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Authors whose works are in public domain in at least one jurisdiction

List of works by Chiara Castelli

Adaptive Immunity in Fibrosarcomatous Dermatofibrosarcoma Protuberans and Response to Imatinib Treatment.

scientific article published on 5 September 2016

Adaptive immune contexture at the tumour site and downmodulation of circulating myeloid-derived suppressor cells in the response of solitary fibrous tumour patients to anti-angiogenic therapy

scientific article

Alternative activation of human plasmacytoid DCs in vitro and in melanoma lesions: involvement of LAG-3.

scientific article

Antigen recognition by T cells: a strong sense of structure

scientific article published on 01 November 2001

Chemokine Receptor 7, A New Player in Regulating Apoptosis of CD8+ T Cells in Cancer Patients

scientific article published on 01 November 2005

Complex Immune Contextures Characterise Malignant Peritoneal Mesothelioma: Loss of Adaptive Immunological Signature in the More Aggressive Histological Types

scientific article published on 29 October 2018

Consensus nomenclature for CD8(+) T cell phenotypes in cancer

scientific article published on 25 February 2015

Cytotoxic T lymphocytes recognize tumor antigens of a murine colonic carcinoma by using different T-cell receptors

scientific article published on May 1994

Disulfide-linked surface molecules of monoclonal antigen-specific suppressor T cells: evidence for T cell receptor structures

scientific article published on 01 August 1985

Don't run before you can walk

scientific article published on 25 September 2012

Dose-finding/phase II trial: bevacizumab, immunotherapy, and chemotherapy (BIC) in metastatic renal cell cancer (mRCC). Antitumor effects and variations of circulating T regulatory cells (Treg).

scientific article

Effect of human natural killer and gammadelta T cells on the growth of human autologous melanoma xenografts in SCID mice

scientific article published in January 2004

Effects of cyclophosphamide and IL-2 on regulatory CD4+ T cell frequency and function in melanoma patients vaccinated with HLA-class I peptides: impact on the antigen-specific T cell response

scientific article published on 16 April 2013

Efficacy and Biological Activity of Imatinib in Metastatic Dermatofibrosarcoma Protuberans (DFSP).

scientific article

Erratum: Immune mechanisms in neoplasia

scholarly article by Chiara Castelli et al published 2005 in Drug discovery today. Disease mechanisms

Escape strategies and reasons for failure in the interaction between tumour cells and the immune system: how can we tilt the balance towards immune-mediated cancer control?

scientific article

Frequency of Circulating Tregs with Demethylated FOXP3 Intron 1 in Melanoma Patients Receiving Tumor Vaccines and Potentially Treg-Depleting Agents

scientific article published on 21 December 2010

Heat shock proteins and their use as anticancer vaccines.

scientific article

Heat shock proteins gp96 as immunogens in cancer patients

scientific article published on 01 May 2006

Heat shock proteins: biological functions and clinical application as personalized vaccines for human cancer.

scientific article published on 19 December 2003

Host immune response in renal cell cancer: Interleukin-4 (IL-4) and IL-10 mRNA are frequently detected in freshly collected tumor-infiltrating lymphocytes

article

Human allogeneic melanoma-reactive T-helper lymphocyte clones: functional analysis of lymphocyte-melanoma interactions

scientific article published on December 1991

Identification of a New Subset of Myeloid Suppressor Cells in Peripheral Blood of Melanoma Patients With Modulation by a Granulocyte-Macrophage Colony-Stimulation Factor–Based Antitumor Vaccine

scientific article published on 01 June 2007

Immune cells in the melanoma microenvironment hold information for prediction of the risk of recurrence and response to treatment

scientific article published on 10 June 2014

Immune mechanisms in neoplasia

scholarly article by Chiara Castelli et al published December 2004 in Drug discovery today. Disease mechanisms

Immune microenvironment profiling of gastrointestinal stromal tumors (GIST) shows gene expression patterns associated to immune checkpoint inhibitors response

scientific article published on 04 June 2019

Immune response markers in sentinel nodes may predict melanoma progression

scientific article

Immunity to cancer: attack and escape in T lymphocyte-tumor cell interaction

scientific article

Immunogenicity of the ALLAVGATK (gp10017 – 25) peptide in HLA-A3.1 melanoma patients ⬇️

scientific article published on April 1, 1998

Immunology and immunotherapy of colorectal cancer

scientific article

Immunomodulatory Factors Control the Fate of Melanoma Tumor Initiating Cells.

