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List of works by Jens Otto Lunde Jørgensen

24-h profile of serum osteocalcin in growth hormone (GH) deficient patients with and without GH treatment

scientific article published on 01 December 1991

A model mimicking catabolic inflammatory disease; a controlled randomized study in humans

scientific article published on 05 November 2020

A multidimensional cohort study of late toxicity after intensity modulated radiotherapy for sinonasal cancer

scientific article published on 19 July 2020

A simple twist of science: the convoluted tale of ghrelin continues

scientific article published on 01 September 2006

Abdominal adiposity and physical fitness are major determinants of the age associated decline in stimulated GH secretion in healthy adults

scientific article published in June 1996

Abdominal adiposity rather than age and sex predicts mass and regularity of GH secretion in healthy adults ⬇️

scientific article published on June 1, 1997

Abdominal fat determines growth hormone-binding protein levels in healthy nonobese adults

scientific article published in January 1997

Abnormalities of whole body protein turnover, muscle metabolism and levels of metabolic hormones in patients with chronic heart failure

scientific article published in July 2006

Acipimox Acutely Increases GLP-1 Concentrations in Overweight Subjects and Hypopituitary Patients

scientific article published on 01 July 2019

Acromegaly according to the Danish National Registry of Patients: how valid are ICD diagnoses and how do patterns of registration affect the accuracy of registry data?

scientific article

Acute cardiovascular events and all-cause mortality in patients with hyperthyroidism: a population-based cohort study

scientific article

Acute effects of ghrelin administration on glucose and lipid metabolism

scientific article published on 27 November 2007

Acute exposure to GH during exercise stimulates the turnover of free fatty acids in GH-deficient men.

scientific article published on 31 October 2003

Acute intravenous acyl ghrelin infusion induces thirst but does not affect sodium excretion: two randomized, double-blind, placebo-controlled crossover studies in hypopituitary patients

scientific article published on 01 July 2019

Acute peripheral metabolic effects of intraarterial ghrelin infusion in healthy young men.

scientific article

Acute peripheral metabolic effects of intraarterial leg infusion of somatostatin in healthy young men

scientific article published on 01 June 2011

Acute peripheral tissue effects of ghrelin on interstitial levels of glucose, glycerol, and lactate: a microdialysis study in healthy human subjects

scientific article published on 16 April 2013

Acute presentation of craniopharyngioma in children and adults in a Danish national cohort ⬇️

scientific article published on December 1, 2013

Acyl Ghrelin Induces Insulin Resistance Independently of GH, Cortisol, and Free Fatty Acids

scientific article published on 15 February 2017

Adrenal Insufficiency in Corticosteroids Use: Systematic Review and Meta-Analysis.

scientific article published on 06 April 2015

Adult growth hormone deficiency

scientific article published on 01 January 1994

Age dimorphism in the association between growth-hormone status and the respiratory quotient

scientific article published in April 2002

Amino acid supplementation is anabolic during the acute phase of endotoxin-induced inflammation: A human randomized crossover trial.

scientific article

Assessment of hydration by means of bioelectrical impedance and arm muscle area during growth hormone (GH) replacement therapy: A prospective study of 130 GH-deficient patients

scientific article published on 08 March 2007

Autoimmune thyrotoxicosis developed during growth hormone (GH) treatment of an adult with childhood onset GH-deficiency. A causal relationship?

scientific article published on 01 January 1998

Beneficial effects of GH replacement therapy in adults.

scientific article published on July 1991

Beneficial effects of growth hormone treatment in GH-deficient adults

scientific article published on June 1989

Bioavailability of recombinant human growth hormone in different concentrations and formulations

scientific article published in September 1996

Biochemical assessment of disease control in acromegaly: reappraisal of the glucose suppression test in somatostatin analogue (SA) treated patients

scientific article published on 4 March 2017

Biochemical definitions of disease activity in acromegaly

scientific article published on 01 April 2003

Body composition and circulating levels of insulin, insulin-like growth factor-binding protein-1 and growth hormone (GH)-binding protein affect the pharmacokinetics of GH in adults independently of age.

scientific article

Body fluids, circadian blood pressure and plasma renin during growth hormone administration: a placebo-controlled study with two growth hormone doses in healthy adults

scientific article published on 01 December 1995

Calorigenic effects of growth hormone: the role of thyroid hormones

scientific article published on 01 April 1996

Cancer Incidence in Patients with Acromegaly: A cohort study and meta-analysis of the literature

scientific article published on 23 March 2018

Cardiovascular effects of growth hormone--with special reference to growth hormone replacement therapy

scientific article published on September 1, 1992

Cardiovascular effects of intravenous ghrelin infusion in healthy young men.

scientific article published on 14 September 2007

Circadian patterns of serum insulin-like growth factor (IGF) II and IGF binding protein 3 in growth hormone-deficient patients and age- and sex-matched normal subjects.

scientific article published in September 1990

Circadian variation in serum free and total insulin-like growth factor (IGF)-I and IGF-II in untreated and treated acromegaly and growth hormone deficiency

scientific article published on 01 January 2000

Circulating acylghrelin levels are suppressed by insulin and increase in response to hypoglycemia in healthy adult volunteers.

scientific article

Circulating levels of ghrelin and GLP-1 are inversely related during glucose ingestion

scientific article published in July 2002

Circulating levels of incretin hormones and amylin in the fasting state and after oral glucose in GH-deficient patients before and after GH replacement: a placebo-controlled study

scientific article published in November 2000

Circulating levels of pegvisomant and endogenous growth hormone during prolonged pegvisomant therapy in patients with acromegaly

scientific article published on 03 June 2013

Clinical aspects of growth hormone deficiency in adults. An overview

scientific article

Clinical indicators of adrenal insufficiency following discontinuation of oral glucocorticoid therapy: A Danish population-based self-controlled case series analysis

scientific article published on 19 February 2019

Clinical studies of IGFBP-2 by radioimmunoassay

scientific article

Concomitant, specific determination of growth hormone and pegvisomant in human serum

scientific article published on 15 June 2007

Consequences of stopping growthhormone (GH) therapy in young GH deficient patients with childhood onset disease

scientific article published on 01 February 1998

Constant intravenous ghrelin infusion in healthy young men: clinical pharmacokinetics and metabolic effects.

