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List of works by Erwin F. Wagner

5-Methylcytosine content of DNA during differentiation in mouse teratocarcinoma cells

scientific article published on 01 November 1979

A FATal AP-1 dimer switch in hepatosteatosis

scientific article

A central role for the JNK pathway in mediating the antagonistic activity of pro-inflammatory cytokines against transforming growth factor-beta-driven SMAD3/4-specific gene expression.

scientific article published on 7 November 2002

A miR-34a-SIRT6 axis in the squamous cell differentiation network

scientific article published on 16 July 2013

A novel ATP-driven glucose transport system in Escherichia coli

scientific article published on December 1979

A novel target cell for c-fos-induced oncogenesis: development of chondrogenic tumours in embryonic stem cell chimeras ⬇️

scientific article published on September 1, 1991

A putative role for c-Fos in the pathophysiology of Paget's disease.

scientific article

A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor

scientific article

A switch from white to brown fat increases energy expenditure in cancer-associated cachexia

scientific article published on 17 July 2014

A universal retroviral vector for efficient constitutive expression of exogenous genes

scientific article

A validated regulatory network for Th17 cell specification

scientific journal article

AP-1 dimers regulate transcription of the p14/p19ARF tumor suppressor gene

scientific article published in March 2005

AP-1 in mouse development and tumorigenesis

scientific article

AP-1 mediated retinal photoreceptor apoptosis is independent of N-terminal phosphorylation of c-Jun

scientific article published in August 2001

AP-1--Introductory remarks

scientific article (publication date: 30 April 2001)

AP-1: a double-edged sword in tumorigenesis

scientific article (publication date: November 2003)

Acquisition of an immunosuppressive protumorigenic macrophage phenotype depending on c-Jun phosphorylation

scientific article

Activated Fps/Fes partially rescues the in vivo developmental potential of Flk1-deficient vascular progenitor cells

scientific article published on 2 October 2003

Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways

scientific article published on March 2003

Activation of HIV transcription by human foamy virus in transgenic mice.

scientific article

Activator Protein 1 transcription factor Fos-related antigen 1 (Fra-1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism.

scientific article published on 10 October 2013

Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease

scientific article published on 18 January 2008

Amino-terminal phosphorylation of c-Jun regulates apoptosis in the retinal ganglion cells by optic nerve transection

scientific article published in May 2002

Analysis of the differentiation-promoting potential of inducible c-fos genes introduced into embryonal carcinoma cells

scientific article published on July 1985

Antagonistic control of cell fates by JNK and p38-MAPK signaling.

scientific article published on 31 August 2007

Anti-oncogenic activity of signalling-defective epidermal growth factor receptor mutants

scientific article published on February 1992

Autoamplification of NFATc1 expression determines its essential role in bone homeostasis

scientific article published on November 2005

BCR/ABL promotes dendritic cell-mediated natural killer cell activation

scientific article published in July 2005

Bone and haematopoietic defects in mice lacking c-fos

scientific article published in Nature

Bone development and inflammatory disease is regulated by AP-1 (Fos/Jun).

scientific article published on January 2010

C-jun inhibits mammary apoptosis in vivo

scientific article

CD44 is a determinant of inflammatory bone loss

scientific article

CD44 regulates bone erosion and osteoclastogenesis in arthritis.

scientific article

CXCL5 Facilitates Melanoma Cell-Neutrophil Interaction and Lymph Node Metastasis

scientific article published on 20 February 2018

Cancer metabolism: A waste of insulin interference

scientific article published in May 2015

Cancer: Fibroblasts for all seasons.

scientific article

Catecholamine synthesizing enzymes and their modulation by immobilization stress in knockout mice

scientific article published in June 2004

Cell differentiation

Cell proliferation and cell cycle progression are not impaired in fibroblasts and ES cells lacking c-Fos.

scientific article published on January 1995

Characterization of fos-induced osteogenic tumours and tumour-derived murine cell lines

scientific article published on August 1990

Characterization of mouse model-derived osteosarcoma (OS) cells in vitro and in vivo.

scientific article

Chronic Myeloid Leukemia with Increased Granulocyte Progenitors in Mice Lacking JunB Expression in the Myeloid Lineage

scientific article published on 01 January 2001

Chronic inflammation imposes aberrant cell fate in regenerating epithelia through mechanotransduction.

