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List of works by Shin'ichi Oikawa

ACTH stimulation test and computed tomography are useful for differentiating the subtype of primary aldosteronism.

scientific article

ADIPOQ polymorphisms are associated with insulin resistance in Japanese women

scientific article published on 31 March 2015

Amadori-glycated phosphatidylethanolamine induces angiogenic differentiations in cultured human umbilical vein endothelial cells

scientific article (publication date: 4 December 2003)

Aminophospholipid glycation and its inhibitor screening system: a new role of pyridoxal 5'-phosphate as the inhibitor

scientific article published on 9 February 2006

Antiangiogenic and anticancer potential of unsaturated vitamin E (tocotrienol).

scientific article published on 13 December 2008

Aspirin for Stroke Prevention in Elderly Patients With Vascular Risk Factors: Japanese Primary Prevention Project

scientific article published on 10 May 2016

Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population

scientific article

Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography

scientific article published on 01 March 2012

Association of cholesteryl ester transfer protein activity and TaqIB polymorphism with lipoprotein variations in Japanese subjects

scientific article published in December 2003

Association of glycated albumin with the presence of carotid plaque in patients with type 2 diabetes.

scientific article

Association of serum apolipoprotein B48 level with the presence of carotid plaque in type 2 diabetes mellitus

scientific article published on 16 July 2008

Association of single-nucleotide polymorphisms in MTMR9 gene with obesity

scientific article published on 12 September 2007

Association of variations in the FTO, SCG3 and MTMR9 genes with metabolic syndrome in a Japanese population

article

Background to discuss guidelines for control of plasma HDL-cholesterol in Japan

scientific article published on 12 January 2012

CDH13 Polymorphisms are Associated with Adiponectin Levels and Metabolic Syndrome Traits Independently of Visceral Fat Mass.

scientific article published in October 2015

Characterization of pancreatic islets in two selectively bred mouse lines with different susceptibilities to high-fat diet-induced glucose intolerance.

scientific article published on 13 January 2014

Chylomicronemia caused by lipoprotein lipase gene mutation related to a hyper-response of insulin secretion to glucose.

scientific article

Clinical effects of rosuvastatin, a new HMG-CoA reductase inhibitor, in Japanese patients with primary hypercholesterolemia: an early phase II study

scientific article published in January 2002

Comparison of pituitary-adrenal responsiveness between insulin tolerance test and growth hormone-releasing peptide-2 test: a pilot study.

scientific article published on 5 January 2010

Comparison of three α-glucosidase inhibitors for glycemic control and bodyweight reduction in Japanese patients with obese type 2 diabetes

scientific article

Comparison of various lipid variables as predictors of coronary heart disease in Japanese men and women with type 2 diabetes: subanalysis of the Japan Diabetes Complications Study

scientific article published on 14 February 2012

Components of metabolic syndrome and their combinations as predictors of cardiovascular disease in Japanese patients with type 2 diabetes. Implications for improved definition. Analysis from Japan Diabetes Complications Study (JDCS).

scientific article

Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area

article

Diabetes mellitus with dyslipidemia

scientific article published in April 2016

Diagnosis and Management of Type I and Type V Hyperlipoproteinemia

scientific article published on 01 December 2011

Dietary isohumulones, the bitter components of beer, raise plasma HDL-cholesterol levels and reduce liver cholesterol and triacylglycerol contents similar to PPARalpha activations in C57BL/6 mice

scientific article published in April 2005

Different pathogenesis of glucose intolerance in two subtypes of primary aldosteronism: aldosterone-producing adenoma and idiopathic hyperaldosteronism

scientific article published on 29 May 2020

Distinct effects of pravastatin, atorvastatin, and simvastatin on insulin secretion from a beta-cell line, MIN6 cells

scientific article published on December 2006

Effect of HMG-CoA reductase inhibitor on plasma cholesteryl ester transfer protein activity in primary hypercholesterolemia: comparison among CETP/TaqIB genotype subgroups

scientific article published in January 2002

Effect of impaired glucose tolerance on atherosclerotic lesion formation: an evaluation in selectively bred mice with different susceptibilities to glucose intolerance.