scientific article published on 20 February 2007

Continuation of growth hormone (GH) replacement in GH-deficient patients during transition from childhood to adulthood: a two-year placebo-controlled study

scientific article

Continuation of growth hormone (GH) substitution during fasting in GH-deficient patients decreases urea excretion and conserves protein synthesis

scientific article published in July 2001

Continuation of growth hormone (GH) therapy in GH-deficient patients during transition from childhood to adulthood: impact on insulin sensitivity and substrate metabolism.

scientific article

Continuation of growth hormone therapy versus placebo in transition-phase patients with growth hormone deficiency: impact on body composition, insulin sensitivity, and thyroid function.

scientific article

Continuous infusion versus daily injections of growth hormone (GH) for 4 weeks in GH-deficient patients

scientific article published on 01 August 1995

Continuous subcutaneous pump infusion of somatostatin analogue SMS 201-995 versus subcutaneous injection schedule in acromegalic patients

scientific article published on 01 September 1987

Conventional and novel biomarkers of treatment outcome in patients with acromegaly: discordant results after somatostatin analog treatment compared with surgery.

scientific article published on 2 September 2010

Cotreatment of acromegaly with a somatostatin analog and a growth hormone receptor antagonist

scientific article published on 26 July 2005

Cotreatment with pegvisomant and a somatostatin analog (SA) in SA-responsive acromegalic patients

scientific article published in June 2011

Cushing's syndrome in children and adolescents: a Danish nationwide population-based cohort study

scientific article

Decreased lipid intermediate levels and lipid oxidation rates despite normal lipolysis in patients with hypothyroidism

scientific article published on August 2010

Dehydroepiandrosterone substitution in female adrenal failure: no impact on endothelial function and cardiovascular parameters despite normalization of androgen status

scientific article published in March 2007

Dehydroepiandrosterone supplementation in women with adrenal failure: impact on twenty-four hour GH secretion and IGF-related parameters

scientific article published on April 2004

Detection of growth hormone abuse in sport

scientific article published on 06 March 2007

Determinants of serum insulin-like growth factor I in growth hormone deficient adults as compared to healthy subjects

scientific article published in April 1998

Development of ACRODAT®, a new software medical device to assess disease activity in patients with acromegaly.

scientific article published on 8 September 2017

Development of a questionnaire encompassing indicators of distress: a tool for use with women in surgical continuity of care for breast cancer

scientific article published on 18 November 2014

Different effects of continuous and intermittent patterns of growth hormone administration on lipoprotein levels in growth hormone-deficient patients

scientific article published on 01 January 1998

Differential effects of growth hormone and prednisolone on energy metabolism and leptin levels in humans

scientific article published on 01 January 1998

Differential regulation of lipid and protein metabolism in obese vs. lean subjects before and after a 72-h fast

scientific article published on 31 May 2016

Direct effects of TNF-α on local fuel metabolism and cytokine levels in the placebo-controlled, bilaterally infused human leg: increased insulin sensitivity, increased net protein breakdown, and increased IL-6 release.

scientific article published on 8 July 2013

Direct effects of locally administered lipopolysaccharide on glucose, lipid, and protein metabolism in the placebo-controlled, bilaterally infused human leg.

scientific article published on 29 March 2013

Discontinuation of estrogen replacement therapy in GH-treated hypopituitary women alters androgen status and IGF-I.

scientific article published in May 2005

Discontinuation of hormone replacement therapy in young GH-treated hypopituitary women increases liver enzymes

scientific article published on 5 August 2009

Dissecting adipose tissue lipolysis: molecular regulation and implications for metabolic disease

scientific article

Dose dependency of the pharmacokinetics and acute lipolytic actions of growth hormone.

scientific article published in October 2002

Dose-response effects of free fatty acids on amino acid metabolism and ureagenesis.

scientific article published on 31 October 2007

Dose-response studies on the metabolic effects of a growth hormone pulse in humans

scientific article published on 01 February 1992

Dose-response studies with biosynthetic human growth hormone (GH) in GH-deficient patients

scientific article published in July 1988

Ectopic ACTH syndrome: discrepancy between somatostatin receptor status in vivo and ex vivo, and between immunostaining and gene transcription for POMC and CRH.

scientific article

Effects of 12 months of growth hormone (GH) treatment on calciotropic hormones, calcium homeostasis, and bone metabolism in adults with acquired GH deficiency: a double blind, randomized, placebo-controlled study

scientific article published on 01 September 1996

Effects of Cortisol on Carbohydrate, Lipid, and Protein Metabolism: Studies of Acute Cortisol Withdrawal in Adrenocortical Failure

scientific article published on 03 July 2007

Effects of GH in human muscle and fat.

scientific article

Effects of GH on urea, glucose and lipid metabolism, and insulin sensitivity during fasting in GH-deficient patients

scientific article

Effects of GH replacement in young patients with childhood onset GH deficiency

scientific article published in May 2002

Effects of GH replacement therapy in adults on serum levels of leptin and ghrelin: the role of lipolysis.

scientific article published in October 2005

Effects of Prednisolone on Serum and Tissue Fluid IGF-I Receptor Activation and Post-Receptor Signaling in Humans.

scientific article

Effects of a 7-day continuous infusion of octreotide on circulating levels of growth factors and binding proteins in growth hormone (GH)-treated GH-deficient patients

scientific article published on 01 December 1999

Effects of a growth hormone pulse on total and forearm substrate fluxes in humans

scientific article published in January 1990

Effects of free fatty acids, growth hormone and growth hormone receptor blockade on serum ghrelin levels in humans

scientific article published on 01 May 2007

Effects of growth hormone (GH) administration on functional hepatic nitrogen clearance: studies in normal subjects and GH-deficient patients

scientific article published on 01 May 1994

Effects of growth hormone (GH) on plasma bone Gla protein in GH-deficient adults

scientific article published on 01 April 1990

Effects of growth hormone administration on fuel oxidation and thyroid function in normal man.

