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List of works by Christos Tsatsanis

ACTH Action on the Adrenals

scientific article published on 24 April 2015

Aberrant expression of corticotropin-releasing hormone in pre-eclampsia induces expression of FasL in maternal macrophages and extravillous trophoblast apoptosis

scientific article

Ablation of tumor progression locus 2 promotes a type 2 Th cell response in Ovalbumin-immunized mice.

scientific article

Adiponectin induces TNF-alpha and IL-6 in macrophages and promotes tolerance to itself and other pro-inflammatory stimuli

scientific article published on October 2005

Adiponectin promotes endotoxin tolerance in macrophages by inducing IRAK-M expression.

scientific article published in May 2009

Akt Signaling Pathway in Macrophage Activation and M1/M2 Polarization.

scientific article published on February 2017

Akt2 deficiency protects from acute lung injury via alternative macrophage activation and miR-146a induction in mice.

scientific article

Alendronate reduces serum TNFalpha and IL-1beta, increases neutrophil counts, and improves bone mineral density and bone metabolism indices in patients with chronic idiopathic neutropenia (CIN)-associated osteopenia/osteoporosis

scientific article published in January 2004

Association between H1N1 infection severity and obesity-adiponectin as a potential etiologic factor

scientific article published on 01 August 2010

Association between regulator of G protein signaling 9-2 and body weight

scientific article (publication date: 2011)

Association of herpesvirus infection with the development of genital cancer.

scientific article

Baseline plasma levels of interleukin-8 in stage IV non-small-cell lung cancer patients: relationship with nutritional status and prognosis

scientific article published on 18 November 2011

Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis

scientific article published on 17 April 2018

Coordinated Regulation of miR-155 and miR-146a Genes during Induction of Endotoxin Tolerance in Macrophages

scientific article published on 4 November 2015

Correlation between serum 25-hydroxyvitamin D levels and quadriceps muscle strength in elderly cretans

scientific article published on 01 September 2010

Corticotrophin-Releasing Factor (CRF) and the urocortins are potent regulators of the inflammatory phenotype of human and mouse white adipocytes and the differentiation of mouse 3T3L1 pre-adipocytes

scientific article

Corticotropin Releasing Factor promotes breast cancer cell motility and invasiveness.

scientific article published on 02 June 2009

Corticotropin releasing factor receptor 1 (CRF1) and CRF2 agonists exert an anti-inflammatory effect during the early phase of inflammation suppressing LPS-induced TNF-alpha release from macrophages via induction of COX-2 and PGE2.

scientific article published on March 2007

Corticotropin-releasing factor (CRF) and the urocortins differentially regulate catecholamine secretion in human and rat adrenals, in a CRF receptor type-specific manner

scientific journal article

Corticotropin-releasing factor and the urocortins induce the expression of TLR4 in macrophages via activation of the transcription factors PU.1 and AP-1.

scientific article published on February 2006

Corticotropin-releasing hormone activates protein kinase C in an isoenzyme-specific manner

scientific journal article

Corticotropin-releasing hormone augments proinflammatory cytokine production from macrophages in vitro and in lipopolysaccharide-induced endotoxin shock in mice

scientific article

Corticotropin-releasing hormone induces Fas ligand production and apoptosis in PC12 cells via activation of p38 mitogen-activated protein kinase

scientific journal article

DNA damage triggers a chronic autoinflammatory response, leading to fat depletion in NER progeria

scientific article published on September 2013

Dehydroepiandrosterone and allopregnanolone protect sympathoadrenal medulla cells against apoptosis via antiapoptotic Bcl-2 proteins

scientific article

Dehydroepiandrosterone sulfate and allopregnanolone directly stimulate catecholamine production via induction of tyrosine hydroxylase and secretion by affecting actin polymerization.

scientific article

Dehydroepiandrosterone, as Endogenous Inhibitor of Neuronal Cell Apoptosis: Potential Therapeutic Implications in Neurodegenerative Diseases

