List of works by Ronald Simon

19q13 amplification is associated with high grade and stage in pancreatic cancer

scientific article published on June 2010

A shift from membranous and stromal syndecan-1 (CD138) expression to cytoplasmic CD138 expression is associated with poor prognosis in breast cancer

scientific article published on 23 September 2019

AMACR expression in colorectal cancer is associated with left-sided tumor localization

scientific article published on 19 August 2008

Aberrant expression of membranous carbonic anhydrase IX (CAIX) is associated with unfavorable disease course in papillary and clear cell renal cell carcinoma

scientific article published on 12 October 2018

Aberrant expression of the microtubule-associated protein tau is an independent prognostic feature in prostate cancer

scientific article published on 01 March 2019

Amplification of the PPFIA1 gene region on 11q13 in oral squamous cell carcinomas (OSCC).

scientific article

Amplification pattern of 12q13-q15 genes (MDM2, CDK4, GLI) in urinary bladder cancer

scientific article published on 01 April 2002

Analysis of the progression of fibroepithelial tumours of the breast by PCR-based clonality assay

scientific article published on 01 August 2002

Applications of tissue microarray technology.

scientific article published on January 2010

Apurinic/apyrimidinic endonuclease 1 (APE1/Ref-1) overexpression is an independent prognostic marker in prostate cancer without TMPRSS2:ERG fusion.

scientific article published on 3 May 2017

Bladder cancer-associated protein, a potential prognostic biomarker in human bladder cancer.

scientific article

CCND1 amplification and cyclin D1 immunohistochemical expression in head and neck squamous cell carcinomas.

scientific article published on 15 March 2013

CD10 Expression Correlates with Earlier Tumour Stages and Left-Sided Tumour Location in Colorectal Cancer but Has No Prognostic Impact in a European Cohort

scientific article published in 2024

CHD1 is a 5q21 tumor suppressor required for ERG rearrangement in prostate cancer.

scientific article

Chromosome 5 harbors two independent deletion hotspots at 5q13 and 5q21 that characterize biologically different subsets of aggressive prostate cancer

scientific article published on 12 October 2020

Chromosome 8p deletions and 8q gains are associated with tumor progression and poor prognosis in prostate cancer

scientific article published on 22 December 2009

Clinical significance of epidermal growth factor receptor protein overexpression and gene copy number gains in prostate cancer

scientific article

Clinical significance of p53 alterations in surgically treated prostate cancers

scientific article published on 13 June 2008

Close association between HER-2 amplification and overexpression in human tumors of non-breast origin

scientific article published on 01 February 2007

Colorectal carcinoma from Saudi Arabia. Analysis of MLH-1, MSH-2 and p53 genes by immunohistochemistry and tissue microarray analysis

scientific article published on 01 March 2006

Cysteine-rich secretory protein 3 overexpression is linked to a subset of PTEN-deleted ERG fusion-positive prostate cancers with early biochemical recurrence

scientific article published on 30 November 2012

Deletions of chromosome 8p and loss of sFRP1 expression are progression markers of papillary bladder cancer

scientific article (publication date: April 2004)

Determination of PD-L1 Expression in Circulating Tumor Cells of NSCLC Patients and Correlation with Response to PD-1/PD-L1 Inhibitors

scientific article published on 17 June 2019

Development and Characterization of a Spontaneously Metastatic Patient-Derived Xenograft Model of Human Prostate Cancer

scientific article published in Scientific Reports

Discovery of Targetable Genetic Alterations in NSCLC Patients with Different Metastatic Patterns Using a MassARRAY-Based Circulating Tumor DNA Assay

scientific article published on 22 October 2020

Distinct gene expression profiles: nodal versus extranodal diffuse large B-cell lymphoma

scientific article published on 12 September 2008

E2F3 amplification and overexpression is associated with invasive tumor growth and rapid tumor cell proliferation in urinary bladder cancer

scientific article

ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy.