scientific article published in July 1992

Effects of growth hormone administration on protein dynamics and substrate metabolism during 4 weeks of dietary restriction in obese women

scientific article published on 01 March 2000

Effects of growth hormone and insulin-like growth factor-I singly and in combination on in vivo capacity of urea synthesis, gene expression of urea cycle enzymes, and organ nitrogen contents in rats

scientific article published on 01 April 1997

Effects of growth hormone on body composition in adults

scientific article published on 01 January 1990

Effects of growth hormone on glucose and fat metabolism in human subjects.

scientific article published on March 2007

Effects of growth hormone on glucose metabolism

scientific article published on January 1991

Effects of growth hormone on glucose, lipid, and protein metabolism in human subjects

scientific article published on 24 February 2009

Effects of growth hormone on serum lipids and lipoproteins: possible significance of increased peripheral conversion of thyroxine to triiodothyronine

scientific article published on 01 August 1996

Effects of growth hormone replacement therapy on IGF-related parameters and on the pituitary-gonadal axis in GH-deficient males. A double-blind, placebo-controlled crossover study

scientific article published in January 1998

Effects of growth hormone therapy on thyroid function of growth hormone-deficient adults with and without concomitant thyroxine-substituted central hypothyroidism

scientific article published on 01 December 1989

Effects of leptin on basal and FSH stimulated steroidogenesis in human granulosa luteal cells

scientific article

Effects of long-term growth hormone (GH) and triiodothyronine (T3) administration on functional hepatic nitrogen clearance in normal man

scientific article published on 01 March 1996

Effects of lowering circulating free fatty acid levels on protein metabolism in adult growth hormone deficient patients

scientific article published in December 2002

Effects of octreotide on insulin-like growth factor I and metabolic indices in growth hormone-treated growth hormone-deficient patients

scientific article published on November 1993

Effects of short-term prednisolone treatment on indices of lipolysis and lipase signaling in abdominal adipose tissue in healthy humans

scientific article published on 29 June 2019

Elevated regional lipolysis in hyperthyroidism

scientific article published in October 2002

Epidemiology of Cushing's syndrome

scientific article

Erythropoietin administration acutely stimulates resting energy expenditure in healthy young men.

scientific article published on 12 January 2012

Evaluation of functional erythropoietin receptor status in skeletal muscle in vivo: acute and prolonged studies in healthy human subjects

scientific article

Evaluation of growth hormone stimulation tests in cured acromegalic patients

scientific article published in December 2003

Evening versus morning injections of growth hormone (GH) in GH-deficient patients: effects on 24-hour patterns of circulating hormones and metabolites

scientific article published in January 1990

Evidence against a role for insulin-signaling proteins PI 3-kinase and Akt in insulin resistance in human skeletal muscle induced by short-term GH infusion

scientific article published on 31 August 2004

Evidence supporting a direct suppressive effect of growth hormone on serum IGFBP-1 levels. Experimental studies in normal, obese and GH-deficient adults.

scientific article published in February 1999

Evidence-based approach to growth hormone replacement therapy in adults, with special emphasis on body composition.

scientific article

Exercise and fasting activate growth hormone-dependent myocellular signal transducer and activator of transcription-5b phosphorylation and insulin-like growth factor-I messenger ribonucleic acid expression in humans.

scientific article published on 9 June 2010

Expansion of extracellular volume and suppression of atrial natriuretic peptide after growth hormone administration in normal man

scientific article published on 01 April 1991

Expression of leptin receptor isoforms and effects of leptin on the proliferation and hormonal secretion in human pituitary adenomas.

scientific article

Fasting in healthy subjects is associated with intrahepatic accumulation of lipids as assessed by 1H-magnetic resonance spectroscopy

scientific article published in April 2008

Fasting increases human skeletal muscle net phenylalanine release and this is associated with decreased mTOR signaling

scientific article

Fasting unmasks a strong inverse association between ghrelin and cortisol in serum: studies in obese and normal-weight subjects

scientific article published on 2 November 2004

Fasting, but not exercise, increases adipose triglyceride lipase (ATGL) protein and reduces G(0)/G(1) switch gene 2 (G0S2) protein and mRNA content in human adipose tissue

scientific article published on 25 May 2011

Fibroblast Activation Protein is a GH Target: A Prospective Study of Patients with Acromegaly Before and After Treatment

scientific article published on 01 January 2020

Fifteen-year nationwide trends in systemic glucocorticoid drug use in Denmark

scientific article published on 01 September 2019

Fracture risk is increased in patients with GH deficiency or untreated prolactinomas - a case-control study

scientific article published on 01 February 2002

Free fatty acids decrease circulating ghrelin concentrations in humans

scientific article published on 01 May 2006

Free fatty acids inhibit growth hormone/signal transducer and activator of transcription-5 signaling in human muscle: a potential feedback mechanism.

scientific article published on 10 March 2009

Frequent occurrence of pituitary apoplexy in patients with non-functioning pituitary adenoma

scientific article published in March 2006

Fuel metabolism in growth hormone-deficient adults

scientific article published on October 1995

Fuel metabolism, energy expenditure, and thyroid function in growth hormone-treated obese women: a double-blind placebo-controlled study

scientific article published on 01 July 1994

GH receptor signaling in skeletal muscle and adipose tissue in human subjects following exposure to an intravenous GH bolus

scientific article published on 06 June 2006

GH signaling in human adipose and muscle tissue during 'feast and famine': amplification of exercise stimulation following fasting compared to glucose administration

scientific article published in June 2015

GH signaling in skeletal muscle and adipose tissue in healthy human subjects: impact of gender and age

scientific article published on 27 August 2014

GH stimulation tests: evaluation of GH responses to heat test versus insulin-tolerance test

scientific article published in December 1998

GH strongly affects serum concentrations of mannan-binding lectin: evidence for a new IGF-I independent immunomodulatory effect of GH.

