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List of works by Alexander Nyström

A Gene Gun-mediated Nonviral RNA trans-splicing Strategy for Col7a1 Repair.

scientific article published in March 2016

ADAM9 contributes to vascular invasion in pancreatic ductal adenocarcinoma

scientific article published on 09 January 2019

Analysis of the functional consequences of targeted exon deletion in COL7A1 reveals prospects for dystrophic epidermolysis bullosa therapy

scientific article published on 9 May 2016

Antisense Oligonucleotide-mediated Exon Skipping as a Systemic Therapeutic Approach for Recessive Dystrophic Epidermolysis Bullosa

scientific article

Balance and circumstance: The renin angiotensin system in wound healing and fibrosis

scientific article published on 30 July 2018

Basement membrane proteoglycans: modulators Par Excellence of cancer growth and angiogenesis.

scientific article published on 15 May 2009

Canonical TGFβ signaling induces collective invasion in colorectal carcinogenesis through a Snail1- and Zeb1-independent partial EMT

scientific article published on 24 January 2022

Cell therapy for basement membrane-linked diseases.

scientific article published on 5 September 2016

Cell- and protein-based therapy approaches for epidermolysis bullosa

scientific article published in January 2013

Cloning and Mutagenesis Strategies for Large Collagens

scientific article published on 01 January 2019

Collagen VII Half-Life at the Dermal-Epidermal Junction Zone: Implications for Mechanisms and Therapy of Genodermatoses.

scientific article published on 18 February 2016

Collagen VII deficient mice show morphologic and histologic corneal changes that phenotypically mimic human dystrophic epidermolysis bullosa of the eye

scientific article published on 18 June 2018

Collagen VII plays a dual role in wound healing

scientific article published on 8 July 2013

Collagen XVII Shedding Suppresses Re-Epithelialization by Directing Keratinocyte Migration and Dampening mTOR Signaling.

scientific article

Combinatorial omics analysis reveals perturbed lysosomal homeostasis in collagen VII-deficient keratinocytes.

scientific article published on 11 January 2018

Decorin counteracts disease progression in mice with recessive dystrophic epidermolysis bullosa

scientific article published on 05 December 2018

Distinct roles of integrins alpha6 and alpha4 in homing of fetal liver hematopoietic stem and progenitor cells

scientific article

Dynamic interactions of epidermal collagen XVII with the extracellular matrix: laminin 332 as a major binding partner

scientific article

Epidermal Basement Membrane in Health and Disease.

scientific article

Epidermolysis bullosa: Molecular pathology of connective tissue components in the cutaneous basement membrane zone

scientific article published on 05 April 2018

Extraocular muscle is spared upon complete laminin alpha2 chain deficiency: comparative expression of laminin and integrin isoforms.

scientific article published on 16 May 2006

Generation of a Functional Non-Shedding Collagen XVII Mouse Model: Relevance of Collagen XVII Shedding in Wound Healing

scientific article

Genetically corrected iPSCs as cell therapy for recessive dystrophic epidermolysis bullosa.

scientific article

High Local Concentrations of Intradermal MSCs Restore Skin Integrity and Facilitate Wound Healing in Dystrophic Epidermolysis Bullosa.

scientific article published on 10 April 2015

Identification of tissue damage, extracellular matrix remodeling and bacterial challenge as common mechanisms associated with high-risk cutaneous squamous cell carcinomas

scientific article published on 17 November 2017

Impaired lymphoid extracellular matrix impedes antibacterial immunity in epidermolysis bullosa

scientific article

Injury- and inflammation-driven skin fibrosis: The paradigm of epidermolysis bullosa.

scientific article published on 29 January 2018

Injury-Driven Stiffening of the Dermis Expedites Skin Carcinoma Progression.

scientific article published on 16 December 2015

Integrin alpha2beta1 is the required receptor for endorepellin angiostatic activity

scientific article published on 15 November 2007

Interaction of Complement Defence Collagens C1q and Mannose-Binding Lectin with BMP-1/Tolloid-like Proteinases.

scientific article published on 5 December 2017

Laminin isoforms in development and disease

scientific article

Laminin {alpha}1 chain corrects male infertility caused by absence of laminin {alpha}2 chain

scientific article published on September 2005

Large deletions targeting the triple-helical domain of collagen VII lead to mild acral dominant dystrophic epidermolysis bullosa.

scientific article published on 24 November 2017

Losartan ameliorates dystrophic epidermolysis bullosa and uncovers new disease mechanisms

scientific article

Matrix molecules and skin biology

scientific article published on 04 August 2018

One goal, different strategies – molecular and cellular approaches for the treatment of inherited skin fragility disorders

scientific article published on March 1, 2013

Pro-inflammatory immunity supports fibrosis advancement in epidermolysis bullosa: intervention with Ang-(1-7)

scientific article published on 30 August 2021

RNA-based therapies for genodermatoses

scientific article

Rat model for dominant dystrophic epidermolysis bullosa: glycine substitution reduces collagen VII stability and shows gene-dosage effect

scientific article

STAT3 targeting in dystrophic epidermolysis bullosa

scientific article published on 01 November 2019

The major basement membrane components localize to the chondrocyte pericellular matrix--a cartilage basement membrane equivalent?

scientific article published on 06 August 2007

The role of TGFβ in wound healing pathologies.

scientific article published on 10 November 2017

Therapies for genetic extracellular matrix diseases of the skin

scientific article published on 21 December 2017

Transmembrane collagens-Unexplored mediators of epidermal-dermal communication and tissue homeostasis

scientific article published on 31 August 2020

Treatment of keratinocytes with 4-phenylbutyrate in epidermolysis bullosa: Lessons for therapies in keratin disorders

scientific article published on 09 May 2019