scientific article published on 21 December 2015

Chronic skin inflammation leads to bone loss by IL-17-mediated inhibition of Wnt signaling in osteoblasts

scientific article

Chronic systemic inflammation originating from epithelial tissues.

scientific article published on 21 September 2016

Clustered homeo boxes are differentially expressed during murine development

scientific article published in November 1985

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

scientific article published on 01 December 1994

Conditional inactivation of VEGF-A in areas of collagen2a1 expression results in embryonic lethality in the heterozygous state.

scientific article published in April 2000

Control of cell cycle progression by c-Jun is p53 dependent

scientific article

Control of phosphoenolpyruvate-dependent phosphotransferase-mediated sugar transport in Escherichia coli by energization of the cell membrane

scientific article

Correction: Mice humanised for the EGF receptor display hypomorphic phenotypes in skin, bone and heart

scientific article published in December 2016

Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling

scientific article published in October 2003

Defective angiogenesis delays thrombus resolution: a potential pathogenetic mechanism underlying chronic thromboembolic pulmonary hypertension

scientific article published on 13 February 2014

Defective induction but normal activation and function of p53 in mouse cells lacking poly-ADP-ribose polymerase

scientific article published on August 1997

Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase

scientific article

Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2.

scientific article

Deficiency of DNA ligase activity in Fanconi's anemia

scientific article published on 01 November 1978

Degeneration of neural cells in the central nervous system of mice deficient in the gene for the adhesion molecule on Glia, the beta 2 subunit of murine Na,K-ATPase

scientific article published on November 1994

Deregulated c-fos expression interferes with normal bone development in transgenic mice

scientific article published in Nature

Development of E.coli virus T1: the pattern of gene expression

scientific article published on January 1977

Development of Escherichia coli virus T1. The role of the proton-motive force

scientific article

Development of Escherichia coli virus T1: escape from host restriction

scientific article published on March 1979

Development of Escherichia coli virus T1: repression of host gene expression

scientific article

Development of a lethal mast cell disease in mice reconstituted with bone marrow cells expressing the v-erbB oncogene

article

Development of escherichia coli virus T1. ATP-mediated discrimination of gene expression.

scientific article published in January 1980

Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1.

scholarly article

Differential effects of JNK1 and JNK2 on signal specific induction of apoptosis

scientific article published on April 2002

Differential utilization and localization of ErbB receptor tyrosine kinases in skin compared to normal and malignant keratinocytes

scientific article

Differentiation of F9 teratocarcinoma stem cells after transfer of c-fos proto-oncogenes

scientific article published in Nature

Differentiation-induced skin cancer suppression by FOS, p53, and TACE/ADAM17.

scientific article

Directed differentiation of hematopoietic precursors and functional osteoclasts from human ES and iPS cells

scientific article

Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase

scientific article

Distinct functions of junD in cardiac hypertrophy and heart failure

scientific article

Distinct involvement of the Jun-N-terminal kinase and NF-kappaB pathways in the repression of the human COL1A2 gene by TNF-alpha.

scientific article published on 22 October 2002

Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon

scientific article published in April 1999

Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation

scientific article published on September 2004

Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal.

scientific article

EGFR controls bone development by negatively regulating mTOR-signaling during osteoblast differentiation.

scientific article published on 14 February 2018

EGFR is required for FOS-dependent bone tumor development via RSK2/CREB signaling

scientific article published on 01 November 2018

EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer

scientific article published on 06 July 2008

EMBO medal review. On transferring genes into stem cells and mice.

scientific article

Early fetal hematopoietic development from in vitro differentiated embryonic stem cells

scientific article published on July 1, 1991

Editorial Overview: The ins and outs of stem cells in differentiation, inflammation & disease

scientific article published in December 2016

Efficient adult skeletal muscle regeneration in mice deficient in p38beta, p38gamma and p38delta MAP kinases

scientific article published on 12 May 2008

Efficient keratinocyte differentiation strictly depends on JNK-induced soluble factors in fibroblasts

scientific article published on 16 November 2013

Elevated Fra-1 expression causes severe lipodystrophy

scientific article published on 12 April 2011

Embryonic lethalities and endothelial tumors in chimeric mice expressing polyoma virus middle T oncogene

scientific article

Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene

scientific article published on April 2001

Embryonic overexpression of the c-Fos protooncogene. A murine stem cell chimera applicable to the study of fibrodysplasia ossificans progressiva in humans

scientific article published on January 1998

Embryonic stem (ES) cells lacking functional c-jun: consequences for growth and differentiation, AP-1 activity and tumorigenicity

scientific article published on December 1992

Endothelial cell transformation by polyomavirus middle T antigen in mice lacking Src-related kinases.