scientific article

EZH2 overexpression in head and neck cancer is related to lymph node metastasis

scientific article

Ectopic Expression of Hematopoietic SHIP1 in Human Colorectal Cancer

scientific article published on 15 July 2020

Epidermal growth factor receptor protein expression and genomic alterations in renal cell carcinoma

scientific article published in March 2012

Epithelial splicing regulatory protein 1 and 2 (ESRP1 and ESRP2) upregulation predicts poor prognosis in prostate cancer

scientific article published on 18 December 2020

Epstein-Barr virus infection is not the sole cause of high prevalence for Hodgkin's lymphoma in Saudi Arabia.

scientific article published in April 2006

Establishment and characterization of a new human pancreatic adenocarcinoma cell line with high metastatic potential to the lung

scientific article

Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer.

scientific article

Estrogen receptor gene amplification occurs rarely in ovarian cancer

scientific article published on 8 August 2008

Expression and amplification of therapeutic target genes in retinoblastoma

scientific article published on 10 November 2004

Expression and prognostic relevance of annexin A3 in prostate cancer

scientific article published on 16 January 2008

Expression of CCCTC-binding factor (CTCF) is linked to poor prognosis in prostate cancer

scientific article published on 29 November 2019

Expression of the immune checkpoint receptor TIGIT in Hodgkin's lymphoma

scientific article published on 04 December 2018

FISH Oracle: a web server for flexible visualization of DNA copy number data in a genomic context.

scientific article

Frequent homogeneous HER-2 amplification in primary and metastatic adenocarcinoma of the esophagus

scientific article published on 24 November 2006

Frequent intratumoral heterogeneity of EGFR gene copy gain in non-small cell lung cancer

scientific article published on 10 December 2012

Gene expression profiling of progressive papillary noninvasive carcinomas of the urinary bladder

scientific article

Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation.

scientific article published on 28 August 2012

Genomic Deletion of PTEN Is Associated with Tumor Progression and Early PSA Recurrence in ERG Fusion-Positive and Fusion-Negative Prostate Cancer

article

HDAC1 overexpression independently predicts biochemical recurrence and is associated with rapid tumor cell proliferation and genomic instability in prostate cancer.

scientific article published on 18 March 2015

HER-2 amplification is highly homogenous in gastric cancer.

scientific article published on 9 March 2009

HER-2 and TOP2A coamplification in urinary bladder cancer

scientific article

HER2 amplification in squamous cell carcinomas of the vulva

scientific article published on 28 February 2013

HER2 analysis in breast cancer: reduced immunoreactivity in FISH non-informative cancer biopsies

scientific article published on 01 December 2004

HER2, TOP2A, CCND1, EGFR and C-MYC oncogene amplification in colorectal cancer

scientific article published on August 2006

Heterogeneity of ERBB2 amplification in adenocarcinoma, squamous cell carcinoma and large cell undifferentiated carcinoma of the lung

scientific article published on 17 August 2012

Heterogeneity of ERG expression in prostate cancer: a large section mapping study of entire prostatectomy specimens from 125 patients.

scientific article

Heterogenous high-level HER-2 amplification in a small subset of colorectal cancers.

scientific article

High B7-H3 expression is linked to increased risk of prostate cancer progression

scientific article published on 10 August 2020

High BCAR1 expression is associated with early PSA recurrence in ERG negative prostate cancer

scientific article

High Ep-CAM expression is associated with poor prognosis in node-positive breast cancer

scientific article published on 01 August 2004

High c-MET expression is frequent but not associated with early PSA recurrence in prostate cancer

scientific article published on 25 October 2012

High concordance of findings obtained from transgluteal magnetic resonance imaging - and transrectal ultrasonography-guided biopsy as compared with prostatectomy specimens

scientific article

High epidermal growth factor receptor amplification rate but low mutation frequency in Middle East lung cancer population

scientific article published on 06 March 2006

High frequency and strong prognostic relevance of O6-methylguanine DNA methyltransferase silencing in diffuse large B-cell lymphomas from the Middle East

scientific article published on 01 June 2006

High homogeneity of MMR deficiency in ovarian cancer

scientific article published on 08 January 2020

High homogeneity of mismatch repair deficiency in advanced prostate cancer

scientific article published on 06 December 2019

High level PSMA expression is associated with early PSA recurrence in surgically treated prostate cancer

scientific article

High nuclear karyopherin α 2 expression is a strong and independent predictor of biochemical recurrence in prostate cancer patients treated by radical prostatectomy

scientific article published on 26 July 2013

High phospho-Stathmin(Serine38) expression identifies aggressive endometrial cancer and suggests an association with PI3K inhibition.