scientific article published in November 2001

GH-Replacement Therapy in Adults ⬇️

scientific article published on January 1, 1991

Gender differences in growth hormone response to exercise before and after rhGH administration and the effect of rhGH on the hormone profile of fit normal adults

scientific article published on 01 March 2005

Gene expression in skeletal muscle after an acute intravenous GH bolus in human subjects: identification of a mechanism regulating ANGPTL4.

scientific article published on 20 April 2013

Gene expression of a truncated and the full-length growth hormone (GH) receptor in subcutaneous fat and skeletal muscle in GH-deficient adults: impact of GH treatment

scientific article published on 01 February 2001

Gene expression of the GH receptor in subcutaneous and intraabdominal fat in healthy females: relationship to GH-binding protein

scientific article published in June 2004

Gene transcription of receptors for growth hormone-releasing peptide and somatostatin in human pituitary adenomas

scientific article published on 01 August 1998

Ghrelin Does Not Directly Stimulate Secretion of Glucagon-like Peptide-1

scientific article published on 01 January 2020

Ghrelin immunoreactivity in human plasma is suppressed by somatostatin

scientific journal article

Ghrelin infusion in humans induces acute insulin resistance and lipolysis independent of growth hormone signaling

scientific article published on 5 September 2008

Ghrelin- and GH-induced insulin resistance: no association with retinol-binding protein-4.

scientific article published on 21 May 2013

Giant prolactinoma presenting as a skull base tumor with erosion of the cervical vertebrae: pronounced responsiveness to dopamine agonist treatment

scientific article

Glucose and Fat Metabolism in Acromegaly: From Mice Models to Patient Care

scientific article published on 29 April 2015

Growth Hormone (GH)-Deficiency in Adults: Clinical Features and Effects of GH Substitution

scientific article published on 01 October 1994

Growth Hormone and Insulin Signaling in Acromegaly: Impact of Surgery Versus Somatostatin Analog Treatment

scientific article

Growth Hormone and Obesity

scientific article published on 16 April 2020

Growth hormone (GH) effects on bone and collagen turnover in healthy adults and its potential as a marker of GH abuse in sports: a double blind, placebo-controlled study. The GH-2000 Study Group

scientific article published on 01 April 2000

Growth hormone (GH) status is an independent determinant of serum levels of cholesterol and triglycerides in healthy adults

scientific article published in September 1999

Growth hormone (GH) substitution for one year normalizes elevated GH-binding protein levels in GH-deficient adults secondary to a reduction in body fat. A placebo-controlled trial

scientific article published in April 1998

Growth hormone (GH) substitution in GH-deficient patients inhibits 11beta-hydroxysteroid dehydrogenase type 1 messenger ribonucleic acid expression in adipose tissue.

scientific article published on 20 December 2005

Growth hormone (GH) therapy in GH-deficient patients, the plasma factor VIII-von Willebrand factor complex, and capillary fragility. A double-blind, placebo-controlled crossover study

scientific article published on 01 June 1990

Growth hormone (GH) treatment increases serum insulin-like growth factor binding protein-3, bone isoenzyme alkaline phosphatase and forearm bone mineral content in young adults with GH deficiency of childhood onset

scientific article published on 01 July 1994

Growth hormone (GH)-induced insulin resistance is rapidly reversible: an experimental study in GH-deficient adults

scientific article published on 25 May 2011

Growth hormone acts along PPARγ-FSP27 axis to stimulate lipolysis in human adipocytes

scientific article published on 16 October 2018

Growth hormone and glucose homeostasis

scientific article

Growth hormone controls lipolysis by regulation of FSP27 expression

scientific article published on 01 December 2018

Growth hormone deficiency and hyperthermia during exercise: a controlled study of sixteen GH-deficient patients

scientific article published on November 1995

Growth hormone increases vascular cell adhesion molecule 1 expression: in vivo and in vitro evidence

scientific article published on February 2004

Growth hormone prevents prednisolone-induced increase in functional hepatic nitrogen clearance in normal man

scientific article published on 01 November 1997

Growth hormone receptor expression and function in pituitary adenomas

scientific article

Growth hormone secretory capacity and serum insulin-like growth factor I levels in primary infertile, anovulatory women with regular menses.

scientific article published on January 1992

Growth hormone signaling and action in obese versus lean human subjects

scientific article published on 21 December 2018

Growth hormone signaling in muscle and adipose tissue of obese human subjects: associations with measures of body composition and interaction with resveratrol treatment

scientific article published on December 2014

Growth hormone signaling in vivo in human muscle and adipose tissue: impact of insulin, substrate background, and growth hormone receptor blockade.

scientific article published on 6 May 2008

Growth hormone therapy in adults

scientific article published on 01 July 2001

Growth hormone treatment during pregnancy in a growth hormone-deficient woman

scientific article published on 01 June 1995

Growth hormone treatment in adults with adult-onset growth hormone deficiency increases iliac crest trabecular bone turnover: a 1-year, double-blind, randomized, placebo-controlled study

scientific article published on 01 February 2000

Growth hormone treatment in adults: is there a true gender difference?

scientific article

Growth hormone versus placebo treatment for one year in growth hormone deficient adults: increase in exercise capacity and normalization of body composition.

scientific article

Growth hormone-induced insulin resistance in human subjects involves reduced pyruvate dehydrogenase activity.

scientific article published on 22 November 2013

Growth hormone-induced insulin resistance is associated with increased intramyocellular triglyceride content but unaltered VLDL-triglyceride kinetics.