scientific article published on February 1994

Endothelioma cells expressing the polyoma middle T oncogene induce hemangiomas by host cell recruitment

scientific article published on June 1989

Epidermal JunB represses G-CSF transcription and affects haematopoiesis and bone formation

scientific article published on 20 July 2008

Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signaling.

scientific article

Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress.

scientific article

Erratum: Corrigendum: Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins

scientific article published in Nature

Erratum: c-Jun is essential for normal mouse development and hepatogenesis

scientific article published in Nature

Escherichia coli virus T1: genetic controls during virus infection

scientific article published on January 1983

Essential role of RSK2 in c-Fos-dependent osteosarcoma development

scientific article

Essential role of the keratinocyte-specific endonuclease DNase1L2 in the removal of nuclear DNA from hair and nails

scientific journal article

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

scientific article

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

scientific article (publication date: 11 September 2011)

Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors.

scientific article published in November 1985

Expression of c-src and c-abl in embryonal carcinoma cells and adult mouse tissues

scientific article published in November 1988

Expression of collagenase-3 (MMP-13) in c-Fos-induced osteosarcomas and chondrosarcomas is restricted to a subset of cells of the osteo-/chondrogenic lineage

Expression of foreign genes from retroviral vectors in mouse teratocarcinoma chimaeras.

scientific article

Expression of functional c-kit receptors rescues the genetic defect of W mutant mast cells ⬇️

scientific article published on December 1, 1991

Expression of human CSF-1 receptor induces CSF-1-dependent proliferation in murine myeloid but not in T-lymphoid cells

scientific article published on January 1991

Expression of human alpha 1-acid glycoprotein genes in cultured cells and in transgenic mice ⬇️

scientific article published on February 1, 1988

Expression of human foamy virus is differentially regulated during development in transgenic mice

scientific article published on March 1992

Expression of interstitial collagenase during skeletal development of the mouse is restricted to osteoblast-like cells and hypertrophic chondrocytes

article

Expression of retroviral vectors in transgenic mice obtained by embryo infection

scientific article

Expression of v-src arrests murine glial cell differentiation.

scientific article published in April 1989

Expression of v-src induces a myeloproliferative disease in bone-marrow-reconstituted mice

scientific article published on 01 June 1989

Expression of v-src induces aberrant development and twinning in chimaeric mice

scientific article published on February 1991

FOSL1 controls the assembly of endothelial cells into capillary tubes by direct repression of αv and β3 integrin transcription

scientific article

FOSL2 promotes leptin gene expression in human and mouse adipocytes

scientific article published on 13 February 2012

Factor-dependent erythroid cell lines derived from mice transplanted with hematopoietic cells expressing the v-src oncogene

scientific article published on January 1992

Formation of transformed endothelial cells in the absence of VEGFR-2/Flk-1 by Polyoma middle T oncogene.

scientific article published in July 1999

Fos Proteins Suppress Dextran Sulfate Sodium-Induced Colitis through Inhibition of NF- B

scientific article published on 16 December 2009

Fos and bone cell development: lessons from a nuclear oncogene

scientific article published on November 1995

Fos and jun proteins are specifically expressed during differentiation of human keratinocytes

scientific article published on January 2005

Fos is an essential component of the mammalian UV response

scientific article

Fos-dependent induction of Chk1 protects osteoblasts from replication stress

scientific article

Fos/AP-1 proteins in bone and the immune system

scientific article

Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation

Fra-1 potentiates osteoclastic differentiation in osteoclast-macrophage precursor cell lines

scientific article published on May 1999

Fra-1 replaces c-Fos-dependent functions in mice

scientific article

Fra-1 substitutes for c-Fos in AP-1-mediated signal transduction in retinal apoptosis

scientific article published in March 2002

Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression

scientific article

Fra-2 Expression in Osteoblasts Regulates Systemic Inflammation and Lung Injury through Osteopontin

scholarly article by Yubin Luo published in November 2018

Fra-2 negatively regulates postnatal alveolar septation by modulating myofibroblast function.