scientific article published on 17 October 2013

Effect of mulberry leaf extract with enriched 1-deoxynojirimycin content on postprandial glycemic control in subjects with impaired glucose metabolism

scientific article

Effects of EPA on coronary artery disease in hypercholesterolemic patients with multiple risk factors: sub-analysis of primary prevention cases from the Japan EPA Lipid Intervention Study (JELIS).

scientific article published on 19 June 2008

Effects of daily aspirin on cancer incidence and mortality in the elderly Japanese

scientific article published on 15 April 2018

Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis

scientific article

Effects of hypertension and type 2 diabetes mellitus on the risk of total cardiovascular events in Japanese patients with hypercholesterolemia: implications from the Japan Lipid Intervention Trial (J-LIT).

scientific article published on February 2007

Effects of insulin, leptin, and glucagon on ghrelin secretion from isolated perfused rat stomach

scientific article

Effects of mulberry leaf extract rich in 1-deoxynojirimycin on blood lipid profiles in humans

scientific article

Efficacy and Safety of Long-term Coadministration of Fenofibrate and Ezetimibe in Patients with Combined Hyperlipidemia: Results of the EFECTL Study

scientific article published on 08 July 2016

Elevation of HDL-C in response to statin treatment is involved in the regression of carotid atherosclerosis

scientific article published on 13 June 2014

Etiological significance of apolipoprotein E mutations in lipoprotein glomerulopathy

scientific article

Evaluation of right adrenal vein cannulation by computed tomography angiography in 140 consecutive patients undergoing adrenal venous sampling

scientific article published on 08 March 2014

Ezetimibe Lipid-Lowering Trial on Prevention of Atherosclerotic Cardiovascular Disease in 75 or Older (EWTOPIA 75): A Randomized, Controlled Trial

scientific article published on 22 August 2019

Familial hypercholesterolemia.

scientific article published on 10 December 2013

Fat intake and the development of type 2 diabetes

scientific article

Food-grade mulberry powder enriched with 1-deoxynojirimycin suppresses the elevation of postprandial blood glucose in humans

scientific article published on 08 June 2007

FoxO1 breaks diabetic heart

scientific article published on 28 November 2012

Frequency of Achilles Tendon Xanthoma in Patients with Acute Coronary Syndrome.

scientific article published on 2 March 2017

Fructose ingestion enhances atherosclerosis and deposition of advanced glycated end-products in cholesterol-fed rabbits

scientific article

Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity

scientific article

Gender difference in coronary events in relation to risk factors in Japanese hypercholesterolemic patients treated with low-dose simvastatin

scientific article published on 01 July 2006

Genetic suppression of ghrelin receptors activates brown adipocyte function and decreases fat storage in rats

scientific article

Genetic variations in the CYP17A1 and NT5C2 genes are associated with a reduction in visceral and subcutaneous fat areas in Japanese women.

scientific article

Ghrelin stimulates GH but not food intake in arcuate nucleus ablated rats

scientific article published in September 2002

Growth Hormone-Releasing Hormone (GHRH) Neurons in the Arcuate Nucleus (Arc) of the Hypothalamus Are Decreased in Transgenic Rats Whose Expression of Ghrelin Receptor Is Attenuated: Evidence that Ghrelin Receptor Is Involved in the Up-Regulation of G

article

Guidelines for the Management of Familial Hypercholesterolemia ⬇️

scientific article published on October 25, 2012

Guidelines for the management of atherosclerotic diseases in diabetes mellitus

scientific article (publication date: November 2006)

High purity tocotrienols attenuate atherosclerotic lesion formation in apoE-KO mice.

scientific article

Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding, and adiposity

scientific article

Hypothalamic neuropeptide Y/Y1 receptor pathway activated by a reduction in circulating leptin, but not by an increase in circulating ghrelin, contributes to hyperphagia associated with triiodothyronine-induced thyrotoxicosis

scientific article published in December 2003

INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.

