List of works - Anna Fryszkowska

A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins

scientific article published in 2022

A short, chemoenzymatic route to chiral beta-aryl-gamma-amino acids using reductases from anaerobic bacteria

scientific article published on 10 November 2009

A site-saturated mutagenesis study of pentaerythritol tetranitrate reductase reveals that residues 181 and 184 influence ligand binding, stereochemistry and reactivity

scientific article

A surprising observation that oxygen can affect the product enantiopurity of an enzyme-catalysed reaction

article

Activation of chlorine and fluorine by a phenylazo group towards nucleophilic aromatic substitution. Regioselective preparation of polysubstituted anilines

Active site modifications in pentaerythritol tetranitrate reductase can lead to improved product enantiopurity, decreased by-product formation and altered stereochemical outcome in reactions with α,β-unsaturated nitroolefins

article

Asymmetric Reduction of Activated Alkenes by Pentaerythritol Tetranitrate Reductase: Specificity and Control of Stereochemical Outcome by Reaction Optimisation.

scientific article published on November 2009

Biocatalysis in drug discovery and development

scientific article published on 10 March 2020

Biocatalysis with thermostable enzymes: structure and properties of a thermophilic 'ene'-reductase related to old yellow enzyme

scientific article

Circular dichroism studies on absolute configuration assignment of peptidomimetics with a terminal chiral 3-arylpropionic acid unit

article

Combination of Enzymic Procedures with Multicomponent Condensations

Combination of enzymatic procedures with multicomponent condensations

Design of an in vitro biocatalytic cascade for the manufacture of islatravir

scientific article published on 01 December 2019

Development of a Chemoenzymatic Process for Dehydroepiandrosterone Acetate Synthesis

article

Enzymatic desymmetrization of 3-arylglutaric acid anhydrides

Focused directed evolution of pentaerythritol tetranitrate reductase by using automated anaerobic kinetic screening of site-saturated libraries

scientific article

Highly enantioselective reduction of beta,beta-disubstituted aromatic nitroalkenes catalyzed by Clostridium sporogenes

scientific article

Inside Cover: Focused Directed Evolution of Pentaerythritol Tetranitrate Reductase by Using Automated Anaerobic Kinetic Screening of Site-Saturated Libraries (ChemBioChem 17/2010)

scientific article published in 2010

One-pot enzymatic desymmetrization and Ugi MCR

Structural insights into the ene-reductase synthesis of profens.

scientific article published on 09 May 2017

Structure-Based Insight into the Asymmetric Bioreduction of the C=C Double Bond of alpha,beta-Unsaturated Nitroalkenes by Pentaerythritol Tetranitrate Reductase

scientific article published on November 2008

Studies on enzymatic synthesis of chiral non-racemic 3-arylglutaric acid monoesters

article published in 2006

Studies towards the synthesis of bicyclomycin precursors: Synthesis ofN,N′-disubstituted 2,5-diketopiperazines in solution and on solid phase

Synthesis of Islatravir Enabled by a Catalytic, Enantioselective Alkynylation of a Ketone

scientific article published on 09 June 2020

Synthesis of Liquid Crystalline 4H-Benzo[1,2,4]thiadiazines and Generation of Persistent Radicals

scientific article published on 04 April 2007

List of works by Anna Fryszkowska

A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins

A short, chemoenzymatic route to chiral beta-aryl-gamma-amino acids using reductases from anaerobic bacteria

A site-saturated mutagenesis study of pentaerythritol tetranitrate reductase reveals that residues 181 and 184 influence ligand binding, stereochemistry and reactivity

A surprising observation that oxygen can affect the product enantiopurity of an enzyme-catalysed reaction

Activation of chlorine and fluorine by a phenylazo group towards nucleophilic aromatic substitution. Regioselective preparation of polysubstituted anilines

Active site modifications in pentaerythritol tetranitrate reductase can lead to improved product enantiopurity, decreased by-product formation and altered stereochemical outcome in reactions with α,β-unsaturated nitroolefins

Asymmetric Reduction of Activated Alkenes by Pentaerythritol Tetranitrate Reductase: Specificity and Control of Stereochemical Outcome by Reaction Optimisation.

Biocatalysis in drug discovery and development

Biocatalysis with thermostable enzymes: structure and properties of a thermophilic 'ene'-reductase related to old yellow enzyme

Circular dichroism studies on absolute configuration assignment of peptidomimetics with a terminal chiral 3-arylpropionic acid unit

Combination of Enzymic Procedures with Multicomponent Condensations

Combination of enzymatic procedures with multicomponent condensations

Design of an in vitro biocatalytic cascade for the manufacture of islatravir

Development of a Chemoenzymatic Process for Dehydroepiandrosterone Acetate Synthesis

Enzymatic desymmetrization of 3-arylglutaric acid anhydrides

Focused directed evolution of pentaerythritol tetranitrate reductase by using automated anaerobic kinetic screening of site-saturated libraries

Highly enantioselective reduction of beta,beta-disubstituted aromatic nitroalkenes catalyzed by Clostridium sporogenes

Inside Cover: Focused Directed Evolution of Pentaerythritol Tetranitrate Reductase by Using Automated Anaerobic Kinetic Screening of Site-Saturated Libraries (ChemBioChem 17/2010)

One-pot enzymatic desymmetrization and Ugi MCR

Structural insights into the ene-reductase synthesis of profens.

Structure-Based Insight into the Asymmetric Bioreduction of the C=C Double Bond of alpha,beta-Unsaturated Nitroalkenes by Pentaerythritol Tetranitrate Reductase

Studies on enzymatic synthesis of chiral non-racemic 3-arylglutaric acid monoesters

Studies towards the synthesis of bicyclomycin precursors: Synthesis ofN,N′-disubstituted 2,5-diketopiperazines in solution and on solid phase

Synthesis of Islatravir Enabled by a Catalytic, Enantioselective Alkynylation of a Ketone

Synthesis of Liquid Crystalline 4H-Benzo[1,2,4]thiadiazines and Generation of Persistent Radicals