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List of works by Neil A. Hanley

A novel immunomodulator, FTY-720 reverses existing cardiac hypertrophy and fibrosis from pressure overload by targeting NFAT (nuclear factor of activated T-cells) signaling and periostin

scientific article

A tissue-specific, Gata6-driven transcriptional program instructs remodeling of the mature arterial tree

scientific article published on 27 September 2017

Age-specific changes in sex steroid biosynthesis and sex development

scientific article published on September 2007

An integrative transcriptomic atlas of organogenesis in human embryos

scientific article published on 24 August 2016

Analysis of SOX2 expression in developing human testis and germ cell neoplasia

scientific article published on January 2010

Assessing the safety of stem cell therapeutics

scientific article published on June 2011

Beta cell differentiation during early human pancreas development

scientific article

Biocompatibility and osteogenic potential of human fetal femur-derived cells on surface selective laser sintered scaffolds

scientific article

Bone marrow-derived cells and the vasculature in diabetes: from biomarker to treatment?

scientific article published on 26 July 2007

Centriolar association of ALMS1 and likely centrosomal functions of the ALMS motif-containing proteins C10orf90 and KIAA1731

scientific article

Characterization and multipotentiality of human fetal femur-derived cells: implications for skeletal tissue regeneration

scientific article published on 22 December 2005

Chronological expression of Ciliated Bronchial Epithelium 1 during pulmonary development

scientific article

Closing in on pancreatic beta cells

scientific article published on 01 November 2014

Commonalities in the endocrinology of stem cell biology and organ regeneration.

scientific article published on 8 April 2008

Cushing's syndrome in women with polycystic ovaries and hyperandrogenism

scientific article published in November 2007

Deoxyribonucleic acid methylation controls cell type-specific expression of steroidogenic factor 1.

scientific article

Derivation of a novel undifferentiated human foetal phenotype in serum-free cultures with BMP-2.

scientific article

Development of the human pancreas from foregut to endocrine commitment.

scientific article published on 29 April 2013

Dynamic changes in the epigenomic landscape regulate human organogenesis and link to developmental disorders

scientific article published on 06 August 2020

Ectopic SOX9 mediates extracellular matrix deposition characteristic of organ fibrosis

scientific article

Embryonic stem cells to beta-cells by understanding pancreas development

scientific article published on 27 March 2008

Epimorphin alters the inhibitory effects of SOX9 on Mmp13 in activated hepatic stellate cells.

scientific article

Essential Endocrinology and Diabetes: Fifth Edition

scientific article published in August 2007

Evaluating Human Embryonic Germ Cells: Concord and Conflict as Pluripotent Stem Cells

scientific article

Expression of steroidogenic factor 1 and Wilms' tumour 1 during early human gonadal development and sex determination

scientific article published in September 1999

Expression profiles of SF-1, DAX1, and CYP17 in the human fetal adrenal gland: potential interactions in gene regulation

scientific article

Generating hepatic cell lineages from pluripotent stem cells for drug toxicity screening

scientific article published on 04 March 2010

Generation of Distal Airway Epithelium from Multipotent Human Foregut Stem Cells

scientific article published on 15 April 2015

Generation of multipotent foregut stem cells from human pluripotent stem cells

scientific article published on 10 October 2013

Genes, mice and the internet: is WT1 the shape of things to come?

scientific article published on 01 April 2000

Human embryo and early fetus research

scientific article published on August 2006

Human embryonic germ cells for future neuronal replacement therapy

scientific article

Human notochordal cell transcriptome unveils potential regulators of cell function in the developing intervertebral disc

scientific article published in Scientific Reports

Human pluripotent stem cells for modeling toxicity

scientific article published on January 2012

Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes

scientific article

Hypoxia inducible factors regulate pluripotency and proliferation in human embryonic stem cells cultured at reduced oxygen tensions

scientific article published on January 2010

Identification of a primitive intestinal transcription factor network shared between esophageal adenocarcinoma and its precancerous precursor state

scientific article published on 08 April 2019

In humans, early cortisol biosynthesis provides a mechanism to safeguard female sexual development

scientific article

In vitro expression of NGN3 identifies RAB3B as the predominant Ras-associated GTP-binding protein 3 family member in human islets

scientific article

Inactivating PAPSS2 mutations in a patient with premature pubarche

scientific article published in May 2009

Inactivation of Six2 in mouse identifies a novel genetic mechanism controlling development and growth of the cranial base

scientific journal article

Induction of a disintegrin and metalloprotease 33 during embryonic lung development and the influence of IL-13 or maternal allergy

scientific article

Insights into the molecular mechanism for type 2 diabetes susceptibility at the KCNQ1 locus from temporal changes in imprinting status in human islets.