scientific article published on 10 July 2008

Identical germline mutations in the TMEM127 gene in two unrelated Japanese patients with bilateral pheochromocytoma ⬇️

scientific article published on 01 November 2012

Impact of lipoprotein glomerulopathy on the relationship between lipids and renal diseases

scientific article

In vivo angiogenesis is suppressed by unsaturated vitamin E, tocotrienol

scientific article published on August 2007

Increase of serum phosphatidylcholine hydroperoxide dependent on glycemic control in type 2 diabetic patients

scientific article published in April 2002

Incremental effects of eicosapentaenoic acid on cardiovascular events in statin-treated patients with coronary artery disease

scientific article published on 8 May 2009

Influence of blood pressure on the effects of low-dose asprin in elderly patients with multiple atherosclerotic risks

scientific article published on 01 June 2019

Insulin and heparin challenge tests are useful for choosing an optimal insulin regimen in a case of subcutaneous insulin resistance

scientific article published on 08 April 2020

Insulin-like growth factor-I down-regulates ghrelin receptor (growth hormone secretagogue receptor) expression in the rat pituitary

scientific article

International clinical harmonization of glycated hemoglobin in Japan: From Japan Diabetes Society to National Glycohemoglobin Standardization Program values

scientific article

Investigation of Obstructive Sleep Apnea Using Portable Monitors and Health Check Data in Japanese Drivers

article

Involvement of Rac GTPase activation in phosphatidylcholine hydroperoxide-induced THP-1 cell adhesion to ICAM-1.

scientific article published on 18 February 2011

Ion-trap tandem mass spectrometric analysis of Amadori-glycated phosphatidylethanolamine in human plasma with or without diabetes

scientific article published on 08 September 2005

Ion-trap tandem mass spectrometric analysis of squalene monohydroperoxide isomers in sunlight-exposed human skin

scientific article published on 11 September 2007

Is hyperfattyacidemia related to the occurrence of diabetes?

scientific article

Isohumulones modulate blood lipid status through the activation of PPAR alpha

scientific article published in September 2005

Isohumulones, bitter acids derived from hops, activate both peroxisome proliferator-activated receptor alpha and gamma and reduce insulin resistance

scientific article

LC-MS/MS analysis of carboxymethylated and carboxyethylated phosphatidylethanolamines in human erythrocytes and blood plasma.

scientific article

Large scale cohort study of the relationship between serum cholesterol concentration and coronary events with low-dose simvastatin therapy in Japanese patients with hypercholesterolemia

scientific article

Large scale cohort study of the relationship between serum cholesterol concentration and coronary events with low-dose simvastatin therapy in Japanese patients with hypercholesterolemia and coronary heart disease: secondary prevention cohort study o

scientific article

Large-scale cohort study on the relationship between serum lipid concentrations and risk of cerebrovascular disease under low-dose simvastatin in Japanese patients with hypercholesterolemia: sub-analysis of the Japan Lipid Intervention Trial (J-LIT)

scientific article published on September 2005

Leptin production capacity determines food intake and susceptibility to obesity-induced diabetes in Oikawa-Nagao Diabetes-Prone and Diabetes-Resistant mice

scientific article published on 19 June 2020

Liquid chromatography-tandem mass spectrometry determination of human plasma 1-palmitoyl-2-hydroperoxyoctadecadienoyl-phosphatidylcholine isomers via promotion of sodium adduct formation

scientific article published on 11 November 2014

Liver Transplantation for Homozygous Familial Hypercholesterolemia

Long-term outcome after living donor liver transplantation for two cases of homozygous familial hypercholesterolemia from a heterozygous donor

scientific article published on 01 April 2007

Low-Dose Aspirin for Primary Prevention of Cardiovascular Events in Elderly Japanese Patients with Atherosclerotic Risk Factors: Subanalysis of a Randomized Clinical Trial (JPPP-70)

scientific article published on 01 June 2019

Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial

scientific article published on December 2014

Management of Type IIb Dyslipidemia

scientific article published on 03 December 2011

Meaning of dyslipidemia management in diabetes

scientific article published on 01 July 2012

Metformin Attenuates Early-Stage Atherosclerosis in Mildly Hyperglycemic Oikawa-Nagao Mice

scientific article published on 11 April 2019

Multicenter study to determine the diagnosis criteria of heterozygous familial hypercholesterolemia in Japan

scientific article published on 25 October 2012

NUDT3 rs206936 is associated with body mass index in obese Japanese women

scientific article published on 25 May 2013

Obesity as a risk factor for coronary events in Japanese patients with hypercholesterolemia on low-dose simvastatin therapy

scientific article published on 16 January 2010

Occurrence of orally administered mulberry 1-deoxynojirimycin in rat plasma

scientific article published on 4 October 2007

Oxidized but not acetylated low-density lipoprotein reduces preproinsulin mRNA expression and secretion of insulin from HIT-T15 cells.