Detection of epidermal growth-factor receptor and C-erbb-2 gene amplification in transitional-cell bladder-carcinoma using the differential PCR technique

scientific article published on 01 June 1994

Discrepancy between exercise performance, body composition, and sex steroid response after a six-week detraining period in professional soccer players

scientific article

Distinct roles of TLR4 and CD14 in LPS-induced inflammatory responses of neonates

scientific article published in August 2009

Disulfides from the Brown Alga Dictyopteris Membranacea Suppress M1 Macrophage Activation by Inducing AKT and Suppressing MAPK/ERK Signaling Pathways

scientific article published on 24 October 2020

Effect of different seasonal strength training protocols on circulating androgen levels and performance parameters in professional soccer players

scientific article published on 01 January 2014

Effects of hypoxia and hypercapnia on surfactant protein expression proliferation and apoptosis in A549 alveolar epithelial cells

scientific article published on 26 August 2005

Effects of respiratory rate on ventilator-induced lung injury at a constant PaCO2 in a mouse model of normal lung

scientific article published on 01 April 2008

Elderly patients with trochanteric hip fracture have lower serum Vitamin D levels compared to patients with cervical hip fracture

scientific article published on 27 April 2010

Epidermal growth factor receptor expression in squamous cell lung carcinomas: an immunohistochemical and gene analysis in formalin-fixed, paraffin-embedded material

scientific article published on 01 January 1993

Epigenetic and Transcriptional Regulation of IRAK-M Expression in Macrophages

scientific article published on 23 December 2016

Expansion of toll-like receptor 9-expressing B cells in active systemic lupus erythematosus: implications for the induction and maintenance of the autoimmune process

scientific article published on 01 November 2006

Expression of heregulin in human coronary atherosclerotic lesions.

scientific article published on 6 September 2005

Expression of the Tpl2/Cot oncogene in human T-cell neoplasias

scientific article

Feedback inhibition of human scavenger receptor class B type I gene expression by glucocorticoid in adrenal and ovarian cells.

scientific article

G protein-associated, specific membrane binding sites mediate the neuroprotective effect of dehydroepiandrosterone

scientific article published on 11 January 2006

Genetic and pharmacologic inhibition of Tpl2 kinase is protective in a mouse model of ventilator-induced lung injury

scientific article published on 9 May 2014

Genetic determinants of feline leukemia virus-induced lymphoid tumors: patterns of proviral insertion and gene rearrangement

scientific article published on December 1994

Helical optical projection tomography

scientific article published in November 2013

Hexamethylene bisacetamide and cis-platin stimulate the expression from the HIV-1 long terminal repeat sequence in human MCF-7 cells

scientific article published on March 1992

Histone methylation and acetylation in macrophages as a mechanism for regulation of inflammatory responses

article

Impaired clearance of apoptotic cells leads to HMGB1 release in the bone marrow of patients with myelodysplastic syndromes and induces TLR4-mediated cytokine production.

scientific article published on 12 February 2013

Increased levels of the high mobility group box 1 protein sustain the inflammatory bone marrow microenvironment in patients with chronic idiopathic neutropenia via activation of toll-like receptor 4

scientific article published on 30 November 2011

Insulin Resistance in Macrophages Alters Their Metabolism and Promotes an M2-Like Phenotype

scientific article published on 04 February 2019

Intercellular communication and human hepatocellular carcinoma.

scientific article

Interleukin-1 receptor-associated kinase-3 is a key inhibitor of inflammation in obesity and metabolic syndrome

scientific article

Intravital spectral imaging as a tool for accurate measurement of vascularization in mice

scientific article

Leishmania infantum and Toxoplasma gondii: Mixed infection of macrophages in vitro and in vivo.

scientific article published on 24 February 2011

Macrophage phenotype in sepsis immunosuppression

scientific article published on 16 March 2015

Mapping the CRF-urocortins system in human osteoarthritic and rheumatoid synovial fibroblasts: effect of vasoactive intestinal peptide.

scientific article

Mechanisms of retrovirus-induced oncogenesis

scientific article

Metabolic syndrome in early pregnancy and risk of preterm birth

scientific article published on 27 August 2009

MicroRNA-155 and Anti-Müllerian Hormone: New Potential Markers of Subfertility in Men with Chronic Kidney Disease

scientific article

Middle east respiratory syndrome corona virus spike glycoprotein suppresses macrophage responses via DPP4-mediated induction of IRAK-M and PPARγ.

scientific article published on 19 January 2017

Negative association between testosterone concentration and inflammatory markers in young men: a nested cross-sectional study

scientific article

Neorogioltriol and Related Diterpenes from the Red Alga Inhibit Inflammatory Bowel Disease in Mice by Suppressing M1 and Promoting M2-Like Macrophage Responses

article

Neuropeptide urocortin and its receptors are expressed in rat Kupffer cells

scientific article published on 03 November 2006

Neurosteroids as endogenous inhibitors of neuronal cell apoptosis in aging

scientific article published on November 2006

Normal ras genes: their onco-suppressor and pro-apoptotic functions (review).