scientific article published on 14 June 2016

Immunotherapy of melanoma

scientific article published on 01 December 2003

Improved detection of melanoma antigen‐specific T cells expressing low or high levels of CD8 by HLA‐A2 tetramers presenting a Melan‐A/Mart‐1 peptide analogue ⬇️

scientific article published on January 1, 2002

In Reply

Induction of both CD8+ and CD4+ T-cell-mediated responses in colorectal cancer patients by colon antigen-1.

scientific article published on 30 October 2008

Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles.

scientific article

Inhibition of serine-peptidase activity enhances the generation of a survivin-derived HLA-A2-presented CTL epitope in colon-carcinoma cells.

scientific article

LAG-3 expression defines a subset of CD4(+)CD25(high)Foxp3(+) regulatory T cells that are expanded at tumor sites

scientific article

Limited induction of tumor cross-reactive T cells without a measurable clinical benefit in early melanoma patients vaccinated with human leukocyte antigen class I-modified peptides

scientific article published on 2 October 2012

Lymphocyte activation gene-3 (LAG-3, CD223) in plasmacytoid dendritic cells (pDCs): a molecular target for the restoration of active antitumor immunity

scientific article published on November 2014

Mass spectrometric identification of a naturally processed melanoma peptide recognized by CD8+ cytotoxic T lymphocytes

scientific article

Melan-A/MART-1 immunity in a EWS-ATF1 translocated clear cell sarcoma patient treated with sunitinib: a case report

scientific article

Melanoma immunology: past, present and future.

scientific article published on March 2007

Modified peptides in anti-cancer vaccines: are we eventually improving anti-tumour immunity?

scientific article published on 08 November 2008

Modulation of the myeloid compartment of the immune system by angiogenic- and kinase inhibitor-targeted anti-cancer therapies.

scientific article published on 04 July 2014

Monitoring the Frequency and Function of Regulatory T Cells and Summary of the Approaches Currently Used to Inhibit Regulatory T Cells in Cancer Patients

scientific article published on 01 January 2014

NKG2D engagement of colorectal cancer-specific T cells strengthens TCR-mediated antigen stimulation and elicits TCR independent anti-tumor activity

scientific article published on July 2003

NKG2D-mediated antitumor activity by tumor-infiltrating lymphocytes and antigen-specific T-cell clones isolated from melanoma patients

scientific article published on December 2007

Natural Killer andNK-LikeT-Cell Activation in Colorectal Carcinoma Patients Treated with Autologous Tumor-Derived Heat Shock Protein 96

scientific article published on 01 May 2005

P-glycoprotein gene amplification and expression in multidrug-resistant murine P388 and B16 cell lines

scientific article

PTPRK negatively regulates transcriptional activity of wild type and mutated oncogenic beta-catenin and affects membrane distribution of beta-catenin/E-cadherin complexes in cancer cells

scientific article

Peptide-specific CD8+ T-cell evolution in vivo: response to peptide vaccination with Melan-A/MART-1.

scientific article

Phenotypic characterization of human colorectal cancer stem cells

scientific article

Potent phagocytic activity discriminates metastatic and primary human malignant melanomas: a key role of ezrin

scientific article published on November 2003

Reconstitution of human telomerase reverse transcriptase expression rescues colorectal carcinoma cells from in vitro senescence: evidence against immortality as a constitutive trait of tumor cells

scientific article published in March 2005

Selective purging by human interleukin-2 activated lymphocytes of bone marrows contaminated with a lymphoma line or autologous leukaemic cells

scientific article published in June 1991

Soluble human LAG-3 molecule amplifies the in vitro generation of type 1 tumor-specific immunity

scientific article

Spheres of Influence in Cancer Stem Cell Biology

scientific article published on 21 October 2010

Structured myeloid cells and anti-angiogenic therapy in alveolar soft part sarcoma.

scientific article published on 27 September 2013

Sunitinib-induced morpho-functional changes and drug effectiveness in malignant solitary fibrous tumours

scientific article

T lymphocytes can mediate lysis of autologous melanoma cells by multiple mechanisms: evidence with a single T cell clone

scientific article published on January 1990

The T-cell response in patients with cancer

scientific article

Transcriptional profiling of melanoma sentinel nodes identify patients with poor outcome and reveal an association of CD30(+) T lymphocytes with progression

scientific article published on January 2014

Tumor necrosis factor-alpha induces coordinated changes in major histocompatibility class I presentation pathway, resulting in increased stability of class I complexes at the cell surface

scientific article published in August 2001

Universal and Stemness-Related Tumor Antigens: Potential Use in Cancer Immunotherapy

scientific article published on 01 October 2007

microRNA Expression in Sentinel Nodes from Progressing Melanoma Patients Identifies Networks Associated with Dysfunctional Immune Response

scientific article published on 14 December 2016

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