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List of works by Matthew J. Sweet

A CSF-1 receptor kinase inhibitor targets effector functions and inhibits pro-inflammatory cytokine production from murine macrophage populations

scientific article published on 28 July 2006

A conserved distal segment of the mouse CSF-1 receptor promoter is required for maximal expression of a reporter gene in macrophages and osteoclasts of transgenic mice

article

A sprinkle of salt in the pressure cooker of innate immunity and inflammation

scientific article published on 03 November 2020

Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction

scientific article

An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice.

scientific article published on 8 November 2016

An alloy of zinc and innate immunity: galvanizing host defence against infection

scientific article published on 25 September 2020

An antioxidant role for catecholate siderophores in Salmonella.

scientific article published on September 2013

An mRNA atlas of G protein-coupled receptor expression during primary human monocyte/macrophage differentiation and lipopolysaccharide-mediated activation identifies targetable candidate regulators of inflammation.

scientific article

Analysis of the N-terminal region of human MLKL, as well as two distinct MLKL isoforms, reveals new insights into necroptotic cell death

scientific article

B cells do not take up bacterial DNA: an essential role for antigen in exposure of DNA to toll-like receptor-9.

scientific article published on 5 October 2010

Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival

scientific article published on 26 September 2009

CAT2-mediated L-arginine transport and nitric oxide production in activated macrophages.

scientific article published on June 1999

Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of the TIR domain from the Brucella melitensis TIR-domain-containing protein TcpB.

scientific article published on 28 September 2013

Co-transcriptomic Analysis by RNA Sequencing to Simultaneously Measure Regulated Gene Expression in Host and Bacterial Pathogen

scientific article

Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages

scientific article

Complex Multilevel Control of Hemolysin Production by Uropathogenic Escherichia coli

scientific article published on 01 October 2019

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages

scientific article

Copper redistribution in murine macrophages in response to Salmonella infection

scientific article published on May 2012

Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection

scientific article

Crystallization and X-ray diffraction analysis of the N-terminal domain of the Toll-like receptor signalling adaptor protein TRIF/TICAM-1.

scientific article published on 28 June 2013

Dead cells certainly do matter, particularly when they can speak from the grave

scientific article published in December 2010

Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice

scientific article published on 26 June 2015

Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury

scientific article

Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D(2) synthases.

scientific article published on August 2010

Development of SH2 probes and pull-down assays to detect pathogen-induced, site-specific tyrosine phosphorylation of the TLR adaptor SCIMP.

scientific article published on 14 March 2017

Differences in the repertoire, regulation and function of Toll-like Receptors and inflammasome-forming Nod-like Receptors between human and mouse.

scientific article published on 26 March 2013

Differential Anti-inflammatory Activity of HDAC Inhibitors in Human Macrophages and Rat Arthritis

scientific article published on 10 December 2015

Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS.

scientific article published on 3 March 2010

Experimental and bioinformatic characterisation of the promoter region of the Marfan syndrome gene, FBN1.

scientific article

Expression analysis of G Protein-Coupled Receptors in mouse macrophages

scientific article

For when bacterial infections persist: Toll-like receptor-inducible direct antimicrobial pathways in macrophages.

scientific article published on 3 January 2018

Frontline Science: LPS-inducible SLC30A1 drives human macrophage-mediated zinc toxicity against intracellular Escherichia coli

scientific article published on 22 May 2020

G-protein-coupled receptor expression, function, and signaling in macrophages

scientific article published on 24 April 2007

Genetic control of the innate immune response

scientific article

Genome-Wide Discovery of Genes Required for Capsule Production by Uropathogenic Escherichia coli

scientific article published on 24 October 2017

Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP.

scientific article published on 17 May 2018

Group A streptococcal pharyngitis: immune responses involved in bacterial clearance and GAS-associated immunopathologies

scientific article published on 26 September 2017

HDAC inhibitors: modulating leukocyte differentiation, survival, proliferation and inflammation.

