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List of works by Stephen M. Keyse

ACTION SPECTRA FOR INACTIVATION OF NORMAL and XERODERMA PIGMENTOSUM HUMAN SKIN FIBROBLASTS BY ULTRAVIOLET RADIATIONS

scientific article published on 01 March 1983

Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway

scientific journal article

Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway

Amino acid sequence similarity between CL100, a dual-specificity MAP kinase phosphatase and cdc25.

scientific article

An emerging family of dual specificity MAP kinase phosphatases ⬇️

scientific article published on March 16, 1995

BRAF inhibitor resistance: are holidays and cocktails the answer?

scientific article

Both binding and activation of p38 mitogen-activated protein kinase (MAPK) play essential roles in regulation of the nucleocytoplasmic distribution of MAPK-activated protein kinase 5 by cellular stress

scientific article

Both nuclear-cytoplasmic shuttling of the dual specificity phosphatase MKP-3 and its ability to anchor MAP kinase in the cytoplasm are mediated by a conserved nuclear export signal

scientific article

Cross-talk between the p38alpha and JNK MAPK pathways mediated by MAP kinase phosphatase-1 determines cellular sensitivity to UV radiation.

scientific article published on 11 June 2010

Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation

scientific article

DUSP6/MKP-3 inactivates ERK1/2 but fails to bind and inactivate ERK5.

scientific article published on 27 December 2007

Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases.

scientific article published on May 2007

Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1

scientific article (publication date: 11 May 2001)

Distinct docking mechanisms mediate interactions between the Msg5 phosphatase and mating or cell integrity mitogen-activated protein kinases (MAPKs) in Saccharomyces cerevisiae

scientific article published on 17 October 2011

Diverse physiological functions for dual-specificity MAP kinase phosphatases

scientific article published on November 2006

Docking of PRAK/MK5 to the atypical MAPKs ERK3 and ERK4 defines a novel MAPK interaction motif

scientific article published on 27 May 2009

Does MK5 reconcile classical and atypical MAP kinases?

scientific article published on 01 May 2008

Dual-specificity MAP kinase phosphatases (MKPs) and cancer

scientific article published on June 2008

Dual-specificity MAP kinase phosphatases (MKPs): shaping the outcome of MAP kinase signalling

scientific article

Dual-specificity MAP kinase phosphatases in health and disease

article

Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling

scientific article published on 04 January 2017

Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression

scientific article

Evidence that novobiocin and nalidixic acid do not inhibit excision repair in u.v.-irradiated human skin fibroblasts at a pre-incision step

scientific article published on August 1985

Excision Repair in u.v. (254 nm) Damaged Non-dividing Human Skin Fibroblasts: A Major Biological Role for DNA Polymerase Alpha

scientific article published on 01 November 1985

Excision repair in permeable arrested human skin fibroblasts damaged by UV (254 nm) radiation: Evidence that α- and β-polymerases act sequentially at the repolymerisation step

scholarly article by Stephen M. Keyse & R M Tyrrell published July 1985 in Mutation Research

Expression of the ERK-specific MAP kinase phosphatase PYST1/MKP3 in mouse embryos during morphogenesis and early organogenesis

scientific article published in May 2002

Feedback interactions between MKP3 and ERK MAP kinase control scleraxis expression and the specification of rib progenitors in the developing chick somite

scientific article

Gene trap mice reveal an essential function of dual specificity phosphatase Dusp16/MKP-7 in perinatal survival and regulation of Toll-like receptor (TLR)-induced cytokine production

scientific article published on 5 December 2013

Heat Shock Factor 1 Is a Substrate for p38 Mitogen-Activated Protein Kinases

scientific article published on 27 June 2016

Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines.

scientific article published on March 1995

Induction of the heme oxygenase gene in human skin fibroblasts by hydrogen peroxide and UVA (365 nm) radiation: evidence for the involvement of the hydroxyl radical.

scientific article published in May 1990

Jamming the signals ⬇️

scientific article published on 01 July 1995

MAP kinase inactivation is required only for G2-M phase transition in early embryogenesis cell cycles of the starfishes Marthasterias glacialis and Astropecten aranciacus.

scientific article published in October 1998

Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling.

scientific article published on 23 April 2001

Mutagenesis by hydrogen peroxide treatment of mammalian cells: a molecular analysis

scientific article published on February 1990

Negative feedback predominates over cross-regulation to control ERK MAPK activity in response to FGF signalling in embryos

scientific article published on 5 July 2006

Negative feedback regulation of FGF signaling levels by Pyst1/MKP3 in chick embryos.

scientific article

Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter

scientific article

Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry

scientific article published on February 1999

Phosphorylation of the kinase interaction motif in mitogen-activated protein (MAP) kinase phosphatase-4 mediates cross-talk between protein kinase A and MAP kinase signaling pathways

scientific article

Preface

scientific article published on 01 June 2008

Protein phosphatases and the regulation of mitogen-activated protein kinase signalling.

scientific article

Rapidly occurring DNA excision repair events determine the biological expression of u.v.-induced damage in human cells

scientific article published on 01 September 1987

Regulation of Caenorhabditis elegans p53/CEP-1-dependent germ cell apoptosis by Ras/MAPK signaling

scientific article

Regulation of MAPK-activated protein kinase 5 activity and subcellular localization by the atypical MAPK ERK4/MAPK4.

scientific article published on 13 September 2006

Regulation of atypical MAP kinases ERK3 and ERK4 by the phosphatase DUSP2.

scientific article published on 02 March 2017

Regulation of the inducible nuclear dual-specificity phosphatase DUSP5 by ERK MAPK.

scientific article published on 7 August 2009

Selective Expression of the MAPK Phosphatase Dusp9/MKP-4 in Mouse Plasmacytoid Dendritic Cells and Regulation of IFN-β Production

scientific article published on 13 July 2015

Spatio-temporal regulation of mitogen-activated protein kinase (MAPK) signalling by protein phosphatases.

scientific article published in November 2006

Specific inactivation and nuclear anchoring of extracellular signal-regulated kinase 2 by the inducible dual-specificity protein phosphatase DUSP5

scientific article

Synergistic activation of the mkp-1 gene by protein kinase A signaling and USF, but not c-Myc

article

The CL100 gene, which encodes a dual specificity (Tyr/Thr) MAP kinase phosphatase, is highly conserved and maps to human chromosome 5q34.

scientific article

The Ser(186) phospho-acceptor site within ERK4 is essential for its ability to interact with and activate PRAK/MK5.

scientific article published on May 2008

The dual-specificity protein phosphatase DUSP9/MKP-4 is essential for placental function but is not required for normal embryonic development

scientific article

The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy

scientific article published on 30 July 2019

The regulation of oncogenic Ras/ERK signalling by dual-specificity mitogen activated protein kinase phosphatases (MKPs)

scientific article

The response of normal and ataxia-telangiectasia human fibroblasts to the lethal effects of far, mid and near ultraviolet radiations

scientific article

The role of protein phosphatases in the regulation of mitogen and stress-activated protein kinases

scientific article

Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation

scientific article

Visualizing and Quantitating the Spatiotemporal Regulation of Ras/ERK Signaling by Dual-Specificity Mitogen-Activated Protein Phosphatases (MKPs).

scientific article published in January 2016

YIL113w encodes a functional dual-specificity protein phosphatase which specifically interacts with and inactivates the Slt2/Mpk1p MAP kinase in S. cerevisiae

scientific article

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