scientific article published on 17 August 2017

Fra-2/AP-1 controls adipocyte differentiation and survival by regulating PPARγ and hypoxia

scientific article published on 24 January 2014

Fra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production ⬇️

scientific article

Function of Fos proteins in bone cell differentiation

scientific article published on 01 July 1999

Functions of AP1 (Fos/Jun) in bone development

scientific article

Functions of Fos phosphorylation in bone homeostasis, cytokine response and tumourigenesis

scientific article

Gene Transfer Into the Germ Line of Mice and Into Embryonal Carcinoma Stem Cells

article

Gene transfer into murine stem cells and mice using retroviral vectors.

scientific article

Generation of completely embryonic stem cell-derived mutant mice using tetraploid blastocyst injection

scientific article published in March 1997

Generation of high-titer retroviral vectors following receptor-mediated, adenovirus-augmented transfection.

scientific article published on March 1995

Generation of normal T and B lymphocytes by c-jun deficient embryonic stem cells

scientific article published on 01 April 1994

Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation

scientific article published on 15 February 2007

Genetic control of skeletal development

article

Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis

article published in 1997

Hepatocyte survival in acute hepatitis is due to c-Jun/AP-1-dependent expression of inducible nitric oxide synthase

scholarly article

Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis

scientific journal article

Human beta-globin gene sequences injected into mouse eggs, retained in adults, and transmitted to progeny

scientific article published in Science

Human foamy virus proteins accumulate in neurons and induce multinucleated giant cells in the brain of transgenic mice

scientific article published on April 1993

IL-4 confers NK stimulatory capacity to murine dendritic cells: a signaling pathway involving KARAP/DAP12-triggering receptor expressed on myeloid cell 2 molecules

scientific article published in May 2004

Identification of the human homolog of the imprinted mouse Air non-coding RNA.

scientific article

Impaired Wnt signaling in embryonal rhabdomyosarcoma cells from p53/c-fos double mutant mice

scientific article

Impaired intervertebral disc formation in the absence of Jun.

scientific article published in January 2003

Impaired long-term memory and NR2A-type NMDA receptor-dependent synaptic plasticity in mice lacking c-Fos in the CNS.

scientific article published in October 2003

Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver

scientific article

Imprinted expression of the Igf2r gene depends on an intronic CpG island

scientific article published in October 1997

Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells.

scientific article published in May 1995

Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1

article by Wolfram Jochum et al published September 2000 in Nature Medicine

Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene

scientific article published on August 1990

Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts

scientific article (publication date: December 2002)

Induction of DNA synthesis in primary mouse hepatocytes is associated with nuclear pro-transforming growth factor alpha and erbb-1 and is independent of c-jun

scientific article published on May 2003

Induction of tumor formation and cell transformation by polyoma middle T antigen in the absence of Src.

scientific article published in September 1993

Infarct volume after transient middle cerebral artery occlusion (MCAo) can be reduced by attenuation but not by inactivation of c-Jun action

scientific article

Inflammation-mediated skin tumorigenesis induced by epidermal c-Fos

scientific article

Inhibition of de novo NAD(+) synthesis by oncogenic URI causes liver tumorigenesis through DNA damage

scientific article

Interstitial lung disease induced by gefitinib and Toll-like receptor ligands is mediated by Fra-1

scientific article published on 04 April 2011

Intramedullary and extramedullary B lymphopoiesis in osteopetrotic mice.

scientific article published in June 2000

Introduction of a selectable gene into murine T-lymphoblasts by a retroviral vector.

scientific article published in May 1986

Introduction of a viral thymidine kinase gene and the human beta-globin gene into developmentally multipotential mouse teratocarcinoma cells

scientific article

Is the DNA of virus T7 methylated?

scientific article published on September 1979

I{kappa}B kinase (IKK){beta}, but not IKK{alpha}, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss

scientific article

JNK phosphorylation relieves HDAC3-dependent suppression of the transcriptional activity of c-Jun

scientific article published on July 2003

JNK1 is not essential for TNF-mediated joint disease

scientific article

JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanisms

scientific article published on 01 November 2002

JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development.

scientific article

JNK2: a negative regulator of cellular proliferation

scientific article

JUNB/AP-1 controls IFN-γ during inflammatory liver disease

scientific article

Jun N-terminal kinase 2 modulates thymocyte apoptosis and T cell activation through c-Jun and nuclear factor of activated T cell (NF-AT)

scientific article

Jun and JunD-dependent functions in cell proliferation and stress response.

