembrane domain Nrg1 mutant mice show altered susceptibility to the neurobehavioural actions of repeated THC exposure in adolescence

scientific article published on 9 January 2012

Treatment of microglia with Anti-PrP monoclonal antibodies induces neuronal apoptosis in vitro

Understanding the function of ABCA7 in Alzheimer's disease

scientific article

Upregulation of Proteolytic Pathways and Altered Protein Biosynthesis Underlie Retinal Pathology in a Mouse Model of Alzheimer's Disease

scientific article published on 01 February 2019

What does a mouse tell us about neuregulin 1-cannabis interactions?

scientific article published on 26 February 2013

Y1 receptors are critical for the proliferation of adult mouse precursor cells in the olfactory neuroepithelium

scientific article

Y1 receptors regulate aggressive behavior by modulating serotonin pathways

scholarly article

Y2Y4 receptor double knockout protects against obesity due to a high-fat diet or Y1 receptor deficiency in mice

scientific article published in January 2006

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