scientific article published on February 2005

Phosphatidylcholine hydroperoxide-induced THP-1 cell adhesion to intracellular adhesion molecule-1.

scientific article

Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population.

scientific article published on 12 August 2010

Polymorphisms in four genes related to triglyceride and HDL-cholesterol levels in the general Japanese population in 2000.

scientific article

Polymorphisms of apolipoprotein e and methylenetetrahydrofolate reductase in the Japanese population

scientific article published on 14 August 2007

Postprandial Increase in Energy Expenditure Correlates with Body Weight Reduction in Patients with Type 2 Diabetes Receiving Diet Therapy

scientific article

Potential Protection Against Type 2 Diabetes in Obesity Through Lower CD36 Expression and Improved Exocytosis in β-Cells

scientific article published on 20 March 2020

Practical dietary calorie management, body weight control and energy expenditure of diabetic patients in short-term hospitalization.

scientific article published on 18 March 2010

Preparation of pure lipid hydroperoxides.

scientific article published on 18 July 2008

Prevalence of metabolic syndrome in the general Japanese population in 2000

scientific article published on 01 August 2006

Preventive effects of eicosapentaenoic acid on coronary artery disease in patients with peripheral artery disease

scientific article published on 18 May 2010

Primary cardiovascular events and serum lipid levels in elderly Japanese with hypercholesterolemia undergoing 6-year simvastatin treatment: a subanalysis of the Japan lipid intervention trial

scientific article published in December 2004

Proposed guidelines for hypertriglyceridemia in Japan with non-HDL cholesterol as the second target

scientific article published in June 2008

Rationale, design, and baseline data of the Japanese Primary Prevention Project (JPPP)-a randomized, open-label, controlled trial of aspirin versus no aspirin in patients with multiple risk factors for vascular events

scientific article

Reduction in the recurrence of stroke by eicosapentaenoic acid for hypercholesterolemic patients: subanalysis of the JELIS trial

scientific article published in May 2008

Relationship between Coronary Artery Disease and Non-HDL-C, and Effect of Highly Purified EPA on the Risk of Coronary Artery Disease in Hypercholesterolemic Patients Treated with Statins: Sub-Analysis of the Japan EPA Lipid Intervention Study (JELIS) ⬇️

scientific article published on December 17, 2011

Relationship between coronary events and serum cholesterol during 10 years of low-dose simvastatin therapy: long-term efficacy and safety in Japanese patients with hypercholesterolemia in the Japan Lipid Intervention Trial (J-LIT) Extension 10 Study

scientific article published in August 2008

Relationships between plasma fatty acid composition and coronary artery disease ⬇️

scientific article published on November 17, 2010

Repetitive Glucose Spikes Accelerate Atherosclerotic Lesion Formation in C57BL/6 Mice.

scientific article published on 27 August 2015

Replication study of 15 recently published Loci for body fat distribution in the Japanese population.

scientific article published on 7 December 2012

Report of the Japan Atherosclerosis Society (JAS) Guideline for Diagnosis and Treatment of Hyperlipidemia in Japanese adults

scientific article published on January 2002

Risk of coronary events in Japanese patients with both hypercholesterolemia and type 2 diabetes mellitus on low-dose simvastatin therapy: implication from Japan Lipid Intervention Trial (J-LIT).

scientific article published on 12 June 2006

Role of ghrelin in streptozotocin-induced diabetic hyperphagia

scientific article

Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick-Kaufman syndrome gene variants are associated with metabolic syndrome.

scientific article published on 27 February 2009

Selective breeding of mice for different susceptibilities to high fat diet-induced glucose intolerance: Development of two novel mouse lines, Selectively bred Diet-induced Glucose intolerance-Prone and -Resistant

scientific article

Selectively Bred Diabetes Models: GK Rats, NSY Mice, and ON Mice

scientific article published on 01 January 2020

Serum level of triglycerides is a potent risk factor comparable to LDL cholesterol for coronary heart disease in Japanese patients with type 2 diabetes: subanalysis of the Japan Diabetes Complications Study (JDCS) ⬇️

scientific article published on August 24, 2011

Serum lipid survey and its recent trend in the general Japanese population in 2000.