scientific article published on 25 October 2011

HDACs and their inhibitors in immunology: teaching anticancer drugs new tricks

scientific article published on 01 January 2012

HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA

scientific journal article

HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi

scientific article published on 23 July 2015

Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes

article

Histone Deacetylase Inhibitors Promote Mitochondrial Reactive Oxygen Species Production and Bacterial Clearance by Human Macrophages.

scientific article published on 28 December 2015

Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages

scientific article

Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment

article

Histone deacetylase inhibitors in inflammatory disease.

scientific article published on January 2009

Histone deacetylases as regulators of inflammation and immunity ⬇️

scientific article published on May 12, 2011

Histone deacetylases in monocyte/macrophage development, activation and metabolism: refining HDAC targets for inflammatory and infectious diseases

scientific article

Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis

scientific article published on 01 June 2019

Identification and characterization of a new family of cell-penetrating peptides: cyclic cell-penetrating peptides

scientific article

In life there is death: How epithelial tissue barriers are preserved despite the challenge of apoptosis.

scientific article published on 28 June 2017

Inflammatory responses induced by lipopolysaccharide are amplified in primary human monocytes but suppressed in macrophages by complement protein C5a.

scientific article published on 16 September 2013

Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1-Independent Mechanism.

scientific article published on 30 October 2015

Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic type 2 inflammation

scientific article published on 17 August 2019

Inhibitors selective for HDAC6 in enzymes and cells ⬇️

scientific article published on October 12, 2010

Innate immune perturbations, accumulating DAMPs and inflammasome dysregulation: A ticking time bomb in ageing

scientific article published on 25 February 2015

Interferon regulatory factor 6 differentially regulates Toll-like receptor 2-dependent chemokine gene expression in epithelial cells.

scientific article

Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion

scientific article published on 01 August 2018

Intramacrophage survival of uropathogenic Escherichia coli: differences between diverse clinical isolates and between mouse and human macrophages

scientific article published on 24 May 2011

LPS regulates a set of genes in primary murine macrophages by antagonising CSF-1 action

scientific article

LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression

scientific article published on July 2006

Lipopolysaccharide promotes Drp1-dependent mitochondrial fission and associated inflammatory responses in macrophages

scientific article published on 20 July 2020

Lysine Deacetylases and Regulated Glycolysis in Macrophages.

scientific article

Macrophage activation and differentiation signals regulate schlafen-4 gene expression: evidence for Schlafen-4 as a modulator of myelopoiesis

scientific article

Macrophage secretory products induce an inflammatory phenotype in hepatocytes

scientific article published in April 2012

Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense

scientific article published on 01 October 2020

Mechanism of Bacterial Interference with TLR4 Signaling by Brucella Toll/Interleukin-1 Receptor Domain-containing Protein TcpB

scientific article

Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copper

scientific article published on 16 July 2013

Minocycline Prevents the Development of Mechanical Allodynia in Mouse Models of Vincristine-Induced Peripheral Neuropathy

scientific article published on 27 June 2019

Nicotinamide riboside attenuates age-associated metabolic and functional changes in hematopoietic stem cells

scientific article published on 11 May 2021

Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps

scientific article published on 01 August 2018

Opposing actions of c-ets/PU.1 and c-myb protooncogene products in regulating the macrophage-specific promoters of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes.

scientific article

Osteal macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model

scientific article

PU.1 and ICSBP control constitutive and IFN-gamma-regulated Tlr9 gene expression in mouse macrophages

scientific article

Phosphoinositide 3-kinase δ regulates membrane fission of Golgi carriers for selective cytokine secretion ⬇️

scientific article

Portal, but not lobular, macrophages express matrix metalloproteinase-9: association with the ductular reaction and fibrosis in chronic hepatitis C

scientific article published on 13 December 2012

Protective role for Toll-like receptor-9 in the development of atherosclerosis in apolipoprotein E-deficient mice

scientific article published on 16 January 2014

Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling

scientific article

Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists.

scientific article

Receptor-interacting protein kinase 4 and interferon regulatory factor 6 function as a signaling axis to regulate keratinocyte differentiation

scientific article

Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4

article

Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages.