scientific article published on 28 November 2006

Heart valve disease among patients with hyperprolactinemia: a nationwide population-based cohort study

scientific article

Hepatic amino nitrogen conversion and organ N-contents in hypothyroidism, with thyroxine replacement, and in hyperthyroid rats

scientific article published on 01 February 1997

Hepatic amino- to urea-N clearance and forearm amino-N exchange during hypoglycemic and euglycemic hyperinsulinemia in normal man

scientific article published on 01 May 1999

High-dose resveratrol supplementation in obese men: an investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition.

scientific article published on 28 November 2012

Hormone and Cytokine Responses to Repeated Endotoxin Exposures-No Evidence of Endotoxin Tolerance After 5 Weeks in Humans.

scientific article published on July 2015

Hormone and Cytokine Responses to Repeated Endotoxin Exposures-No Evidence of Endotoxin Tolerance After 5 Weeks in Humans: Reply.

scientific article

Hypercortisolism in Newly Diagnosed Type 2 Diabetes: A Prospective Study of 384 Newly Diagnosed Patients

scientific article published on 06 December 2018

Hypersecretion of the alpha-subunit in clinically non-functioning pituitary adenomas: Diagnostic accuracy is improved by adding alpha-subunit/gonadotropin ratio to levels of alpha-subunit.

scientific article

Hyperthyroidism and cation pumps in human skeletal muscle

scientific article published on 14 December 2004

Hyperthyroidism is associated with suppressed circulating ghrelin levels

scientific article

Hyponatremia and mortality risk: a Danish cohort study of 279 508 acutely hospitalized patients

scientific article

Hypopituitarism and mortality in pituitary adenoma.

scientific article published in July 2006

Hypothesis: Extra-hepatic acromegaly: a new paradigm?

scientific article published on 02 November 2010

Hypothyroidism and hyperthyroidism and breast cancer risk: a nationwide cohort study

scientific article

Identification of new biomarkers of low-dose GH replacement therapy in GH-deficient patients.

scientific article

Impact of GH administration on athletic performance in healthy young adults: A systematic review and meta-analysis of placebo-controlled trials

scientific article

Impact of GH substitution on exercise capacity and muscle strength in GH-deficient adults: a meta-analysis of blinded, placebo-controlled trials

scientific article published on 28 March 2009

Impact of GHBP interference on estimates of GH and GH pharmacokinetics

scientific article published on 01 December 2002

Impact of fasting on growth hormone signaling and action in muscle and fat.

scientific article published on 9 December 2008

Impact of growth hormone administration on other hormonal axes

scientific article

Impact of growth hormone receptor blockade on substrate metabolism during fasting in healthy subjects

scientific article

Incidence and late prognosis of cushing's syndrome: a population-based study

scientific article

Incidence of GH deficiency - a nationwide study

scientific article published in July 2006

Incidence of craniopharyngioma in Denmark (n = 189) and estimated world incidence of craniopharyngioma in children and adults

scientific article published on 19 February 2011

Increased levels but preserved diurnal variation of serum leptin in GH-deficient patients: lack of impact of different modes of GH administration

scientific article published in June 1998

Increased lipolysis after infusion of acylated ghrelin: a randomized, double-blinded placebo-controlled trial in hypopituitary patients

scientific article published on 20 July 2020

Increased myocardial contractility following growth hormone administration in normal man. An echocardiographic study

scientific article published on 01 April 1988

Increased protein turnover and proteolysis is an early and primary feature of short-term experimental hyperthyroidism in healthy women

scientific article published on 15 July 2008

Increased pulsatile, but not basal, growth hormone secretion rates and plasma insulin-like growth factor I levels during the periovulatory interval in normal women

scientific article published on 01 May 1998

Inflammatory adipokines contribute to insulin resistance in active acromegaly and respond differently to different treatment modalities

scientific article published on 22 November 2013

Influence of growth hormone and androgens on body composition in adults

scientific article

Influence of growth hormone on glucose-induced glucose uptake in normal men as assessed by the hyperglycemic clamp technique

scientific article published on 01 February 1989

Insulin and GH signaling in human skeletal muscle in vivo following exogenous GH exposure: impact of an oral glucose load

scientific article (publication date: 3 May 2011)

Insulin resistance after a 72-h fast is associated with impaired AS160 phosphorylation and accumulation of lipid and glycogen in human skeletal muscle.

scientific article published on 25 October 2011

Insulin resistance induced by growth hormone is linked to lipolysis and associated with suppressed pyruvate dehydrogenase activity in skeletal muscle: a 2 × 2 factorial, randomised, crossover study in human individuals

scientific article published on 18 September 2020

Insulin-like growth factor (IGF) I, -II, and IGF binding protein-3 and risk of ischemic stroke

scientific article published on 30 August 2005

Insulin-like growth factor I administration induces fluid and sodium retention in healthy adults: possible involvement of renin and atrial natriuretic factor

scientific article published on 01 February 2000

Insulin-like growth factors (IGF)-I and -II and IGF binding protein-1, -2, and -3 in patients with acromegaly before and after adenomectomy

scientific article published on 01 May 1994

Intact pituitary function is decisive for the catabolic response to TNF-α: studies of protein, glucose and fatty acid metabolism in hypopituitary and healthy subjects

scientific article

Jens Sandahl Christiansen, DMSci, FRCPI (1948-2015).

scientific article

Kinetics and utilization of lipid sources during acute exercise and acipimox

scientific article published on 03 June 2014

L-arginine and insulin-tolerance tests in the diagnosis of adult growth hormone deficiency: influence of confounding factors

scientific article published in January 1998

L-arginine-induced growth hormone secretion is not influenced by co-infusion of the nitric oxide synthase inhibitor N-monomethyl- L-arginine in healthy men

scientific article published on 01 February 1999

Lack of effects of hyperglycemia on the disposal of 3-hydroxybutyrate in insulin-dependent diabetic patients.