scientific article published on 28 March 2013

High throughput tissue microarray analysis of FHIT expression in diffuse large cell B-cell lymphoma from Saudi Arabia

scientific article published on 19 May 2006

High tissue density of FOXP3+ T cells is associated with clinical outcome in prostate cancer

scientific article published on 21 December 2012

High-Level Glyoxalase 1 (GLO1) expression is linked to poor prognosis in prostate cancer.

scientific article published on 19 September 2017

High-level expression of protein tyrosine phosphatase non-receptor 12 is a strong and independent predictor of poor prognosis in prostate cancer

scientific article published on 12 October 2019

High-level βIII-tubulin overexpression occurs in most head and neck cancers but is unrelated to clinical outcome

scientific article published on 22 June 2017

High-throughput tissue microarray analysis of 11q13 gene amplification (CCND1, FGF3, FGF4, EMS1) in urinary bladder cancer

article

High-throughput tissue microarray analysis of COX2 expression in urinary bladder cancer

scientific article published on 01 August 2005

High-throughput tissue microarray analysis ofCMYC amplificationin urinary bladder cancer

article

Homogeneous EGFR amplification defines a subset of aggressive Barrett's adenocarcinomas with poor prognosis.

scientific article

Immune Exclusion Is Frequent in Small-Cell Carcinoma of the Bladder

scientific article published on 02 May 2019

Immunoexpression analysis and prognostic value of BLCAP in breast cancer

scientific article

Immunohistochemical analysis of p16 expression, HPV infection and its prognostic utility in oral squamous cell carcinoma

scientific article published on 31 May 2013

Immunohistochemical analysis of tissue microarrays.

scientific article published on January 2010

Immunological microenvironment in prostate cancer: high mast cell densities are associated with favorable tumor characteristics and good prognosis

scientific article

Impaired expression of the cell cycle regulator BTG2 is common in clear cell renal cell carcinoma

scientific article published on March 2004

Impaired gastric acidification negatively affects calcium homeostasis and bone mass.

scientific article published in June 2009

Increased ERCC1 expression is linked to chromosomal aberrations and adverse tumor biology in prostate cancer

scientific article

Influence of slide aging on results of translational research studies using immunohistochemistry

scientific article

Integrated genomic analysis of the 8q24 amplification in endometrial cancers identifies ATAD2 as essential to MYC-dependent cancers

scientific article

Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer

scientific article

Intratumoral T but not B lymphocytes are related to clinical outcome in prostate cancer

scientific article published on 4 July 2012

KIT (CD117)-positive breast cancers are infrequent and lack KIT gene mutations

scientific article published in January 2004

Loss of cytoplasmic survivin expression is an independent predictor of poor prognosis in radically operated prostate cancer patients

scientific article published on 01 January 2020

Loss of pSer2448-mTOR expression is linked to adverse prognosis and tumor progression in ERG-fusion-positive cancers

scientific article published on 30 August 2012

Loss of protein expression and recurrent DNA hypermethylation of the GNG7 gene in squamous cell carcinoma of the head and neck.

scientific article published on 20 December 2011

Loss of reelin expression in breast cancer is epigenetically controlled and associated with poor prognosis

scientific article

Loss of the adhesion molecule CEACAM1 is associated with early biochemical recurrence in TMPRSS2:ERG fusion-positive prostate cancers

scientific article published on 09 March 2020

Low level HER2 overexpression is associated with rapid tumor cell proliferation and poor prognosis in prostate cancer

scientific article published on 23 February 2010

Lymphocyte activation antigen CD70 expressed by renal cell carcinoma is a potential therapeutic target for anti-CD70 antibody-drug conjugates

scientific article published in February 2006

MALDI imaging mass spectrometry reveals multiple clinically relevant masses in colorectal cancer using large-scale tissue microarrays

scientific article

MALDI imaging on large-scale tissue microarrays identifies molecular features associated with tumour phenotype in oesophageal cancer.

