Search filters

List of works by Anabela Cordeiro-da-Silva

A Leishmania infantum cytosolic tryparedoxin activates B cells to secrete interleukin-10 and specific immunoglobulin

scientific article published on 17 November 2007

A method for functional mouse MDR3 P-glycoprotein reconstitution in Escherichia coli lipids.

scientific article

A role for hepcidin in the anemia caused by Trypanosoma brucei infection

scientific article published on 09 January 2020

AMP-activated Protein Kinase As a Target For Pathogens: Friends Or Foes?

scientific article published on 16 April 2015

Abortive T follicular helper development is associated with a defective humoral response in Leishmania infantum-infected macaques

scientific article

Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform

scientific article published on 01 March 2019

Activity of Bisnaphthalimidopropyl Derivatives against Trypanosoma brucei

scientific article published on 19 January 2016

Alginate coated chitosan nanoparticles are an effective subcutaneous adjuvant for hepatitis B surface antigen

scientific article

Anti-Leishmania humoral and cellular immune responses in naturally infected symptomatic and asymptomatic dogs

article

Anti-leishmanial activity of the bisnaphthalimidopropyl derivatives

scientific article published on 6 December 2011

Antibodies against a Leishmania infantum peroxiredoxin as a possible marker for diagnosis of visceral leishmaniasis and for monitoring the efficacy of treatment

scientific article published on 26 April 2005

Antileishmanial Drugs Modulate IL-12 Expression and Inflammasome Activation in Primary Human Cells

scientific article published on 04 March 2020

Application of an improved enzyme-linked immunosorbent assay method for serological diagnosis of canine leishmaniasis

scientific article

Aryl thiosemicarbazones for the treatment of trypanosomatidic infections

scientific article published on 30 January 2018

Author Correction: Challenges in the serological evaluation of dogs clinically suspect for canine leishmaniasis

scientific article published on 28 May 2020

Benzodiazepine-mediated structural changes in the multidrug transporter P-glycoprotein: an intrinsic fluorescence quenching analysis

scientific article

Biological properties of extracellular vesicles and their physiological functions.

scientific article published on 14 May 2015

Bisnaphthalimidopropyl derivatives as inhibitors of Leishmania SIR2 related protein 1.

scientific article

Canine visceral leishmaniasis: Diagnosis and management of the reservoir living among us.

scientific article

Challenges in the serological evaluation of dogs clinically suspect for canine leishmaniasis

scientific article published on 20 February 2020

Characterization and evaluation of BNIPDaoct-loaded PLGA nanoparticles for visceral leishmaniasis: in vitro and in vivo studies

scientific article

Characterization of 2,4-Diamino-6-oxo-1,6-dihydropyrimidin-5-yl Ureido Based Inhibitors of Trypanosoma brucei FolD and Testing for Antiparasitic Activity

scientific article

Characterization of Leishmania infantum thiol-dependent reductase 1 and evaluation of its potential to induce immune protection

scientific article published on 01 June 2012

Characterization of the anti-Leishmania effect induced by cisplatin, an anticancer drug

scientific article published on 2 June 2007

Characterization of the biology and infectivity of Leishmania infantum viscerotropic and dermotropic strains isolated from HIV+ and HIV- patients in the murine model of visceral leishmaniasis

scientific article published on 26 April 2013

Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity.

scientific article published on 8 March 2017

Complementary antioxidant defense by cytoplasmic and mitochondrial peroxiredoxins in Leishmania infantum

scientific article

Conversion of Trypanosoma cruzi Tc52 released factor to a protein inducing apoptosis.

scientific article published on 24 October 2005

Correction: Knockdown of Asparagine Synthetase A Renders Trypanosoma brucei Auxotrophic to Asparagine

scholarly article by Inês Loureiro et al published 6 December 2013 in PLoS Neglected Tropical Diseases

Crucial CD8(+) T-lymphocyte cytotoxic role in amphotericin B nanospheres efficacy against experimental visceral leishmaniasis

scientific article published on 8 January 2014

Current and Future Chemotherapy for Chagas Disease

scientific article published on 19 October 2015

Deception and manipulation: the arms of leishmania, a successful parasite

scientific article

Development and validation of HPLC method with fluorometric detection for quantification of bisnaphthalimidopropyldiaminooctane in animal tissues following administration in polymeric nanoparticles

scientific article published on 22 December 2015

Development of a fluorescent based immunosensor for the serodiagnosis of canine leishmaniasis combining immunomagnetic separation and flow cytometry.

scientific article

Differential effects of polyamine derivative compounds against Leishmania infantum promastigotes and axenic amastigotes

scientific article published on 11 March 2005

Differential roles of PI3-Kinase, MAPKs and NF-kappaB on the manipulation of dendritic cell T(h)1/T(h)2 cytokine/chemokine polarizing profile

scientific article

Disclosing the essentiality of ribose-5-phosphate isomerase B in Trypanosomatids

scientific article published on 27 May 2016

Discovery of a benzothiophene-flavonol halting miltefosine and antimonial drug resistance in Leishmania parasites through the application of medicinal chemistry, screening and genomics

scientific article published on 05 September 2019

Drug discovery for human African trypanosomiasis: identification of novel scaffolds by the newly developed HTS SYBR Green assay for Trypanosoma brucei

scientific article

Dual role of the Leishmania major ribosomal protein S3a homologue in regulation of T- and B-cell activation.

