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List of works by Holger Sültmann

A Cancer-Indicative microRNA Pattern in Normal Prostate Tissue.

scientific article published on 4 March 2013

A cancer specific hypermethylation signature of the TERT promoter predicts biochemical relapse in prostate cancer: a retrospective cohort study.

scientific article published on 16 July 2016

A field guide for cancer diagnostics using cell-free DNA: From principles to practice and clinical applications

scientific article

A simple strand-specific RNA-Seq library preparation protocol combining the Illumina TruSeq RNA and the dUTP methods ⬇️

scientific article published on May 15, 2012

Activation of AMP-activated protein kinase sensitizes lung cancer cells and H1299 xenografts to erlotinib

scientific article published on 10 September 2014

Ago-RIP-Seq identifies Polycomb repressive complex I member CBX7 as a major target of miR-375 in prostate cancer progression

scientific article published on 20 July 2016

Analysis of pigmented villonodular synovitis with genome-wide complementary DNA microarray and tissue array technology reveals insight into potential novel therapeutic approaches.

scholarly article

Antibody-mediated signal amplification for reverse phase protein array-based protein quantification

scientific article published in January 2011

BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence

scientific article

Characterization of transcriptional changes in ERG rearrangement-positive prostate cancer identifies the regulation of metabolic sensors such as neuropeptide Y.

scientific article

Circulating miRNAs are correlated with tumor progression in prostate cancer

scientific article published on 01 February 2011

Class I mhc genes of cichlid fishes: identification, expression, and polymorphism

scientific article published on 01 January 1997

Combinatorial RNAi for quantitative protein network analysis

scholarly article

Contact spotting of protein microarrays coupled with spike-in of normalizer protein permits time-resolved analysis of ERBB receptor signaling

scientific article

Correlation between genomic index lesions and mpMRI and Ga-PSMA-PET/CT imaging features in primary prostate cancer

scientific article published in Scientific Reports

Cross-talk between AMPK and EGFR dependent Signaling in Non-Small Cell Lung Cancer.

scientific article published on 09 June 2016

Detection of TP53 Mutations in Tissue or Liquid Rebiopsies at Progression Identifies ALK+ Lung Cancer Patients with Poor Survival

scientific article published on 21 January 2019

Die Urologie im Konzept der „Comprehensive Cancer Center“

scientific article published on 01 September 2013

Differential expression of apoptotic genes PDIA3 and MAP3K5 distinguishes between low- and high-risk prostate cancer

scientific article

Digital PCR After MALDI-Mass Spectrometry Imaging to Combine Proteomic Mapping and Identification of Activating Mutations in Pulmonary Adenocarcinoma

scientific article published on 15 October 2018

Discrimination of direct and indirect interactions in a network of regulatory effects

scientific article published in November 2007

ERBB2 and TOP2A in breast cancer: a comprehensive analysis of gene amplification, RNA levels, and protein expression and their influence on prognosis and prediction.

scientific article published on 6 April 2010

EZH2 depletion blocks the proliferation of colon cancer cells

scientific article

Early detection of lung cancer by molecular markers in endobronchial epithelial-lining fluid

scientific article published in June 2012

Effects of infiltrating lymphocytes and estrogen receptor on gene expression and prognosis in breast cancer

scientific article

Epigenomic profiling of non-small cell lung cancer xenografts uncover LRP12 DNA methylation as predictive biomarker for carboplatin resistance

scientific article published on 20 July 2018

Equivalence test in quantitative reverse transcription polymerase chain reaction: confirmation of reference genes suitable for normalization

scientific article published on 01 December 2004

Establishment and comparative characterization of novel squamous cell non-small cell lung cancer cell lines and their corresponding tumor tissue.

scientific article published on January 2012

Estimating large-scale signaling networks through nested effect models with intervention effects from microarray data

scientific article

Evolving therapeutic concepts in prostate cancer based on genome-wide analyses (review).

scientific article

Experimental design and data analysis of Ago-RIP-Seq experiments for the identification of microRNA targets

scientific article

Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment.

scientific article published on 19 March 2015

Extracellular vesicle-mediated transfer of genetic information between the hematopoietic system and the brain in response to inflammation

scientific article (publication date: June 2014)

FGF-2 is a driving force for chromosomal instability and a stromal factor associated with adverse clinico-pathological features in prostate cancer

scientific article published on 07 June 2018

From ORFeome to biology: a functional genomics pipeline

scientific article

Functional profiling: from microarrays via cell-based assays to novel tumor relevant modulators of the cell cycle

scientific article

Gene expression analysis of endobronchial epithelial lining fluid in the evaluation of indeterminate pulmonary nodules.

