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List of works by Aldo M Roccaro

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BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.

scientific article published on April 2013
CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy.

scientific article
Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features

scientific article published on March 6, 2012
Bortezomib mediates antiangiogenesis in multiple myeloma via direct and indirect effects on endothelial cells

scientific article published in January 2006
Targeting the bone marrow microenvironment in multiple myeloma.

scientific article
Bone marrow microenvironment in multiple myeloma progression.

scientific article published on 03 October 2012
Engineered nanomedicine for myeloma and bone microenvironment targeting.

scientific article
Regulation of microRNAs in cancer metastasis.

scientific article published on 22 February 2014
The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia

scientific article (publication date: 15 December 2007)
Honokiol overcomes conventional drug resistance in human multiple myeloma by induction of caspase-dependent and -independent apoptosis

scientific article
Increased incidence of transformation and myelodysplasia/acute leukemia in patients with Waldenström macroglobulinemia treated with nucleoside analogs

scientific article published on 8 December 2008
RhoA and Rac1 GTPases play major and differential roles in stromal cell-derived factor-1-induced cell adhesion and chemotaxis in multiple myeloma.

scientific article
Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition.

scientific article
Erythropoietin as an angiogenic factor.

scientific article published on October 2003
Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma

scientific article
LNA-mediated anti-miR-155 silencing in low-grade B-cell lymphomas

scientific article published on 13 July 2012
Clinical and translational studies of a phase II trial of the novel oral Akt inhibitor perifosine in relapsed or relapsed/refractory Waldenstrom's macroglobulinemia

scientific article
Dual targeting of the PI3K/Akt/mTOR pathway as an antitumor strategy in Waldenstrom macroglobulinemia.

scientific article
microRNA-dependent modulation of histone acetylation in Waldenstrom macroglobulinemia

scientific article
FTY720 induces apoptosis in multiple myeloma cells and overcomes drug resistance

scientific article published in August 2005
P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment

scientific article published on November 16, 2011
Metabolic signature identifies novel targets for drug resistance in multiple myeloma

scientific article published on 13 March 2015
Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model.

scientific article
Mast cell contribution to angiogenesis related to tumour progression.

scientific article
The sialyltransferase ST3GAL6 influences homing and survival in multiple myeloma

scientific article
C1013G/CXCR4 acts as a driver mutation of tumor progression and modulator of drug resistance in lymphoplasmacytic lymphoma

scientific article published on 07 April 2014
Defining the role of TORC1/2 in multiple myeloma

scientific article published on December 22, 2011
SDF-1 inhibition targets the bone marrow niche for cancer therapy

scientific article published on 25 September 2014
Weekly bortezomib in combination with temsirolimus in relapsed or relapsed and refractory multiple myeloma: a multicentre, phase 1/2, open-label, dose-escalation study

scientific article
CXCR4 Regulates Extra-Medullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation

scientific article published on 16 July 2015
Prognostic value of enhanced bone marrow angiogenesis in early B-cell chronic lymphocytic leukemia

scientific article published in November 2002
Selective inhibition of chymotrypsin-like activity of the immunoproteasome and constitutive proteasome in Waldenstrom macroglobulinemia

scientific article published on 28 January 2010
Role of endothelial progenitor cells in cancer progression

scientific article published on 04 April 2014
Bortezomib as an antitumor agent.

scientific article published on December 2006
The cancer glycome: carbohydrates as mediators of metastasis

scientific article
Targeting NF-kappaB in Waldenstrom macroglobulinemia

scientific article
Resveratrol exerts antiproliferative activity and induces apoptosis in Waldenström's macroglobulinemia

scientific article
Novel inosine monophosphate dehydrogenase inhibitor VX-944 induces apoptosis in multiple myeloma cells primarily via caspase-independent AIF/Endo G pathway

scientific article published on September 2005
The Mutational Landscape of Circulating Tumor Cells in Multiple Myeloma.

scientific article published on April 2017
Bone marrow angiogenesis in patients with active multiple myeloma.

scientific article
Novel targeting of phospho-cMET overcomes drug resistance and induces antitumor activity in multiple myeloma.

scientific article published on 26 June 2013
SDX-101, the R-enantiomer of etodolac, induces cytotoxicity, overcomes drug resistance, and enhances the activity of dexamethasone in multiple myeloma

scientific article
Pyk2 promotes tumor progression in multiple myeloma

scientific article
Targeting Akt and heat shock protein 90 produces synergistic multiple myeloma cell cytotoxicity in the bone marrow microenvironment

scientific article published on February 2008
Tryptase-positive mast cells correlate positively with bone marrow angiogenesis in B-cell chronic lymphocytic leukemia

scientific article published in July 2003
Vascular endothelial growth factor and its receptors in multiple myeloma.

scientific article
Kinetics of Th1/Th2 cytokines and lymphocyte subsets to predict chronic GVHD after allo-SCT: results of a prospective study.

scientific article published on 27 April 2009
Angiogenesis extent and expression of matrix metalloproteinase-2 and -9 agree with progression of ovarian endometriomas

scientific article published on 01 March 2002
Antimyeloma activity of two novel N-substituted and tetraflourinated thalidomide analogs

scientific article
Global epigenetic regulation of microRNAs in multiple myeloma

scientific article

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