scientific article published on 19 March 2010

Jun signalling in the epidermis: From developmental defects to psoriasis and skin tumors

scientific article

JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells

scientific article

JunB can substitute for Jun in mouse development and cell proliferation

scientific journal article

JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells

scientific article published in October 2004

JunB inhibits proliferation and transformation in B-lymphoid cells.

scientific article

JunB is a gatekeeper for B-lymphoid leukemia

scientific article published on 12 February 2007

JunB is a key regulator of multiple myeloma bone marrow angiogenesis

scientific article published on 18 May 2021

JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression

scientific article

JunD regulates lymphocyte proliferation and T helper cell cytokine expression

scientific article

JunD suppresses bone formation and contributes to low bone mass induced by estrogen depletion

scholarly article by Aya Kawamata published in January 2008

Lesion-induced increase in nerve growth factor mRNA is mediated by c-fos

scientific article

Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin.

scientific article

Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation

scientific article published on 29 March 2017

Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53

scientific article (publication date: 24 January 2003)

Localization of regulatory elements controlling human MYCN expression

scientific article published on June 1991

Loss of JUNB/AP-1 promotes invasive prostate cancer

scientific article

Loss of vascular endothelial growth factor a activity in murine epidermal keratinocytes delays wound healing and inhibits tumor formation

scientific article

MKK7 couples stress signalling to G2/M cell-cycle progression and cellular senescence.

scientific article published on 22 February 2004

Mechanisms of metabolic dysfunction in cancer-associated cachexia

scientific article

Mice humanised for the EGF receptor display hypomorphic phenotypes in skin, bone and heart

scientific article

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease ⬇️

scientific article published on March 1, 1995

Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects

scientific journal article

Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects

scientific article published in December 2011

Mice lacking c-fos have normal hematopoietic stem cells but exhibit altered B-cell differentiation due to an impaired bone marrow environment

scientific article published in January 1994

Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin

scientific article published in March 1999

Mice with a fra-1 knock-in into the c-fos locus show impaired spatial but regular contextual learning and normal LTP.

scientific article

Mitogen-inducible gene-6 is a negative regulator of epidermal growth factor receptor signaling in hepatocytes and human hepatocellular carcinoma

scientific article

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

scientific article

Mouse genetics meets molecular biology at Cold Spring Harbor. Mouse Molecular Genetics sponsored by the Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA, August 29-September 2, 1990.

scientific article published in December 1990

Mouse models for liver cancer ⬇️

scientific article published on 05 February 2013

NF-κB p50 and p52 Regulate Receptor Activator of NF-κB Ligand (RANKL) and Tumor Necrosis Factor-induced Osteoclast Precursor Differentiation by Activating c-Fos and NFATc1

scientific article published in Journal of Biological Chemistry

Neuronal survival depends on EGFR signaling in cortical but not midbrain astrocytes

scientific article

News and views on EMT Fra-1 controls EMT in mammary epithelial cells.

scientific article published on 23 January 2015

Non-imprinted Igf2r expression decreases growth and rescues the Tme mutation in mice.

scientific article published in May 2001

Normal mineralization and nanostructure of sclerotic bone in mice overexpressing Fra-1.

scientific article published in May 2004

Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos

scientific article

Of kit and mouse and man

scientific article published on 01 December 1991

On the biological role of the nuclear polymerizing NAD+: protein(ADP-ribosyl) transferase (ADPRT): ADPRT from Dictyostelium discoideum and inactivation of the ADPRT gene in the mouse

scientific article published on January 1995

Oncogenes in the study of endothelial cell growth and differentiation.

scientific article

Oncogenic properties of the middle T antigens of polyomaviruses.

scientific article published on January 1994

Oncogenic transformation by ras and fos is mediated by c-Jun N-terminal phosphorylation

scientific article (publication date: 18 May 2000)

Opposing Roles of JNK and p38 in Lymphangiogenesis in Melanoma.

scientific article published on 29 January 2016

Osteoblast-specific expression of Fra-2/AP-1 controls adiponectin and osteocalcin expression and affects metabolism

scientific article published on 17 September 2013

Osteoblasts are target cells for transformation in c-fos transgenic mice

scientific article published on August 1993

Osteoclast lineage commitment of bone marrow precursors through expression of membrane-bound TRANCE.