scientific article published on December 1990

Lack of effects of hypoglycemia on glucose absorption in healthy men

scientific article published on 01 October 1992

Lack of observed association between high plasma osteoprotegerin concentrations and ischemic stroke risk in a healthy population

scientific article published on 30 October 2008

Local administration of growth hormone stimulates tendon collagen synthesis in elderly men

scientific article published on 06 September 2012

Long-term DHEA substitution in female adrenocortical failure, body composition, muscle function, and bone metabolism: a randomized trial

scientific article published on 23 May 2011

Long-term effects of continuous subcutaneous infusion versus daily subcutaneous injections of growth hormone (GH) on the insulin-like growth factor system, insulin sensitivity, body composition, and bone and lipoprotein metabolism in GH-deficient ad

scientific article

Long-term effects of growth hormone (GH) on body fluid distribution in GH deficient adults: a four months double blind placebo controlled trial

scientific article published on 01 January 1999

Long-term efficacy and safety of pegvisomant in combination with long-acting somatostatin analogs in acromegaly

scientific article published on 17 June 2014

Long-term efficacy and tolerability of octreotide treatment in acromegaly

scientific article (publication date: September 1992)

Long-term growth hormone treatment in growth hormone deficient adults ⬇️

scientific article published on November 1, 1991

Management of endocrine disease: Mortality remains increased in Cushing's disease despite biochemical remission: a systematic review and meta-analysis

scientific article published on April 2015

Marked effects of sustained low growth hormone (GH) levels on day-to-day fuel metabolism: studies in GH-deficient patients and healthy untreated subjects

scientific article published on 01 December 1993

Metabolic consequences of GH deficiency.

scientific article

Metabolic effects and pharmacokinetics of a growth hormone pulse in healthy adults: relation to age, sex, and body composition

scientific article published in November 1997

Metabolic effects of GH: a rationale for continued GH treatment of GH-deficient adults after cessation of linear growth.

scientific article

Metabolic effects of growth hormone in humans.

scientific article published on October 1995

Modulation of basal glucose metabolism and insulin sensitivity by growth hormone and free fatty acids during short-term fasting

scientific article

Molecular adaptations in human subcutaneous adipose tissue after ten weeks of endurance exercise training in healthy males

scientific article published on 20 December 2018

Mortality in Cushing's syndrome: a systematic review and meta-analysis.

scientific article

Multisystem morbidity and mortality in Cushing's syndrome: a cohort study

scientific article published on 26 March 2013

Muscle mass and function in thyrotoxic patients before and during medical treatment

scientific article published on 01 December 1999

NPH insulin administration by means of a pen injector.

scientific article

No Beneficial Effects of Resveratrol on the Metabolic Syndrome: A Randomized Placebo-Controlled Clinical Trial

scientific article published on 9 February 2017

No effect of 10 weeks erythropoietin treatment on lipid oxidation in healthy men

scientific article published on 01 October 2020

No evidence of insulin-like growth factor-binding protein 3 proteolysis during a maximal exercise test in elite athletes

scientific article published on 01 February 2001

No influence of prednisolone on IGFBP-3 proteolysis in healthy young men.

scientific article published in January 2001

Normal Physiology of Growth Hormone in Adults

scientific article published on 24 April 2015

Normal basal and insulin-stimulated fuel metabolism in lean women with the polycystic ovary syndrome.

scientific article

Novel serum biomarkers for erythropoietin use in humans: a proteomic approach.

scientific article published on 21 October 2010

Novel serum protein biomarkers indicative of growth hormone doping in healthy human subjects

scientific article

Peroxisome proliferator-activated receptor gamma (PPAR) agonism reduces the insulin-stimulated increase in circulating interleukin-6 in GH replaced GH-deficient adults

scientific article published on 3 December 2008

Peroxisome proliferator-activated receptor gamma agonism modifies the effects of growth hormone on lipolysis and insulin sensitivity

scientific article published on 10 March 2008

Pharmacological antilipolysis restores insulin sensitivity during growth hormone exposure

scientific article published in October 2001

Pharmacological aspects of growth hormone replacement therapy: route, frequency and timing of administration

scientific article published on January 1990

Physical exercise increases autophagic signaling through ULK1 in human skeletal muscle

scientific article published on 12 February 2015

Plasma ghrelin levels during exercise in healthy subjects and in growth hormone-deficient patients

scientific article published in July 2002

Plasma growth hormone in acromegalic patients. Demonstration of highly reproducible diurnal profiles in individual patients

scientific article published on 01 September 1987

Prescription duration and treatment episodes in oral glucocorticoid users: application of the parametric waiting time distribution

scientific article published on 16 November 2017

Preservation of inherent diurnal serum insulin-like growth factor binding protein 1 pattern during low dose GH infusion

scientific article published on 01 October 1992

Prevalence and predictors of distress in women taking part in surgical continuity of care for breast cancer: A cohort study.

scientific article published on 14 March 2016

Prevalence of lifestyle characteristics in glucocorticoid users and non-users: a Danish population-based cross-sectional study

scientific article published on 28 October 2019

Prof. Jens Sandahl Christiansen

scientific article published on 11 January 2016

Prolonged erythropoietin treatment does not impact gene expression in human skeletal muscle

scientific article published on 25 February 2015

Prolonged fasting-induced metabolic signatures in human skeletal muscle of lean and obese men

scientific article published in PLoS ONE

Pulsatile versus continuous intravenous administration of growth hormone (GH) in GH-deficient patients: effects on circulating insulin-like growth factor-I and metabolic indices

scientific article published on 01 June 1990

Recurrence of hyperprolactinemia after withdrawal of dopamine agonists: systematic review and meta-analysis.

scientific article

Reduced expression of uncoupling protein 2 in adipose tissue in patients with hypothyroidism.