scientific article

Gene expression profiling unravels cancer-related hepatic molecular signatures in steatohepatitis but not in steatosis

scientific article

Genome-Based Classification and Therapy of Prostate Cancer

scientific article published on 02 September 2018

Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation

scientific article published on 28 August 2012

Genomic analysis reveals poor separation of human cardiomyopathies of ischemic and nonischemic etiologies

scientific article published on 22 April 2008

Genomic features of renal cell carcinoma with venous tumor thrombus.

scientific article

Global DNA methylation reflects spatial heterogeneity and molecular evolution of lung adenocarcinomas

article

Global gene expression analysis reveals specific patterns of cell junctions in non-small cell lung cancer subtypes.

scientific article published on 16 May 2008

Graph based fusion of miRNA and mRNA expression data improves clinical outcome prediction in prostate cancer

scientific article

Hepatitis B and D viruses exploit sodium taurocholate co-transporting polypeptide for species-specific entry into hepatocytes.

scientific article published on 19 December 2013

Hepatitis D virus replication is sensed by MDA5 and induces IFN-β/λ responses in hepatocytes.

scientific article published on 7 March 2018

Identification and meta-analysis of a small gene expression signature for the diagnosis of estrogen receptor status in invasive ductal breast cancer

scientific article published on December 2006

Identification and validation of clinically relevant molecular alterations in prostate cancer

scientific article published in March 2009

Identification and validation of clinically relevant molecular alterations in prostate cancer

scientific article published in September 2008

Identification of E6/E7-Dependent MicroRNAs in HPV-Positive Cancer Cells.

scientific article

Identification of aberrant chromosomal regions from gene expression microarray studies applied to human breast cancer

scientific article published on 28 June 2007

Identification of cellular targets for the human papillomavirus E6 and E7 oncogenes by RNA interference and transcriptome analyses

scientific article

Identification of clinically relevant protein targets in prostate cancer with 2D-DIGE coupled mass spectrometry and systems biology network platform

scientific article

In vitro-targeted gene identification in patients with hepatitis C using a genome-wide microarray technology

scientific article published on 01 February 2009

Increased KIT signalling with up-regulation of cyclin D correlates to accelerated proliferation and shorter disease-free survival in gastrointestinal stromal tumours (GISTs) with KIT exon 11 deletions.

scientific article

Increasing the sensitivity of reverse phase protein arrays by antibody-mediated signal amplification

scientific article published on 22 June 2010

Infrared-based protein detection arrays for quantitative proteomics

scientific article published on 01 February 2008

Integration of pathway knowledge into a reweighted recursive feature elimination approach for risk stratification of cancer patients

scientific article

Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer

scientific article

Intratumorale Heterogenität des Nierenzellkarzinoms

scientific article published on 01 June 2015

Isolation of mhc class II DMA and DMB cDNA sequences in a marsupial: the gray short-tailed opossum (Monodelphis domestica)

scientific article published on 01 November 1998

Long noncoding RNA: "LNCs" to cancer

scientific article published on 31 January 2014

Loss of 9p leads to p16INK4A down-regulation and enables RB/E2F1-dependent cell cycle promotion in gastrointestinal stromal tumours (GISTs).

scientific article published in July 2008

Loss of EpCAM expression in breast cancer derived serum exosomes: role of proteolytic cleavage

scientific article published on 20 May 2011

Low Input Whole-Exome Sequencing to Determine the Representation of the Tumor Exome in Circulating DNA of Non-Small Cell Lung Cancer Patients

scientific article

Major histocompatibility complex class II A genes in cichlid fishes: identification, expression, linkage relationships, and haplotype variation.

scientific article

Metastases and multiple myeloma generate distinct transcriptional footprints in osteocytes in vivo

scientific article

Mhc class I gene of African lungfish

scientific article

Mhc class II B gene evolution in East African cichlid fishes

scientific article published on June 2000

Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories

scientific article published on 01 December 2018

Molecular cancer phenotype in normal prostate tissue

scientific article

Molecular signatures in IASLC/ATS/ERS classified growth patterns of lung adenocarcinoma

scientific article published in PLoS ONE

Mutation analysis of circulating plasma DNA to determine response to EGFR tyrosine kinase inhibitor therapy of lung adenocarcinoma patients

scientific article published on 19 September 2016

Mutations in BRCA2 and taxane resistance in prostate cancer

scientific article

New family of Mhc class II A genes identified from cDNA sequences in the cichlid fish Aulonocara hansbaenschi.