scientific article published in July 2000

Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia

scientific article published on 11 June 2008

Osteoclasts are essential for TNF-alpha-mediated joint destruction

scientific article

Osteogenic capillaries orchestrate growth plate-independent ossification of the malleus.

scientific article

PARP is important for genomic stability but dispensable in apoptosis

scientific article

Pancreatic β-cells activate a JunB/ATF3-dependent survival pathway during inflammation

scientific article published on 15 August 2011

Pharmacological activation of LXR alters the expression profile of tumor-associated macrophages and the abundance of regulatory T cells in the tumor microenvironment

scientific article published on 23 December 2020

Phosphate-dependent regulation of MGP in osteoblasts: role of ERK1/2 and Fra-1.

scientific article published on November 2009

Podoplanin is a novel fos target gene in skin carcinogenesis

scientific article published in September 2008

Polyoma middle T-induced vascular tumor formation: the role of the plasminogen activator/plasmin system

scientific article

Prenatal lethalities in mice homozygous for human growth hormone gene sequences integrated in the germ line

scientific article published in December 1983

Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation

scientific article published on 6 November 2008

Promoter specificity and biological activity of tethered AP-1 dimers

scientific article

Protective role of Raf-1 in Salmonella-induced macrophage apoptosis

scientific article published on February 2001

Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins

scientific article

Psoriasis: what we have learned from mouse models

scientific article published on 28 September 2010

RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β

scientific article published in Nature

Radiation sensitivity of messenger RNA.

scientific article published on August 1979

Reaching a genetic and molecular understanding of skeletal development

scientific article

Regulation of ES cell differentiation by functional and conformational modulation of p53.

scientific article published on October 1997

Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene

scientific article published on December 1994

Regulation of steatohepatitis and PPARγ signaling by distinct AP-1 dimers

scientific article

Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis

scientific article published in November 2004

Rescue of W-associated mast cell defects in W/Wv bone marrow cells by ectopic expression of normal and mutant epidermal growth factor receptors

scientific article published on 01 September 1993

Rhabdomyosarcoma development in mice lacking Trp53 and Fos

article

Rheumatoid arthritis therapy after tumor necrosis factor and interleukin-1 blockade

scientific article published on December 2003

Role of IL-17A signalling in psoriasis and associated bone loss

scientific article

Role of bulge epidermal stem cells and TSLP signaling in psoriasis

scientific article published on 26 September 2019

Role of heterodimerization of c-Fos and Fra1 proteins in osteoclast differentiation

article

Role of the ATFa/JNK2 complex in Jun activation

scientific article

S100A8-S100A9 protein complex mediates psoriasis by regulating the expression of complement factor C3.

scientific article

Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells

scientific article published on May 1986

Signal integration by JNK and p38 MAPK pathways in cancer development

scientific article published on August 2009

Signalling in inflammatory skin disease by AP-1 (Fos/Jun).

scientific article published on 12 October 2015

Signalling in osteoclasts and the role of Fos/AP1 proteins ⬇️

scientific article published on November 1, 2003

Simultaneous generation offra-2 conditional andfra-2 knock-out mice

article

Somatic excision demonstrates that c-Jun induces cellular migration and invasion through induction of stem cell factor

scientific article published on 4 December 2006

Specific pathophysiological functions of JNK isoforms in the brain

scientific article published in January 2005

Specific roles for dendritic cell subsets during initiation and progression of psoriasis

scientific article

Stable murine chondrogenic cell lines derived from c-fos-induced cartilage tumors

Stat5 tetramer formation is associated with leukemogenesis

scientific article published on 01 January 2005

Strain-dependent epithelial defects in mice lacking the EGF receptor

scientific article

Sympathetic hyperplasia and neuroblastomas in transgenic mice expressing polyoma middle T antigen

scientific article published in June 1990

Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis

scientific article published on 07 December 2009

TNFalpha shedding and epidermal inflammation are controlled by Jun proteins

scientific article published on November 2009

Targeting c-Jun and JunB proteins as potential anticancer cell therapy

scientific article (publication date: 24 January 2008)

Targeting inflammation by modulating the Jun/AP-1 pathway

scientific article published on March 2011

Targeting miR-21 to Treat Psoriasis

scientific article published on 01 February 2014

Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2

scientific journal article

The AP-1 transcription factor Fra1 inhibits follicular B cell differentiation into plasma cells

scientific article

The AP-1 transcription factor Fra1 inhibits follicular B cell differentiation into plasma cells

