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List of works by Carmen Valenzuela

A new KCNQ1 mutation at the S5 segment that impairs its association with KCNE1 is responsible for short QT syndrome.

scientific article published on 13 July 2015

Activating transcription factor 6 derepression mediates neuroprotection in Huntington disease.

scientific article published on 11 January 2016

Activation of Kv 7 channels as a novel mechanism for NO/cGMP-induced pulmonary vasodilation

scientific article published on 11 May 2019

Assembly with the Kvbeta1.3 subunit modulates drug block of hKv1.5 channels

scientific article published in December 2002

Benzocaine enhances and inhibits the K+ current through a human cardiac cloned channel (Kv1.5).

scientific article published in May 1999

Block of human cardiac Kv1.5 channels by loratadine: voltage-, time- and use-dependent block at concentrations above therapeutic levels

scientific article published on August 1997

Blockade of cardiac potassium and other channels by antihistamines

scientific article

Bupivacaine effects on hKv1.5 channels are dependent on extracellular pH

scientific article

Celecoxib blocks cardiac Kv1.5, Kv4.3 and Kv7.1 (KCNQ1) channels: effects on cardiac action potentials

scientific article published on 18 September 2010

Cell cycle-dependent expression of Kv1.5 is involved in myoblast proliferation

scientific journal article

Ceramide inhibits Kv currents and contributes to TP-receptor-induced vasoconstriction in rat and human pulmonary arteries

scientific article published on 13 April 2011

Comparative effects of nonsedating histamine H1 receptor antagonists, ebastine and terfenadine, on human Kv1.5 channels

scientific article published on May 1997

Corrigendum to Supplemental Material: 'D242N, a KV7.1 LQTS mutation uncovers a key residue for IKs voltage dependence' [Journal of Molecular and Cellular Cardiology, Volume 110, September 2017, Pages 61-69]

scientific article published on 22 January 2019

D242N, a KV7.1 LQTS mutation uncovers a key residue for IKs voltage dependence.

scientific article

Differential effect of Androctonus australis hector venom components on macrophage KV channels: electrophysiological characterization

scientific article published on 13 July 2018

Differential regulation of Na(v)beta subunits during myogenesis

scientific article published on 7 February 2008

Effect of descarboethoxyloratadine, the major metabolite of loratadine, on the human cardiac potassium channel Kv1.5.

scientific article

Effects of a quaternary bupivacaine derivative on delayed rectifier K(+) currents

scientific article published in May 2000

Effects of irbesartan on cloned potassium channels involved in human cardiac repolarization

scientific article published in February 2003

Effects of levobupivacaine, ropivacaine and bupivacaine on HERG channels: stereoselective bupivacaine block

scientific article published on December 2002

Effects of lisinopril on cardiac contractility and ionic currents

scientific article published on September 1994

Effects of lisinopril on electromechanical properties and membrane currents in guinea‐pig cardiac preparations

scientific article published on July 1, 1993

Effects of n−3 Polyunsaturated Fatty Acids on Cardiac Ion Channels

scientific article published on July 9, 2012

Effects of propafenone and 5-hydroxy-propafenone on hKv1.5 channels

scientific article

Effects of propafenone and its main metabolite, 5-hydroxypropafenone, on HERG channels

scientific article published in March 2003

Effects of ropivacaine on a potassium channel (hKv1.5) cloned from human ventricle

scientific article published in March 1997

Effects of rupatadine, a new dual antagonist of histamine and platelet-activating factor receptors, on human cardiac kv1.5 channels

scientific article

Electrophysiologic Interactions Between Mexiletine-Quinidine and Mexiletine-Ropitoin in Guinea Pig Papillary Muscle

scientific article published on 01 November 1989

Electrophysiologic interactions between mexiletine and propafenone in guinea pig papillary muscles

scientific article published in September 1989

Electrophysiological Effects of 5-Hydroxypropafenone on Guinea Pig Ventricular Muscle Fibres

Electrophysiological effects of CI-980, a tubulin binding agent, on guinea-pig papillary muscles.