scientific article

Next generation sequencing of the cellular and liquid fraction of pancreatic cyst fluid supports discrimination of IPMN from pseudocysts and reveals cases with multiple mutated driver clones: First findings from the prospective ZYSTEUS biomarker stu

scientific article published on 17 October 2018

Nonlinkage of major histocompatibility complex class I and class II loci in bony fishes

scientific article published in February 2000

Novel RNA markers in prostate cancer: functional considerations and clinical translation

scientific article

Organization of Mhc class II B genes in the zebrafish (Brachydanio rerio).

scientific article published on September 1994

PARP inhibition in BRCA2-mutated prostate cancer

scientific article

Pathways regulating the expression of the immunomodulatory protein glycodelin in non‑small cell lung cancer

article

Patient-specific molecular alterations are associated with metastatic clear cell renal cell cancer progressing under tyrosine kinase inhibitor therapy.

scientific article published on 23 May 2017

Peroxiredoxins 3 and 4 Are Overexpressed in Prostate Cancer Tissue and Affect the Proliferation of Prostate Cancer Cells in Vitro ⬇️

scientific article published on March 28, 2012

Polymorphism and estimation of the number of MhcCyca class I and class II genes in laboratory strains of the common carp (Cyprinus carpio L.).

scientific article published in March 1993

Predicting pathway membership via domain signatures.

scientific article published on August 2008

Prognostic role of E2F1 and members of the CDKN2A network in gastrointestinal stromal tumors.

scientific article published in September 2005

QSEA-modelling of genome-wide DNA methylation from sequencing enrichment experiments

scientific article

Reduced expression of vacuole membrane protein 1 affects the invasion capacity of tumor cells

scientific article

Reverse-phase protein arrays for application-orientated cancer research

scientific article published on 04 August 2009

Role of miR-34a as a suppressor of L1CAM in endometrial carcinoma

scientific article published on January 2014

Sensitivity and resistance towards isoliquiritigenin, doxorubicin and methotrexate in T cell acute lymphoblastic leukaemia cell lines by pharmacogenomics

scientific article published on 29 July 2010

Serial liquid biopsies for detection of treatment failure and profiling of resistance mechanisms in KLC1-ALK-rearranged lung cancer

scientific article published on 13 December 2019

Serum miR-142-3p is associated with early relapse in operable lung adenocarcinoma patients

scientific article published on 11 February 2013

Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity

scientific article published on 13 June 2016

Subtractive gene expression profiling of articular cartilage and mesenchymal stem cells: serpins as cartilage-relevant differentiation markers

scientific article

Systematic analysis of T7 RNA polymerase based in vitro linear RNA amplification for use in microarray experiments

scientific article

TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling.

scientific article

TMPRSS2:ERG gene fusion variants induce TGF-β signaling and epithelial to mesenchymal transition in human prostate cancer cells

scientific article

Targeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity

scientific article

The ERG-regulated LINC00920 promotes prostate cancer cell survival via the 14-3-3ε- FOXO pathway

scientific article published on 09 July 2020

The anterior gradient 2 (AGR2) gene is overexpressed in prostate cancer and may be useful as a urine sediment marker for prostate cancer detection.

scientific article

The differentiation antigen NY-BR-1 is a potential target for antibody-based therapies in breast cancer

scientific article

The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function.

scientific article published on February 2007

The maternal embryonic leucine zipper kinase (MELK) is upregulated in high-grade prostate cancer ⬇️

scientific article published on September 4, 2012

Transcription alterations of members of the ubiquitin-proteasome network in prostate carcinoma.

scientific article

[Gene expression profiling in lung cancer. Experimental research and clinical application]

scientific article published on 03 March 2009

[Microarrays for the identification of molecular markers in the diagnosis and therapy of renal cell carcinomas]

scientific article published on 01 March 2006

[Molecular high throughput research in prostate carcinoma]

scientific article published on 01 September 2007

arrayMagic: two-colour cDNA microarray quality control and preprocessing

scientific article published on 28 September 2004

microRNA biomarkers in body fluids of prostate cancer patients ⬇️

scientific article published on May 29, 2012

pathClass: an R-package for integration of pathway knowledge into support vector machines for biomarker discovery

scientific article published on 30 March 2011

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