scientific article

Overexpression of the Tpl-2/Cot oncogene in human breast cancer

scientific article published on 01 September 1999

PPAR agonist-induced reduction of Mcp1 in atherosclerotic plaques of obese, insulin-resistant mice depends on adiponectin-induced Irak3 expression

scientific article

Peripheral factors in the metabolic syndrome: the pivotal role of adiponectin.

scientific article published on November 2006

Phosphor-IWS1-dependent U2AF2 splicing regulates trafficking of CAR-E-positive intronless gene mRNAs and sensitivity to viral infection

scientific article published on 11 October 2021

Predictive and prognostic value of LPS-stimulated cytokine secretion in metastatic non-small cell lung cancer

scientific article published on 05 March 2013

Regulation of Endotoxin Tolerance and Compensatory Anti-inflammatory Response Syndrome by Non-coding RNAs

scientific article published on 20 November 2018

Roles of protein kinase A (PKA) and PKC on corticotropin-releasing hormone (CRH)-induced elevation of cytosolic calcium from extra-and intra-cellular sources.

scientific article published on October 2004

Serum miR-155 as a potential biomarker of male fertility

scientific article published on 3 March 2015

Sex hormone-dependent and -independent regulation of serum BAFF and TNF in cohorts of transgender and cisgender men and women

scientific article published in 2023

Stress neuropeptides in the human endometrium: paracrine effects on cell differentiation and apoptosis

scientific article published on 01 July 2002

The Tpl-2 protooncoprotein activates the nuclear factor of activated T cells and induces interleukin 2 expression in T cell lines.

scientific article

The application of the CRISPR-Cas9 genome editing machinery in food and agricultural science: Current status, future perspectives, and associated challenges

scientific article published on 16 February 2019

The calcineurin-nuclear factor of activated T cells signaling pathway mediates the effect of corticotropin releasing factor and urocortins on catecholamine synthesis

scientific article published in May 2012

The corticotropin-releasing factor (CRF) family of peptides as local modulators of adrenal function.

scientific article published on July 2007

The fit-1 common integration locus in human and mouse is closely linked to MYB.

scientific article

The gut microbiota in mouse models of inflammatory bowel disease

scientific article

The impact of adipose tissue-derived factors on the hypothalamic-pituitary-gonadal (HPG) axis

scientific article

The impact of stress on tumor growth: peripheral CRF mediates tumor-promoting effects of stress.

scientific article

The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs

scientific article

The metabolic syndrome in early pregnancy and risk of gestational diabetes mellitus

scientific article published in December 2009

The role of oncogenic kinases in human cancer (Review).

scientific article

Thuwalallenes A-E and Thuwalenynes A-C: New C15 Acetogenins with Anti-Inflammatory Activity from a Saudi Arabian Red Sea Laurencia sp

scientific article published on 15 November 2019

Tpl-2 induces IL-2 expression in T-cell lines by triggering multiple signaling pathways that activate NFAT and NF-kappaB

scientific article published on 01 November 1998

Tpl-2 induces apoptosis by promoting the assembly of protein complexes that contain caspase-9, the adapter protein Tvl-1, and procaspase-3.

scientific article published on May 2001

Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation

scientific article published on March 1997

Tpl2 ablation promotes intestinal inflammation and tumorigenesis in Apcmin mice by inhibiting IL-10 secretion and regulatory T-cell generation.

scientific article

Tpl2 and ERK transduce antiproliferative T cell receptor signals and inhibit transformation of chronically stimulated T cells.

scholarly article

Treatment of experimental murine colitis with CD40 antisense oligonucleotides delivered in amphoteric liposomes

scientific article published on 21 November 2012

Urocortin 1 and Urocortin 2 induce macrophage apoptosis via CRFR2

scientific article published on 01 August 2005

Urocortin in human gastric mucosa: relationship to inflammatory activity

scientific article published on 01 January 2003

Vasoactive intestinal peptide suppresses toll-like receptor 4 expression in macrophages via Akt1 reducing their responsiveness to lipopolysaccharide

scientific article

miRNA and Other Non-Coding RNAs as Promising Diagnostic Markers

scientific article published on 07 November 2018

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