scientific article published on November 2001

Effect of abietane diterpenes from Plectranthus grandidentatus on T- and B-lymphocyte proliferation.

scientific article published in January 2004

Effect of anti-inflammatory drugs on splenocyte membrane fluidity.

scientific article

Effect of colchicine on P-glycoprotein expression and activity in Caco2 cells

Effect of nonsteroidal anti-inflammatory drugs on the cellular membrane fluidity

scientific article published on August 2008

Enantiomers of nifurtimox do not exhibit stereoselective anti-Trypanosoma cruzi activity, toxicity, or pharmacokinetic properties

scientific article published on 6 April 2015

Endogenous Trypanosoma cruzi Tc52 protein expression upregulates the growth of murine macrophages and fibroblasts and cytokine gene expression.

scientific article

Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections

scientific article published on 09 April 2019

Evaluating the Role of Host AMPK in Leishmania Burden.

scientific article

Evaluation of the immune response following a short oral vaccination schedule with hepatitis B antigen encapsulated into alginate-coated chitosan nanoparticles

article

Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine

scientific article

Exoproteome dynamics in Leishmania infantum

scientific article

Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery.

scientific article published on 11 September 2017

Flurazepam inhibits the P-glycoprotein transport function: an insight to revert multidrug-resistance phenotype.

scientific article published on 28 November 2007

Host Cell Phenotypic Variability Induced by Trypanosomatid-Parasite-Released Immunomodulatory Factors: Physiopathological Implications

scientific article

Human periprostatic white adipose tissue is rich in stromal progenitor cells and a potential source of prostate tumor stroma

scientific article published on 04 October 2012

Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign

scientific article published on 10 January 2020

Identification of antibodies to Leishmania silent information regulatory 2 (SIR2) protein homologue during canine natural infections: pathological implications.

scientific article published in April 2003

Immune response by nasal delivery of hepatitis B surface antigen and codelivery of a CpG ODN in alginate coated chitosan nanoparticles

article

Immune response regulation by leishmania secreted and nonsecreted antigens

scientific article published on January 2007

Immunological alterations induced by polyamine derivatives on murine splenocytes and human mononuclear cells

scientific article published in April 2004

Impact of continuous axenic cultivation in Leishmania infantum virulence

scientific article

Impairment of T cell function in parasitic infections

scientific article

In Vitro Infections of Macrophage-Like Cell Lines with Leishmania infantum for Drug Screening

scientific article published on 01 January 2019

In vitro and in vivo anticancer activity of a novel nano-sized formulation based on self-assembling polymers against pancreatic cancer

scientific article published on 25 September 2010

In vitro study of P-glycoprotein induction as an antidotal pathway to prevent cytotoxicity in Caco-2 cells ⬇️

scientific article published on September 21, 2010

In vivo imaging of pathogen homing to the host tissues

scientific article published on 15 May 2017

Induction of lymphocytes activated marker CD69 following exposure to chitosan and alginate biopolymers

scientific article published on 20 January 2007

Infection of hematopoietic stem cells by Leishmania infantum increases erythropoiesis and alters the phenotypic and functional profiles of progeny

scientific article published on 7 November 2017

Influence of aging and prostatic disease in the expression and activity of P-glycoprotein in human lymphocytes

Inhibition of lymphocyte proliferation by prenylated flavones: artelastin as a potent inhibitor.

scientific article published on September 2003

Inhibitors of Trypanosoma cruzi Sir2 related protein 1 as potential drugs against Chagas disease.

scientific article

Interleukin-27 Early Impacts Leishmania infantum Infection in Mice and Correlates with Active Visceral Disease in Humans.

scientific article

Knockdown of asparagine synthetase A renders Trypanosoma brucei auxotrophic to asparagine

scientific article (publication date: 2013)

Leishmania cytosolic silent information regulatory protein 2 deacetylase induces murine B-cell differentiation and in vivo production of specific antibodies

article

Leishmania infantum Asparagine Synthetase A Is Dispensable for Parasites Survival and Infectivity

scientific article

Leishmania infantum Exoproducts Inhibit Human Invariant NKT Cell Expansion and Activation

scientific article

Leishmania infantum MON-98: infection in a dog from Alto Douro, Portugal

scientific article published in July 2002

Leishmania infantum modulates host macrophage mitochondrial metabolism by hijacking the SIRT1-AMPK axis

scientific article

Leishmania-infected MHC class IIhigh dendritic cells polarize CD4+ T cells toward a nonprotective T-bet+ IFN-γ+ IL-10+ phenotype

scientific article published on 31 May 2013

Live attenuated Leishmania vaccines: a potential strategic alternative

scientific article published on 31 March 2008

Metabolic Crosstalk Between Host and Parasitic Pathogens

scientific article published on 01 January 2018

Metabolic variation during development in culture of Leishmania donovani promastigotes

scientific article

Methoxylated 2'-hydroxychalcones as antiparasitic hit compounds.