The AP-1 transcription factor JunB is essential for multiple myeloma cell proliferation and drug resistance in the bone marrow microenvironment.

scientific article published on 28 November 2016

The AP-1 transcription factor c-Jun is required for efficient axonal regeneration

scientific journal article

The AP-1 transcription factor c-Jun prevents stress-imposed maladaptive remodeling of the heart

scientific article

The AP-1 transcription factors c-Jun and JunB are essential for CD8α conventional dendritic cell identity

scientific article published on 23 March 2021

The AP1 transcription factor Fra2 is required for efficient cartilage development.

scientific article published in November 2004

The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development

scientific article

The European dimension for the mouse genome mutagenesis program

scientific article

The Fos-related antigen Fra-1 is an activator of bone matrix formation

scientific article

The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo

scientific article published on 01 March 1997

The c-Jun N-terminal kinases in cerebral microglia: immunological functions in the brain

scientific article

The expression of retroviral vectors in murine stem cells and transgenic mice

scientific article published on 01 October 1986

The human alpha-1-antitrypsin gene is efficiently expressed from two tissue-specific promotors in transgenic mice

scientific article

The human beta-globin gene and a functional viral thymidine kinase gene in developing mice.

scientific article

The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice

scientific article published on May 1996

The limited role of NH2-terminal c-Jun phosphorylation in neuronal apoptosis: identification of the nuclear pore complex as a potential target of the JNK pathway.

scientific article

The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest

scientific article

The molecular clock mediates leptin-regulated bone formation

scientific article published in September 2005

The origins of oncomice: a history of the first transgenic mice genetically engineered to develop cancer

scientific article

The role of the transcription factor AP-1 in colitis-associated and β-catenin-dependent intestinal tumorigenesis in mice

scientific article published on 04 August 2008

The transcription factor c-JUN/AP-1 promotes HBV-related liver tumorigenesis in mice

scientific article published on 16 October 2015

Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas.

scientific article published on 14 February 2018

Transcriptional regulation of EGR-1 by the interleukin-1-JNK-MKK7-c-Jun pathway

scientific article published on 15 February 2008

Transfer of Nonselectable Genes into Mouse Teratocarcinoma Cells and Transcription of the Transferred Human β-Globin Gene ⬇️

scientific article published on February 1, 1982

Transfer of genes into embryonal carcinoma cells by retrovirus infection: efficient expression from an internal promoter

scientific article published on March 1985

Transgenic activation of Ras in neurons promotes hypertrophy and protects from lesion-induced degeneration

scientific article published on December 2000

Transgenic animals

Tumour induction in fetal brain transplants exposed to the viral oncogenes polyoma middle T and v-src.

scientific article published in January 1989

Virus Delivery of CRISPR Guides to the Murine Prostate for Gene Alteration

article

When flies and mice develop cancer. Meeting on development and cancer

scientific article published on 18 July 2008

Wnt signaling and Loxl2 promote aggressive osteosarcoma

scientific article published on 20 July 2020

[Loss of junB expression causes a myeloproliferative syndrome resembling chronic myeloid leukemia]

scientific article published on 01 January 1999

c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling

scientific article

c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation

scientific article

c-Jun controls histone modifications, NF-kappaB recruitment, and RNA polymerase II function to activate the ccl2 gene

scientific article published on 28 April 2008

c-Jun is essential for normal mouse development and hepatogenesis

scientific article published in Nature

c-Jun regulates eyelid closure and skin tumor development through EGFR signaling

scientific article published on June 2003

c-Jun/AP-1 controls liver regeneration by repressing p53/p21 and p38 MAPK activity

scientific article

c-fos expression induces bone tumors in transgenic mice

scientific article published on 01 July 1989

c-fos expression interferes with thymus development in transgenic mice.

scientific article

c-fos-induced osteosarcoma formation in transgenic mice: cooperativity with c-jun and the role of endogenous c-fos

scientific article published on 01 December 1995

p38alpha: a suppressor of cell proliferation and tumorigenesis

scientific article published on 21 October 2007

p38α controls erythroblast enucleation and Rb signaling in stress erythropoiesis

scientific article published on 27 September 2011

p38α suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway

article by Lijian Hui et al published 29 April 2007 in Nature Genetics

recessive spotting: a linked locus that interacts with W/Kit but is not allelic

scientific article published on April 1998

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