scientific article

MALDI mass spectrometric imaging based identification of clinically relevant signals in prostate cancer using large-scale tissue microarrays.

scientific article

MDM2 amplification is an independent prognostic feature of node-negative, estrogen receptor-positive early-stage breast cancer

scientific article published on 01 January 2010

MMR deficiency in urothelial carcinoma of the bladder presents with temporal and spatial homogeneity throughout the tumor mass

scientific article published on 14 February 2020

MMSET Is Highly Expressed and Associated with Aggressiveness in Neuroblastoma

scientific article published on 28 April 2011

Marked gene transcript level alterations occur early during radical prostatectomy

scientific article published on 09 April 2007

Marked heterogeneity of ERG expression in large primary prostate cancers

scientific article published on 17 August 2012

Microsatellite DNA alterations of gastrointestinal stromal tumors are predictive for outcome.

scientific article

Miliary never-smoking adenocarcinoma of the lung: strong association with epidermal growth factor receptor exon 19 deletion.

scientific article published in January 2011

Molecular cancer phenotype in normal prostate tissue

scientific article

No detection of XMRV in blood samples and tissue sections from prostate cancer patients in Northern Europe

scientific article

On the evidence for ESR1 amplification in breast cancer

article

Overexpression of carbonic anhydrase IX (CAIX) in vulvar cancer is associated with tumor progression and development of locoregional lymph node metastases

scientific article published in April 2010

Overexpression of carbonic anhydrase IX (CAIX) is an independent unfavorable prognostic marker in endometrioid ovarian cancer

scientific article published on 21 June 2011

Overexpression of cell division cycle 7 homolog is associated with gene amplification frequency in breast cancer.

scientific article

Overexpression of the chromatin remodeler death-domain-associated protein in prostate cancer is an independent predictor of early prostate-specific antigen recurrence

scientific article published on 2 May 2013

P53 immunohistochemical expression does not correlate with clinical features in 207 carcinomas of the oral cavity and in the head and neck region

scientific article published on 13 February 2013

PPFIA1 and CCND1 are frequently coamplified in breast cancer

scientific article published in January 2010

PSCA expression is associated with favorable tumor features and reduced PSA recurrence in operated prostate cancer.

scientific article

PTEN deletion is rare but often homogeneous in gastric cancer

scientific article published on 25 May 2012

Patterns of TIGIT Expression in Lymphatic Tissue, Inflammation, and Cancer

scientific article published on 10 January 2019

Patterns of chromosomal aberrations in urinary bladder tumours and adjacent urothelium

scientific article published on 01 September 2002

Predictive molecular pathology

scientific article published on 01 December 2002

Predominance of high-grade pathway in breast cancer development of Middle East women

scientific article published on 01 July 2005

Prevalence of CD8+ cytotoxic lymphocytes in human neoplasms

scientific article published on 05 March 2020

Prevalence of KIT expression in human tumors

scientific article published in November 2004

Prevalence of Syndecan-1 (CD138) Expression in Different Kinds of Human Tumors and Normal Tissues

scientific article published on 23 December 2019

Prognostic relevance of gene amplifications and coamplifications in breast cancer

scientific article published on 01 December 2004

Proteomic profiling of mammary carcinomas identifies C7orf24, a gamma-glutamyl cyclotransferase, as a potential cancer biomarker.

scientific article published in August 2010

Recipient block TMA technique

scientific article published on 01 January 2010

Reduced CD151 expression is related to advanced tumour stage in urothelial bladder cancer

scientific article published in August 2012

Reduced KLK2 expression is a strong and independent predictor of poor prognosis in ERG-negative prostate cancer

scientific article published on 06 July 2020

Role of TP53 mutations in vulvar carcinomas

scientific article published in September 2011

Role of cyclin D1 amplification and expression in vulvar carcinomas.