scientific article published on 8 November 2012

LRIG2 mutations cause urofacial syndrome

scientific article

Maturation of induced pluripotent stem cell derived hepatocytes by 3D-culture

scientific article (publication date: 2014)

MicroRNA-122: a novel hepatocyte-enriched in vitro marker of drug-induced cellular toxicity.

scientific article

Muscarinic Acetylcholine Receptor M3 Mutation Causes Urinary Bladder Disease and a Prune-Belly-like Syndrome

scientific article published on November 2011

Novel SOX9 expression during human pancreas development correlates to abnormalities in Campomelic dysplasia

scientific article published in August 2002

Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans

scientific article published on September 2012

Periderm prevents pathological epithelial adhesions during embryogenesis.

scientific article

Perrault syndrome is caused by recessive mutations in CLPP, encoding a mitochondrial ATP-dependent chambered protease

scientific article published on 28 March 2013

Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes. ⬇️

scientific article

Phospholamban and sarcolipin are maintained in the endoplasmic reticulum by retrieval from the ER-Golgi intermediate compartment

scientific article published on 13 January 2007

SF-1: a critical mediator of steroidogenesis

scientific article published in January 2001

SRY, SOX9, and DAX1 expression patterns during human sex determination and gonadal development

scientific article

Stem cell marker TRA-1-60 is expressed in foetal and adult kidney and upregulated in tubulo-interstitial disease

scientific article published on 19 September 2010

Stem cell-derived hepatocytes as a predictive model for drug-induced liver injury: are we there yet?

scientific article

Steroidogenic enzyme expression within the adrenal cortex during early human gestation

scientific article published on 01 November 2002

Steroidogenic factor 1 (SF-1) is essential for ovarian development and function

scientific article

Subcellular localization of ALMS1 supports involvement of centrosome and basal body dysfunction in the pathogenesis of obesity, insulin resistance, and type 2 diabetes

scientific article

Survival in a case of life-threatening flecainide overdose

scientific article published on 01 July 1998

TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors

scientific article published on 27 April 2015

The adrenal cortex and sexual differentiation during early human development

scientific article published on March 2009

The diabetic phenotype in HNF4A mutation carriers is moderated by the expression of HNF4A isoforms from the P1 promoter during fetal development.

scientific article

The early human germ cell lineage does not express SOX2 during in vivo development or upon in vitro culture

scientific article published on 16 January 2008

The human fetal adrenal cortex and the window of sexual differentiation

scientific article published on 13 October 2006

The methyltransferase WBSCR22/Merm1 enhances glucocorticoid receptor function and is regulated in lung inflammation and cancer ⬇️

scientific article published on 31 January 2014

The self-orientation of mammalian cells in optical tweezers--the importance of the nucleus

scientific article

The soluble form of a disintegrin and metalloprotease 33 promotes angiogenesis: implications for airway remodeling in asthma.

scientific article published on 14 April 2008

The stress of starvation: glucocorticoid restraint of beta cell development

scientific article

The window period of NEUROGENIN3 during human gestation

scientific article

Tissue-specific knockouts of steroidogenic factor 1.

scientific article published on February 2004

Transcriptional regulation of the Alström syndrome gene ALMS1 by members of the RFX family and Sp1

scientific article

Understanding the role of SOX9 in acquired diseases: lessons from development

scientific article published on 13 January 2011

Weighing up beta-cell mass in mice and humans: self-renewal, progenitors or stem cells?

scientific article published on 16 March 2008

Wolcott-Rallison syndrome: pathogenic insights into neonatal diabetes from new mutation and expression studies of EIF2AK3.

scientific article published in September 2003

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