List of works by Kristina Lorenz

"Photo-Rimonabant": Synthesis and Biological Evaluation of Novel Photoswitchable Molecules Derived from Rimonabant Lead to a Highly Selective and Nanomolar "<i>Cis</i>-On" CB<sub>1</sub>R Antagonist

scientific article published on 15 April 2021

A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy

scientific article

Age-dependent Increase in JNK2 Activity: Does This Help to Understand CaMKII-mediated Atrial Arrhythmogenesis in Human Atrial Fibrillation?

scientific article published on 8 February 2018

Analysis of fibrosis in control or pressure overloaded rat hearts after mechanical unloading by heterotopic heart transplantation

scientific article published on 05 April 2019

Analyzing ERK 1/2 signalling and targets

scientific article published on 15 June 2016

Association between Comorbidities and Progression of Transvalvular Pressure Gradients in Patients with Moderate and Severe Aortic Valve Stenosis

scientific article published on 11 November 2018

Beta-arrestin binding to the beta2-adrenergic receptor requires both receptor phosphorylation and receptor activation.

scientific article

Blocking of α4 integrin does not protect from acute ischemic stroke in mice.

scientific article published on 17 April 2014

CD28 superagonist-mediated boost of regulatory T cells increases thrombo-inflammation and ischemic neurodegeneration during the acute phase of experimental stroke.

scientific article published on 15 October 2014

Cardiac RKIP induces a beneficial β-adrenoceptor-dependent positive inotropy.

scientific article published on 19 October 2015

Cardiac amyloidosis mimicking severe aortic valve stenosis - a case report demonstrating diagnostic pitfalls and role of dobutamine stress echocardiography

scientific article

Cardiac hypertrophy: targeting Raf/MEK/ERK1/2-signaling.

scientific article published on 08 August 2009

Coagulation factor XII induces pro-inflammatory cytokine responses in macrophages and promotes atherosclerosis in mice

article

Conformational cross-talk between alpha2A-adrenergic and mu-opioid receptors controls cell signaling

scientific article published on 13 January 2008

Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome.

scientific article published on 5 December 2017

Crosstalk between sentinel and helper macrophages permits neutrophil migration into infected uroepithelium

scientific article

Differences in natural history of low- and high-gradient aortic stenosis from nonsevere to severe stage of the disease.

scientific article published on 26 August 2015

Ectopic expression of S28A-mutated Histone H3 modulates longevity, stress resistance and cardiac function in Drosophila.

scientific article published on 13 February 2018

Efficacy and Safety of Platelet Glycoprotein Receptor Blockade in Aged and Comorbid Mice With Acute Experimental Stroke.

scientific article published on 20 October 2015

Erratum: Cardiac RKIP induces a beneficial β-adrenoceptor-dependent positive inotropy.

scientific article published in February 2016

Eukaryotic elongation factor 2 is a prognostic marker and its kinase a potential therapeutic target in HCC.

scientific article published on 02 January 2017

FTY720 ameliorates acute ischemic stroke in mice by reducing thrombo-inflammation but not by direct neuroprotection

scientific article published on 12 September 2013

Harnessing RKIP to Combat Heart Disease and Cancer

scientific article published in 2022

Heart failure-specific changes in protein kinase signalling.

scientific article published on 08 February 2014

How to Steer and Control ERK and the ERK Signaling Cascade Exemplified by Looking at Cardiac Insufficiency. ⬇️

scientific article published on 2 May 2019

Inhibition of cardiac CaMKII to cure heart failure: step by step towards translation?

scientific article published on 28 September 2016

Interference with ERK-dimerization at the nucleocytosolic interface targets pathological ERK1/2 signaling without cardiotoxic side-effects

scientific article published on 07 April 2020

Loss of Survivin influences liver regeneration and is associated with impaired Aurora B function.

scientific article

Multi-OMICS: a critical technical perspective on integrative lipidomics approaches.

scientific article published on 10 February 2017

Myocardial Fibrosis Predicts 10-Year Survival in Patients Undergoing Aortic Valve Replacement

scientific article published on 01 August 2018

Oral Chaperone Therapy Migalastat for Treating Fabry Disease: Enzymatic Response and Serum Biomarker Changes After 1 Year

scientific article published on 13 January 2019

Oxidation of cardiac myofilament proteins: Priming for dysfunction?

scientific article published on 23 August 2018

PKA catalytic subunit mutations in adrenocortical Cushing's adenoma impair association with the regulatory subunit.

scientific article

Partial agonist activity of bucindolol is dependent on the activation state of the human beta1-adrenergic receptor

scientific article published on 7 July 2003

Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction.

scientific article published on 31 October 2016

Phosphorylation or Mutation of the ERK2 Activation Loop Alters Oligonucleotide Binding.

scientific article published on 07 March 2016

Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2

scientific journal article

RKIP: a governor of intracellular signaling

scientific journal article

Raf kinase inhibitor protein: lessons of a better way for β-adrenergic receptor activation in the heart.

scientific article

Real-time Triggered RAdial Single-Shot Inversion recovery for arrhythmia-insensitive myocardial T1 mapping: motion phantom validation and in vivo comparison

scientific article published on 12 November 2018

Sex-difference in expression and function of beta-adrenoceptors in macrovessels: role of the endothelium.

scientific article

The A2B adenosine receptor in MDA-MB-231 breast cancer cells diminishes ERK1/2 phosphorylation by activation of MAPK-phosphatase-1

scientific article published in PLoS ONE

The N-termini of GRK2 and GRK3 simulate the stimulating effects of RKIP on β-adrenoceptors

scientific article published on 08 October 2019

The amino-terminal domain of G-protein-coupled receptor kinase 2 is a regulatory Gbeta gamma binding site

scientific article published on 16 December 2002

The potential of remdesivir to affect function, metabolism and proliferation of cardiac and kidney cells in vitro

scientific article published in 2022

The transcriptional repressor Nab1 is a specific regulator of pathological cardiac hypertrophy

scientific article published on 17 July 2005

The β2 agonist terbutaline specifically decreases pulmonary arterial pressure under normoxia and hypoxia via α adrenoceptor antagonism.

scientific article published on 2 January 2018

beta-Arrestin-2 interaction and internalization of the human P2Y1 receptor are dependent on C-terminal phosphorylation sites.

scientific article

α-Galactosidase A Genotype N215S Induces a Specific Cardiac Variant of Fabry Disease

scientific article published in October 2017

β 1 Adrenoceptor antagonistic effects of the supposedly selective β 2 adrenoceptor antagonist ICI 118,551 on the positive inotropic effect of adrenaline in murine hearts.

scientific article published on 31 July 2015

β-Adrenoceptor-Mediated Relaxation of Carbachol-Pre-Contracted Mouse Detrusor

scientific article published on 30 January 2015

β-Arrestin biosensors reveal a rapid, receptor-dependent activation/deactivation cycle

scientific article published on 23 March 2016

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