scientific article published on 28 April 2010

Reduced mRNA and protein expression of perilipin A and G0/G1 switch gene 2 (G0S2) in human adipose tissue in poorly controlled type 2 diabetes

scientific article published on 24 April 2012

Reduction in sella turcica volume. An effect of long-term treatment with the somatostatin analogue, SMS 201-995, in acromegalic patients

scientific article

Redundancy in regulation of lipid accumulation in skeletal muscle during prolonged fasting in obese men

scientific article published on 01 November 2019

Regulation of lipoprotein lipase and hormone-sensitive lipase activity and gene expression in adipose and muscle tissue by growth hormone treatment during weight loss in obese patients

scientific article published in July 2000

Response to the Letter by Lindholm, et al

scientific article published on 01 August 2015

Responses of markers of bone and collagen turnover to exercise, growth hormone (GH) administration, and GH withdrawal in trained adult males

scientific article published on 01 January 2000

Responses of the growth hormone (GH) and insulin-like growth factor axis to exercise, GH administration, and GH withdrawal in trained adult males: a potential test for GH abuse in sport

scientific article published on 01 October 1999

Resting metabolic rate in healthy adults: relation to growth hormone status and leptin levels

scientific article published in September 1998

Resveratrol in metabolic health: an overview of the current evidence and perspectives.

scientific article

Resveratrol reduces the levels of circulating androgen precursors but has no effect on, testosterone, dihydrotestosterone, PSA levels or prostate volume. A 4-month randomised trial in middle-aged men

scientific article published on 04 May 2015

Risk of cancer in patients with thyroid disease and venous thromboembolism

scientific article published on 02 August 2018

Safety aspects of growth hormone replacement in adults.

scientific article

Serum free insulin-like growth factor-I in growth hormone-deficient adults before and after growth hormone replacement

scientific article published in August 1997

Serum ghrelin levels are increased in hypothyroid patients and become normalized by L-thyroxine treatment

scientific article published in April 2008

Serum ghrelin levels are suppressed in hypopituitary patients following insulin-induced hypoglycaemia irrespective of GH status.

scientific article

Serum insulin-like growth factor I levels in growth hormone-deficient adults: influence of sex steroids.

scientific article

Serum leptin concentrations during short-term administration of growth hormone and triiodothyronine in healthy adults: a randomised, double-blind placebo-controlled study

scientific article

Serum leptin is increased in growth hormone—deficient adults: Relation to body composition and effects of placebo-controlled growth hormone therapy for 1 year ⬇️

scientific article published on July 1, 1997

Serum leptin levels and leptin expression in growth hormone (GH)-deficient and healthy adults: influence of GH treatment, gender, and fasting

scientific article published in December 1998

Serum levels of bioactive IGF1 and physiological markers of ageing in healthy adults

scientific article published on 21 December 2013

Serum osteocalcin and bone isoenzyme alkaline phosphatase in growth hormone-deficient patients: dose-response studies with biosynthetic human GH

scientific article published on 01 February 1991

Serum profiles and short-term metabolic effect of pituitary and authentic biosynthetic human growth hormone in man. A double-blind cross-over study.

scientific article

Serum proteome changes in acromegalic patients following transsphenoidal surgery: novel biomarkers of disease activity.

scientific article

Serum proteomic changes after randomized prolonged erythropoietin treatment and/or endurance training: detection of novel biomarkers.

scientific article published on 13 February 2015

Sex differences in acromegaly at diagnosis: A nationwide cohort study and meta-analysis of the literature

scientific article published on 11 December 2020

Sex steroids and the growth hormone/insulin-like growth factor-I axis in adults.

scientific article

Short and long-term cardiovascular effects of growth hormone therapy in growth hormone deficient adults.

scientific article

Short-term acipimox treatment is associated with decreased cardiac parasympathetic modulation

scientific article published on 23 July 2017

Short-term changes in serum insulin-like growth factors (IGF) and IGF binding protein 3 after different modes of intravenous growth hormone (GH) exposure in GH-deficient patients

scientific article published on 01 March 1991

Short-term effects of growth hormone on fuel oxidation and regional substrate metabolism in normal man

scientific article published on 01 April 1990

Short-term growth hormone treatment in girls with Turner syndrome decreases fat mass and insulin sensitivity: a randomized, double-blind, placebo-controlled, crossover study

scientific article published in November 2002

Short-term tools to measure responsiveness to growth hormone replacement.

scientific article

Simultaneous determination of β-hydroxybutyrate and β-hydroxy-β-methylbutyrate in human whole blood using hydrophilic interaction liquid chromatography electrospray tandem mass spectrometry

scientific article published on 29 August 2013

Skin morphological changes in growth hormone deficiency and acromegaly

scientific article published in August 2001

Soft tissue changes in adults with acquired growth hormone deficiency during substitution treatment. A double-blind, randomized, placebo-controlled study after a year of treatment

scientific article published on July 7, 1997

Soluble Klotho: a possible predictor of quality of life in acromegaly patients

scientific article published on 24 April 2020

Somatopause and Adiposity ⬇️

scientific article published on January 1, 1997

Somatostatin enhances insulin-stimulated glucose uptake in the perfused human forearm

scientific article published on 01 June 1995

Somatropin and glucose homeostasis: considerations for patient management.

scientific article

Stimulation of the 150-kilodalton insulin-like growth factor-binding protein-3 ternary complex by continuous and pulsatile patterns of growth hormone (GH) administration in GH-deficient patients

scientific article published on 01 November 2000

Stress hormone release is a key component of the metabolic response to lipopolysaccharide: studies in hypopituitary and healthy subjects

scientific article published on 25 August 2016

Subcutaneous degradation of biosynthetic human growth hormone in growth hormone deficient patients

scientific article published on 01 May 1988

Substrate Metabolism and Insulin Sensitivity During Fasting in Obese Human Subjects: Impact of GH Blockade

scientific article published on 18 January 2017

Substrate metabolism during modest hyperinsulinemia in response to isolated hyperketonemia in insulin-dependent diabetic subjects

scientific article published on 01 December 1990

Sustained AS160 and TBC1D1 phosphorylations in human skeletal muscle 30 min after a single bout of exercise.

