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List of works by Helen S Toogood

A site-saturated mutagenesis study of pentaerythritol tetranitrate reductase reveals that residues 181 and 184 influence ligand binding, stereochemistry and reactivity

scientific article

A surprising observation that oxygen can affect the product enantiopurity of an enzyme-catalysed reaction

article

A thermostable L-aminoacylase from Thermococcus litoralis: cloning, overexpression, characterization, and applications in biotransformations

scientific article published in April 2002

Asymmetric Reduction of Activated Alkenes by Pentaerythritol Tetranitrate Reductase: Specificity and Control of Stereochemical Outcome by Reaction Optimisation.

scientific article published on November 2009

Biocatalysis with thermostable enzymes: structure and properties of a thermophilic 'ene'-reductase related to old yellow enzyme

scientific article

C3 and C6 Modification-Specific OYE Biotransformations of Synthetic Carvones and Sequential BVMO Chemoenzymatic Synthesis of Chiral Caprolactones

scientific article published on 15 January 2019

Chemoenzymatic Synthesis of the Intermediates in the Peppermint Monoterpenoid Biosynthetic Pathway

scientific article published on 06 July 2018

Co‐production of biofuel, bioplastics and biochemicals during extended fermentation of <i>Halomonas bluephagenesis</i>

scientific article published in 2022

Cysteine activation is an inherent in vitro property of prolyl-tRNA synthetases

scientific article

Dynamics driving function: new insights from electron transferring flavoproteins and partner complexes.

scientific article published on 17 October 2007

ELDOR Spectroscopy Reveals that Energy Landscapes in Human Methionine Synthase Reductase are Extensively Remodelled Following Ligand and Partner Protein Binding

scientific article published on 25 February 2011

Evolutionary divergence of the archaeal aspartyl-tRNA synthetases into discriminating and nondiscriminating forms

scientific article published on 30 July 2002

Expanding tRNA recognition of a tRNA synthetase by a single amino acid change

scholarly article

Extensive domain motion and electron transfer in the human electron transferring flavoprotein.medium chain Acyl-CoA dehydrogenase complex.

scientific article

Focused directed evolution of pentaerythritol tetranitrate reductase by using automated anaerobic kinetic screening of site-saturated libraries

scientific article

Machine Learning of Designed Translational Control Allows Predictive Pathway Optimization in Escherichia coli

scientific article published on 07 January 2019

Novel haem co-ordination variants of flavocytochrome P450BM3

scientific article

Pinpointing a Mechanistic Switch Between Ketoreduction and "Ene" Reduction in Short-Chain Dehydrogenases/Reductases

scientific article published on 13 July 2016

Pinpointing a Mechanistic Switch Between Ketoreduction and "Ene" Reduction in Short-Chain Dehydrogenases/Reductases.

scientific article

Reduction of aliphatic nitroesters and N-nitramines by Enterobacter cloacae PB2 pentaerythritol tetranitrate reductase: quantitative structure-activity relationships.

scientific article published on 5 November 2008

Retooling microorganisms for the fermentative production of alcohols

scientific article published on 5 September 2017

Stabilization of non-productive conformations underpins rapid electron transfer to electron-transferring flavoprotein.

scientific article

Structural and spectroscopic characterization of P450 BM3 mutants with unprecedented P450 heme iron ligand sets. New heme ligation states influence conformational equilibria in P450 BM3.

scientific article published on 31 October 2006

Structure-Based Insight into the Asymmetric Bioreduction of the C=C Double Bond of alpha,beta-Unsaturated Nitroalkenes by Pentaerythritol Tetranitrate Reductase

scientific article published on November 2008