List of works by Sarah Spain

A genome-wide analysis of putative functional and exonic variation associated with extremely high intelligence.

scientific article

A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21

article

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

article

A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk

article

A mitotic recombination map proximal to the APC locus on chromosome 5q and assessment of influences on colorectal cancer risk

scientific article published on 10 June 2009

An in-depth characterization of the major psoriasis susceptibility locus identifies candidate susceptibility alleles within an HLA-C enhancer element.

scientific article

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

scientific article

Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci

scientific journal article

Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk

scientific article published on 16 December 2007

Common variation at the adiponectin locus is not associated with colorectal cancer risk in the UK.

scientific article published on 5 March 2009

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

scientific article

Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis

scientific article

Deciphering the genetics of hereditary non-syndromic colorectal cancer

scientific article published on 16 July 2008

Disease severity and genetic pathways in attenuated familial adenomatous polyposis vary greatly but depend on the site of the germline mutation.

scientific article published on 4 February 2006

Do Genetic Susceptibility Variants Associate with Disease Severity in Early Active Rheumatoid Arthritis?

scientific article published on 15 May 2015

Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci

scientific article published on 5 May 2015

Erratum: A genome-wide analysis of putative functional and exonic variation associated with extremely high intelligence

article

Evidence for a colorectal cancer susceptibility locus on chromosome 3q21-q24 from a high-density SNP genome-wide linkage scan

article

Evidence of Linkage to Chromosome 9q22.33 in Colorectal Cancer Kindreds from the United Kingdom

article

Fine-mapping inflammatory bowel disease loci to single-variant resolution

scientific article

Genome-Wide Association Studies Suggest Limited Immune Gene Enrichment in Schizophrenia Compared to 5 Autoimmune Diseases

scientific article published on 30 May 2016

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas ⬇️

scientific article

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

scientific article

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.

scientific article

Investigating the genetic variation underlying episodicity in major depressive disorder: suggestive evidence for a bipolar contribution

scientific article published on 29 October 2013

Low penetrance breast cancer predisposition SNPs are site specific

article

Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

scientific article

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

scientific article

Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis.

scientific article

Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes

scientific article

Pregnancy does not influence colonic polyp multiplicity but may modulate upper gastrointestinal disease in patients with FAP.

scientific article published on 11 May 2007

Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13

scientific article published on 10 November 2011

Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer

article

Strategies for fine-mapping complex traits

scientific article published on 08 July 2015

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