scientific article

Electrophysiological effects of CRE-1087 in guinea-pig ventricular muscles

scientific article published on October 1, 1992

Elisidepsin Interacts Directly with Glycosylceramides in the Plasma Membrane of Tumor Cells to Induce Necrotic Cell Death

scientific article

Female gender: risk factor for congenital long QT-related arrhythmias

scientific article published on June 21, 2012

Fludarabine Inhibits KV1.3 Currents in Human B Lymphocytes

scientific article published on 31 March 2017

Functional assembly of Kv7.1/Kv7.5 channels with emerging properties on vascular muscle physiology

scientific article

Functional expression of an inactivating potassium channel (Kv4.3) in a mammalian cell line

scientific article published on January 1999

Gating of cardiac Na+ channels in excised membrane patches after modification by alpha-chymotrypsin

scientific article

Identification of IQM-266, a Novel DREAM Ligand That Modulates KV4 Currents

scientific article published on 04 February 2019

Immunomodulation of voltage-dependent K+ channels in macrophages: molecular and biophysical consequences

scientific article

Immunomodulatory effects of diclofenac in leukocytes through the targeting of Kv1.3 voltage-dependent potassium channels

scientific article published on 19 May 2010

In-Depth Study of the Interaction, Sensitivity, and Gating Modulation by PUFAs on K+ Channels; Interaction and New Targets

scientific article

Interaction of angiotensin II with the angiotensin type 2 receptor inhibits the cardiac transient outward potassium current

scientific article published in April 2004

Irvalec inserts into the plasma membrane causing rapid loss of integrity and necrotic cell death in tumor cells

scientific article (publication date: 2011)

Kvbeta1.3 reduces the degree of stereoselective bupivacaine block of Kv1.5 channels

scientific article

M-channels and n-3 polyunsaturated fatty acids: role in pain and epilepsy.

scientific article published on 25 June 2016

Marine n-3 PUFAs modulate IKs gating, channel expression, and location in membrane microdomains.

scientific article

Modulation of the atrial specific Kv1.5 channel by the n-3 polyunsaturated fatty acid, alpha-linolenic acid

scientific article published on 22 November 2007

Modulation of voltage-dependent and inward rectifier potassium channels by 15-epi-lipoxin-A4 in activated murine macrophages: implications in innate immunity.

scientific article published on 18 November 2013

PKC inhibition results in a Kv 1.5 + Kv β1.3 pharmacology closer to Kv 1.5 channels.

scientific article published on 5 September 2014

Pharmacological electrical remodelling in human atria induced by chronic β-blockade

scientific article published on 01 June 2003

Pharmacology of CRE-1087, A New Antiarrhythmic Drug

scholarly article by Eva Delpón et al published September 1992 in Cardiovascular Drug Reviews

Pharmacology of cardiac potassium channels.

scientific article published on April 2004

Polyunsaturated Fatty acids modify the gating of kv channels

scientific article published on 10 September 2012

Protein kinase C (PKC) activity regulates functional effects of Kvβ1.3 subunit on KV1.5 channels: identification of a cardiac Kv1.5 channelosome

scientific article published on 30 April 2012

Putative binding sites for benzocaine on a human cardiac cloned channel (Kv1.5).

scientific article published on October 2002

Spironolactone and its main metabolite, canrenoic acid, block human ether-a-go-go-related gene channels

scientific article published in February 2003

Stereoselective Interactions Between Local Anesthetics and Cardiac K+ Channels

Stereoselective block of a human cardiac potassium channel (Kv1.5) by bupivacaine enantiomers

scientific article

Stereoselective effects of the enantiomers of a new local anaesthetic, IQB-9302, on a human cardiac potassium channel (Kv1.5)

scientific article

Stereoselective interactions between local anesthetics and ion channels.

scientific article published on 07 June 2012

Targeting the neuronal calcium sensor DREAM with small-molecules for Huntington's disease treatment

scientific article published on 13 May 2019

The induction of NOS2 expression by the hybrid cecropin A-melittin antibiotic peptide CA(1-8)M(1-18) in the monocytic line RAW 264.7 is triggered by a temporary and reversible plasma membrane permeation

scientific article published on 9 December 2005

The unconventional biogenesis of Kv7.1-KCNE1 complexes

scientific article published on 01 April 2020

Tonic and Phasic Vmax Block Induced by 5-Hydroxypropafenone in Guinea Pig Ventricular Muscles

scientific article published on 01 October 1988

Tonic and frequency-dependent $$\mathop {\text{V}}\limits^{\text{.}} _{{\text{max}}} $$ block induced by (S)-nafenodone, a new antidepressant drug, in guinea-pig papillary muscles

Tonic and frequency-dependent Vmax block induced by imipramine in guinea pig ventricular muscle fibers

scientific article

Ultrafast sodium channel block by dietary fish oil prevents dofetilide-induced ventricular arrhythmias in rabbit hearts

scientific article

Voltage- and use-dependent modulation of calcium channel current in guinea pig ventricular cells by amiodarone and des-oxo-amiodarone

scientific article published on June 1991

Voltage-dependent Na+ channel phenotype changes in myoblasts. Consequences for cardiac repair.

scientific article

{Omega}-3 and {omega}-6 polyunsaturated fatty acids block HERG channels

scientific article published on 29 June 2005