scientific article

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

scientific article published on 23 November 2018

Modulation of mammalian apoptotic pathways by intracellular protozoan parasites.

scientific article published on 09 February 2012

Molecular karyotype analysis of Perkinsus atlanticus (Phylum Perkinsozoa) by pulsed field gel electrophoresis

scientific article published on 05 September 2007

More than just exosomes: distinct extracellular products potentiate the establishment of infection

scientific article published on 08 November 2018

Murine infection with bioluminescent Leishmania infantum axenic amastigotes applied to drug discovery

scientific article published on 12 December 2019

P-glycoprotein activity in human Caucasian male lymphocytes does not follow its increased expression during aging

scientific article published on 8 September 2011

P-glycoprotein induction as a cellular protection tool against xenobiotics toxicity

Poly-N-Acetylglucosamine Production by Staphylococcus epidermidis Cells Increases Their In Vivo Proinflammatory Effect

scientific article published on August 2016

Potential drug targets in the pentose phosphate pathway of trypanosomatids

scientific article

Pre-clinical antigenicity studies of an innovative multivalent vaccine for human visceral leishmaniasis

scientific article published on 27 November 2017

Prevalence of antibodies to Leishmania infantum and Toxoplasma gondii in horses from the north of Portugal

scientific article published on 17 June 2013

Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs

scientific article

Proinflammatory environment dictates the IL-17-producing capacity of human invariant NKT cells.

scientific article

Quantification of Leishmania Parasites in Murine Models of Visceral Infection

scientific article published on 01 January 2019

Rapamycin combined with TGF-β converts human invariant NKT cells into suppressive Foxp3+ regulatory cells

scientific article published on 12 December 2011

Recognition of Leishmania Parasites by Innate Immunity

Regulation of immunity during visceral Leishmania infection

scientific article

SAR Studies and Biological Characterization of a Chromen-4-one Derivative as an Anti-Trypanosoma brucei Agent

scientific article published on 29 January 2019

Sensitivity of P-glycoprotein tryptophan residues to benzodiazepines and ATP interaction

scientific article published on 22 July 2006

Serological evaluation of experimentally infected dogs by LicTXNPx–ELISA and amastigote-flow cytometry

scientific article published on 06 September 2008

Solid lipid nanoparticles as intracellular drug transporters: an investigation of the uptake mechanism and pathway.

scientific article

Structural Insights into the Development of Cycloguanil Derivatives as Trypanosoma brucei Pteridine-Reductase-1 Inhibitors

scientific article published on 01 May 2019

Structure Function Analysis of Leishmania Sirtuin: An Ensemble of In Silico and Biochemical Studies

article

Surface functionalization of polymeric nanospheres modulates macrophage activation: relevance in leishmaniasis therapy

scientific article published on February 2015

TLR2-induced IL-10 production impairs neutrophil recruitment to infected tissues during neonatal bacterial sepsis

scientific article published on 27 September 2013

Targeted disruption of cytosolic SIR2 deacetylase discloses its essential role in Leishmania survival and proliferation

scientific article published on 19 October 2005

The Leishmania infantum cytosolic SIR2-related protein 1 (LiSIR2RP1) is an NAD+ -dependent deacetylase and ADP-ribosyltransferase

scientific article published in November 2008

The Leishmania nicotinamidase is essential for NAD+ production and parasite proliferation

scientific article

The Use of Specific Serological Biomarkers to Detect CaniLeish Vaccination in Dogs

scientific article published on 24 October 2019

The anti-caspase inhibitor Q-VD-OPH prevents AIDS disease progression in SIV-infected rhesus macaques.

scientific article

The contribution of Toll-like receptor 2 to the innate recognition of a Leishmania infantum silent information regulator 2 protein.

scientific article

The crystal structure of the Leishmania infantum Silent Information Regulator 2 related protein 1: Implications to protein function and drug design.

scientific article published on 15 March 2018

The impact of distinct culture media in Leishmania infantum biology and infectivity

scientific article published on 6 September 2013

Therapy and Further Development of Anti-Leishmanial Drugs

article

Trypanosoma cruzi carrying a targeted deletion of a Tc52 protein-encoding allele elicits attenuated Chagas' disease in mice

Two linked genes of Leishmania infantum encode tryparedoxins localised to cytosol and mitochondrion.

scientific article published in August 2004

Understanding Resistance vs. Susceptibility in Visceral Leishmaniasis Using Mouse Models of Infection

scientific article published on 01 March 2019

Uptake studies in rat Peyer's patches, cytotoxicity and release studies of alginate coated chitosan nanoparticles for mucosal vaccination

scientific article published on 16 June 2006

Visceral Dissemination of Mucocutaneous Leishmaniasis in a Kidney Transplant Recipient

scientific article published on 30 December 2020

Paulina is supported by:

About Paulina

Help