scientific article

Regulation of the endosomal SNARE protein syntaxin 7 by colony-stimulating factor 1 in macrophages

scientific article published on 18 August 2008

SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages

scientific article published on 18 January 2017

SCIMP is a universal Toll-like receptor adaptor in macrophages

scientific article published on 29 August 2019

Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages

scientific article published on 2 February 2016

Selective induction of the Notch ligand Jagged-1 in macrophages by soluble egg antigen from Schistosoma mansoni involves ERK signalling.

scientific article

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration

scientific article

Signal integration between IFNgamma and TLR signalling pathways in macrophages

scientific article published on 5 July 2006

Small GTPase Rab8a-recruited Phosphatidylinositol 3-Kinase γ Regulates Signaling and Cytokine Outputs from Endosomal Toll-like Receptors.

scientific article published on 27 January 2017

Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli

scientific article

T1/ST2--an IL-1 receptor-like modulator of immune responses.

scientific article published on April 2004

TLR3 drives IRF6-dependent IL-23p19 expression and p19/EBI3 heterodimer formation in keratinocytes

scientific article published on 25 August 2015

TLR9-independent effects of inhibitory oligonucleotides on macrophage responses to S. typhimurium

scientific article

TRIF-dependent TLR signaling, its functions in host defense and inflammation, and its potential as a therapeutic target

scientific article published on 9 May 2016

The Australian Toll-way gets the Nod--meeting report of TLROZ 2007: pattern recognition receptors in immunity and disease, Melbourne, Australia, 16-18th May 2007.

scientific article published on 17 July 2007

The E3 ubiquitin ligase RNF144B is LPS-inducible in human, but not mouse, macrophages and promotes inducible IL-1β expression

scientific article published on 27 January 2016

The TLR signalling adaptor TRIF/TICAM-1 has an N-terminal helical domain with structural similarity to IFIT proteins

scientific article

The co-transcriptome of uropathogenic Escherichia coli-infected mouse macrophages reveals new insights into host-pathogen interactions

scientific article published on 24 January 2015

The cytochrome bd-I respiratory oxidase augments survival of multidrug-resistant Escherichia coli during infection.

scientific article published on 21 October 2016

The immunostimulatory activity of phosphorothioate CpG oligonucleotides is affected by distal sequence changes

scientific article published on 16 February 2011

The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimer

scientific article published on 17 May 2012

The mammalian PYHIN gene family: phylogeny, evolution and expression

scientific article (publication date: 7 August 2012)

The multi-copper-ion oxidase CueO of Salmonella enterica serovar Typhimurium is required for systemic virulence

scientific article

The murine neutrophil NLRP3 inflammasome is activated by soluble but not particulate or crystalline agonists

scientific article published on February 2016

The neutrophil NLRC4 inflammasome selectively promotes IL-1β maturation without pyroptosis during acute Salmonella challenge

scientific article published on 17 July 2014

The nicer side of innate immunity: Wound healing and tissue regeneration

scientific article published on 01 January 2017

The role of H4 flagella in Escherichia coli ST131 virulence

scientific article

The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized

scientific article

The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair.

scientific article published on 20 August 2016

The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line.

scientific article

Towards isozyme-selective HDAC inhibitors for interrogating disease.

scientific article published on January 2012

Towards selective lysophospholipid GPCR modulators

scientific article

Transcriptional network dynamics in macrophage activation

scientific article published on 12 May 2006

Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis

scientific article

Uropathogenic Escherichia coli Engages CD14-Dependent Signaling to Enable Bladder-Macrophage-Dependent Control of Acute Urinary Tract Infection.

scientific article published on 30 August 2015

Uropathogenic Escherichia coli virulence and innate immune responses during urinary tract infection

scientific article published on 08 February 2013

Uropathogenic employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination

article

Using the MCoTI-II Cyclotide Scaffold To Design a Stable Cyclic Peptide Antagonist of SET, a Protein Overexpressed in Human Cancer

scientific article published on 21 December 2015

Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization

scientific article published on 14 March 2019

pTRAPs: Transmembrane adaptors in innate immune signaling

scientific article

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