scientific article published on 9 March 2012

SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia

scientific article published on 3 October 2011

SNW1 is a prognostic biomarker in prostate cancer

scientific article published on 01 May 2019

SPINK1 expression is tightly linked to 6q15- and 5q21-deleted ERG-fusion negative prostate cancers but unrelated to PSA recurrence

scientific article published on 10 July 2013

Secreted Frizzled-Related Protein 4 (SFRP4) Is an Independent Prognostic Marker in Prostate Cancers Lacking TMPRSS2: ERG Fusions

scientific article published on 16 July 2020

Selective expression of a splice variant of decay-accelerating factor in c-erbB-2-positive mammary carcinoma cells showing increased transendothelial invasiveness.

scientific article published on April 2005

Sequence analysis and high-throughput immunohistochemical profiling of KIT (CD 117) expression in uveal melanoma using tissue microarrays

scientific article published on 26 September 2003

Serum midkine correlates with tumor progression and imatinib response in gastrointestinal stromal tumors

scientific article published on 30 June 2010

Strong expression of the neuronal transcription factor FOXP2 is linked to an increased risk of early PSA recurrence in ERG fusion-negative cancers

scientific article published on 4 April 2013

T-Cell Density at the Invasive Margin and Immune Phenotypes Predict Outcome in Vulvar Squamous Cell Cancer

scientific article published in 2022

TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling.

scientific article

Targeting activin receptor-like kinase 1 inhibits angiogenesis and tumorigenesis through a mechanism of action complementary to anti-VEGF therapies

scientific article published on 6 January 2011

The apoptosis linked gene ALG-2 is dysregulated in tumors of various origin and contributes to cancer cell viability.

scientific article

The expression and action of decay-accelerating factor (CD55) in human malignancies and cancer therapy

scientific article

The histone methyltransferase and putative oncoprotein MMSET is overexpressed in a large variety of human tumors

scientific article published on 8 March 2011

The independent prognostic impact of the GATA2 pioneering factor is restricted to ERG-negative prostate cancer

scientific article published on 01 July 2019

The relationship between annual hospital volume of trauma patients and in-hospital mortality in New York State

scientific article published in August 2011

The role of CXCR4 receptor expression in breast cancer: a large tissue microarray study.

scientific article

Tissue microarray (TMA) applications: implications for molecular medicine.

scientific article published on 21 October 2003

Tissue microarrays

scientific article published on 01 January 2004

Tissue microarrays

scientific article published on 01 January 2005

Tissue microarrays

scientific article published on 01 January 2010

Tissue microarrays

Tissue microarrays for comparing molecular features with proliferation activity in breast cancer

scientific article published on 01 May 2006

Tissue microarrays for high-throughput molecular pathology

scientific article published in May 2004

Tissue microarrays for miniaturized high-throughput molecular profiling of tumors.

scientific article

Up regulation of the Hippo signalling effector YAP1 is linked to early biochemical recurrence in prostate cancers

scientific article published on 02 June 2020

Upregulation of PTTG1 is associated with poor prognosis in prostate cancer

scientific article published on 20 April 2020

Upregulation of Phosphatase 1 Nuclear-Targeting Subunit (PNUTS) Is an Independent Predictor of Poor Prognosis in Prostate Cancer

scientific article published on 25 April 2020

Upregulation of the heterogeneous nuclear ribonucleoprotein hnRNPA1 is an independent predictor of early biochemical recurrence in TMPRSS2:ERG fusion-negative prostate cancers

scientific article published on 16 May 2020

Upregulation of the transcription factor TFAP2D is associated with aggressive tumor phenotype in prostate cancer lacking the TMPRSS2:ERG fusion

scientific article published on 06 March 2020

Y chromosome loss is a frequent early event in urothelial bladder cancer

scientific article published on 01 June 2010

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