scientific article

Severe Insulin-resistant Diabetes due to Insulin Antibodies Associated with Eosinophilia.

scientific article published on 15 September 2015

Severity and multiplicity of microvascular complications are associated with QT interval prolongation in patients with type 2 diabetes.

scientific article published on 2 November 2017

Sitagliptin improves plasma apolipoprotein profile in type 2 diabetes: A randomized clinical trial of sitagliptin effect on lipid and glucose metabolism (SLIM) study

scientific article published on 17 March 2020

Suppressive effect of EPA on the incidence of coronary events in hypercholesterolemia with impaired glucose metabolism: Sub-analysis of the Japan EPA Lipid Intervention Study (JELIS).

scientific article published on 5 April 2009

Sustained reduction of serum cholesterol in low-dose 6-year simvastatin treatment with minimum side effects in 51,321 Japanese hypercholesterolemic patients

scientific article published in April 2003

Telomere shortening of peripheral blood mononuclear cells in coronary disease patients with metabolic disorders

scientific article published on 01 February 2003

The Change in Low-Density Lipoprotein Cholesterol Concentration is Positively Related to Plasma Docosahexaenoic Acid but not Eicosapentaenoic Acid ⬇️

scientific article published on May 26, 2012

The effect of agouti-related protein on growth hormone secretion in adult male rats

scientific article published on 01 February 2005

The effects of partial use of formula diet on weight reduction and metabolic variables in obese type 2 diabetic patients--multicenter trial

scientific article published in January 2013

The estrogen receptor (ER) alpha, but not ER beta, gene is expressed in hypothalamic growth hormone-releasing hormone neurons of the adult female rat.

scientific article published in May 2005

The new worldwide definition of metabolic syndrome is not a better diagnostic predictor of cardiovascular disease in Japanese diabetic patients than the existing definitions: additional analysis from the Japan Diabetes Complications Study

scientific article published in January 2006

The recovery of dysfunctional lipoprotein lipase (Asp204-Glu) activity by modification of substrate

scientific article published in November 2005

The risk of cardiovascular events in Japanese hypertensive patients with hypercholesterolemia: sub-analysis of the Japan Lipid Intervention Trial (J-LIT) Study, a large-scale observational cohort study

scientific article published in November 2005

The role of pituitary ghrelin in growth hormone (GH) secretion: GH-releasing hormone-dependent regulation of pituitary ghrelin gene expression and peptide content

scientific article

Therapeutic points and meaning of dyslipidemia in diabetic patients

scientific article published in May 2010

Transgenerational changes of metabolic phenotypes in two selectively bred mouse colonies for different susceptibilities to diet-induced glucose intolerance.

scientific article published on 21 January 2015

Triiodothyronine (T3) stimulates food intake via enhanced hypothalamic AMP-activated kinase activity

scientific article published on 29 July 2008

Tumor anti-angiogenic effect and mechanism of action of delta-tocotrienol.

scientific article

Validation of an ion trap tandem mass spectrometric analysis of mulberry 1-deoxynojirimycin in human plasma: application to pharmacokinetic studies

scientific article published on 7 August 2008

Variations in the FTO gene are associated with severe obesity in the Japanese

scientific article published on April 2008

Waist circumference as a cardiovascular and metabolic risk in Japanese patients with type 2 diabetes

scientific article published on 20 November 2008

[Diabetic macroangiopathy--therapy and prevention]

scientific article published on 01 September 2002

[Dyslipidemia in diabetes mellitus: diagnosis and treatment]

[Hypolipidemia in Japan]

scientific article published on 01 July 2007

[Intervention for hypertriglyceridemia]

scientific article published on 01 July 2007

[Meaning and policy of treatment for dyslipidemia in diabetic microangiopathy]

scientific article published on 01 November 2010

[Metabolic syndrome and aging]

scientific article published on 01 March 2007

[Obesity: Progress in diagnosis and treatment; Topics, III. Obesity and its complications; 3. Obesity and dyslipidemia]

scientific article published on 01 April 2011

delta-Tocotrienol suppresses VEGF induced angiogenesis whereas alpha-tocopherol does not.

scientific article

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