scientific article published on 29 May 2014

Systemic glucocorticoid use in Denmark: a population-based prevalence study

scientific article published on 29 May 2017

Targeting either GH or IGF-I during somatostatin analogue treatment in patients with acromegaly: a randomized multicentre study

scientific article

Ten weeks of aerobic training does not result in persistent changes in VLDL triglyceride turnover or oxidation in healthy men

scientific article published on 12 August 2014

Testing for growth hormone deficiency in adults -- how to respond?

scientific article published on 01 January 2003

The Circulating IGF System in Hepatocellular Carcinoma: The Impact of Liver Status and Treatment

scientific article

The acute effect of a physiological bolus of growth hormone (GH) on insulin signalling pathways in striated muscle in healthy volunteers.

scientific article published on 20 August 2009

The acute effects of growth hormone in adipose tissue is associated with suppression of antilipolytic signals

scientific article published on 01 February 2020

The decisive role of free fatty acids for protein conservation during fasting in humans with and without growth hormone

scientific article published in September 2003

The effect of 30 months of low-dose replacement therapy with recombinant human growth hormone (rhGH) on insulin and C-peptide kinetics, insulin secretion, insulin sensitivity, glucose effectiveness, and body composition in GH-deficient adults

scientific article published in November 2000

The effect of four weeks of supraphysiological growth hormone administration on the insulin-like growth factor axis in women and men. GH-2000 Study Group

scientific article published on 01 November 2000

The effect of growth hormone (GH) therapy on urinary pyridinoline cross-links in GH-deficient adults ⬇️

scientific article published on December 1, 1991

The effect of growth hormone on the insulin-like growth factor system during fasting

scientific article published in July 2003

The effect of long-term pharmacological antilipolysis on substrate metabolism in growth hormone (GH)-substituted GH-deficient adults

scientific article published in July 2002

The effect of submaximal exercise on immuno- and bioassayable IGF-I activity in patients with GH-deficiency and healthy subjects

scientific article published in August 2005

The effect of the deterioration of insulin sensitivity on beta-cell function in growth-hormone-deficient adults following 4-month growth hormone replacement therapy

scientific article published in April 1999

The experience of distress in relation to surgical treatment and care for breast cancer: An interview study.

scientific article

The ghrelin response to exercise before and after growth hormone administration

scientific article published on 10 October 2006

The growth hormone (GH)-insulin-like growth factor axis during testosterone replacement therapy in GH-treated hypopituitary males

scientific article published in April 2001

The impact of pegvisomant treatment on substrate metabolism and insulin sensitivity in patients with acromegaly

scientific article published on 6 March 2007

The management of adult growth hormone deficiency syndrome

scientific article published in October 2008

The protein-retaining effects of growth hormone during fasting involve inhibition of muscle-protein breakdown

scientific article

The role of nitric oxide in L-arginine-stimulated growth hormone release.

scientific article

Three years of growth hormone treatment in growth hormone-deficient adults: near normalization of body composition and physical performance

scientific article published on March 1994

Thyroid Function during Growth Hormone Therapy ⬇️

scientific article published on 01 January 1992

Thyroid hormone increases mannan-binding lectin levels

scientific article published in November 2005

Time-course effects of physiological free fatty acid surges on insulin sensitivity in humans

scientific article published on 11 October 2010

Type I and III procollagen propeptides in growth hormone-deficient patients: effects of increasing doses of GH.

scientific article published in March 1991

Unacylated Ghrelin Does Not Acutely Affect Substrate Metabolism or Insulin Sensitivity in Men With Type 2 Diabetes

scientific article published on 01 June 2019

Use of Glucocorticoids and Risk of Venous Thromboembolism

scientific article published on 01 May 2013

Validity of the International Classification of Diseases, 10th revision discharge diagnosis codes for hyponatraemia in the Danish National Registry of Patients

scientific article

Variability in growth hormone stimulation tests

scientific article

Very short term dehydroepiandrosterone treatment in female adrenal failure: impact on carbohydrate, lipid and protein metabolism

scientific article

Weight loss increases circulating levels of ghrelin in human obesity

scientific article published in February 2002

Whole body and forearm substrate metabolism in hyperthyroidism: evidence of increased basal muscle protein breakdown

scientific article published on 18 January 2005

Whole body metabolic effects of prolonged endurance training in combination with erythropoietin treatment in humans: a randomized placebo controlled trial

scientific article published on 6 August 2013

[Acromegaly and symptoms of the motor apparatus] ⬇️

scientific article published on 01 November 2018

[Acromegaly: new principles for treatment]

scientific article published on 01 March 2007

[Acromegaly] ⬇️

scientific article published on 01 December 2018

[Copeptin is a new diagnostic biomarker for diabetes insipidus] ⬇️

scientific article published on 01 December 2020

[Diagnostics and new treatment methods of syndrome of inappropriate antidiuretic hormone secretion (SIADH)]

scientific article published on 01 April 2012

[Dopamin agonist treatment and fibrotic heart valve disease in hyperprolactinaemia patients]

[Growth hormone deficiency in adults--clinical picture and treatment]

scientific article published on 01 January 1995

[Growth hormone treatment of men with reduced sperm quality]

scientific article published on 01 January 1998

[Insulin-like growth factors and growth hormone]

scientific article published on 01 September 1990

[Long-term treatment with octreotide of patients with acromegaly]

scientific article published on 01 August 1993

[Medical co-treatment af acromegaly with a somatostatin analogue and a growth hormone receptor antagonist]

scientific article published on 01 March 2007

[New diagnostic methods in renal artery stenosis]

scientific article published on 01 February 1997

[Resectability of papillary and pancreatic cancer assessed by ultrasonography and computer tomography]

scientific article published on 01 February 1997

[Treatment of acromegaly in Aarhus University Hospital. A retrospective investigation of the period from 1994 to 2004]

scientific article published on 01 March 2007

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